Simian immunodeficiency virus (isolate TAN1) (SIV-cpz) (Chimpanzee immunodeficiency virus)

Taxonomy: Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus; Simian immunodeficiency virus; Simian immunodeficiency virus - cpz

Average proteome isoelectric point is 7.39

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 9 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|Q8AIH5|ENV_SIVTN Envelope glycoprotein gp160 OS=Simian immunodeficiency virus (isolate TAN1) OX=388910 PE=3 SV=1
MM1 pKa = 7.42GNIFGRR7 pKa = 11.84WPGARR12 pKa = 11.84KK13 pKa = 9.84AIEE16 pKa = 4.53DD17 pKa = 3.54LHH19 pKa = 5.83NTSSEE24 pKa = 4.2PVGQASQDD32 pKa = 3.71LQNKK36 pKa = 9.46GGLTTNTLGTSADD49 pKa = 3.63VLEE52 pKa = 4.68YY53 pKa = 10.85SADD56 pKa = 3.53HH57 pKa = 6.39TEE59 pKa = 4.24EE60 pKa = 4.03EE61 pKa = 4.3VGFPVRR67 pKa = 11.84PAVPMRR73 pKa = 11.84PMTEE77 pKa = 3.6KK78 pKa = 10.9LAIDD82 pKa = 4.17LSWFLKK88 pKa = 10.56EE89 pKa = 4.98KK90 pKa = 10.83GGLDD94 pKa = 3.53GLFFSPKK101 pKa = 9.16RR102 pKa = 11.84AAILDD107 pKa = 3.27TWMYY111 pKa = 7.97NTQGVFPDD119 pKa = 3.52WQNYY123 pKa = 6.27TPGPGIRR130 pKa = 11.84YY131 pKa = 6.31PLCRR135 pKa = 11.84GWLFKK140 pKa = 10.51LVPVDD145 pKa = 4.21PPEE148 pKa = 5.57DD149 pKa = 3.65DD150 pKa = 3.69EE151 pKa = 6.28KK152 pKa = 11.7NILLHH157 pKa = 6.17PACSHH162 pKa = 5.89GTTDD166 pKa = 4.29PDD168 pKa = 4.01GEE170 pKa = 4.35TLIWRR175 pKa = 11.84FDD177 pKa = 3.12SSLARR182 pKa = 11.84RR183 pKa = 11.84HH184 pKa = 5.57IARR187 pKa = 11.84EE188 pKa = 3.73RR189 pKa = 11.84YY190 pKa = 9.02PEE192 pKa = 3.96YY193 pKa = 10.8FKK195 pKa = 11.43

Molecular weight: 22.01 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|Q8AII1|POL_SIVTN Gag-Pol polyprotein OS=Simian immunodeficiency virus (isolate TAN1) OX=388910 GN=gag-pol PE=3 SV=4
MM1 pKa = 7.37EE2 pKa = 5.44NRR4 pKa = 11.84WQVQVVWMIDD14 pKa = 3.18RR15 pKa = 11.84MRR17 pKa = 11.84LRR19 pKa = 11.84TWTSLVKK26 pKa = 10.14HH27 pKa = 6.62HH28 pKa = 7.12IFTTKK33 pKa = 10.04CCKK36 pKa = 8.91DD37 pKa = 2.85WKK39 pKa = 10.1YY40 pKa = 10.01RR41 pKa = 11.84HH42 pKa = 6.56HH43 pKa = 7.26YY44 pKa = 7.8EE45 pKa = 3.47TDD47 pKa = 3.08TPKK50 pKa = 10.6RR51 pKa = 11.84AGEE54 pKa = 3.56IHH56 pKa = 6.61IPLTEE61 pKa = 3.94RR62 pKa = 11.84SKK64 pKa = 11.31LVVLHH69 pKa = 5.82YY70 pKa = 10.09WGLACGEE77 pKa = 4.38RR78 pKa = 11.84PWHH81 pKa = 6.25LGHH84 pKa = 7.63GIGLEE89 pKa = 3.94WRR91 pKa = 11.84QGKK94 pKa = 10.0YY95 pKa = 7.57STQIDD100 pKa = 4.69PEE102 pKa = 4.29TADD105 pKa = 3.39QLIHH109 pKa = 5.82TRR111 pKa = 11.84YY112 pKa = 6.72FTCFAAGAVRR122 pKa = 11.84QAILGEE128 pKa = 4.42RR129 pKa = 11.84ILTFCHH135 pKa = 5.86FQSGHH140 pKa = 5.15RR141 pKa = 11.84QVGTLQFLAFRR152 pKa = 11.84KK153 pKa = 9.83VVEE156 pKa = 4.56SQDD159 pKa = 3.7KK160 pKa = 9.68QPKK163 pKa = 8.73GPRR166 pKa = 11.84RR167 pKa = 11.84PLPSVTKK174 pKa = 9.59LTEE177 pKa = 4.22DD178 pKa = 2.74RR179 pKa = 11.84WNKK182 pKa = 9.53HH183 pKa = 3.62RR184 pKa = 11.84TTTGRR189 pKa = 11.84RR190 pKa = 11.84EE191 pKa = 3.63NHH193 pKa = 5.95TLSGCC198 pKa = 3.61

Molecular weight: 23.38 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

9

0

9

3657

83

1462

406.3

45.81

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.289 ± 0.428

2.024 ± 0.295

4.02 ± 0.36

6.317 ± 0.518

2.707 ± 0.357

7.711 ± 0.635

2.352 ± 0.447

6.563 ± 0.703

6.153 ± 0.9

8.094 ± 0.492

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.996 ± 0.285

5.004 ± 0.723

5.496 ± 0.599

5.961 ± 0.312

5.688 ± 0.798

5.141 ± 0.731

6.836 ± 0.535

6.125 ± 0.407

2.707 ± 0.291

2.817 ± 0.33
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski