Human papillomavirus type 90

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Alphapapillomavirus; Alphapapillomavirus 14

Average proteome isoelectric point is 6.34

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q8JNA1|Q8JNA1_9PAPI Protein E6 OS=Human papillomavirus type 90 OX=333769 GN=E6 PE=3 SV=1
MM1 pKa = 7.36HH2 pKa = 7.25GQRR5 pKa = 11.84PTLKK9 pKa = 10.66DD10 pKa = 2.77IFLEE14 pKa = 4.13LDD16 pKa = 3.12QPDD19 pKa = 4.54AVDD22 pKa = 3.44LHH24 pKa = 7.81CNEE27 pKa = 4.22QLASSEE33 pKa = 4.3EE34 pKa = 3.9EE35 pKa = 4.1DD36 pKa = 3.41NRR38 pKa = 11.84EE39 pKa = 4.35DD40 pKa = 4.92GEE42 pKa = 4.53QPTQPTEE49 pKa = 4.0PAQQAYY55 pKa = 9.25RR56 pKa = 11.84VVTSCCRR63 pKa = 11.84CCCTVRR69 pKa = 11.84LVVEE73 pKa = 4.5SGHH76 pKa = 8.0AEE78 pKa = 3.38IRR80 pKa = 11.84QLQEE84 pKa = 3.78LLLGALHH91 pKa = 6.82IVCPLCAA98 pKa = 4.46

Molecular weight: 10.94 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|Q8JN98|Q8JN98_9PAPI Regulatory protein E2 OS=Human papillomavirus type 90 OX=333769 GN=E2 PE=3 SV=1
MM1 pKa = 6.76MHH3 pKa = 6.39STPLCLAPRR12 pKa = 11.84TPTKK16 pKa = 10.62NRR18 pKa = 11.84YY19 pKa = 8.44PLLDD23 pKa = 4.38LLTPHH28 pKa = 6.94TPTNPTPPTPPRR40 pKa = 11.84CWAPRR45 pKa = 11.84RR46 pKa = 11.84HH47 pKa = 4.88TCRR50 pKa = 11.84RR51 pKa = 11.84RR52 pKa = 11.84ISVSDD57 pKa = 3.52SDD59 pKa = 3.98TDD61 pKa = 3.42ISIPTPQKK69 pKa = 8.34TGSSGWHH76 pKa = 4.98VTTQGTSVTLTAQSSTGTSVSVTVHH101 pKa = 6.15LL102 pKa = 4.71

Molecular weight: 11.1 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2346

98

646

335.1

37.25

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.82 ± 0.566

2.728 ± 0.713

6.181 ± 0.611

4.945 ± 0.813

3.41 ± 0.541

6.863 ± 0.569

2.515 ± 0.489

3.879 ± 0.426

4.305 ± 0.663

8.696 ± 0.331

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.918 ± 0.349

3.112 ± 0.505

6.991 ± 1.479

4.945 ± 0.58

5.627 ± 0.175

6.991 ± 0.894

8.142 ± 1.316

6.777 ± 0.564

1.662 ± 0.363

3.495 ± 0.42
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski