Amino acid dipepetide frequency for Tistrella mobilis (strain KA081020-065)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	24.687AlaAla: 24.687 ± 0.218	1.142AlaCys: 1.142 ± 0.028	8.751AlaAsp: 8.751 ± 0.088	8.783AlaGlu: 8.783 ± 0.094	4.36AlaPhe: 4.36 ± 0.054	14.959AlaGly: 14.959 ± 0.106	2.488AlaHis: 2.488 ± 0.046	6.244AlaIle: 6.244 ± 0.071	2.555AlaLys: 2.555 ± 0.045	15.144AlaLeu: 15.144 ± 0.128	3.729AlaMet: 3.729 ± 0.047	2.083AlaAsn: 2.083 ± 0.032	7.034AlaPro: 7.034 ± 0.084	3.332AlaGln: 3.332 ± 0.048	11.998AlaArg: 11.998 ± 0.118	5.331AlaSer: 5.331 ± 0.06	6.853AlaThr: 6.853 ± 0.071	10.704AlaVal: 10.704 ± 0.085	1.902AlaTrp: 1.902 ± 0.031	2.356AlaTyr: 2.356 ± 0.034	0.0AlaXaa: 0.0 ± 0.0
Cys	0.866CysAla: 0.866 ± 0.021	0.098CysCys: 0.098 ± 0.007	0.39CysAsp: 0.39 ± 0.015	0.281CysGlu: 0.281 ± 0.012	0.279CysPhe: 0.279 ± 0.014	0.806CysGly: 0.806 ± 0.021	0.21CysHis: 0.21 ± 0.012	0.325CysIle: 0.325 ± 0.014	0.101CysLys: 0.101 ± 0.008	0.803CysLeu: 0.803 ± 0.022	0.142CysMet: 0.142 ± 0.008	0.154CysAsn: 0.154 ± 0.01	0.475CysPro: 0.475 ± 0.015	0.158CysGln: 0.158 ± 0.01	0.685CysArg: 0.685 ± 0.019	0.343CysSer: 0.343 ± 0.013	0.386CysThr: 0.386 ± 0.016	0.464CysVal: 0.464 ± 0.018	0.107CysTrp: 0.107 ± 0.007	0.173CysTyr: 0.173 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	8.102AspAla: 8.102 ± 0.074	0.441AspCys: 0.441 ± 0.018	3.833AspAsp: 3.833 ± 0.068	3.429AspGlu: 3.429 ± 0.051	1.928AspPhe: 1.928 ± 0.03	6.398AspGly: 6.398 ± 0.091	1.499AspHis: 1.499 ± 0.034	2.621AspIle: 2.621 ± 0.041	0.991AspLys: 0.991 ± 0.026	6.909AspLeu: 6.909 ± 0.071	1.403AspMet: 1.403 ± 0.028	0.885AspAsn: 0.885 ± 0.023	4.492AspPro: 4.492 ± 0.054	1.956AspGln: 1.956 ± 0.03	6.143AspArg: 6.143 ± 0.062	1.514AspSer: 1.514 ± 0.035	2.655AspThr: 2.655 ± 0.045	4.015AspVal: 4.015 ± 0.053	1.083AspTrp: 1.083 ± 0.022	1.348AspTyr: 1.348 ± 0.031	0.0AspXaa: 0.0 ± 0.0
Glu	8.658GluAla: 8.658 ± 0.085	0.23GluCys: 0.23 ± 0.011	2.916GluAsp: 2.916 ± 0.041	2.502GluGlu: 2.502 ± 0.052	1.191GluPhe: 1.191 ± 0.025	4.287GluGly: 4.287 ± 0.059	0.989GluHis: 0.989 ± 0.024	3.208GluIle: 3.208 ± 0.043	1.259GluLys: 1.259 ± 0.032	4.789GluLeu: 4.789 ± 0.052	1.405GluMet: 1.405 ± 0.025	1.057GluAsn: 1.057 ± 0.025	2.686GluPro: 2.686 ± 0.041	1.568GluGln: 1.568 ± 0.033	4.61GluArg: 4.61 ± 0.057	1.689GluSer: 1.689 ± 0.024	3.596GluThr: 3.596 ± 0.051	4.075GluVal: 4.075 ± 0.047	0.453GluTrp: 0.453 ± 0.017	0.738GluTyr: 0.738 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	4.406PheAla: 4.406 ± 0.056	0.337PheCys: 0.337 ± 0.012	2.574PheAsp: 2.574 ± 0.039	1.698PheGlu: 1.698 ± 0.033	1.104PhePhe: 1.104 ± 0.025	3.466PheGly: 3.466 ± 0.048	0.654PheHis: 0.654 ± 0.019	1.33PheIle: 1.33 ± 0.029	0.59PheLys: 0.59 ± 0.02	3.008PheLeu: 3.008 ± 0.044	0.72PheMet: 0.72 ± 0.021	0.732PheAsn: 0.732 ± 0.023	1.419PhePro: 1.419 ± 0.027	0.833PheGln: 0.833 ± 0.019	2.432PheArg: 2.432 ± 0.036	1.619PheSer: 1.619 ± 0.036	1.905PheThr: 1.905 ± 0.037	2.431PheVal: 2.431 ± 0.039	0.476PheTrp: 0.476 ± 0.016	0.717PheTyr: 0.717 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	10.866GlyAla: 10.866 ± 0.076	0.801GlyCys: 0.801 ± 0.021	5.023GlyAsp: 5.023 ± 0.069	4.384GlyGlu: 4.384 ± 0.052	3.7GlyPhe: 3.7 ± 0.047	8.556GlyGly: 8.556 ± 0.094	2.041GlyHis: 2.041 ± 0.035	4.752GlyIle: 4.752 ± 0.051	1.9GlyLys: 1.9 ± 0.036	10.943GlyLeu: 10.943 ± 0.091	2.655GlyMet: 2.655 ± 0.045	1.747GlyAsn: 1.747 ± 0.039	4.508GlyPro: 4.508 ± 0.055	2.753GlyGln: 2.753 ± 0.038	8.971GlyArg: 8.971 ± 0.078	4.187GlySer: 4.187 ± 0.052	4.93GlyThr: 4.93 ± 0.06	6.609GlyVal: 6.609 ± 0.057	1.665GlyTrp: 1.665 ± 0.034	2.187GlyTyr: 2.187 ± 0.035	0.0GlyXaa: 0.0 ± 0.0
His	2.545HisAla: 2.545 ± 0.039	0.177HisCys: 0.177 ± 0.01	1.425HisAsp: 1.425 ± 0.033	0.972HisGlu: 0.972 ± 0.024	0.674HisPhe: 0.674 ± 0.018	2.096HisGly: 2.096 ± 0.035	0.622HisHis: 0.622 ± 0.021	0.758HisIle: 0.758 ± 0.023	0.339HisLys: 0.339 ± 0.014	2.305HisLeu: 2.305 ± 0.036	0.477HisMet: 0.477 ± 0.016	0.347HisAsn: 0.347 ± 0.014	1.49HisPro: 1.49 ± 0.026	0.562HisGln: 0.562 ± 0.018	1.612HisArg: 1.612 ± 0.028	0.621HisSer: 0.621 ± 0.019	0.761HisThr: 0.761 ± 0.019	1.491HisVal: 1.491 ± 0.03	0.334HisTrp: 0.334 ± 0.015	0.445HisTyr: 0.445 ± 0.016	0.0HisXaa: 0.0 ± 0.0
Ile	7.572IleAla: 7.572 ± 0.055	0.429IleCys: 0.429 ± 0.015	3.895IleAsp: 3.895 ± 0.052	3.117IleGlu: 3.117 ± 0.038	1.446IlePhe: 1.446 ± 0.03	5.11IleGly: 5.11 ± 0.061	0.893IleHis: 0.893 ± 0.021	1.743IleIle: 1.743 ± 0.03	0.802IleLys: 0.802 ± 0.023	4.305IleLeu: 4.305 ± 0.052	0.854IleMet: 0.854 ± 0.023	1.033IleAsn: 1.033 ± 0.029	2.061IlePro: 2.061 ± 0.035	1.045IleGln: 1.045 ± 0.024	3.949IleArg: 3.949 ± 0.05	2.257IleSer: 2.257 ± 0.036	2.693IleThr: 2.693 ± 0.04	3.458IleVal: 3.458 ± 0.04	0.603IleTrp: 0.603 ± 0.021	1.0IleTyr: 1.0 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	2.978LysAla: 2.978 ± 0.046	0.092LysCys: 0.092 ± 0.007	0.985LysAsp: 0.985 ± 0.029	0.812LysGlu: 0.812 ± 0.026	0.481LysPhe: 0.481 ± 0.016	1.768LysGly: 1.768 ± 0.034	0.304LysHis: 0.304 ± 0.013	1.098LysIle: 1.098 ± 0.027	0.538LysLys: 0.538 ± 0.023	2.299LysLeu: 2.299 ± 0.042	0.482LysMet: 0.482 ± 0.016	0.377LysAsn: 0.377 ± 0.015	1.354LysPro: 1.354 ± 0.03	0.577LysGln: 0.577 ± 0.019	1.582LysArg: 1.582 ± 0.031	1.0LysSer: 1.0 ± 0.027	1.336LysThr: 1.336 ± 0.032	1.687LysVal: 1.687 ± 0.033	0.209LysTrp: 0.209 ± 0.009	0.349LysTyr: 0.349 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	16.678LeuAla: 16.678 ± 0.137	0.758LeuCys: 0.758 ± 0.018	7.222LeuAsp: 7.222 ± 0.071	4.691LeuGlu: 4.691 ± 0.053	3.314LeuPhe: 3.314 ± 0.049	9.243LeuGly: 9.243 ± 0.08	2.012LeuHis: 2.012 ± 0.032	5.394LeuIle: 5.394 ± 0.063	2.8LeuLys: 2.8 ± 0.043	9.936LeuLeu: 9.936 ± 0.107	2.431LeuMet: 2.431 ± 0.039	2.102LeuAsn: 2.102 ± 0.033	6.792LeuPro: 6.792 ± 0.077	2.281LeuGln: 2.281 ± 0.035	7.243LeuArg: 7.243 ± 0.067	5.289LeuSer: 5.289 ± 0.048	5.986LeuThr: 5.986 ± 0.06	8.378LeuVal: 8.378 ± 0.075	1.208LeuTrp: 1.208 ± 0.028	1.943LeuTyr: 1.943 ± 0.033	0.0LeuXaa: 0.0 ± 0.0
Met	3.595MetAla: 3.595 ± 0.044	0.139MetCys: 0.139 ± 0.009	1.07MetAsp: 1.07 ± 0.023	0.96MetGlu: 0.96 ± 0.026	0.621MetPhe: 0.621 ± 0.02	1.876MetGly: 1.876 ± 0.036	0.421MetHis: 0.421 ± 0.017	1.489MetIle: 1.489 ± 0.031	0.612MetLys: 0.612 ± 0.019	2.561MetLeu: 2.561 ± 0.042	0.71MetMet: 0.71 ± 0.021	0.581MetAsn: 0.581 ± 0.018	1.63MetPro: 1.63 ± 0.03	0.672MetGln: 0.672 ± 0.019	1.754MetArg: 1.754 ± 0.033	1.527MetSer: 1.527 ± 0.031	2.239MetThr: 2.239 ± 0.036	1.958MetVal: 1.958 ± 0.033	0.189MetTrp: 0.189 ± 0.01	0.278MetTyr: 0.278 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	2.389AsnAla: 2.389 ± 0.039	0.154AsnCys: 0.154 ± 0.008	1.085AsnAsp: 1.085 ± 0.03	0.813AsnGlu: 0.813 ± 0.026	0.65AsnPhe: 0.65 ± 0.019	1.717AsnGly: 1.717 ± 0.033	0.389AsnHis: 0.389 ± 0.015	0.866AsnIle: 0.866 ± 0.024	0.374AsnLys: 0.374 ± 0.017	2.097AsnLeu: 2.097 ± 0.034	0.437AsnMet: 0.437 ± 0.016	0.433AsnAsn: 0.433 ± 0.017	1.408AsnPro: 1.408 ± 0.029	0.568AsnGln: 0.568 ± 0.016	1.583AsnArg: 1.583 ± 0.031	0.696AsnSer: 0.696 ± 0.021	0.942AsnThr: 0.942 ± 0.027	1.358AsnVal: 1.358 ± 0.028	0.288AsnTrp: 0.288 ± 0.014	0.46AsnTyr: 0.46 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	9.181ProAla: 9.181 ± 0.098	0.282ProCys: 0.282 ± 0.012	4.446ProAsp: 4.446 ± 0.051	4.142ProGlu: 4.142 ± 0.049	1.795ProPhe: 1.795 ± 0.033	5.662ProGly: 5.662 ± 0.056	1.123ProHis: 1.123 ± 0.023	2.014ProIle: 2.014 ± 0.032	1.203ProLys: 1.203 ± 0.03	5.324ProLeu: 5.324 ± 0.055	1.292ProMet: 1.292 ± 0.028	0.863ProAsn: 0.863 ± 0.021	3.099ProPro: 3.099 ± 0.057	1.436ProGln: 1.436 ± 0.031	3.704ProArg: 3.704 ± 0.049	2.307ProSer: 2.307 ± 0.032	2.45ProThr: 2.45 ± 0.042	5.303ProVal: 5.303 ± 0.061	0.789ProTrp: 0.789 ± 0.021	1.02ProTyr: 1.02 ± 0.024	0.0ProXaa: 0.0 ± 0.0
Gln	4.129GlnAla: 4.129 ± 0.054	0.131GlnCys: 0.131 ± 0.009	1.293GlnAsp: 1.293 ± 0.027	1.074GlnGlu: 1.074 ± 0.025	0.69GlnPhe: 0.69 ± 0.022	2.376GlnGly: 2.376 ± 0.036	0.421GlnHis: 0.421 ± 0.014	1.585GlnIle: 1.585 ± 0.029	0.633GlnLys: 0.633 ± 0.019	2.517GlnLeu: 2.517 ± 0.041	0.749GlnMet: 0.749 ± 0.021	0.547GlnAsn: 0.547 ± 0.017	1.657GlnPro: 1.657 ± 0.032	0.818GlnGln: 0.818 ± 0.027	2.008GlnArg: 2.008 ± 0.038	1.294GlnSer: 1.294 ± 0.026	1.553GlnThr: 1.553 ± 0.032	2.138GlnVal: 2.138 ± 0.039	0.275GlnTrp: 0.275 ± 0.011	0.415GlnTyr: 0.415 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	10.126ArgAla: 10.126 ± 0.093	0.48ArgCys: 0.48 ± 0.018	4.639ArgAsp: 4.639 ± 0.05	3.782ArgGlu: 3.782 ± 0.052	3.058ArgPhe: 3.058 ± 0.039	5.659ArgGly: 5.659 ± 0.053	2.046ArgHis: 2.046 ± 0.036	4.711ArgIle: 4.711 ± 0.052	1.577ArgLys: 1.577 ± 0.033	10.634ArgLeu: 10.634 ± 0.093	2.244ArgMet: 2.244 ± 0.033	1.594ArgAsn: 1.594 ± 0.03	5.091ArgPro: 5.091 ± 0.058	2.479ArgGln: 2.479 ± 0.036	8.175ArgArg: 8.175 ± 0.092	3.526ArgSer: 3.526 ± 0.045	3.549ArgThr: 3.549 ± 0.042	5.615ArgVal: 5.615 ± 0.058	1.127ArgTrp: 1.127 ± 0.026	1.591ArgTyr: 1.591 ± 0.032	0.0ArgXaa: 0.0 ± 0.0
Ser	5.296SerAla: 5.296 ± 0.06	0.35SerCys: 0.35 ± 0.015	2.381SerAsp: 2.381 ± 0.039	1.974SerGlu: 1.974 ± 0.034	1.815SerPhe: 1.815 ± 0.033	4.811SerGly: 4.811 ± 0.059	0.913SerHis: 0.913 ± 0.021	2.071SerIle: 2.071 ± 0.033	0.846SerLys: 0.846 ± 0.022	4.597SerLeu: 4.597 ± 0.053	1.127SerMet: 1.127 ± 0.025	0.838SerAsn: 0.838 ± 0.024	2.461SerPro: 2.461 ± 0.036	1.07SerGln: 1.07 ± 0.026	3.258SerArg: 3.258 ± 0.044	2.04SerSer: 2.04 ± 0.039	2.288SerThr: 2.288 ± 0.034	3.128SerVal: 3.128 ± 0.052	0.7SerTrp: 0.7 ± 0.019	0.988SerTyr: 0.988 ± 0.028	0.0SerXaa: 0.0 ± 0.0
Thr	7.811ThrAla: 7.811 ± 0.084	0.358ThrCys: 0.358 ± 0.014	3.147ThrAsp: 3.147 ± 0.052	2.561ThrGlu: 2.561 ± 0.034	1.554ThrPhe: 1.554 ± 0.033	6.089ThrGly: 6.089 ± 0.068	0.964ThrHis: 0.964 ± 0.022	2.625ThrIle: 2.625 ± 0.047	0.83ThrLys: 0.83 ± 0.024	5.738ThrLeu: 5.738 ± 0.072	1.096ThrMet: 1.096 ± 0.024	0.944ThrAsn: 0.944 ± 0.026	3.717ThrPro: 3.717 ± 0.048	1.086ThrGln: 1.086 ± 0.026	3.974ThrArg: 3.974 ± 0.047	2.391ThrSer: 2.391 ± 0.041	2.986ThrThr: 2.986 ± 0.042	4.478ThrVal: 4.478 ± 0.09	0.557ThrTrp: 0.557 ± 0.019	1.002ThrTyr: 1.002 ± 0.028	0.0ThrXaa: 0.0 ± 0.0
Val	10.694ValAla: 10.694 ± 0.08	0.541ValCys: 0.541 ± 0.017	4.57ValAsp: 4.57 ± 0.072	4.441ValGlu: 4.441 ± 0.048	2.599ValPhe: 2.599 ± 0.038	5.323ValGly: 5.323 ± 0.055	1.342ValHis: 1.342 ± 0.026	4.078ValIle: 4.078 ± 0.052	1.671ValLys: 1.671 ± 0.032	8.149ValLeu: 8.149 ± 0.079	2.108ValMet: 2.108 ± 0.035	1.621ValAsn: 1.621 ± 0.04	4.293ValPro: 4.293 ± 0.047	1.984ValGln: 1.984 ± 0.033	5.084ValArg: 5.084 ± 0.055	3.71ValSer: 3.71 ± 0.049	5.016ValThr: 5.016 ± 0.078	6.732ValVal: 6.732 ± 0.07	0.931ValTrp: 0.931 ± 0.028	1.402ValTyr: 1.402 ± 0.025	0.0ValXaa: 0.0 ± 0.0
Trp	1.434TrpAla: 1.434 ± 0.028	0.136TrpCys: 0.136 ± 0.009	0.581TrpAsp: 0.581 ± 0.02	0.499TrpGlu: 0.499 ± 0.016	0.519TrpPhe: 0.519 ± 0.018	0.926TrpGly: 0.926 ± 0.022	0.31TrpHis: 0.31 ± 0.014	0.673TrpIle: 0.673 ± 0.02	0.315TrpLys: 0.315 ± 0.013	1.64TrpLeu: 1.64 ± 0.029	0.394TrpMet: 0.394 ± 0.014	0.348TrpAsn: 0.348 ± 0.014	0.831TrpPro: 0.831 ± 0.018	0.568TrpGln: 0.568 ± 0.016	1.289TrpArg: 1.289 ± 0.031	0.827TrpSer: 0.827 ± 0.02	0.807TrpThr: 0.807 ± 0.021	0.81TrpVal: 0.81 ± 0.022	0.251TrpTrp: 0.251 ± 0.013	0.286TrpTyr: 0.286 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.423TyrAla: 2.423 ± 0.035	0.17TyrCys: 0.17 ± 0.009	1.418TyrAsp: 1.418 ± 0.033	0.993TyrGlu: 0.993 ± 0.026	0.672TyrPhe: 0.672 ± 0.02	2.05TyrGly: 2.05 ± 0.04	0.411TyrHis: 0.411 ± 0.015	0.681TyrIle: 0.681 ± 0.021	0.373TyrLys: 0.373 ± 0.015	2.002TyrLeu: 2.002 ± 0.034	0.427TyrMet: 0.427 ± 0.014	0.421TyrAsn: 0.421 ± 0.015	0.939TyrPro: 0.939 ± 0.025	0.554TyrGln: 0.554 ± 0.018	1.647TyrArg: 1.647 ± 0.032	0.786TyrSer: 0.786 ± 0.023	0.98TyrThr: 0.98 ± 0.027	1.455TyrVal: 1.455 ± 0.03	0.297TyrTrp: 0.297 ± 0.013	0.493TyrTyr: 0.493 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5778 proteins (1925682 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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