Amino acid dipepetide frequency for Tulasnella calospora MUT 4182

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.643AlaAla: 8.643 ± 0.06	1.025AlaCys: 1.025 ± 0.013	3.949AlaAsp: 3.949 ± 0.027	5.128AlaGlu: 5.128 ± 0.037	3.229AlaPhe: 3.229 ± 0.023	5.355AlaGly: 5.355 ± 0.033	1.811AlaHis: 1.811 ± 0.018	4.237AlaIle: 4.237 ± 0.028	4.041AlaLys: 4.041 ± 0.034	8.426AlaLeu: 8.426 ± 0.046	1.824AlaMet: 1.824 ± 0.016	2.949AlaAsn: 2.949 ± 0.025	5.265AlaPro: 5.265 ± 0.041	3.411AlaGln: 3.411 ± 0.029	5.191AlaArg: 5.191 ± 0.034	7.686AlaSer: 7.686 ± 0.038	5.345AlaThr: 5.345 ± 0.034	5.277AlaVal: 5.277 ± 0.03	1.267AlaTrp: 1.267 ± 0.014	2.089AlaTyr: 2.089 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	0.905CysAla: 0.905 ± 0.011	0.284CysCys: 0.284 ± 0.007	0.694CysAsp: 0.694 ± 0.009	0.567CysGlu: 0.567 ± 0.008	0.539CysPhe: 0.539 ± 0.013	0.923CysGly: 0.923 ± 0.014	0.412CysHis: 0.412 ± 0.007	0.645CysIle: 0.645 ± 0.01	0.54CysLys: 0.54 ± 0.009	1.309CysLeu: 1.309 ± 0.016	0.265CysMet: 0.265 ± 0.006	0.443CysAsn: 0.443 ± 0.009	0.821CysPro: 0.821 ± 0.013	0.493CysGln: 0.493 ± 0.009	0.865CysArg: 0.865 ± 0.014	1.013CysSer: 1.013 ± 0.014	0.714CysThr: 0.714 ± 0.011	0.741CysVal: 0.741 ± 0.012	0.37CysTrp: 0.37 ± 0.008	0.339CysTyr: 0.339 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	4.562AspAla: 4.562 ± 0.03	0.678AspCys: 0.678 ± 0.011	4.041AspAsp: 4.041 ± 0.032	4.22AspGlu: 4.22 ± 0.035	2.157AspPhe: 2.157 ± 0.018	4.029AspGly: 4.029 ± 0.032	1.218AspHis: 1.218 ± 0.014	2.944AspIle: 2.944 ± 0.023	1.999AspLys: 1.999 ± 0.021	5.151AspLeu: 5.151 ± 0.033	1.123AspMet: 1.123 ± 0.013	1.576AspAsn: 1.576 ± 0.015	3.539AspPro: 3.539 ± 0.027	1.842AspGln: 1.842 ± 0.016	2.905AspArg: 2.905 ± 0.024	3.95AspSer: 3.95 ± 0.024	2.661AspThr: 2.661 ± 0.021	3.851AspVal: 3.851 ± 0.025	0.921AspTrp: 0.921 ± 0.013	1.43AspTyr: 1.43 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	5.598GluAla: 5.598 ± 0.046	0.711GluCys: 0.711 ± 0.01	4.048GluAsp: 4.048 ± 0.032	5.301GluGlu: 5.301 ± 0.042	1.883GluPhe: 1.883 ± 0.017	3.876GluGly: 3.876 ± 0.025	1.251GluHis: 1.251 ± 0.013	3.044GluIle: 3.044 ± 0.025	3.05GluLys: 3.05 ± 0.023	5.311GluLeu: 5.311 ± 0.031	1.321GluMet: 1.321 ± 0.015	1.992GluAsn: 1.992 ± 0.018	2.882GluPro: 2.882 ± 0.021	2.079GluGln: 2.079 ± 0.017	3.948GluArg: 3.948 ± 0.029	4.081GluSer: 4.081 ± 0.028	3.189GluThr: 3.189 ± 0.021	3.796GluVal: 3.796 ± 0.025	0.947GluTrp: 0.947 ± 0.011	1.608GluTyr: 1.608 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	2.953PheAla: 2.953 ± 0.024	0.521PheCys: 0.521 ± 0.01	2.209PheAsp: 2.209 ± 0.017	2.014PheGlu: 2.014 ± 0.019	1.401PhePhe: 1.401 ± 0.017	2.829PheGly: 2.829 ± 0.023	0.913PheHis: 0.913 ± 0.011	1.765PheIle: 1.765 ± 0.017	1.601PheLys: 1.601 ± 0.016	3.343PheLeu: 3.343 ± 0.027	0.706PheMet: 0.706 ± 0.01	1.354PheAsn: 1.354 ± 0.015	2.043PhePro: 2.043 ± 0.018	1.325PheGln: 1.325 ± 0.016	1.957PheArg: 1.957 ± 0.018	3.062PheSer: 3.062 ± 0.026	2.096PheThr: 2.096 ± 0.02	2.434PheVal: 2.434 ± 0.018	0.611PheTrp: 0.611 ± 0.01	0.998PheTyr: 0.998 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	5.037GlyAla: 5.037 ± 0.035	0.819GlyCys: 0.819 ± 0.012	3.868GlyAsp: 3.868 ± 0.031	3.712GlyGlu: 3.712 ± 0.027	2.602GlyPhe: 2.602 ± 0.022	5.675GlyGly: 5.675 ± 0.052	1.633GlyHis: 1.633 ± 0.017	3.098GlyIle: 3.098 ± 0.025	3.42GlyLys: 3.42 ± 0.026	6.153GlyLeu: 6.153 ± 0.035	1.476GlyMet: 1.476 ± 0.017	2.564GlyAsn: 2.564 ± 0.022	3.568GlyPro: 3.568 ± 0.03	2.463GlyGln: 2.463 ± 0.022	4.234GlyArg: 4.234 ± 0.027	5.898GlySer: 5.898 ± 0.032	3.972GlyThr: 3.972 ± 0.029	4.158GlyVal: 4.158 ± 0.03	1.213GlyTrp: 1.213 ± 0.012	1.877GlyTyr: 1.877 ± 0.02	0.0GlyXaa: 0.0 ± 0.0
His	1.82HisAla: 1.82 ± 0.017	0.361HisCys: 0.361 ± 0.008	1.181HisAsp: 1.181 ± 0.014	1.231HisGlu: 1.231 ± 0.014	0.901HisPhe: 0.901 ± 0.011	1.676HisGly: 1.676 ± 0.016	0.886HisHis: 0.886 ± 0.016	1.204HisIle: 1.204 ± 0.013	0.798HisLys: 0.798 ± 0.012	2.465HisLeu: 2.465 ± 0.021	0.397HisMet: 0.397 ± 0.008	0.735HisAsn: 0.735 ± 0.01	1.923HisPro: 1.923 ± 0.02	1.013HisGln: 1.013 ± 0.013	1.633HisArg: 1.633 ± 0.017	2.007HisSer: 2.007 ± 0.019	1.233HisThr: 1.233 ± 0.015	1.429HisVal: 1.429 ± 0.016	0.371HisTrp: 0.371 ± 0.007	0.659HisTyr: 0.659 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	3.892IleAla: 3.892 ± 0.029	0.815IleCys: 0.815 ± 0.01	2.609IleAsp: 2.609 ± 0.021	2.564IleGlu: 2.564 ± 0.021	1.846IlePhe: 1.846 ± 0.018	3.217IleGly: 3.217 ± 0.027	1.246IleHis: 1.246 ± 0.014	2.41IleIle: 2.41 ± 0.023	2.164IleLys: 2.164 ± 0.019	4.561IleLeu: 4.561 ± 0.032	0.906IleMet: 0.906 ± 0.013	1.633IleAsn: 1.633 ± 0.016	3.262IlePro: 3.262 ± 0.024	1.935IleGln: 1.935 ± 0.018	3.134IleArg: 3.134 ± 0.025	3.787IleSer: 3.787 ± 0.025	2.828IleThr: 2.828 ± 0.022	3.055IleVal: 3.055 ± 0.024	0.827IleTrp: 0.827 ± 0.013	1.493IleTyr: 1.493 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	4.455LysAla: 4.455 ± 0.033	0.501LysCys: 0.501 ± 0.01	2.554LysAsp: 2.554 ± 0.019	3.153LysGlu: 3.153 ± 0.026	1.464LysPhe: 1.464 ± 0.015	2.971LysGly: 2.971 ± 0.026	1.031LysHis: 1.031 ± 0.014	2.06LysIle: 2.06 ± 0.021	2.884LysLys: 2.884 ± 0.032	4.103LysLeu: 4.103 ± 0.03	0.911LysMet: 0.911 ± 0.012	1.499LysAsn: 1.499 ± 0.017	2.651LysPro: 2.651 ± 0.024	1.635LysGln: 1.635 ± 0.016	3.265LysArg: 3.265 ± 0.024	3.341LysSer: 3.341 ± 0.028	2.638LysThr: 2.638 ± 0.019	2.703LysVal: 2.703 ± 0.021	0.697LysTrp: 0.697 ± 0.01	1.314LysTyr: 1.314 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	8.035LeuAla: 8.035 ± 0.038	1.348LeuCys: 1.348 ± 0.017	5.111LeuAsp: 5.111 ± 0.032	5.786LeuGlu: 5.786 ± 0.036	3.216LeuPhe: 3.216 ± 0.026	6.423LeuGly: 6.423 ± 0.043	2.427LeuHis: 2.427 ± 0.02	3.893LeuIle: 3.893 ± 0.026	4.435LeuLys: 4.435 ± 0.03	8.507LeuLeu: 8.507 ± 0.05	1.727LeuMet: 1.727 ± 0.017	3.115LeuAsn: 3.115 ± 0.021	6.274LeuPro: 6.274 ± 0.036	3.843LeuGln: 3.843 ± 0.03	6.243LeuArg: 6.243 ± 0.038	7.643LeuSer: 7.643 ± 0.04	5.106LeuThr: 5.106 ± 0.029	5.767LeuVal: 5.767 ± 0.035	1.449LeuTrp: 1.449 ± 0.019	2.402LeuTyr: 2.402 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	1.916MetAla: 1.916 ± 0.018	0.21MetCys: 0.21 ± 0.005	1.204MetAsp: 1.204 ± 0.015	1.305MetGlu: 1.305 ± 0.015	0.637MetPhe: 0.637 ± 0.01	1.288MetGly: 1.288 ± 0.017	0.447MetHis: 0.447 ± 0.009	0.9MetIle: 0.9 ± 0.013	0.972MetLys: 0.972 ± 0.013	1.664MetLeu: 1.664 ± 0.017	0.512MetMet: 0.512 ± 0.01	0.691MetAsn: 0.691 ± 0.011	1.178MetPro: 1.178 ± 0.013	0.77MetGln: 0.77 ± 0.011	1.189MetArg: 1.189 ± 0.014	1.84MetSer: 1.84 ± 0.018	1.311MetThr: 1.311 ± 0.014	1.195MetVal: 1.195 ± 0.015	0.269MetTrp: 0.269 ± 0.006	0.503MetTyr: 0.503 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.101AsnAla: 3.101 ± 0.024	0.438AsnCys: 0.438 ± 0.009	1.879AsnAsp: 1.879 ± 0.019	1.87AsnGlu: 1.87 ± 0.019	1.189AsnPhe: 1.189 ± 0.015	2.669AsnGly: 2.669 ± 0.025	0.806AsnHis: 0.806 ± 0.01	1.904AsnIle: 1.904 ± 0.018	1.297AsnLys: 1.297 ± 0.016	3.267AsnLeu: 3.267 ± 0.022	0.663AsnMet: 0.663 ± 0.011	1.24AsnAsn: 1.24 ± 0.014	2.556AsnPro: 2.556 ± 0.022	1.314AsnGln: 1.314 ± 0.016	1.876AsnArg: 1.876 ± 0.017	2.695AsnSer: 2.695 ± 0.021	2.015AsnThr: 2.015 ± 0.018	2.364AsnVal: 2.364 ± 0.019	0.538AsnTrp: 0.538 ± 0.009	0.935AsnTyr: 0.935 ± 0.011	0.0AsnXaa: 0.0 ± 0.0
Pro	5.517ProAla: 5.517 ± 0.038	0.574ProCys: 0.574 ± 0.01	3.175ProAsp: 3.175 ± 0.023	3.851ProGlu: 3.851 ± 0.027	2.233ProPhe: 2.233 ± 0.02	3.935ProGly: 3.935 ± 0.035	1.497ProHis: 1.497 ± 0.017	2.777ProIle: 2.777 ± 0.018	2.746ProLys: 2.746 ± 0.024	5.401ProLeu: 5.401 ± 0.033	1.101ProMet: 1.101 ± 0.013	2.513ProAsn: 2.513 ± 0.02	6.645ProPro: 6.645 ± 0.077	2.604ProGln: 2.604 ± 0.021	3.603ProArg: 3.603 ± 0.027	7.336ProSer: 7.336 ± 0.048	4.669ProThr: 4.669 ± 0.034	3.646ProVal: 3.646 ± 0.027	0.845ProTrp: 0.845 ± 0.013	1.49ProTyr: 1.49 ± 0.016	0.0ProXaa: 0.0 ± 0.0
Gln	3.708GlnAla: 3.708 ± 0.034	0.468GlnCys: 0.468 ± 0.009	1.9GlnAsp: 1.9 ± 0.018	2.226GlnGlu: 2.226 ± 0.022	1.192GlnPhe: 1.192 ± 0.013	2.353GlnGly: 2.353 ± 0.021	0.988GlnHis: 0.988 ± 0.013	1.802GlnIle: 1.802 ± 0.018	1.594GlnLys: 1.594 ± 0.017	3.597GlnLeu: 3.597 ± 0.024	0.76GlnMet: 0.76 ± 0.01	1.345GlnAsn: 1.345 ± 0.016	2.672GlnPro: 2.672 ± 0.027	2.074GlnGln: 2.074 ± 0.04	2.484GlnArg: 2.484 ± 0.023	3.1GlnSer: 3.1 ± 0.029	2.262GlnThr: 2.262 ± 0.018	2.28GlnVal: 2.28 ± 0.018	0.589GlnTrp: 0.589 ± 0.009	1.047GlnTyr: 1.047 ± 0.012	0.0GlnXaa: 0.0 ± 0.0
Arg	4.992ArgAla: 4.992 ± 0.032	0.841ArgCys: 0.841 ± 0.012	3.155ArgAsp: 3.155 ± 0.025	3.579ArgGlu: 3.579 ± 0.028	2.261ArgPhe: 2.261 ± 0.021	3.706ArgGly: 3.706 ± 0.027	1.57ArgHis: 1.57 ± 0.016	3.272ArgIle: 3.272 ± 0.026	3.206ArgLys: 3.206 ± 0.025	6.079ArgLeu: 6.079 ± 0.035	1.38ArgMet: 1.38 ± 0.015	2.163ArgAsn: 2.163 ± 0.019	3.78ArgPro: 3.78 ± 0.028	2.43ArgGln: 2.43 ± 0.024	5.022ArgArg: 5.022 ± 0.041	5.192ArgSer: 5.192 ± 0.038	3.503ArgThr: 3.503 ± 0.026	3.501ArgVal: 3.501 ± 0.023	1.167ArgTrp: 1.167 ± 0.014	1.64ArgTyr: 1.64 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	7.022SerAla: 7.022 ± 0.036	0.956SerCys: 0.956 ± 0.013	4.282SerAsp: 4.282 ± 0.026	4.245SerGlu: 4.245 ± 0.027	3.129SerPhe: 3.129 ± 0.02	5.72SerGly: 5.72 ± 0.035	1.952SerHis: 1.952 ± 0.017	3.961SerIle: 3.961 ± 0.028	3.818SerLys: 3.818 ± 0.026	7.921SerLeu: 7.921 ± 0.038	1.603SerMet: 1.603 ± 0.015	2.997SerAsn: 2.997 ± 0.025	6.366SerPro: 6.366 ± 0.048	3.242SerGln: 3.242 ± 0.026	5.226SerArg: 5.226 ± 0.037	9.78SerSer: 9.78 ± 0.074	6.147SerThr: 6.147 ± 0.04	4.731SerVal: 4.731 ± 0.029	1.149SerTrp: 1.149 ± 0.014	2.07SerTyr: 2.07 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	5.211ThrAla: 5.211 ± 0.034	0.796ThrCys: 0.796 ± 0.01	2.766ThrAsp: 2.766 ± 0.023	2.908ThrGlu: 2.908 ± 0.02	2.357ThrPhe: 2.357 ± 0.019	4.071ThrGly: 4.071 ± 0.031	1.272ThrHis: 1.272 ± 0.013	3.083ThrIle: 3.083 ± 0.023	2.468ThrLys: 2.468 ± 0.023	5.748ThrLeu: 5.748 ± 0.031	1.119ThrMet: 1.119 ± 0.015	2.046ThrAsn: 2.046 ± 0.018	4.659ThrPro: 4.659 ± 0.037	2.057ThrGln: 2.057 ± 0.019	3.364ThrArg: 3.364 ± 0.023	5.849ThrSer: 5.849 ± 0.038	4.641ThrThr: 4.641 ± 0.053	3.663ThrVal: 3.663 ± 0.025	0.875ThrTrp: 0.875 ± 0.012	1.503ThrTyr: 1.503 ± 0.014	0.0ThrXaa: 0.0 ± 0.0
Val	5.334ValAla: 5.334 ± 0.032	0.88ValCys: 0.88 ± 0.012	3.593ValAsp: 3.593 ± 0.022	3.838ValGlu: 3.838 ± 0.025	2.284ValPhe: 2.284 ± 0.019	3.936ValGly: 3.936 ± 0.031	1.491ValHis: 1.491 ± 0.018	2.989ValIle: 2.989 ± 0.022	2.94ValLys: 2.94 ± 0.021	5.731ValLeu: 5.731 ± 0.036	1.232ValMet: 1.232 ± 0.016	2.113ValAsn: 2.113 ± 0.019	3.908ValPro: 3.908 ± 0.028	2.417ValGln: 2.417 ± 0.02	3.561ValArg: 3.561 ± 0.025	4.587ValSer: 4.587 ± 0.029	3.454ValThr: 3.454 ± 0.023	4.282ValVal: 4.282 ± 0.03	0.982ValTrp: 0.982 ± 0.014	1.762ValTyr: 1.762 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.314TrpAla: 1.314 ± 0.016	0.241TrpCys: 0.241 ± 0.007	0.982TrpAsp: 0.982 ± 0.017	1.078TrpGlu: 1.078 ± 0.014	0.537TrpPhe: 0.537 ± 0.01	0.926TrpGly: 0.926 ± 0.011	0.358TrpHis: 0.358 ± 0.007	0.866TrpIle: 0.866 ± 0.012	0.886TrpLys: 0.886 ± 0.011	1.404TrpLeu: 1.404 ± 0.015	0.442TrpMet: 0.442 ± 0.007	0.685TrpAsn: 0.685 ± 0.011	0.617TrpPro: 0.617 ± 0.009	0.499TrpGln: 0.499 ± 0.008	1.033TrpArg: 1.033 ± 0.013	1.276TrpSer: 1.276 ± 0.012	1.018TrpThr: 1.018 ± 0.012	0.911TrpVal: 0.911 ± 0.014	0.303TrpTrp: 0.303 ± 0.008	0.432TrpTyr: 0.432 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.133TyrAla: 2.133 ± 0.02	0.414TyrCys: 0.414 ± 0.008	1.594TyrAsp: 1.594 ± 0.02	1.34TyrGlu: 1.34 ± 0.015	1.076TyrPhe: 1.076 ± 0.015	1.862TyrGly: 1.862 ± 0.019	0.716TyrHis: 0.716 ± 0.012	1.33TyrIle: 1.33 ± 0.016	0.971TyrLys: 0.971 ± 0.012	2.611TyrLeu: 2.611 ± 0.023	0.533TyrMet: 0.533 ± 0.01	0.962TyrAsn: 0.962 ± 0.014	1.551TyrPro: 1.551 ± 0.015	0.995TyrGln: 0.995 ± 0.012	1.705TyrArg: 1.705 ± 0.017	2.193TyrSer: 2.193 ± 0.024	1.656TyrThr: 1.656 ± 0.02	1.531TyrVal: 1.531 ± 0.019	0.417TyrTrp: 0.417 ± 0.009	0.865TyrTyr: 0.865 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 19357 proteins (6612335 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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