Human T-cell leukemia virus 2 (HTLV-2)

Taxonomy: Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Ortervirales; Retroviridae; Orthoretrovirinae; Deltaretrovirus; Primate T-lymphotropic virus 2

Average proteome isoelectric point is 7.79

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 6 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|Q85601|REX_HTLV2 Protein Rex OS=Human T-cell leukemia virus 2 OX=11909 PE=1 SV=1
MM1 pKa = 7.36AHH3 pKa = 6.69FPGFGQSLLYY13 pKa = 10.27GYY15 pKa = 9.11PVYY18 pKa = 11.22VFGDD22 pKa = 4.2CVQADD27 pKa = 3.99WCPVSGGLCSTRR39 pKa = 11.84LHH41 pKa = 5.88RR42 pKa = 11.84HH43 pKa = 5.69ALLATCPEE51 pKa = 4.48HH52 pKa = 6.78QLTWDD57 pKa = 4.66PIDD60 pKa = 3.65GRR62 pKa = 11.84VVSSPLQYY70 pKa = 10.73LIPRR74 pKa = 11.84LPSFPTQRR82 pKa = 11.84TSRR85 pKa = 11.84TLKK88 pKa = 10.54VLTPPTTPVSPKK100 pKa = 9.78VPPAFFQSMRR110 pKa = 11.84KK111 pKa = 7.08HH112 pKa = 4.32TPYY115 pKa = 10.76RR116 pKa = 11.84NGCLEE121 pKa = 4.14PTLGDD126 pKa = 3.72QLPSLAFPEE135 pKa = 4.8PGLRR139 pKa = 11.84PQNIYY144 pKa = 7.07TTWGKK149 pKa = 7.71TVVCLYY155 pKa = 10.39LYY157 pKa = 10.27QLSPPMTWPLIPHH170 pKa = 6.93VIFCHH175 pKa = 5.62PRR177 pKa = 11.84QLGAFLTKK185 pKa = 10.45VPLKK189 pKa = 10.45RR190 pKa = 11.84LEE192 pKa = 3.93EE193 pKa = 3.98LLYY196 pKa = 11.36KK197 pKa = 10.06MFLHH201 pKa = 6.72TGTVIVLPEE210 pKa = 5.35DD211 pKa = 4.23DD212 pKa = 5.57LPTTMFQPVRR222 pKa = 11.84APCIQTAWCTGLLPYY237 pKa = 10.38HH238 pKa = 7.13SILTTPGLIWTFNDD252 pKa = 4.12GSPMISGPYY261 pKa = 8.63PKK263 pKa = 10.04AGQPSLVVQSSLLIFEE279 pKa = 4.5KK280 pKa = 10.99FEE282 pKa = 4.23TKK284 pKa = 10.32AFHH287 pKa = 6.74PSYY290 pKa = 10.61LLSHH294 pKa = 6.14QLIQYY299 pKa = 10.46SSFHH303 pKa = 6.03NLHH306 pKa = 6.67LLFDD310 pKa = 4.95EE311 pKa = 4.54YY312 pKa = 11.51TNIPVSILFNKK323 pKa = 9.99EE324 pKa = 3.52EE325 pKa = 4.57ADD327 pKa = 4.3DD328 pKa = 4.67NGDD331 pKa = 3.26

Molecular weight: 37.32 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|Q85601|REX_HTLV2 Protein Rex OS=Human T-cell leukemia virus 2 OX=11909 PE=1 SV=1
MM1 pKa = 7.83PKK3 pKa = 9.05TRR5 pKa = 11.84RR6 pKa = 11.84QRR8 pKa = 11.84TRR10 pKa = 11.84RR11 pKa = 11.84ARR13 pKa = 11.84RR14 pKa = 11.84NRR16 pKa = 11.84PPTPWPISQDD26 pKa = 3.28LDD28 pKa = 3.38RR29 pKa = 11.84ASYY32 pKa = 10.25MDD34 pKa = 3.74TPSTCLAIVYY44 pKa = 9.66RR45 pKa = 11.84PIGVPSQVVYY55 pKa = 10.58VPPAYY60 pKa = 9.14IDD62 pKa = 3.59MPSWPPVQSTNSPGTPSMDD81 pKa = 3.43ALSALLSNTLSLASPPSPPRR101 pKa = 11.84EE102 pKa = 3.81PQGPSRR108 pKa = 11.84SLPLPPLLSPPRR120 pKa = 11.84FHH122 pKa = 7.24LPSFNQCEE130 pKa = 4.46STPPTEE136 pKa = 3.61MDD138 pKa = 2.89AWNQPSGISSPPSPSPNLASVPKK161 pKa = 9.68TSTPPGEE168 pKa = 4.29KK169 pKa = 9.91PP170 pKa = 3.15

Molecular weight: 18.46 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

6

0

6

3483

170

1461

580.5

64.47

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.713 ± 0.374

2.44 ± 0.203

3.474 ± 0.185

3.129 ± 0.288

2.9 ± 0.391

5.197 ± 0.253

3.445 ± 0.49

4.823 ± 0.33

3.704 ± 0.405

12.977 ± 0.589

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.292 ± 0.217

3.56 ± 0.216

12.719 ± 1.157

7.063 ± 0.584

4.45 ± 0.408

7.264 ± 1.049

7.35 ± 0.24

4.077 ± 0.364

1.895 ± 0.159

2.527 ± 0.339
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski