Human papillomavirus 82

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Alphapapillomavirus; Alphapapillomavirus 5

Average proteome isoelectric point is 6.6

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 8 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q9IR59|Q9IR59_HPV82 Protein E6 OS=Human papillomavirus 82 OX=129724 GN=E6 PE=3 SV=1
MM1 pKa = 7.78RR2 pKa = 11.84GNVPQLKK9 pKa = 10.5DD10 pKa = 3.11IVLEE14 pKa = 3.96LTPQPEE20 pKa = 3.85IDD22 pKa = 3.84LQCYY26 pKa = 7.32EE27 pKa = 4.53QFDD30 pKa = 3.98SSDD33 pKa = 3.65EE34 pKa = 4.01EE35 pKa = 5.13DD36 pKa = 3.99EE37 pKa = 4.2VDD39 pKa = 4.7NMRR42 pKa = 11.84DD43 pKa = 3.27QPARR47 pKa = 11.84QAGQDD52 pKa = 2.73TCYY55 pKa = 10.27RR56 pKa = 11.84IKK58 pKa = 10.64VHH60 pKa = 6.51CCRR63 pKa = 11.84CSSVVQLAVEE73 pKa = 4.19SSGDD77 pKa = 3.47SLRR80 pKa = 11.84IFQQMLLGDD89 pKa = 4.73LSLVCPWCATNN100 pKa = 4.82

Molecular weight: 11.32 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|Q9IR56|Q9IR56_HPV82 Regulatory protein E2 OS=Human papillomavirus 82 OX=129724 GN=E2 PE=3 SV=1
MM1 pKa = 7.16YY2 pKa = 10.33LVPTAPRR9 pKa = 11.84HH10 pKa = 5.93PLLQLLNSYY19 pKa = 7.72RR20 pKa = 11.84TPPRR24 pKa = 11.84PIPIPPPRR32 pKa = 11.84APQKK36 pKa = 9.91PRR38 pKa = 11.84HH39 pKa = 6.24HH40 pKa = 6.71NNEE43 pKa = 3.84NDD45 pKa = 3.6SDD47 pKa = 4.38LLSPTPPQSPRR58 pKa = 11.84CPWTPATTKK67 pKa = 9.83YY68 pKa = 9.25TVEE71 pKa = 4.3LQAQTPEE78 pKa = 4.26GTSVQLKK85 pKa = 10.33LRR87 pKa = 11.84LL88 pKa = 3.6

Molecular weight: 9.96 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

8

0

8

2386

84

642

298.3

33.44

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.119 ± 0.299

3.185 ± 0.935

5.365 ± 0.801

4.736 ± 0.534

4.191 ± 0.605

5.532 ± 0.879

2.179 ± 0.202

5.323 ± 0.728

4.904 ± 0.757

7.879 ± 1.102

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.886 ± 0.303

4.484 ± 0.689

6.496 ± 1.393

4.946 ± 0.653

4.904 ± 0.942

7.586 ± 0.809

8.508 ± 1.194

6.287 ± 0.527

1.341 ± 0.282

4.149 ± 0.436
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski