Amino acid dipepetide frequency for Eimeria praecox

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
78.736AlaAla: 78.736 ± 1.063
1.397AlaCys: 1.397 ± 0.029
4.599AlaAsp: 4.599 ± 0.075
7.185AlaGlu: 7.185 ± 0.103
2.184AlaPhe: 2.184 ± 0.028
6.43AlaGly: 6.43 ± 0.054
1.283AlaHis: 1.283 ± 0.022
2.24AlaIle: 2.24 ± 0.028
2.756AlaLys: 2.756 ± 0.041
7.101AlaLeu: 7.101 ± 0.072
1.036AlaMet: 1.036 ± 0.022
1.862AlaAsn: 1.862 ± 0.027
6.417AlaPro: 6.417 ± 0.092
2.895AlaGln: 2.895 ± 0.039
3.979AlaArg: 3.979 ± 0.043
7.732AlaSer: 7.732 ± 0.068
10.023AlaThr: 10.023 ± 0.128
6.278AlaVal: 6.278 ± 0.062
0.654AlaTrp: 0.654 ± 0.015
1.184AlaTyr: 1.184 ± 0.021
0.0AlaXaa: 0.0 ± 0.0
Cys
1.039CysAla: 1.039 ± 0.02
1.518CysCys: 1.518 ± 0.039
0.434CysAsp: 0.434 ± 0.012
0.607CysGlu: 0.607 ± 0.016
0.619CysPhe: 0.619 ± 0.014
1.073CysGly: 1.073 ± 0.026
0.218CysHis: 0.218 ± 0.009
0.655CysIle: 0.655 ± 0.015
0.479CysLys: 0.479 ± 0.014
1.853CysLeu: 1.853 ± 0.025
0.411CysMet: 0.411 ± 0.012
0.4CysAsn: 0.4 ± 0.013
0.72CysPro: 0.72 ± 0.04
0.399CysGln: 0.399 ± 0.014
1.014CysArg: 1.014 ± 0.019
2.56CysSer: 2.56 ± 0.041
0.728CysThr: 0.728 ± 0.017
0.891CysVal: 0.891 ± 0.016
0.23CysTrp: 0.23 ± 0.009
0.297CysTyr: 0.297 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
4.18AspAla: 4.18 ± 0.068
0.651AspCys: 0.651 ± 0.021
2.116AspAsp: 2.116 ± 0.049
2.582AspGlu: 2.582 ± 0.034
0.931AspPhe: 0.931 ± 0.021
2.232AspGly: 2.232 ± 0.035
0.404AspHis: 0.404 ± 0.012
1.535AspIle: 1.535 ± 0.024
1.432AspLys: 1.432 ± 0.043
2.818AspLeu: 2.818 ± 0.031
0.661AspMet: 0.661 ± 0.014
0.864AspAsn: 0.864 ± 0.017
1.792AspPro: 1.792 ± 0.028
0.924AspGln: 0.924 ± 0.02
2.595AspArg: 2.595 ± 0.08
3.474AspSer: 3.474 ± 0.042
2.259AspThr: 2.259 ± 0.039
1.976AspVal: 1.976 ± 0.03
0.362AspTrp: 0.362 ± 0.012
0.543AspTyr: 0.543 ± 0.013
0.0AspXaa: 0.0 ± 0.0
Glu
7.898GluAla: 7.898 ± 0.115
0.68GluCys: 0.68 ± 0.017
3.098GluAsp: 3.098 ± 0.043
8.989GluGlu: 8.989 ± 0.186
0.963GluPhe: 0.963 ± 0.02
4.779GluGly: 4.779 ± 0.06
0.92GluHis: 0.92 ± 0.019
1.47GluIle: 1.47 ± 0.025
2.797GluLys: 2.797 ± 0.054
4.343GluLeu: 4.343 ± 0.057
0.874GluMet: 0.874 ± 0.017
1.151GluAsn: 1.151 ± 0.024
1.971GluPro: 1.971 ± 0.028
5.636GluGln: 5.636 ± 0.082
3.787GluArg: 3.787 ± 0.062
2.897GluSer: 2.897 ± 0.037
4.457GluThr: 4.457 ± 0.078
2.611GluVal: 2.611 ± 0.04
0.468GluTrp: 0.468 ± 0.013
0.737GluTyr: 0.737 ± 0.014
0.0GluXaa: 0.0 ± 0.0
Phe
2.021PheAla: 2.021 ± 0.025
0.593PheCys: 0.593 ± 0.014
0.964PheAsp: 0.964 ± 0.023
1.16PheGlu: 1.16 ± 0.023
0.858PhePhe: 0.858 ± 0.018
1.301PheGly: 1.301 ± 0.026
0.38PheHis: 0.38 ± 0.011
0.775PheIle: 0.775 ± 0.017
0.741PheLys: 0.741 ± 0.015
2.303PheLeu: 2.303 ± 0.031
0.377PheMet: 0.377 ± 0.009
0.561PheAsn: 0.561 ± 0.014
1.052PhePro: 1.052 ± 0.021
0.656PheGln: 0.656 ± 0.016
1.132PheArg: 1.132 ± 0.023
1.931PheSer: 1.931 ± 0.026
0.851PheThr: 0.851 ± 0.019
1.562PheVal: 1.562 ± 0.026
0.226PheTrp: 0.226 ± 0.009
0.49PheTyr: 0.49 ± 0.014
0.0PheXaa: 0.0 ± 0.0
Gly
6.425GlyAla: 6.425 ± 0.072
1.111GlyCys: 1.111 ± 0.02
2.997GlyAsp: 2.997 ± 0.046
3.586GlyGlu: 3.586 ± 0.043
1.484GlyPhe: 1.484 ± 0.022
6.121GlyGly: 6.121 ± 0.097
0.759GlyHis: 0.759 ± 0.02
1.526GlyIle: 1.526 ± 0.029
1.613GlyLys: 1.613 ± 0.033
4.222GlyLeu: 4.222 ± 0.049
0.789GlyMet: 0.789 ± 0.019
1.106GlyAsn: 1.106 ± 0.022
3.597GlyPro: 3.597 ± 0.09
1.672GlyGln: 1.672 ± 0.028
3.115GlyArg: 3.115 ± 0.036
4.884GlySer: 4.884 ± 0.063
2.375GlyThr: 2.375 ± 0.039
3.179GlyVal: 3.179 ± 0.035
0.515GlyTrp: 0.515 ± 0.012
0.856GlyTyr: 0.856 ± 0.019
0.0GlyXaa: 0.0 ± 0.0
His
1.627HisAla: 1.627 ± 0.025
0.341HisCys: 0.341 ± 0.01
0.566HisAsp: 0.566 ± 0.015
1.245HisGlu: 1.245 ± 0.024
0.501HisPhe: 0.501 ± 0.013
0.865HisGly: 0.865 ± 0.019
1.734HisHis: 1.734 ± 0.059
0.7HisIle: 0.7 ± 0.015
0.771HisLys: 0.771 ± 0.016
2.23HisLeu: 2.23 ± 0.033
0.414HisMet: 0.414 ± 0.014
0.46HisAsn: 0.46 ± 0.011
1.338HisPro: 1.338 ± 0.022
3.489HisGln: 3.489 ± 0.074
1.438HisArg: 1.438 ± 0.021
1.549HisSer: 1.549 ± 0.021
0.989HisThr: 0.989 ± 0.019
0.831HisVal: 0.831 ± 0.019
0.182HisTrp: 0.182 ± 0.007
0.367HisTyr: 0.367 ± 0.012
0.0HisXaa: 0.0 ± 0.0
Ile
2.296IleAla: 2.296 ± 0.03
0.667IleCys: 0.667 ± 0.016
1.144IleAsp: 1.144 ± 0.02
1.724IleGlu: 1.724 ± 0.029
0.76IlePhe: 0.76 ± 0.015
1.213IleGly: 1.213 ± 0.025
0.626IleHis: 0.626 ± 0.015
1.149IleIle: 1.149 ± 0.048
1.09IleLys: 1.09 ± 0.02
2.132IleLeu: 2.132 ± 0.033
0.426IleMet: 0.426 ± 0.014
1.007IleAsn: 1.007 ± 0.034
1.389IlePro: 1.389 ± 0.023
1.331IleGln: 1.331 ± 0.022
1.54IleArg: 1.54 ± 0.027
2.341IleSer: 2.341 ± 0.032
1.144IleThr: 1.144 ± 0.025
1.311IleVal: 1.311 ± 0.023
0.24IleTrp: 0.24 ± 0.009
0.556IleTyr: 0.556 ± 0.013
0.0IleXaa: 0.0 ± 0.0
Lys
2.939LysAla: 2.939 ± 0.045
0.44LysCys: 0.44 ± 0.014
1.455LysAsp: 1.455 ± 0.027
3.34LysGlu: 3.34 ± 0.07
0.511LysPhe: 0.511 ± 0.016
2.18LysGly: 2.18 ± 0.039
0.814LysHis: 0.814 ± 0.017
0.982LysIle: 0.982 ± 0.022
2.583LysLys: 2.583 ± 0.072
2.557LysLeu: 2.557 ± 0.036
0.551LysMet: 0.551 ± 0.013
0.903LysAsn: 0.903 ± 0.019
1.68LysPro: 1.68 ± 0.036
3.888LysGln: 3.888 ± 0.051
2.437LysArg: 2.437 ± 0.035
1.741LysSer: 1.741 ± 0.028
1.953LysThr: 1.953 ± 0.033
1.247LysVal: 1.247 ± 0.025
0.252LysTrp: 0.252 ± 0.009
0.559LysTyr: 0.559 ± 0.014
0.0LysXaa: 0.0 ± 0.0
Leu
5.876LeuAla: 5.876 ± 0.059
1.503LeuCys: 1.503 ± 0.026
2.597LeuAsp: 2.597 ± 0.036
4.373LeuGlu: 4.373 ± 0.061
2.13LeuPhe: 2.13 ± 0.033
3.826LeuGly: 3.826 ± 0.05
2.38LeuHis: 2.38 ± 0.03
1.936LeuIle: 1.936 ± 0.028
3.049LeuLys: 3.049 ± 0.043
16.909LeuLeu: 16.909 ± 0.207
1.392LeuMet: 1.392 ± 0.026
1.722LeuAsn: 1.722 ± 0.029
5.316LeuPro: 5.316 ± 0.053
12.292LeuGln: 12.292 ± 0.161
5.754LeuArg: 5.754 ± 0.055
6.259LeuSer: 6.259 ± 0.06
2.989LeuThr: 2.989 ± 0.036
3.48LeuVal: 3.48 ± 0.043
0.867LeuTrp: 0.867 ± 0.015
1.399LeuTyr: 1.399 ± 0.02
0.0LeuXaa: 0.0 ± 0.0
Met
0.966MetAla: 0.966 ± 0.021
0.213MetCys: 0.213 ± 0.008
0.436MetAsp: 0.436 ± 0.011
0.842MetGlu: 0.842 ± 0.017
0.318MetPhe: 0.318 ± 0.011
0.813MetGly: 0.813 ± 0.022
0.408MetHis: 0.408 ± 0.012
0.373MetIle: 0.373 ± 0.015
0.705MetLys: 0.705 ± 0.014
1.801MetLeu: 1.801 ± 0.025
0.414MetMet: 0.414 ± 0.022
0.341MetAsn: 0.341 ± 0.011
0.73MetPro: 0.73 ± 0.015
1.593MetGln: 1.593 ± 0.027
0.989MetArg: 0.989 ± 0.017
0.831MetSer: 0.831 ± 0.018
0.554MetThr: 0.554 ± 0.013
0.57MetVal: 0.57 ± 0.018
0.159MetTrp: 0.159 ± 0.007
0.265MetTyr: 0.265 ± 0.01
0.0MetXaa: 0.0 ± 0.0
Asn
1.85AsnAla: 1.85 ± 0.031
0.497AsnCys: 0.497 ± 0.013
0.78AsnAsp: 0.78 ± 0.018
1.169AsnGlu: 1.169 ± 0.023
0.478AsnPhe: 0.478 ± 0.014
1.153AsnGly: 1.153 ± 0.025
0.338AsnHis: 0.338 ± 0.01
1.001AsnIle: 1.001 ± 0.025
1.23AsnLys: 1.23 ± 0.028
1.511AsnLeu: 1.511 ± 0.026
0.364AsnMet: 0.364 ± 0.012
2.394AsnAsn: 2.394 ± 0.083
1.245AsnPro: 1.245 ± 0.022
0.803AsnGln: 0.803 ± 0.017
1.312AsnArg: 1.312 ± 0.023
5.794AsnSer: 5.794 ± 0.117
1.587AsnThr: 1.587 ± 0.033
0.911AsnVal: 0.911 ± 0.02
0.164AsnTrp: 0.164 ± 0.006
0.379AsnTyr: 0.379 ± 0.011
0.0AsnXaa: 0.0 ± 0.0
Pro
6.767ProAla: 6.767 ± 0.074
0.791ProCys: 0.791 ± 0.026
1.476ProAsp: 1.476 ± 0.03
2.704ProGlu: 2.704 ± 0.042
1.347ProPhe: 1.347 ± 0.027
2.37ProGly: 2.37 ± 0.044
1.395ProHis: 1.395 ± 0.021
1.133ProIle: 1.133 ± 0.024
1.601ProLys: 1.601 ± 0.039
5.284ProLeu: 5.284 ± 0.063
0.704ProMet: 0.704 ± 0.017
0.96ProAsn: 0.96 ± 0.017
5.717ProPro: 5.717 ± 0.087
3.916ProGln: 3.916 ± 0.058
2.457ProArg: 2.457 ± 0.034
4.837ProSer: 4.837 ± 0.054
2.883ProThr: 2.883 ± 0.039
2.533ProVal: 2.533 ± 0.04
0.56ProTrp: 0.56 ± 0.014
0.829ProTyr: 0.829 ± 0.017
0.0ProXaa: 0.0 ± 0.0
Gln
3.215GlnAla: 3.215 ± 0.045
0.468GlnCys: 0.468 ± 0.014
1.804GlnAsp: 1.804 ± 0.027
5.721GlnGlu: 5.721 ± 0.077
0.708GlnPhe: 0.708 ± 0.015
2.633GlnGly: 2.633 ± 0.036
5.292GlnHis: 5.292 ± 0.092
1.404GlnIle: 1.404 ± 0.021
3.019GlnLys: 3.019 ± 0.046
9.018GlnLeu: 9.018 ± 0.129
1.16GlnMet: 1.16 ± 0.022
1.052GlnAsn: 1.052 ± 0.021
3.398GlnPro: 3.398 ± 0.055
95.874GlnGln: 95.874 ± 1.319
5.047GlnArg: 5.047 ± 0.066
2.117GlnSer: 2.117 ± 0.028
2.534GlnThr: 2.534 ± 0.029
2.001GlnVal: 2.001 ± 0.03
0.452GlnTrp: 0.452 ± 0.012
0.68GlnTyr: 0.68 ± 0.017
0.0GlnXaa: 0.0 ± 0.0
Arg
4.173ArgAla: 4.173 ± 0.044
1.201ArgCys: 1.201 ± 0.021
2.532ArgAsp: 2.532 ± 0.06
4.192ArgGlu: 4.192 ± 0.06
1.229ArgPhe: 1.229 ± 0.023
3.737ArgGly: 3.737 ± 0.049
1.416ArgHis: 1.416 ± 0.023
1.626ArgIle: 1.626 ± 0.023
2.313ArgLys: 2.313 ± 0.032
5.293ArgLeu: 5.293 ± 0.053
1.063ArgMet: 1.063 ± 0.017
1.32ArgAsn: 1.32 ± 0.023
2.319ArgPro: 2.319 ± 0.03
4.717ArgGln: 4.717 ± 0.064
5.644ArgArg: 5.644 ± 0.079
4.495ArgSer: 4.495 ± 0.049
2.104ArgThr: 2.104 ± 0.028
2.474ArgVal: 2.474 ± 0.033
0.619ArgTrp: 0.619 ± 0.014
0.848ArgTyr: 0.848 ± 0.016
0.0ArgXaa: 0.0 ± 0.0
Ser
7.176SerAla: 7.176 ± 0.06
1.87SerCys: 1.87 ± 0.032
2.515SerAsp: 2.515 ± 0.035
3.306SerGlu: 3.306 ± 0.036
2.026SerPhe: 2.026 ± 0.031
4.136SerGly: 4.136 ± 0.055
1.156SerHis: 1.156 ± 0.02
2.426SerIle: 2.426 ± 0.041
3.0SerLys: 3.0 ± 0.034
6.432SerLeu: 6.432 ± 0.058
1.011SerMet: 1.011 ± 0.019
5.91SerAsn: 5.91 ± 0.121
4.84SerPro: 4.84 ± 0.059
2.344SerGln: 2.344 ± 0.032
4.985SerArg: 4.985 ± 0.048
32.918SerSer: 32.918 ± 0.51
4.252SerThr: 4.252 ± 0.052
3.565SerVal: 3.565 ± 0.039
0.682SerTrp: 0.682 ± 0.016
1.066SerTyr: 1.066 ± 0.019
0.001SerXaa: 0.001 ± 0.0
Thr
11.67ThrAla: 11.67 ± 0.135
0.64ThrCys: 0.64 ± 0.018
1.988ThrAsp: 1.988 ± 0.041
3.623ThrGlu: 3.623 ± 0.064
0.863ThrPhe: 0.863 ± 0.019
2.576ThrGly: 2.576 ± 0.038
0.824ThrHis: 0.824 ± 0.015
1.198ThrIle: 1.198 ± 0.026
1.493ThrLys: 1.493 ± 0.029
3.157ThrLeu: 3.157 ± 0.034
0.497ThrMet: 0.497 ± 0.014
1.43ThrAsn: 1.43 ± 0.037
3.543ThrPro: 3.543 ± 0.042
1.927ThrGln: 1.927 ± 0.023
2.08ThrArg: 2.08 ± 0.03
3.569ThrSer: 3.569 ± 0.041
4.396ThrThr: 4.396 ± 0.069
2.202ThrVal: 2.202 ± 0.036
0.322ThrTrp: 0.322 ± 0.01
0.65ThrTyr: 0.65 ± 0.018
0.0ThrXaa: 0.0 ± 0.0
Val
5.508ValAla: 5.508 ± 0.06
1.069ValCys: 1.069 ± 0.019
1.958ValAsp: 1.958 ± 0.031
2.894ValGlu: 2.894 ± 0.043
1.366ValPhe: 1.366 ± 0.022
2.78ValGly: 2.78 ± 0.035
0.847ValHis: 0.847 ± 0.018
1.067ValIle: 1.067 ± 0.025
1.411ValLys: 1.411 ± 0.023
4.687ValLeu: 4.687 ± 0.049
0.721ValMet: 0.721 ± 0.019
0.888ValAsn: 0.888 ± 0.018
2.136ValPro: 2.136 ± 0.035
2.116ValGln: 2.116 ± 0.033
2.212ValArg: 2.212 ± 0.032
4.003ValSer: 4.003 ± 0.044
1.415ValThr: 1.415 ± 0.03
2.874ValVal: 2.874 ± 0.044
0.483ValTrp: 0.483 ± 0.012
1.173ValTyr: 1.173 ± 0.037
0.0ValXaa: 0.0 ± 0.0
Trp
0.575TrpAla: 0.575 ± 0.013
0.165TrpCys: 0.165 ± 0.008
0.302TrpAsp: 0.302 ± 0.01
0.481TrpGlu: 0.481 ± 0.011
0.192TrpPhe: 0.192 ± 0.008
0.854TrpGly: 0.854 ± 0.017
0.161TrpHis: 0.161 ± 0.006
0.268TrpIle: 0.268 ± 0.009
0.341TrpLys: 0.341 ± 0.011
0.923TrpLeu: 0.923 ± 0.018
0.177TrpMet: 0.177 ± 0.007
0.192TrpAsn: 0.192 ± 0.008
0.327TrpPro: 0.327 ± 0.01
0.544TrpGln: 0.544 ± 0.013
0.814TrpArg: 0.814 ± 0.017
0.518TrpSer: 0.518 ± 0.013
0.288TrpThr: 0.288 ± 0.011
0.364TrpVal: 0.364 ± 0.011
0.145TrpTrp: 0.145 ± 0.006
0.099TrpTyr: 0.099 ± 0.005
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.033TyrAla: 1.033 ± 0.019
0.331TyrCys: 0.331 ± 0.016
0.571TyrAsp: 0.571 ± 0.016
0.803TyrGlu: 0.803 ± 0.018
0.465TyrPhe: 0.465 ± 0.011
0.86TyrGly: 0.86 ± 0.019
0.28TyrHis: 0.28 ± 0.009
0.619TyrIle: 0.619 ± 0.015
0.589TyrLys: 0.589 ± 0.015
1.476TyrLeu: 1.476 ± 0.023
0.28TyrMet: 0.28 ± 0.01
0.437TyrAsn: 0.437 ± 0.013
0.736TyrPro: 0.736 ± 0.017
0.582TyrGln: 0.582 ± 0.014
0.984TyrArg: 0.984 ± 0.023
1.169TyrSer: 1.169 ± 0.021
0.865TyrThr: 0.865 ± 0.017
0.747TyrVal: 0.747 ± 0.017
0.149TyrTrp: 0.149 ± 0.008
0.338TyrTyr: 0.338 ± 0.012
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.001XaaLys: 0.001 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7635 proteins (3653206 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski