Amino acid dipepetide frequency for Phlebiopsis gigantea 11061_1 CR5-6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.165AlaAla: 10.165 ± 0.069	1.216AlaCys: 1.216 ± 0.015	4.549AlaAsp: 4.549 ± 0.03	5.192AlaGlu: 5.192 ± 0.04	3.428AlaPhe: 3.428 ± 0.029	5.985AlaGly: 5.985 ± 0.042	2.333AlaHis: 2.333 ± 0.023	4.009AlaIle: 4.009 ± 0.033	3.8AlaLys: 3.8 ± 0.034	9.1AlaLeu: 9.1 ± 0.047	2.053AlaMet: 2.053 ± 0.021	2.764AlaAsn: 2.764 ± 0.026	5.78AlaPro: 5.78 ± 0.046	3.701AlaGln: 3.701 ± 0.031	5.982AlaArg: 5.982 ± 0.04	8.056AlaSer: 8.056 ± 0.055	5.672AlaThr: 5.672 ± 0.041	6.169AlaVal: 6.169 ± 0.04	1.296AlaTrp: 1.296 ± 0.017	2.401AlaTyr: 2.401 ± 0.024	0.003AlaXaa: 0.003 ± 0.001
Cys	1.177CysAla: 1.177 ± 0.016	0.261CysCys: 0.261 ± 0.009	0.662CysAsp: 0.662 ± 0.012	0.588CysGlu: 0.588 ± 0.011	0.487CysPhe: 0.487 ± 0.009	1.002CysGly: 1.002 ± 0.016	0.346CysHis: 0.346 ± 0.008	0.667CysIle: 0.667 ± 0.013	0.491CysLys: 0.491 ± 0.009	1.226CysLeu: 1.226 ± 0.017	0.29CysMet: 0.29 ± 0.008	0.401CysAsn: 0.401 ± 0.01	0.785CysPro: 0.785 ± 0.015	0.432CysGln: 0.432 ± 0.012	0.837CysArg: 0.837 ± 0.013	1.026CysSer: 1.026 ± 0.016	0.834CysThr: 0.834 ± 0.014	0.897CysVal: 0.897 ± 0.013	0.206CysTrp: 0.206 ± 0.007	0.346CysTyr: 0.346 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.341AspAla: 5.341 ± 0.034	0.609AspCys: 0.609 ± 0.012	4.205AspAsp: 4.205 ± 0.04	4.285AspGlu: 4.285 ± 0.04	2.057AspPhe: 2.057 ± 0.021	3.956AspGly: 3.956 ± 0.03	1.173AspHis: 1.173 ± 0.015	2.953AspIle: 2.953 ± 0.026	2.069AspLys: 2.069 ± 0.023	4.857AspLeu: 4.857 ± 0.038	1.188AspMet: 1.188 ± 0.014	1.532AspAsn: 1.532 ± 0.02	3.421AspPro: 3.421 ± 0.03	1.544AspGln: 1.544 ± 0.018	2.921AspArg: 2.921 ± 0.032	3.855AspSer: 3.855 ± 0.032	2.999AspThr: 2.999 ± 0.026	4.208AspVal: 4.208 ± 0.031	0.853AspTrp: 0.853 ± 0.015	1.409AspTyr: 1.409 ± 0.018	0.001AspXaa: 0.001 ± 0.001
Glu	5.149GluAla: 5.149 ± 0.038	0.628GluCys: 0.628 ± 0.012	4.172GluAsp: 4.172 ± 0.042	4.898GluGlu: 4.898 ± 0.055	1.801GluPhe: 1.801 ± 0.02	3.592GluGly: 3.592 ± 0.03	1.526GluHis: 1.526 ± 0.02	2.567GluIle: 2.567 ± 0.026	2.881GluLys: 2.881 ± 0.029	5.35GluLeu: 5.35 ± 0.035	1.277GluMet: 1.277 ± 0.017	1.734GluAsn: 1.734 ± 0.019	2.761GluPro: 2.761 ± 0.03	2.26GluGln: 2.26 ± 0.024	4.038GluArg: 4.038 ± 0.037	3.727GluSer: 3.727 ± 0.033	3.061GluThr: 3.061 ± 0.023	3.634GluVal: 3.634 ± 0.032	0.894GluTrp: 0.894 ± 0.014	1.538GluTyr: 1.538 ± 0.017	0.001GluXaa: 0.001 ± 0.0
Phe	3.374PheAla: 3.374 ± 0.032	0.554PheCys: 0.554 ± 0.012	2.238PheAsp: 2.238 ± 0.021	1.954PheGlu: 1.954 ± 0.018	1.525PhePhe: 1.525 ± 0.021	2.685PheGly: 2.685 ± 0.033	0.91PheHis: 0.91 ± 0.015	1.702PheIle: 1.702 ± 0.019	1.439PheLys: 1.439 ± 0.017	3.415PheLeu: 3.415 ± 0.03	0.747PheMet: 0.747 ± 0.012	1.259PheAsn: 1.259 ± 0.016	2.027PhePro: 2.027 ± 0.024	1.168PheGln: 1.168 ± 0.017	1.929PheArg: 1.929 ± 0.02	3.001PheSer: 3.001 ± 0.028	2.25PheThr: 2.25 ± 0.024	2.694PheVal: 2.694 ± 0.028	0.578PheTrp: 0.578 ± 0.012	1.04PheTyr: 1.04 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	5.653GlyAla: 5.653 ± 0.039	0.897GlyCys: 0.897 ± 0.016	3.405GlyAsp: 3.405 ± 0.024	3.476GlyGlu: 3.476 ± 0.029	2.521GlyPhe: 2.521 ± 0.027	5.309GlyGly: 5.309 ± 0.057	1.732GlyHis: 1.732 ± 0.02	3.059GlyIle: 3.059 ± 0.032	3.077GlyLys: 3.077 ± 0.032	5.768GlyLeu: 5.768 ± 0.032	1.443GlyMet: 1.443 ± 0.016	2.059GlyAsn: 2.059 ± 0.024	3.423GlyPro: 3.423 ± 0.028	2.3GlyGln: 2.3 ± 0.026	4.252GlyArg: 4.252 ± 0.033	5.476GlySer: 5.476 ± 0.046	4.038GlyThr: 4.038 ± 0.031	4.418GlyVal: 4.418 ± 0.032	1.133GlyTrp: 1.133 ± 0.013	1.878GlyTyr: 1.878 ± 0.024	0.001GlyXaa: 0.001 ± 0.0
His	2.44HisAla: 2.44 ± 0.025	0.352HisCys: 0.352 ± 0.009	1.379HisAsp: 1.379 ± 0.017	1.347HisGlu: 1.347 ± 0.017	0.955HisPhe: 0.955 ± 0.015	1.714HisGly: 1.714 ± 0.02	0.873HisHis: 0.873 ± 0.016	1.3HisIle: 1.3 ± 0.019	0.894HisLys: 0.894 ± 0.015	2.485HisLeu: 2.485 ± 0.02	0.51HisMet: 0.51 ± 0.012	0.778HisAsn: 0.778 ± 0.014	1.955HisPro: 1.955 ± 0.025	0.847HisGln: 0.847 ± 0.013	1.749HisArg: 1.749 ± 0.02	2.054HisSer: 2.054 ± 0.019	1.594HisThr: 1.594 ± 0.021	1.754HisVal: 1.754 ± 0.02	0.36HisTrp: 0.36 ± 0.009	0.696HisTyr: 0.696 ± 0.013	0.001HisXaa: 0.001 ± 0.0
Ile	4.228IleAla: 4.228 ± 0.03	0.707IleCys: 0.707 ± 0.011	2.516IleAsp: 2.516 ± 0.024	2.432IleGlu: 2.432 ± 0.025	1.771IlePhe: 1.771 ± 0.024	2.858IleGly: 2.858 ± 0.028	1.178IleHis: 1.178 ± 0.016	2.249IleIle: 2.249 ± 0.027	1.777IleLys: 1.777 ± 0.019	4.312IleLeu: 4.312 ± 0.037	0.891IleMet: 0.891 ± 0.014	1.39IleAsn: 1.39 ± 0.017	3.108IlePro: 3.108 ± 0.026	1.642IleGln: 1.642 ± 0.019	2.717IleArg: 2.717 ± 0.025	3.578IleSer: 3.578 ± 0.032	2.644IleThr: 2.644 ± 0.023	3.312IleVal: 3.312 ± 0.031	0.702IleTrp: 0.702 ± 0.013	1.242IleTyr: 1.242 ± 0.017	0.001IleXaa: 0.001 ± 0.0
Lys	3.979LysAla: 3.979 ± 0.036	0.448LysCys: 0.448 ± 0.009	2.378LysAsp: 2.378 ± 0.026	2.798LysGlu: 2.798 ± 0.026	1.3LysPhe: 1.3 ± 0.019	2.614LysGly: 2.614 ± 0.027	1.087LysHis: 1.087 ± 0.016	1.834LysIle: 1.834 ± 0.019	2.665LysLys: 2.665 ± 0.039	3.741LysLeu: 3.741 ± 0.03	0.84LysMet: 0.84 ± 0.013	1.315LysAsn: 1.315 ± 0.018	2.442LysPro: 2.442 ± 0.027	1.572LysGln: 1.572 ± 0.019	3.173LysArg: 3.173 ± 0.03	2.845LysSer: 2.845 ± 0.029	2.509LysThr: 2.509 ± 0.023	2.581LysVal: 2.581 ± 0.025	0.611LysTrp: 0.611 ± 0.013	1.221LysTyr: 1.221 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	8.848LeuAla: 8.848 ± 0.048	1.326LeuCys: 1.326 ± 0.016	5.223LeuAsp: 5.223 ± 0.036	5.344LeuGlu: 5.344 ± 0.042	3.428LeuPhe: 3.428 ± 0.03	5.817LeuGly: 5.817 ± 0.044	2.558LeuHis: 2.558 ± 0.024	3.65LeuIle: 3.65 ± 0.034	3.764LeuLys: 3.764 ± 0.031	8.816LeuLeu: 8.816 ± 0.054	1.692LeuMet: 1.692 ± 0.018	2.903LeuAsn: 2.903 ± 0.026	6.346LeuPro: 6.346 ± 0.042	3.751LeuGln: 3.751 ± 0.031	6.489LeuArg: 6.489 ± 0.043	7.785LeuSer: 7.785 ± 0.049	5.261LeuThr: 5.261 ± 0.035	6.147LeuVal: 6.147 ± 0.042	1.281LeuTrp: 1.281 ± 0.015	2.433LeuTyr: 2.433 ± 0.025	0.001LeuXaa: 0.001 ± 0.0
Met	1.881MetAla: 1.881 ± 0.019	0.254MetCys: 0.254 ± 0.008	1.144MetAsp: 1.144 ± 0.017	1.066MetGlu: 1.066 ± 0.016	0.792MetPhe: 0.792 ± 0.012	1.208MetGly: 1.208 ± 0.017	0.579MetHis: 0.579 ± 0.01	0.869MetIle: 0.869 ± 0.014	0.89MetLys: 0.89 ± 0.013	1.889MetLeu: 1.889 ± 0.021	0.473MetMet: 0.473 ± 0.011	0.711MetAsn: 0.711 ± 0.013	1.297MetPro: 1.297 ± 0.019	0.851MetGln: 0.851 ± 0.012	1.37MetArg: 1.37 ± 0.015	2.004MetSer: 2.004 ± 0.022	1.22MetThr: 1.22 ± 0.016	1.185MetVal: 1.185 ± 0.014	0.274MetTrp: 0.274 ± 0.007	0.554MetTyr: 0.554 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.986AsnAla: 2.986 ± 0.027	0.361AsnCys: 0.361 ± 0.01	1.645AsnAsp: 1.645 ± 0.022	1.57AsnGlu: 1.57 ± 0.019	1.184AsnPhe: 1.184 ± 0.014	2.384AsnGly: 2.384 ± 0.028	0.718AsnHis: 0.718 ± 0.013	1.753AsnIle: 1.753 ± 0.02	1.226AsnLys: 1.226 ± 0.017	2.897AsnLeu: 2.897 ± 0.02	0.71AsnMet: 0.71 ± 0.013	1.056AsnAsn: 1.056 ± 0.017	2.082AsnPro: 2.082 ± 0.023	0.986AsnGln: 0.986 ± 0.017	1.576AsnArg: 1.576 ± 0.018	2.273AsnSer: 2.273 ± 0.022	1.97AsnThr: 1.97 ± 0.023	2.317AsnVal: 2.317 ± 0.022	0.461AsnTrp: 0.461 ± 0.011	0.827AsnTyr: 0.827 ± 0.013	0.001AsnXaa: 0.001 ± 0.001
Pro	6.288ProAla: 6.288 ± 0.047	0.607ProCys: 0.607 ± 0.013	3.226ProAsp: 3.226 ± 0.026	3.673ProGlu: 3.673 ± 0.033	2.142ProPhe: 2.142 ± 0.022	3.962ProGly: 3.962 ± 0.031	1.68ProHis: 1.68 ± 0.02	2.517ProIle: 2.517 ± 0.024	2.296ProLys: 2.296 ± 0.025	5.477ProLeu: 5.477 ± 0.037	1.109ProMet: 1.109 ± 0.016	1.948ProAsn: 1.948 ± 0.022	6.593ProPro: 6.593 ± 0.075	2.476ProGln: 2.476 ± 0.029	4.025ProArg: 4.025 ± 0.035	7.059ProSer: 7.059 ± 0.061	4.555ProThr: 4.555 ± 0.034	4.028ProVal: 4.028 ± 0.032	0.753ProTrp: 0.753 ± 0.015	1.623ProTyr: 1.623 ± 0.018	0.002ProXaa: 0.002 ± 0.001
Gln	3.426GlnAla: 3.426 ± 0.029	0.481GlnCys: 0.481 ± 0.011	1.929GlnAsp: 1.929 ± 0.021	2.125GlnGlu: 2.125 ± 0.022	1.241GlnPhe: 1.241 ± 0.017	2.179GlnGly: 2.179 ± 0.025	1.071GlnHis: 1.071 ± 0.015	1.669GlnIle: 1.669 ± 0.019	1.549GlnLys: 1.549 ± 0.02	3.472GlnLeu: 3.472 ± 0.031	0.795GlnMet: 0.795 ± 0.013	1.212GlnAsn: 1.212 ± 0.017	2.401GlnPro: 2.401 ± 0.027	1.869GlnGln: 1.869 ± 0.037	2.564GlnArg: 2.564 ± 0.024	2.82GlnSer: 2.82 ± 0.028	2.239GlnThr: 2.239 ± 0.022	2.195GlnVal: 2.195 ± 0.019	0.579GlnTrp: 0.579 ± 0.013	1.097GlnTyr: 1.097 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	5.884ArgAla: 5.884 ± 0.038	0.864ArgCys: 0.864 ± 0.016	3.37ArgAsp: 3.37 ± 0.033	3.897ArgGlu: 3.897 ± 0.035	2.211ArgPhe: 2.211 ± 0.022	3.896ArgGly: 3.896 ± 0.031	1.754ArgHis: 1.754 ± 0.02	2.875ArgIle: 2.875 ± 0.024	3.152ArgLys: 3.152 ± 0.027	5.895ArgLeu: 5.895 ± 0.044	1.378ArgMet: 1.378 ± 0.016	1.917ArgAsn: 1.917 ± 0.019	3.961ArgPro: 3.961 ± 0.036	2.394ArgGln: 2.394 ± 0.021	5.772ArgArg: 5.772 ± 0.045	5.148ArgSer: 5.148 ± 0.046	3.884ArgThr: 3.884 ± 0.032	4.014ArgVal: 4.014 ± 0.034	1.019ArgTrp: 1.019 ± 0.015	1.667ArgTyr: 1.667 ± 0.019	0.001ArgXaa: 0.001 ± 0.0
Ser	7.629SerAla: 7.629 ± 0.046	0.978SerCys: 0.978 ± 0.015	4.136SerAsp: 4.136 ± 0.03	3.812SerGlu: 3.812 ± 0.031	2.944SerPhe: 2.944 ± 0.027	5.425SerGly: 5.425 ± 0.044	2.045SerHis: 2.045 ± 0.022	3.634SerIle: 3.634 ± 0.032	3.075SerLys: 3.075 ± 0.028	7.721SerLeu: 7.721 ± 0.047	1.684SerMet: 1.684 ± 0.018	2.475SerAsn: 2.475 ± 0.023	6.29SerPro: 6.29 ± 0.064	3.018SerGln: 3.018 ± 0.028	5.254SerArg: 5.254 ± 0.042	9.473SerSer: 9.473 ± 0.088	5.947SerThr: 5.947 ± 0.048	5.212SerVal: 5.212 ± 0.036	1.124SerTrp: 1.124 ± 0.016	2.001SerTyr: 2.001 ± 0.021	0.001SerXaa: 0.001 ± 0.0
Thr	5.595ThrAla: 5.595 ± 0.037	0.82ThrCys: 0.82 ± 0.016	2.736ThrAsp: 2.736 ± 0.024	2.82ThrGlu: 2.82 ± 0.024	2.445ThrPhe: 2.445 ± 0.024	3.918ThrGly: 3.918 ± 0.034	1.589ThrHis: 1.589 ± 0.018	2.912ThrIle: 2.912 ± 0.025	2.309ThrLys: 2.309 ± 0.023	6.062ThrLeu: 6.062 ± 0.041	1.208ThrMet: 1.208 ± 0.015	1.88ThrAsn: 1.88 ± 0.022	4.822ThrPro: 4.822 ± 0.044	2.071ThrGln: 2.071 ± 0.022	3.582ThrArg: 3.582 ± 0.03	5.616ThrSer: 5.616 ± 0.046	4.12ThrThr: 4.12 ± 0.039	4.105ThrVal: 4.105 ± 0.03	0.867ThrTrp: 0.867 ± 0.015	1.638ThrTyr: 1.638 ± 0.019	0.001ThrXaa: 0.001 ± 0.0
Val	5.974ValAla: 5.974 ± 0.039	0.97ValCys: 0.97 ± 0.015	3.961ValAsp: 3.961 ± 0.031	3.949ValGlu: 3.949 ± 0.034	2.604ValPhe: 2.604 ± 0.025	4.067ValGly: 4.067 ± 0.03	1.773ValHis: 1.773 ± 0.019	2.974ValIle: 2.974 ± 0.028	2.821ValLys: 2.821 ± 0.029	6.469ValLeu: 6.469 ± 0.043	1.307ValMet: 1.307 ± 0.017	2.116ValAsn: 2.116 ± 0.024	4.316ValPro: 4.316 ± 0.034	2.563ValGln: 2.563 ± 0.02	4.099ValArg: 4.099 ± 0.032	4.999ValSer: 4.999 ± 0.036	3.664ValThr: 3.664 ± 0.028	5.032ValVal: 5.032 ± 0.041	1.026ValTrp: 1.026 ± 0.018	1.907ValTyr: 1.907 ± 0.022	0.002ValXaa: 0.002 ± 0.001
Trp	1.258TrpAla: 1.258 ± 0.015	0.225TrpCys: 0.225 ± 0.007	0.919TrpAsp: 0.919 ± 0.014	0.832TrpGlu: 0.832 ± 0.014	0.542TrpPhe: 0.542 ± 0.011	0.894TrpGly: 0.894 ± 0.014	0.373TrpHis: 0.373 ± 0.01	0.729TrpIle: 0.729 ± 0.015	0.739TrpLys: 0.739 ± 0.013	1.364TrpLeu: 1.364 ± 0.016	0.344TrpMet: 0.344 ± 0.007	0.549TrpAsn: 0.549 ± 0.011	0.658TrpPro: 0.658 ± 0.014	0.542TrpGln: 0.542 ± 0.011	1.062TrpArg: 1.062 ± 0.014	1.108TrpSer: 1.108 ± 0.017	0.965TrpThr: 0.965 ± 0.015	0.878TrpVal: 0.878 ± 0.014	0.283TrpTrp: 0.283 ± 0.007	0.44TrpTyr: 0.44 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.377TyrAla: 2.377 ± 0.023	0.404TyrCys: 0.404 ± 0.01	1.641TyrAsp: 1.641 ± 0.02	1.432TyrGlu: 1.432 ± 0.018	1.111TyrPhe: 1.111 ± 0.015	1.852TyrGly: 1.852 ± 0.025	0.738TyrHis: 0.738 ± 0.012	1.332TyrIle: 1.332 ± 0.017	1.039TyrLys: 1.039 ± 0.016	2.545TyrLeu: 2.545 ± 0.025	0.572TyrMet: 0.572 ± 0.011	0.983TyrAsn: 0.983 ± 0.015	1.567TyrPro: 1.567 ± 0.023	0.925TyrGln: 0.925 ± 0.015	1.562TyrArg: 1.562 ± 0.019	1.975TyrSer: 1.975 ± 0.022	1.686TyrThr: 1.686 ± 0.019	1.813TyrVal: 1.813 ± 0.021	0.404TyrTrp: 0.404 ± 0.01	0.853TyrTyr: 0.853 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.001	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.001	0.001XaaGlu: 0.001 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.002XaaGly: 0.002 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.001XaaLeu: 0.001 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.001	0.001XaaGln: 0.001 ± 0.0	0.002XaaArg: 0.002 ± 0.001	0.001XaaSer: 0.001 ± 0.001	0.001XaaThr: 0.001 ± 0.0	0.002XaaVal: 0.002 ± 0.001	0.001XaaTrp: 0.001 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.02XaaXaa: 0.02 ± 0.006

Statistics based on 11848 proteins (4868893 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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