Akkermansia glycaniphila

Taxonomy: cellular organisms; Bacteria; PVC group; Verrucomicrobia; Verrucomicrobiae; Verrucomicrobiales; Akkermansiaceae; Akkermansia

Average proteome isoelectric point is 6.47

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2530 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|A0A1C7PEE3|A0A1C7PEE3_9BACT von willebrand factor type a OS=Akkermansia glycaniphila OX=1679444 GN=PYTT_0121 PE=4 SV=1
MM1 pKa = 7.57SNNIPDD7 pKa = 3.83NLLYY11 pKa = 10.98SRR13 pKa = 11.84DD14 pKa = 4.03HH15 pKa = 6.36EE16 pKa = 4.49WVDD19 pKa = 3.28VDD21 pKa = 5.38GDD23 pKa = 3.55IATIGISDD31 pKa = 4.01HH32 pKa = 6.44AQAEE36 pKa = 4.33LGDD39 pKa = 4.07VVFVDD44 pKa = 4.81LPEE47 pKa = 5.27PGTSIAANDD56 pKa = 3.99SIAVVEE62 pKa = 4.45SVKK65 pKa = 10.63AASDD69 pKa = 3.79VYY71 pKa = 11.15SPVSGEE77 pKa = 3.64IIEE80 pKa = 4.34VNEE83 pKa = 3.99EE84 pKa = 3.98LGNEE88 pKa = 3.97PGAVNSDD95 pKa = 3.58PYY97 pKa = 11.06GNGWICKK104 pKa = 9.27IRR106 pKa = 11.84LQDD109 pKa = 3.54MSEE112 pKa = 4.14LDD114 pKa = 3.97SLLSPADD121 pKa = 3.49YY122 pKa = 11.47SEE124 pKa = 4.58FCSS127 pKa = 3.96

Molecular weight:
13.6 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|A0A1H6M0L2|A0A1H6M0L2_9BACT 6-phosphofructokinase OS=Akkermansia glycaniphila OX=1679444 GN=PYTT_1977 PE=4 SV=1
MM1 pKa = 7.41LLVEE5 pKa = 4.53KK6 pKa = 9.23TAKK9 pKa = 9.92RR10 pKa = 11.84LKK12 pKa = 10.72SGGLPPVRR20 pKa = 11.84KK21 pKa = 9.87NGLLRR26 pKa = 11.84RR27 pKa = 11.84RR28 pKa = 11.84GFGKK32 pKa = 10.49APARR36 pKa = 11.84LLPPAIRR43 pKa = 11.84MGKK46 pKa = 9.97NIGHH50 pKa = 6.3GAKK53 pKa = 10.28KK54 pKa = 10.22LFEE57 pKa = 4.24TGRR60 pKa = 11.84PPKK63 pKa = 10.34RR64 pKa = 11.84RR65 pKa = 11.84TKK67 pKa = 10.22PILRR71 pKa = 11.84HH72 pKa = 5.43RR73 pKa = 11.84RR74 pKa = 11.84SKK76 pKa = 10.56IRR78 pKa = 11.84TKK80 pKa = 8.6QRR82 pKa = 11.84KK83 pKa = 7.33IAGRR87 pKa = 11.84QIQSRR92 pKa = 11.84RR93 pKa = 11.84RR94 pKa = 11.84IARR97 pKa = 11.84RR98 pKa = 11.84LLARR102 pKa = 11.84HH103 pKa = 5.76RR104 pKa = 11.84QPPQLLPRR112 pKa = 11.84RR113 pKa = 11.84AQRR116 pKa = 11.84THH118 pKa = 6.53LRR120 pKa = 11.84HH121 pKa = 6.19KK122 pKa = 10.11PPEE125 pKa = 3.86PRR127 pKa = 11.84LIRR130 pKa = 11.84RR131 pKa = 11.84SGTRR135 pKa = 11.84LSPPPGSPRR144 pKa = 11.84HH145 pKa = 6.08IPHH148 pKa = 6.32EE149 pKa = 3.74QRR151 pKa = 11.84IRR153 pKa = 11.84IRR155 pKa = 11.84LRR157 pKa = 11.84LRR159 pKa = 11.84MEE161 pKa = 3.92RR162 pKa = 11.84QTTVNRR168 pKa = 11.84RR169 pKa = 11.84PAPLILPRR177 pKa = 11.84PRR179 pKa = 11.84PLRR182 pKa = 11.84LRR184 pKa = 11.84LHH186 pKa = 6.94PLPEE190 pKa = 4.54ILNLQIRR197 pKa = 11.84PLLHH201 pKa = 6.97RR202 pKa = 11.84VQTDD206 pKa = 3.22KK207 pKa = 11.51AHH209 pKa = 6.8PLAFTEE215 pKa = 4.63TAGNTSFTHH224 pKa = 7.4LIDD227 pKa = 3.62LQRR230 pKa = 11.84IQMRR234 pKa = 11.84AQHH237 pKa = 5.69SRR239 pKa = 11.84AGIIAAVIVRR249 pKa = 11.84HH250 pKa = 5.98RR251 pKa = 11.84KK252 pKa = 7.43QAAVKK257 pKa = 9.92HH258 pKa = 5.46LRR260 pKa = 11.84LPITEE265 pKa = 3.94RR266 pKa = 11.84SKK268 pKa = 9.96TIRR271 pKa = 11.84SQNRR275 pKa = 11.84SSS277 pKa = 3.07

Molecular weight:
32.26 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2530

0

2530

925710

32

4417

365.9

40.36

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

9.942 ± 0.062

1.442 ± 0.022

5.493 ± 0.031

5.989 ± 0.063

3.646 ± 0.032

7.817 ± 0.088

2.201 ± 0.028

5.502 ± 0.045

4.655 ± 0.053

9.615 ± 0.055

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.641 ± 0.024

3.615 ± 0.058

5.096 ± 0.054

3.549 ± 0.032

5.991 ± 0.067

6.126 ± 0.053

5.747 ± 0.084

6.31 ± 0.057

1.512 ± 0.019

3.113 ± 0.03

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski