Amino acid dipepetide frequency for Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia parapsilosis)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.404AlaAla: 4.404 ± 0.062
0.634AlaCys: 0.634 ± 0.017
2.772AlaAsp: 2.772 ± 0.035
3.244AlaGlu: 3.244 ± 0.041
2.308AlaPhe: 2.308 ± 0.03
3.277AlaGly: 3.277 ± 0.049
1.148AlaHis: 1.148 ± 0.021
3.955AlaIle: 3.955 ± 0.042
4.31AlaLys: 4.31 ± 0.049
5.113AlaLeu: 5.113 ± 0.049
1.188AlaMet: 1.188 ± 0.021
3.359AlaAsn: 3.359 ± 0.036
2.617AlaPro: 2.617 ± 0.04
2.335AlaGln: 2.335 ± 0.037
2.375AlaArg: 2.375 ± 0.032
5.391AlaSer: 5.391 ± 0.052
3.997AlaThr: 3.997 ± 0.047
3.273AlaVal: 3.273 ± 0.036
0.49AlaTrp: 0.49 ± 0.014
1.764AlaTyr: 1.764 ± 0.029
0.0AlaXaa: 0.0 ± 0.0
Cys
0.56CysAla: 0.56 ± 0.016
0.237CysCys: 0.237 ± 0.011
0.62CysAsp: 0.62 ± 0.013
0.559CysGlu: 0.559 ± 0.013
0.617CysPhe: 0.617 ± 0.016
0.79CysGly: 0.79 ± 0.022
0.285CysHis: 0.285 ± 0.011
0.802CysIle: 0.802 ± 0.018
0.651CysLys: 0.651 ± 0.016
1.108CysLeu: 1.108 ± 0.02
0.206CysMet: 0.206 ± 0.008
0.546CysAsn: 0.546 ± 0.013
0.447CysPro: 0.447 ± 0.015
0.418CysGln: 0.418 ± 0.013
0.406CysArg: 0.406 ± 0.012
0.823CysSer: 0.823 ± 0.018
0.543CysThr: 0.543 ± 0.015
0.692CysVal: 0.692 ± 0.015
0.147CysTrp: 0.147 ± 0.006
0.396CysTyr: 0.396 ± 0.013
0.0CysXaa: 0.0 ± 0.0
Asp
3.543AspAla: 3.543 ± 0.039
0.588AspCys: 0.588 ± 0.014
5.555AspAsp: 5.555 ± 0.079
5.499AspGlu: 5.499 ± 0.061
2.695AspPhe: 2.695 ± 0.034
3.23AspGly: 3.23 ± 0.049
1.232AspHis: 1.232 ± 0.021
3.719AspIle: 3.719 ± 0.04
3.802AspLys: 3.802 ± 0.046
5.763AspLeu: 5.763 ± 0.048
0.987AspMet: 0.987 ± 0.019
3.02AspAsn: 3.02 ± 0.038
2.444AspPro: 2.444 ± 0.034
2.069AspGln: 2.069 ± 0.026
1.939AspArg: 1.939 ± 0.032
4.643AspSer: 4.643 ± 0.046
2.917AspThr: 2.917 ± 0.033
3.778AspVal: 3.778 ± 0.042
0.617AspTrp: 0.617 ± 0.016
2.277AspTyr: 2.277 ± 0.03
0.0AspXaa: 0.0 ± 0.0
Glu
3.515GluAla: 3.515 ± 0.045
0.581GluCys: 0.581 ± 0.013
4.272GluAsp: 4.272 ± 0.057
6.247GluGlu: 6.247 ± 0.093
2.738GluPhe: 2.738 ± 0.03
2.872GluGly: 2.872 ± 0.036
1.246GluHis: 1.246 ± 0.022
4.074GluIle: 4.074 ± 0.035
4.89GluLys: 4.89 ± 0.057
6.189GluLeu: 6.189 ± 0.06
1.299GluMet: 1.299 ± 0.021
3.617GluAsn: 3.617 ± 0.045
2.334GluPro: 2.334 ± 0.067
2.756GluGln: 2.756 ± 0.037
2.664GluArg: 2.664 ± 0.033
5.326GluSer: 5.326 ± 0.06
3.416GluThr: 3.416 ± 0.039
3.829GluVal: 3.829 ± 0.041
0.588GluTrp: 0.588 ± 0.015
2.316GluTyr: 2.316 ± 0.029
0.0GluXaa: 0.0 ± 0.0
Phe
2.692PheAla: 2.692 ± 0.032
0.508PheCys: 0.508 ± 0.015
2.966PheAsp: 2.966 ± 0.035
2.74PheGlu: 2.74 ± 0.028
1.885PhePhe: 1.885 ± 0.032
2.832PheGly: 2.832 ± 0.048
0.997PheHis: 0.997 ± 0.019
2.903PheIle: 2.903 ± 0.036
3.144PheLys: 3.144 ± 0.034
3.646PheLeu: 3.646 ± 0.04
0.855PheMet: 0.855 ± 0.018
2.693PheAsn: 2.693 ± 0.032
1.725PhePro: 1.725 ± 0.031
1.783PheGln: 1.783 ± 0.024
1.506PheArg: 1.506 ± 0.023
3.137PheSer: 3.137 ± 0.034
2.569PheThr: 2.569 ± 0.037
2.782PheVal: 2.782 ± 0.037
0.526PheTrp: 0.526 ± 0.02
1.543PheTyr: 1.543 ± 0.025
0.0PheXaa: 0.0 ± 0.0
Gly
3.588GlyAla: 3.588 ± 0.053
0.686GlyCys: 0.686 ± 0.017
3.36GlyAsp: 3.36 ± 0.041
3.284GlyGlu: 3.284 ± 0.053
2.598GlyPhe: 2.598 ± 0.036
4.522GlyGly: 4.522 ± 0.078
1.17GlyHis: 1.17 ± 0.022
3.366GlyIle: 3.366 ± 0.044
3.73GlyLys: 3.73 ± 0.044
4.742GlyLeu: 4.742 ± 0.041
0.95GlyMet: 0.95 ± 0.022
3.017GlyAsn: 3.017 ± 0.053
1.698GlyPro: 1.698 ± 0.028
1.883GlyGln: 1.883 ± 0.039
2.089GlyArg: 2.089 ± 0.033
5.003GlySer: 5.003 ± 0.089
2.95GlyThr: 2.95 ± 0.041
3.565GlyVal: 3.565 ± 0.042
0.629GlyTrp: 0.629 ± 0.018
2.031GlyTyr: 2.031 ± 0.034
0.0GlyXaa: 0.0 ± 0.0
His
1.122HisAla: 1.122 ± 0.021
0.266HisCys: 0.266 ± 0.011
1.347HisAsp: 1.347 ± 0.027
1.403HisGlu: 1.403 ± 0.026
1.009HisPhe: 1.009 ± 0.02
1.212HisGly: 1.212 ± 0.023
1.114HisHis: 1.114 ± 0.031
1.349HisIle: 1.349 ± 0.022
1.455HisLys: 1.455 ± 0.022
2.138HisLeu: 2.138 ± 0.028
0.381HisMet: 0.381 ± 0.012
1.313HisAsn: 1.313 ± 0.026
1.204HisPro: 1.204 ± 0.021
1.341HisGln: 1.341 ± 0.026
1.028HisArg: 1.028 ± 0.018
1.894HisSer: 1.894 ± 0.029
1.09HisThr: 1.09 ± 0.019
1.202HisVal: 1.202 ± 0.022
0.232HisTrp: 0.232 ± 0.009
0.865HisTyr: 0.865 ± 0.016
0.0HisXaa: 0.0 ± 0.0
Ile
3.893IleAla: 3.893 ± 0.043
0.753IleCys: 0.753 ± 0.017
4.397IleAsp: 4.397 ± 0.044
4.12IleGlu: 4.12 ± 0.047
2.626IlePhe: 2.626 ± 0.032
3.416IleGly: 3.416 ± 0.041
1.419IleHis: 1.419 ± 0.022
3.931IleIle: 3.931 ± 0.044
4.461IleLys: 4.461 ± 0.048
5.819IleLeu: 5.819 ± 0.055
1.142IleMet: 1.142 ± 0.021
3.805IleAsn: 3.805 ± 0.038
3.131IlePro: 3.131 ± 0.037
2.317IleGln: 2.317 ± 0.033
2.48IleArg: 2.48 ± 0.033
5.015IleSer: 5.015 ± 0.047
3.675IleThr: 3.675 ± 0.041
3.944IleVal: 3.944 ± 0.046
0.683IleTrp: 0.683 ± 0.017
2.119IleTyr: 2.119 ± 0.032
0.0IleXaa: 0.0 ± 0.0
Lys
3.588LysAla: 3.588 ± 0.04
0.682LysCys: 0.682 ± 0.019
3.928LysAsp: 3.928 ± 0.044
4.869LysGlu: 4.869 ± 0.059
3.115LysPhe: 3.115 ± 0.037
2.925LysGly: 2.925 ± 0.042
1.67LysHis: 1.67 ± 0.025
4.254LysIle: 4.254 ± 0.048
5.655LysLys: 5.655 ± 0.064
7.368LysLeu: 7.368 ± 0.065
1.335LysMet: 1.335 ± 0.021
3.537LysAsn: 3.537 ± 0.036
3.092LysPro: 3.092 ± 0.039
3.373LysGln: 3.373 ± 0.037
3.737LysArg: 3.737 ± 0.046
6.125LysSer: 6.125 ± 0.061
3.644LysThr: 3.644 ± 0.045
4.031LysVal: 4.031 ± 0.044
0.725LysTrp: 0.725 ± 0.017
2.678LysTyr: 2.678 ± 0.031
0.0LysXaa: 0.0 ± 0.0
Leu
5.42LeuAla: 5.42 ± 0.047
1.064LeuCys: 1.064 ± 0.022
5.238LeuAsp: 5.238 ± 0.053
5.463LeuGlu: 5.463 ± 0.046
3.81LeuPhe: 3.81 ± 0.047
4.659LeuGly: 4.659 ± 0.046
2.106LeuHis: 2.106 ± 0.029
5.939LeuIle: 5.939 ± 0.053
6.821LeuLys: 6.821 ± 0.055
8.34LeuLeu: 8.34 ± 0.075
1.79LeuMet: 1.79 ± 0.028
5.519LeuAsn: 5.519 ± 0.051
4.359LeuPro: 4.359 ± 0.044
4.215LeuGln: 4.215 ± 0.042
4.043LeuArg: 4.043 ± 0.047
7.991LeuSer: 7.991 ± 0.063
5.135LeuThr: 5.135 ± 0.047
5.432LeuVal: 5.432 ± 0.042
0.807LeuTrp: 0.807 ± 0.02
3.063LeuTyr: 3.063 ± 0.034
0.0LeuXaa: 0.0 ± 0.0
Met
1.19MetAla: 1.19 ± 0.021
0.227MetCys: 0.227 ± 0.009
1.067MetAsp: 1.067 ± 0.018
1.078MetGlu: 1.078 ± 0.018
0.804MetPhe: 0.804 ± 0.019
1.054MetGly: 1.054 ± 0.021
0.336MetHis: 0.336 ± 0.011
1.177MetIle: 1.177 ± 0.022
1.369MetLys: 1.369 ± 0.022
1.557MetLeu: 1.557 ± 0.026
0.473MetMet: 0.473 ± 0.013
1.105MetAsn: 1.105 ± 0.021
0.745MetPro: 0.745 ± 0.019
0.751MetGln: 0.751 ± 0.016
0.775MetArg: 0.775 ± 0.017
2.009MetSer: 2.009 ± 0.028
1.086MetThr: 1.086 ± 0.019
1.039MetVal: 1.039 ± 0.022
0.159MetTrp: 0.159 ± 0.008
0.605MetTyr: 0.605 ± 0.015
0.0MetXaa: 0.0 ± 0.0
Asn
3.187AsnAla: 3.187 ± 0.037
0.583AsnCys: 0.583 ± 0.015
3.809AsnAsp: 3.809 ± 0.039
3.954AsnGlu: 3.954 ± 0.045
2.465AsnPhe: 2.465 ± 0.031
3.646AsnGly: 3.646 ± 0.073
1.362AsnHis: 1.362 ± 0.023
3.256AsnIle: 3.256 ± 0.034
3.883AsnLys: 3.883 ± 0.041
5.276AsnLeu: 5.276 ± 0.056
0.958AsnMet: 0.958 ± 0.02
3.897AsnAsn: 3.897 ± 0.062
2.535AsnPro: 2.535 ± 0.039
2.395AsnGln: 2.395 ± 0.03
2.079AsnArg: 2.079 ± 0.027
4.839AsnSer: 4.839 ± 0.053
3.135AsnThr: 3.135 ± 0.042
3.218AsnVal: 3.218 ± 0.034
0.657AsnTrp: 0.657 ± 0.016
2.182AsnTyr: 2.182 ± 0.024
0.0AsnXaa: 0.0 ± 0.0
Pro
2.365ProAla: 2.365 ± 0.036
0.322ProCys: 0.322 ± 0.01
2.125ProAsp: 2.125 ± 0.027
2.786ProGlu: 2.786 ± 0.033
1.877ProPhe: 1.877 ± 0.027
2.062ProGly: 2.062 ± 0.037
1.114ProHis: 1.114 ± 0.021
2.916ProIle: 2.916 ± 0.035
3.018ProLys: 3.018 ± 0.035
3.722ProLeu: 3.722 ± 0.041
0.798ProMet: 0.798 ± 0.018
2.515ProAsn: 2.515 ± 0.034
3.219ProPro: 3.219 ± 0.089
2.583ProGln: 2.583 ± 0.047
1.792ProArg: 1.792 ± 0.028
4.429ProSer: 4.429 ± 0.072
3.199ProThr: 3.199 ± 0.074
2.715ProVal: 2.715 ± 0.03
0.386ProTrp: 0.386 ± 0.013
1.43ProTyr: 1.43 ± 0.024
0.0ProXaa: 0.0 ± 0.0
Gln
2.323GlnAla: 2.323 ± 0.034
0.423GlnCys: 0.423 ± 0.013
2.156GlnAsp: 2.156 ± 0.027
2.743GlnGlu: 2.743 ± 0.034
2.019GlnPhe: 2.019 ± 0.031
1.927GlnGly: 1.927 ± 0.033
1.331GlnHis: 1.331 ± 0.026
2.525GlnIle: 2.525 ± 0.031
2.582GlnLys: 2.582 ± 0.034
4.4GlnLeu: 4.4 ± 0.048
0.847GlnMet: 0.847 ± 0.017
2.218GlnAsn: 2.218 ± 0.029
2.305GlnPro: 2.305 ± 0.047
5.579GlnGln: 5.579 ± 0.167
1.96GlnArg: 1.96 ± 0.031
3.951GlnSer: 3.951 ± 0.051
2.149GlnThr: 2.149 ± 0.036
2.437GlnVal: 2.437 ± 0.031
0.39GlnTrp: 0.39 ± 0.011
1.575GlnTyr: 1.575 ± 0.028
0.0GlnXaa: 0.0 ± 0.0
Arg
2.319ArgAla: 2.319 ± 0.033
0.446ArgCys: 0.446 ± 0.012
2.421ArgAsp: 2.421 ± 0.03
2.554ArgGlu: 2.554 ± 0.034
1.866ArgPhe: 1.866 ± 0.026
2.194ArgGly: 2.194 ± 0.038
1.0ArgHis: 1.0 ± 0.018
2.59ArgIle: 2.59 ± 0.034
3.375ArgLys: 3.375 ± 0.04
3.837ArgLeu: 3.837 ± 0.043
0.791ArgMet: 0.791 ± 0.017
2.383ArgAsn: 2.383 ± 0.034
1.572ArgPro: 1.572 ± 0.027
1.881ArgGln: 1.881 ± 0.028
2.469ArgArg: 2.469 ± 0.041
3.499ArgSer: 3.499 ± 0.042
2.036ArgThr: 2.036 ± 0.032
2.326ArgVal: 2.326 ± 0.03
0.419ArgTrp: 0.419 ± 0.011
1.459ArgTyr: 1.459 ± 0.023
0.0ArgXaa: 0.0 ± 0.0
Ser
4.656SerAla: 4.656 ± 0.047
0.818SerCys: 0.818 ± 0.018
4.614SerAsp: 4.614 ± 0.048
4.632SerGlu: 4.632 ± 0.071
3.732SerPhe: 3.732 ± 0.046
4.909SerGly: 4.909 ± 0.078
2.013SerHis: 2.013 ± 0.029
5.922SerIle: 5.922 ± 0.055
6.132SerLys: 6.132 ± 0.059
7.683SerLeu: 7.683 ± 0.058
1.593SerMet: 1.593 ± 0.027
5.384SerAsn: 5.384 ± 0.055
4.158SerPro: 4.158 ± 0.062
3.974SerGln: 3.974 ± 0.046
3.71SerArg: 3.71 ± 0.044
11.114SerSer: 11.114 ± 0.167
6.303SerThr: 6.303 ± 0.077
4.71SerVal: 4.71 ± 0.04
0.812SerTrp: 0.812 ± 0.017
2.668SerTyr: 2.668 ± 0.037
0.0SerXaa: 0.0 ± 0.0
Thr
3.391ThrAla: 3.391 ± 0.037
0.634ThrCys: 0.634 ± 0.017
2.898ThrAsp: 2.898 ± 0.049
3.039ThrGlu: 3.039 ± 0.042
2.444ThrPhe: 2.444 ± 0.037
3.431ThrGly: 3.431 ± 0.092
1.165ThrHis: 1.165 ± 0.026
3.948ThrIle: 3.948 ± 0.04
4.044ThrLys: 4.044 ± 0.04
4.837ThrLeu: 4.837 ± 0.044
1.026ThrMet: 1.026 ± 0.02
3.484ThrAsn: 3.484 ± 0.036
3.306ThrPro: 3.306 ± 0.042
2.165ThrGln: 2.165 ± 0.033
2.316ThrArg: 2.316 ± 0.03
5.939ThrSer: 5.939 ± 0.069
5.165ThrThr: 5.165 ± 0.111
3.182ThrVal: 3.182 ± 0.047
0.585ThrTrp: 0.585 ± 0.02
1.734ThrTyr: 1.734 ± 0.026
0.0ThrXaa: 0.0 ± 0.0
Val
3.8ValAla: 3.8 ± 0.042
0.702ValCys: 0.702 ± 0.016
3.888ValAsp: 3.888 ± 0.037
4.002ValGlu: 4.002 ± 0.043
2.577ValPhe: 2.577 ± 0.035
3.347ValGly: 3.347 ± 0.038
1.196ValHis: 1.196 ± 0.022
3.638ValIle: 3.638 ± 0.042
3.975ValLys: 3.975 ± 0.046
5.315ValLeu: 5.315 ± 0.042
1.141ValMet: 1.141 ± 0.021
3.16ValAsn: 3.16 ± 0.033
2.755ValPro: 2.755 ± 0.034
2.086ValGln: 2.086 ± 0.03
2.203ValArg: 2.203 ± 0.027
4.952ValSer: 4.952 ± 0.042
3.323ValThr: 3.323 ± 0.04
4.091ValVal: 4.091 ± 0.043
0.593ValTrp: 0.593 ± 0.015
2.002ValTyr: 2.002 ± 0.026
0.0ValXaa: 0.0 ± 0.0
Trp
0.525TrpAla: 0.525 ± 0.014
0.201TrpCys: 0.201 ± 0.008
0.601TrpAsp: 0.601 ± 0.017
0.52TrpGlu: 0.52 ± 0.014
0.553TrpPhe: 0.553 ± 0.015
0.573TrpGly: 0.573 ± 0.015
0.206TrpHis: 0.206 ± 0.009
0.673TrpIle: 0.673 ± 0.016
0.743TrpLys: 0.743 ± 0.019
0.972TrpLeu: 0.972 ± 0.021
0.206TrpMet: 0.206 ± 0.008
0.596TrpAsn: 0.596 ± 0.015
0.304TrpPro: 0.304 ± 0.011
0.362TrpGln: 0.362 ± 0.011
0.482TrpArg: 0.482 ± 0.013
0.822TrpSer: 0.822 ± 0.019
0.563TrpThr: 0.563 ± 0.023
0.575TrpVal: 0.575 ± 0.014
0.164TrpTrp: 0.164 ± 0.009
0.377TrpTyr: 0.377 ± 0.013
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.871TyrAla: 1.871 ± 0.03
0.501TyrCys: 0.501 ± 0.014
2.283TyrAsp: 2.283 ± 0.028
2.031TyrGlu: 2.031 ± 0.033
1.695TyrPhe: 1.695 ± 0.027
1.981TyrGly: 1.981 ± 0.033
0.858TyrHis: 0.858 ± 0.018
2.211TyrIle: 2.211 ± 0.031
2.292TyrLys: 2.292 ± 0.033
3.387TyrLeu: 3.387 ± 0.038
0.645TyrMet: 0.645 ± 0.015
2.149TyrAsn: 2.149 ± 0.033
1.423TyrPro: 1.423 ± 0.025
1.571TyrGln: 1.571 ± 0.026
1.384TyrArg: 1.384 ± 0.024
2.632TyrSer: 2.632 ± 0.034
1.838TyrThr: 1.838 ± 0.029
1.927TyrVal: 1.927 ± 0.025
0.406TyrTrp: 0.406 ± 0.012
1.461TyrTyr: 1.461 ± 0.026
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5777 proteins (2913513 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski