Average proteome isoelectric point is 6.48

Acidic

pI < 6.8

6.8-7.4

pI > 7.4

Basic

    

All

Note: above files contain also dissociation constants (pKa)

Virtual 2D-PAGE plot for 2 proteins (isoelectric point calculated using IPC2_protein)

    

>tr|A0A076EA46|A0A076EA46_9VIRU Replicase OS=Blacklegged tick phlebovirus 1 OX=1526521 PE=4 SV=1
MM1 pKa = 7.48SRR3 pKa = 11.84LDD5 pKa = 3.44QLSQHH10 pKa = 5.89LVEE13 pKa = 4.56LTRR16 pKa = 11.84GRR18 pKa = 11.84EE19 pKa = 3.83PGLIVPDD26 pKa = 3.98EE27 pKa = 4.24SFIDD31 pKa = 3.69LGRR34 pKa = 11.84WQTPPIVQVTQGQGEE49 pKa = 4.3ILNIRR54 pKa = 11.84FPDD57 pKa = 3.86LEE59 pKa = 3.89QWRR62 pKa = 11.84SVSEE66 pKa = 3.93VSMTSIVEE74 pKa = 4.08EE75 pKa = 3.99SWPQEE80 pKa = 3.98RR81 pKa = 11.84VSHH84 pKa = 6.33LRR86 pKa = 11.84HH87 pKa = 6.96DD88 pKa = 3.77YY89 pKa = 9.75TAGFFCRR96 pKa = 11.84GLDD99 pKa = 3.46APLRR103 pKa = 11.84DD104 pKa = 3.82YY105 pKa = 11.39FKK107 pKa = 11.1VCRR110 pKa = 11.84DD111 pKa = 4.0DD112 pKa = 4.5NDD114 pKa = 3.56NLAPDD119 pKa = 4.23VIMTVGEE126 pKa = 4.11VTLVHH131 pKa = 6.61EE132 pKa = 5.05FATTRR137 pKa = 11.84STLEE141 pKa = 3.78TSALEE146 pKa = 4.22AYY148 pKa = 7.49QTKK151 pKa = 9.87KK152 pKa = 10.52LRR154 pKa = 11.84YY155 pKa = 8.7IPALAHH161 pKa = 6.4RR162 pKa = 11.84ARR164 pKa = 11.84TEE166 pKa = 3.5EE167 pKa = 4.26RR168 pKa = 11.84IVIFTITVVSPKK180 pKa = 9.76TVLSNLPLTLDD191 pKa = 3.9DD192 pKa = 4.17VKK194 pKa = 10.73EE195 pKa = 3.94LCVRR199 pKa = 11.84FRR201 pKa = 11.84VADD204 pKa = 3.79DD205 pKa = 4.16MVWQLQQMGILVSDD219 pKa = 4.19EE220 pKa = 3.99EE221 pKa = 4.81SEE223 pKa = 4.47DD224 pKa = 3.55RR225 pKa = 11.84EE226 pKa = 4.2KK227 pKa = 11.38AEE229 pKa = 3.88KK230 pKa = 10.29ARR232 pKa = 11.84RR233 pKa = 11.84TMAGIPFNWEE243 pKa = 3.3FQNRR247 pKa = 11.84VFPSCDD253 pKa = 2.91QSVYY257 pKa = 10.52DD258 pKa = 4.56ASKK261 pKa = 9.63SQPDD265 pKa = 3.25KK266 pKa = 10.99RR267 pKa = 11.84YY268 pKa = 9.94VAEE271 pKa = 3.9QVINAFKK278 pKa = 10.83NSEE281 pKa = 3.76AKK283 pKa = 10.36LRR285 pKa = 11.84EE286 pKa = 3.81DD287 pKa = 3.18HH288 pKa = 7.23FIPRR292 pKa = 11.84EE293 pKa = 4.01TNLSEE298 pKa = 5.48KK299 pKa = 10.46EE300 pKa = 3.93RR301 pKa = 11.84LDD303 pKa = 4.13LNLEE307 pKa = 4.12EE308 pKa = 4.61CVKK311 pKa = 10.82QIEE314 pKa = 4.75EE315 pKa = 4.46YY316 pKa = 10.38VNSVGEE322 pKa = 3.98GHH324 pKa = 6.1EE325 pKa = 4.28FKK327 pKa = 10.78PVDD330 pKa = 3.81TLSSVIPVPWWVLTRR345 pKa = 11.84GTGSNNISQAPVGKK359 pKa = 7.13PTHH362 pKa = 6.13MPSLGYY368 pKa = 10.86SNEE371 pKa = 3.95TTFNHH376 pKa = 7.5WISAWNHH383 pKa = 5.15AKK385 pKa = 9.43QHH387 pKa = 5.49PEE389 pKa = 3.42KK390 pKa = 8.74MTEE393 pKa = 3.94EE394 pKa = 4.03NVQDD398 pKa = 4.03EE399 pKa = 4.43LRR401 pKa = 11.84EE402 pKa = 4.11ALEE405 pKa = 3.97ATPEE409 pKa = 3.94NLEE412 pKa = 3.95LTEE415 pKa = 4.24KK416 pKa = 10.05QKK418 pKa = 11.15EE419 pKa = 3.95MTKK422 pKa = 10.56RR423 pKa = 11.84LDD425 pKa = 3.56SVLGRR430 pKa = 11.84MAKK433 pKa = 8.47PTSTTTRR440 pKa = 11.84SCYY443 pKa = 9.55RR444 pKa = 11.84RR445 pKa = 11.84VNVRR449 pKa = 11.84VSQEE453 pKa = 4.08DD454 pKa = 3.35EE455 pKa = 3.96RR456 pKa = 11.84EE457 pKa = 3.84AAKK460 pKa = 10.52RR461 pKa = 11.84GLRR464 pKa = 11.84GKK466 pKa = 10.35KK467 pKa = 8.73FARR470 pKa = 11.84DD471 pKa = 3.48NEE473 pKa = 4.48VNAHH477 pKa = 6.24HH478 pKa = 6.55EE479 pKa = 4.25QTKK482 pKa = 10.87LPFSLDD488 pKa = 3.37NHH490 pKa = 6.49VSDD493 pKa = 5.54IDD495 pKa = 3.88VLLDD499 pKa = 3.43KK500 pKa = 11.0AQSLLAHH507 pKa = 6.35VSSNRR512 pKa = 11.84NSYY515 pKa = 10.98DD516 pKa = 3.9RR517 pKa = 11.84DD518 pKa = 3.33ILPNLAEE525 pKa = 3.78QAYY528 pKa = 8.93ALHH531 pKa = 6.78GSDD534 pKa = 5.93VGDD537 pKa = 3.41PWIKK541 pKa = 10.6LLRR544 pKa = 11.84SWLTSDD550 pKa = 3.84LGKK553 pKa = 9.73WCSLVSDD560 pKa = 4.5IGTEE564 pKa = 3.9LAISMKK570 pKa = 8.01QHH572 pKa = 6.36CKK574 pKa = 9.35GNQMILKK581 pKa = 9.53KK582 pKa = 10.34LRR584 pKa = 11.84HH585 pKa = 6.21FDD587 pKa = 3.31LYY589 pKa = 10.82MLIRR593 pKa = 11.84PTSSKK598 pKa = 10.91SSIYY602 pKa = 9.58YY603 pKa = 10.33SLMTFEE609 pKa = 5.82SSLTNDD615 pKa = 3.66PGLAGTVFKK624 pKa = 11.08QSFSNGQIRR633 pKa = 11.84WTEE636 pKa = 3.92FNSVDD641 pKa = 3.89SSKK644 pKa = 11.14LMNMVKK650 pKa = 9.86CRR652 pKa = 11.84SIMYY656 pKa = 9.85TMLCYY661 pKa = 9.79WLEE664 pKa = 4.1FYY666 pKa = 10.7GLKK669 pKa = 10.15FWEE672 pKa = 4.49VDD674 pKa = 3.5LKK676 pKa = 10.26TQTPEE681 pKa = 3.45MDD683 pKa = 3.83EE684 pKa = 4.03VWRR687 pKa = 11.84MVLICLMIILDD698 pKa = 4.56DD699 pKa = 3.65KK700 pKa = 11.24TKK702 pKa = 9.86TEE704 pKa = 4.4EE705 pKa = 4.06IITTSRR711 pKa = 11.84YY712 pKa = 9.2IFMEE716 pKa = 4.38GFVAQPALPKK726 pKa = 7.68PHH728 pKa = 7.36KK729 pKa = 9.55MISKK733 pKa = 10.07LPTVLRR739 pKa = 11.84SRR741 pKa = 11.84LQVWLMHH748 pKa = 5.83RR749 pKa = 11.84TFTTMRR755 pKa = 11.84RR756 pKa = 11.84VASTPFHH763 pKa = 6.07MAWEE767 pKa = 4.66DD768 pKa = 3.67GRR770 pKa = 11.84PIWFGMFNMFTQQSLRR786 pKa = 11.84EE787 pKa = 3.97PMQLVSCFYY796 pKa = 11.02LGYY799 pKa = 10.39LKK801 pKa = 10.75NKK803 pKa = 9.78EE804 pKa = 4.2EE805 pKa = 4.25SPQGNSSSKK814 pKa = 10.42LYY816 pKa = 9.99EE817 pKa = 3.75KK818 pKa = 11.0VMEE821 pKa = 4.28YY822 pKa = 10.65EE823 pKa = 3.95SRR825 pKa = 11.84RR826 pKa = 11.84PKK828 pKa = 9.96TDD830 pKa = 3.26EE831 pKa = 3.62NLGWGDD837 pKa = 4.05PGLDD841 pKa = 2.73DD842 pKa = 4.51VKK844 pKa = 10.78FHH846 pKa = 6.28EE847 pKa = 5.05FSRR850 pKa = 11.84SFLLYY855 pKa = 10.69CADD858 pKa = 3.51QAIKK862 pKa = 10.42KK863 pKa = 9.25LEE865 pKa = 4.05SMYY868 pKa = 10.78GPRR871 pKa = 11.84VKK873 pKa = 10.73AQMTEE878 pKa = 4.15DD879 pKa = 3.0ILYY882 pKa = 10.75AIGNYY887 pKa = 9.69DD888 pKa = 4.02LEE890 pKa = 4.38QFATLKK896 pKa = 11.0ASATYY901 pKa = 9.47DD902 pKa = 3.2QSMYY906 pKa = 11.01DD907 pKa = 3.92YY908 pKa = 10.9DD909 pKa = 4.05PKK911 pKa = 10.68KK912 pKa = 9.76QYY914 pKa = 10.51HH915 pKa = 5.45RR916 pKa = 11.84AKK918 pKa = 10.23VVEE921 pKa = 4.42FVVKK925 pKa = 10.5NSEE928 pKa = 4.31KK929 pKa = 9.24ATHH932 pKa = 4.59VHH934 pKa = 6.42EE935 pKa = 4.97LLHH938 pKa = 6.3EE939 pKa = 4.38CLEE942 pKa = 4.14EE943 pKa = 4.48LEE945 pKa = 5.36KK946 pKa = 10.55NTCLHH951 pKa = 6.47IDD953 pKa = 4.05LFKK956 pKa = 10.72KK957 pKa = 9.61AQHH960 pKa = 5.69GGIRR964 pKa = 11.84EE965 pKa = 4.11IYY967 pKa = 9.58VLGPRR972 pKa = 11.84EE973 pKa = 4.11RR974 pKa = 11.84LVQLCLEE981 pKa = 5.05LIARR985 pKa = 11.84TICKK989 pKa = 9.84RR990 pKa = 11.84FPSEE994 pKa = 3.75TMMNPKK1000 pKa = 10.23NKK1002 pKa = 8.86TDD1004 pKa = 3.26LPQRR1008 pKa = 11.84HH1009 pKa = 5.61NKK1011 pKa = 7.56EE1012 pKa = 4.59AKK1014 pKa = 9.72DD1015 pKa = 3.28KK1016 pKa = 10.54CGPSFTTTATSDD1028 pKa = 4.71DD1029 pKa = 3.69AAKK1032 pKa = 9.68WNQGHH1037 pKa = 5.73FVSKK1041 pKa = 10.14FAMLLCRR1048 pKa = 11.84FTEE1051 pKa = 4.42PVLHH1055 pKa = 6.19PFIMRR1060 pKa = 11.84ACALFTRR1067 pKa = 11.84KK1068 pKa = 9.27IIKK1071 pKa = 9.84IDD1073 pKa = 3.7DD1074 pKa = 3.57QLLKK1078 pKa = 10.56IFAKK1082 pKa = 10.91YY1083 pKa = 8.94EE1084 pKa = 3.82DD1085 pKa = 3.96RR1086 pKa = 11.84VFGSEE1091 pKa = 4.72HH1092 pKa = 6.56IEE1094 pKa = 3.9LMHH1097 pKa = 6.49AAFRR1101 pKa = 11.84GRR1103 pKa = 11.84GDD1105 pKa = 3.22DD1106 pKa = 3.23RR1107 pKa = 11.84YY1108 pKa = 11.26GHH1110 pKa = 5.71VEE1112 pKa = 3.75PGKK1115 pKa = 8.7TFLKK1119 pKa = 10.04TEE1121 pKa = 3.81TGMLQGILHH1130 pKa = 6.01YY1131 pKa = 10.62SSSLLHH1137 pKa = 6.45TIYY1140 pKa = 10.75QEE1142 pKa = 3.96FLLDD1146 pKa = 4.52LIEE1149 pKa = 3.88ARR1151 pKa = 11.84FRR1153 pKa = 11.84HH1154 pKa = 5.33KK1155 pKa = 10.25HH1156 pKa = 4.63VLLKK1160 pKa = 10.51RR1161 pKa = 11.84KK1162 pKa = 8.25KK1163 pKa = 7.53TQLRR1167 pKa = 11.84PHH1169 pKa = 5.88ITVMQSSDD1177 pKa = 3.71DD1178 pKa = 3.91SSVMISFPVSTSVPQATSQGMVLAWICFQVKK1209 pKa = 10.01KK1210 pKa = 10.66EE1211 pKa = 4.03LGLLLGIYY1219 pKa = 9.74PSEE1222 pKa = 4.32KK1223 pKa = 9.74CTTNTPWIVEE1233 pKa = 4.23FNSEE1237 pKa = 4.5FFFLSDD1243 pKa = 4.65LIRR1246 pKa = 11.84PSFRR1250 pKa = 11.84WVAAANGLSEE1260 pKa = 4.77HH1261 pKa = 6.08EE1262 pKa = 4.35TLAGRR1267 pKa = 11.84QEE1269 pKa = 4.23EE1270 pKa = 4.43MSSNLTNVLGGGGTTSLTANVQLSQMMLHH1299 pKa = 5.35YY1300 pKa = 10.27QILGATTSLVFGHH1313 pKa = 6.28YY1314 pKa = 10.43SDD1316 pKa = 4.84MLAFMPDD1323 pKa = 3.23PSLGFFLLDD1332 pKa = 3.3HH1333 pKa = 7.16PFLAGIGGFKK1343 pKa = 10.6FNLYY1347 pKa = 10.25LAVKK1351 pKa = 8.74KK1352 pKa = 9.01TRR1354 pKa = 11.84LGEE1357 pKa = 3.88KK1358 pKa = 9.8YY1359 pKa = 10.23KK1360 pKa = 10.71RR1361 pKa = 11.84ILLGQQSAGPEE1372 pKa = 3.95RR1373 pKa = 11.84ADD1375 pKa = 2.82KK1376 pKa = 10.6GLRR1379 pKa = 11.84YY1380 pKa = 8.26RR1381 pKa = 11.84TLEE1384 pKa = 4.06TTKK1387 pKa = 10.35SGSIVEE1393 pKa = 4.17STIISMSTRR1402 pKa = 11.84KK1403 pKa = 9.54KK1404 pKa = 9.07WLTLITRR1411 pKa = 11.84MGLPEE1416 pKa = 3.99SWKK1419 pKa = 10.08EE1420 pKa = 4.68DD1421 pKa = 3.28VMTDD1425 pKa = 3.82QRR1427 pKa = 11.84VLYY1430 pKa = 9.44EE1431 pKa = 4.0KK1432 pKa = 10.71AHH1434 pKa = 5.93NPEE1437 pKa = 3.8QLRR1440 pKa = 11.84LRR1442 pKa = 11.84LSVFMHH1448 pKa = 6.14SPGVIASISSSGTVVRR1464 pKa = 11.84LVALSAYY1471 pKa = 9.38VLSKK1475 pKa = 10.67PVVQDD1480 pKa = 3.2RR1481 pKa = 11.84TDD1483 pKa = 3.61WYY1485 pKa = 11.13CDD1487 pKa = 3.36ANSLYY1492 pKa = 10.5QKK1494 pKa = 9.89QSLMATVAKK1503 pKa = 9.62DD1504 pKa = 3.72QPWANPPGEE1513 pKa = 4.39PVTMEE1518 pKa = 4.42DD1519 pKa = 3.72LQALFPQRR1527 pKa = 11.84EE1528 pKa = 4.26DD1529 pKa = 3.52YY1530 pKa = 11.34DD1531 pKa = 3.74DD1532 pKa = 4.63LEE1534 pKa = 4.61RR1535 pKa = 11.84VGQTFLRR1542 pKa = 11.84VTGSSVRR1549 pKa = 11.84PHH1551 pKa = 7.11RR1552 pKa = 11.84PRR1554 pKa = 11.84ITTKK1558 pKa = 10.35VQVTGASGSATMTLLNVVEE1577 pKa = 4.39DD1578 pKa = 2.9RR1579 pKa = 11.84WYY1581 pKa = 9.32GHH1583 pKa = 6.21KK1584 pKa = 10.28RR1585 pKa = 11.84YY1586 pKa = 7.65MAPPKK1591 pKa = 10.25TMEE1594 pKa = 4.26QLWSLAKK1601 pKa = 10.26QRR1603 pKa = 11.84IPWLEE1608 pKa = 3.94DD1609 pKa = 3.22TPEE1612 pKa = 3.92EE1613 pKa = 4.1TLEE1616 pKa = 4.14KK1617 pKa = 10.95SPFTEE1622 pKa = 4.08PVSLRR1627 pKa = 11.84NFIVGDD1633 pKa = 3.69PTKK1636 pKa = 10.24SRR1638 pKa = 11.84SVAVSGVPVKK1648 pKa = 10.62RR1649 pKa = 11.84GSGASNVFTMVAEE1662 pKa = 4.05NFAPNFKK1669 pKa = 10.63LGGSTDD1675 pKa = 3.41QAAKK1679 pKa = 10.41SLSEE1683 pKa = 3.79KK1684 pKa = 10.43FLWLRR1689 pKa = 11.84HH1690 pKa = 4.97SLALIAQGPYY1700 pKa = 9.4NNTMKK1705 pKa = 10.84GSMMRR1710 pKa = 11.84DD1711 pKa = 3.27LLAANPGLRR1720 pKa = 11.84VDD1722 pKa = 3.85ATAARR1727 pKa = 11.84TRR1729 pKa = 11.84RR1730 pKa = 11.84NCLAIIQNFVVNGDD1744 pKa = 3.31RR1745 pKa = 11.84RR1746 pKa = 11.84EE1747 pKa = 3.93TMQQIIEE1754 pKa = 4.35HH1755 pKa = 6.69RR1756 pKa = 11.84LGSLGSYY1763 pKa = 9.33IQPQRR1768 pKa = 11.84YY1769 pKa = 8.86ASPEE1773 pKa = 3.88DD1774 pKa = 3.72VANSPGCYY1782 pKa = 8.64PGYY1785 pKa = 9.18YY1786 pKa = 10.04GHH1788 pKa = 7.14GIWRR1792 pKa = 11.84GRR1794 pKa = 11.84YY1795 pKa = 9.23DD1796 pKa = 3.51RR1797 pKa = 11.84TCVEE1801 pKa = 3.56IHH1803 pKa = 5.36VQRR1806 pKa = 11.84SLKK1809 pKa = 10.44DD1810 pKa = 3.52EE1811 pKa = 4.46KK1812 pKa = 11.38NSISGLLVSTVDD1824 pKa = 3.82DD1825 pKa = 4.63LNNVMRR1831 pKa = 11.84FLRR1834 pKa = 11.84EE1835 pKa = 3.46WAEE1838 pKa = 3.82EE1839 pKa = 3.92HH1840 pKa = 7.14HH1841 pKa = 6.97CDD1843 pKa = 4.84NDD1845 pKa = 3.43KK1846 pKa = 11.35HH1847 pKa = 5.88FLKK1850 pKa = 10.75APEE1853 pKa = 4.27KK1854 pKa = 10.11LHH1856 pKa = 5.84GEE1858 pKa = 4.02RR1859 pKa = 11.84VARR1862 pKa = 11.84MLRR1865 pKa = 11.84FSTCAVGSGVAVHH1878 pKa = 6.07VDD1880 pKa = 3.08RR1881 pKa = 11.84RR1882 pKa = 11.84LKK1884 pKa = 10.35IGVSVEE1890 pKa = 4.01VYY1892 pKa = 10.15RR1893 pKa = 11.84EE1894 pKa = 3.62LSFTYY1899 pKa = 9.37RR1900 pKa = 11.84RR1901 pKa = 11.84GVIRR1905 pKa = 11.84IEE1907 pKa = 3.9ALEE1910 pKa = 4.15EE1911 pKa = 4.07NPFVPRR1917 pKa = 11.84RR1918 pKa = 11.84WSTLLSYY1925 pKa = 11.06ACRR1928 pKa = 11.84EE1929 pKa = 3.62NDD1931 pKa = 3.72IDD1933 pKa = 3.55ITRR1936 pKa = 11.84QGVSDD1941 pKa = 3.59VLNIVGAAKK1950 pKa = 10.58NKK1952 pKa = 9.54FVLPWLDD1959 pKa = 3.98CKK1961 pKa = 10.79PVDD1964 pKa = 4.44PEE1966 pKa = 4.71AFDD1969 pKa = 4.47LLEE1972 pKa = 4.17SAVFSNRR1979 pKa = 11.84GTSTNPLWTWGDD1991 pKa = 3.75EE1992 pKa = 4.18PTGIMDD1998 pKa = 3.93WRR2000 pKa = 11.84ALAARR2005 pKa = 11.84IRR2007 pKa = 11.84EE2008 pKa = 4.05LSEE2011 pKa = 4.02LEE2013 pKa = 3.69LRR2015 pKa = 11.84RR2016 pKa = 11.84RR2017 pKa = 11.84GILTMTAISDD2027 pKa = 3.29MDD2029 pKa = 4.24LPVRR2033 pKa = 11.84DD2034 pKa = 4.38ISPEE2038 pKa = 3.63PSVARR2043 pKa = 11.84EE2044 pKa = 3.87SDD2046 pKa = 4.12DD2047 pKa = 4.26NPLAYY2052 pKa = 10.14LYY2054 pKa = 10.61EE2055 pKa = 4.34EE2056 pKa = 4.52EE2057 pKa = 4.77EE2058 pKa = 4.36EE2059 pKa = 4.31GDD2061 pKa = 3.96EE2062 pKa = 4.81FNLMSNADD2070 pKa = 4.28LLTKK2074 pKa = 10.61VFDD2077 pKa = 4.03RR2078 pKa = 11.84FDD2080 pKa = 5.51AEE2082 pKa = 3.9MQEE2085 pKa = 4.26PVEE2088 pKa = 4.42CDD2090 pKa = 2.74VDD2092 pKa = 4.23AEE2094 pKa = 4.25EE2095 pKa = 4.58FNLVVEE2101 pKa = 5.35DD2102 pKa = 5.55LDD2104 pKa = 4.45FDD2106 pKa = 4.48LANHH2110 pKa = 6.47LEE2112 pKa = 4.12EE2113 pKa = 4.55MIKK2116 pKa = 10.58NYY2118 pKa = 10.73GMVQAEE2124 pKa = 4.27YY2125 pKa = 8.01EE2126 pKa = 4.48TRR2128 pKa = 11.84FSHH2131 pKa = 7.61PFMTKK2136 pKa = 10.42VIDD2139 pKa = 3.99EE2140 pKa = 5.19FIKK2143 pKa = 11.14DD2144 pKa = 3.59MGGPTQLSSILSTKK2158 pKa = 10.07EE2159 pKa = 3.48YY2160 pKa = 10.18PNYY2163 pKa = 10.43LSRR2166 pKa = 11.84EE2167 pKa = 4.11LILRR2171 pKa = 11.84LRR2173 pKa = 11.84FLLGWWDD2180 pKa = 3.42KK2181 pKa = 11.23RR2182 pKa = 11.84LTPVTRR2188 pKa = 11.84EE2189 pKa = 3.16RR2190 pKa = 11.84RR2191 pKa = 11.84RR2192 pKa = 11.84IKK2194 pKa = 10.34RR2195 pKa = 11.84SRR2197 pKa = 11.84PDD2199 pKa = 3.36LQDD2202 pKa = 4.45DD2203 pKa = 3.85LAEE2206 pKa = 4.14LL2207 pKa = 4.0

Molecular weight: 252.81 kDa
Isoelectric point according different methods:

>tr|A0A076EA46|A0A076EA46_9VIRU Replicase OS=Blacklegged tick phlebovirus 1 OX=1526521 PE=4 SV=1
MM1 pKa = 7.71AKK3 pKa = 10.32FNIADD8 pKa = 3.41TWKK11 pKa = 11.05NEE13 pKa = 3.6VAKK16 pKa = 10.78ADD18 pKa = 3.72FLLQKK23 pKa = 10.85GEE25 pKa = 4.03AKK27 pKa = 10.34AAEE30 pKa = 4.09AAKK33 pKa = 10.42EE34 pKa = 4.31SIRR37 pKa = 11.84QSYY40 pKa = 8.37QALPGKK46 pKa = 10.49GSARR50 pKa = 11.84FVRR53 pKa = 11.84LEE55 pKa = 3.54QWLDD59 pKa = 3.27QSLDD63 pKa = 2.75NWQRR67 pKa = 11.84AVKK70 pKa = 10.43ARR72 pKa = 11.84GEE74 pKa = 4.18VPEE77 pKa = 4.36GQEE80 pKa = 3.44WTPRR84 pKa = 11.84QPAVYY89 pKa = 9.92QKK91 pKa = 7.57PTPKK95 pKa = 10.31KK96 pKa = 7.09QTRR99 pKa = 11.84TSGPGPGVAGPSSSTLTPEE118 pKa = 3.87EE119 pKa = 3.78EE120 pKa = 4.36KK121 pKa = 10.67EE122 pKa = 4.02RR123 pKa = 11.84KK124 pKa = 8.98EE125 pKa = 4.01LAEE128 pKa = 4.0EE129 pKa = 4.27AAKK132 pKa = 10.39SWEE135 pKa = 3.94AAEE138 pKa = 4.23EE139 pKa = 4.05QQEE142 pKa = 4.43SEE144 pKa = 4.53EE145 pKa = 3.88EE146 pKa = 4.15TKK148 pKa = 10.47RR149 pKa = 11.84KK150 pKa = 10.04KK151 pKa = 9.77EE152 pKa = 3.85AEE154 pKa = 4.12EE155 pKa = 3.81KK156 pKa = 10.45KK157 pKa = 10.42KK158 pKa = 10.99RR159 pKa = 11.84EE160 pKa = 3.75DD161 pKa = 3.1RR162 pKa = 11.84RR163 pKa = 11.84RR164 pKa = 11.84EE165 pKa = 3.66EE166 pKa = 3.47EE167 pKa = 3.56RR168 pKa = 11.84RR169 pKa = 11.84RR170 pKa = 11.84EE171 pKa = 3.74EE172 pKa = 3.61RR173 pKa = 11.84RR174 pKa = 11.84ALEE177 pKa = 4.16RR178 pKa = 11.84EE179 pKa = 3.99QQRR182 pKa = 11.84EE183 pKa = 4.25GSRR186 pKa = 11.84GTTPTQPAMDD196 pKa = 3.62EE197 pKa = 3.88AAAVKK202 pKa = 10.2RR203 pKa = 11.84AADD206 pKa = 3.47QIAAQVAEE214 pKa = 4.63VEE216 pKa = 4.61QPAAPTPTAVYY227 pKa = 10.74ANRR230 pKa = 11.84LHH232 pKa = 5.69QRR234 pKa = 11.84PARR237 pKa = 11.84SVEE240 pKa = 3.81LLAALEE246 pKa = 4.38KK247 pKa = 10.29ACHH250 pKa = 5.21VLGVSAAEE258 pKa = 4.31GGLVEE263 pKa = 5.75GAEE266 pKa = 4.19TWGDD270 pKa = 3.57VLKK273 pKa = 11.0DD274 pKa = 3.07IGDD277 pKa = 4.2FSVSSDD283 pKa = 3.33LVAEE287 pKa = 4.78LKK289 pKa = 9.33TAYY292 pKa = 9.64EE293 pKa = 4.18FQGFDD298 pKa = 3.02AKK300 pKa = 10.77LVARR304 pKa = 11.84QMKK307 pKa = 9.7AAGVSLLHH315 pKa = 6.55RR316 pKa = 11.84AEE318 pKa = 4.21GDD320 pKa = 3.3RR321 pKa = 11.84AGGFMDD327 pKa = 4.94RR328 pKa = 11.84LTLVVIGLMRR338 pKa = 11.84GANLDD343 pKa = 3.55KK344 pKa = 10.69VRR346 pKa = 11.84KK347 pKa = 9.04GMRR350 pKa = 11.84EE351 pKa = 3.72ANRR354 pKa = 11.84ANFDD358 pKa = 3.75VLVKK362 pKa = 10.46HH363 pKa = 6.33YY364 pKa = 10.05GIQSKK369 pKa = 9.75PVDD372 pKa = 3.75SMAITLPRR380 pKa = 11.84VIATFPGMAMDD391 pKa = 3.79VLKK394 pKa = 10.84VAEE397 pKa = 4.69LGPVRR402 pKa = 11.84HH403 pKa = 5.74ATMTEE408 pKa = 4.0MVAGYY413 pKa = 8.49PRR415 pKa = 11.84EE416 pKa = 4.07MMFSAFPSLIPRR428 pKa = 11.84GVEE431 pKa = 4.0GVTEE435 pKa = 4.33ALLSAYY441 pKa = 10.33LLYY444 pKa = 10.0QHH446 pKa = 6.63HH447 pKa = 7.0VSMVINPDD455 pKa = 3.07YY456 pKa = 10.1KK457 pKa = 10.52TWDD460 pKa = 3.47LQKK463 pKa = 10.66QKK465 pKa = 11.26SSLEE469 pKa = 4.07GFARR473 pKa = 11.84AAMEE477 pKa = 4.22SEE479 pKa = 4.45YY480 pKa = 9.81VTQRR484 pKa = 11.84QRR486 pKa = 11.84VLRR489 pKa = 11.84LMEE492 pKa = 4.65EE493 pKa = 4.33GWVSVDD499 pKa = 3.08TDD501 pKa = 3.55GKK503 pKa = 10.74KK504 pKa = 10.07ISLTPAVASAINAAAVLYY522 pKa = 7.13QTRR525 pKa = 11.84KK526 pKa = 9.67

Molecular weight: 58.33 kDa
Isoelectric point according different methods:

Try ESI

ChTry ESI

ArgC ESI

LysN ESI

TryLysC ESI

Try MALDI

ChTry MALDI

ArgC MALDI

LysN MALDI

TryLysC MALDI

Try LTQ

ChTry LTQ

ArgC LTQ

LysN LTQ

TryLysC LTQ

Try MSlow

ChTry MSlow

ArgC MSlow

LysN MSlow

TryLysC MSlow

Try MShigh

ChTry MShigh

ArgC MShigh

LysN MShigh

TryLysC MShigh

For dipeptide frequency statistics click here

Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here