Amino acid dipepetide frequency for Torque teno virus (isolate Human/Germany/KAV/2001) (TTV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.751AlaAla: 8.751 ± 6.086
0.796AlaCys: 0.796 ± 0.481
4.773AlaAsp: 4.773 ± 3.852
7.955AlaGlu: 7.955 ± 3.117
1.591AlaPhe: 1.591 ± 1.284
3.182AlaGly: 3.182 ± 0.322
1.591AlaHis: 1.591 ± 1.284
4.773AlaIle: 4.773 ± 0.855
2.387AlaLys: 2.387 ± 1.627
3.978AlaLeu: 3.978 ± 1.209
0.0AlaMet: 0.0 ± 0.0
0.0AlaAsn: 0.0 ± 0.0
2.387AlaPro: 2.387 ± 2.077
3.978AlaGln: 3.978 ± 1.209
3.978AlaArg: 3.978 ± 1.431
3.182AlaSer: 3.182 ± 1.595
3.182AlaThr: 3.182 ± 1.461
3.182AlaVal: 3.182 ± 1.039
0.796AlaTrp: 0.796 ± 0.481
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
7.955CysGly: 7.955 ± 1.928
0.0CysHis: 0.0 ± 0.0
0.796CysIle: 0.796 ± 0.481
3.182CysLys: 3.182 ± 1.111
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.796CysAsn: 0.796 ± 0.481
1.591CysPro: 1.591 ± 0.963
1.591CysGln: 1.591 ± 1.284
1.591CysArg: 1.591 ± 0.731
0.796CysSer: 0.796 ± 0.946
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.796CysTyr: 0.796 ± 0.481
0.0CysXaa: 0.0 ± 0.0
Asp
8.751AspAla: 8.751 ± 3.693
0.0AspCys: 0.0 ± 0.0
1.591AspAsp: 1.591 ± 1.284
0.796AspGlu: 0.796 ± 0.481
5.569AspPhe: 5.569 ± 1.125
3.182AspGly: 3.182 ± 1.595
0.796AspHis: 0.796 ± 0.481
0.796AspIle: 0.796 ± 0.481
2.387AspLys: 2.387 ± 1.444
7.16AspLeu: 7.16 ± 1.475
0.0AspMet: 0.0 ± 0.0
0.796AspAsn: 0.796 ± 0.481
2.387AspPro: 2.387 ± 0.759
2.387AspGln: 2.387 ± 0.803
2.387AspArg: 2.387 ± 2.077
2.387AspSer: 2.387 ± 0.811
0.796AspThr: 0.796 ± 0.481
2.387AspVal: 2.387 ± 2.033
3.182AspTrp: 3.182 ± 1.63
2.387AspTyr: 2.387 ± 1.444
0.0AspXaa: 0.0 ± 0.0
Glu
1.591GluAla: 1.591 ± 0.963
0.796GluCys: 0.796 ± 0.946
2.387GluAsp: 2.387 ± 2.077
2.387GluGlu: 2.387 ± 1.444
0.796GluPhe: 0.796 ± 0.481
6.364GluGly: 6.364 ± 2.89
0.796GluHis: 0.796 ± 0.481
0.0GluIle: 0.0 ± 0.0
2.387GluLys: 2.387 ± 0.759
0.796GluLeu: 0.796 ± 0.481
0.0GluMet: 0.0 ± 0.0
3.978GluAsn: 3.978 ± 1.193
0.796GluPro: 0.796 ± 0.481
3.978GluGln: 3.978 ± 0.162
4.773GluArg: 4.773 ± 2.175
4.773GluSer: 4.773 ± 1.621
4.773GluThr: 4.773 ± 0.642
2.387GluVal: 2.387 ± 1.444
0.796GluTrp: 0.796 ± 0.481
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.796PheAla: 0.796 ± 0.481
3.978PheCys: 3.978 ± 0.162
0.796PheAsp: 0.796 ± 0.481
0.0PheGlu: 0.0 ± 0.0
1.591PhePhe: 1.591 ± 0.963
3.182PheGly: 3.182 ± 0.322
1.591PheHis: 1.591 ± 0.963
0.796PheIle: 0.796 ± 0.481
4.773PheLys: 4.773 ± 2.888
2.387PheLeu: 2.387 ± 0.811
0.0PheMet: 0.0 ± 0.0
3.978PheAsn: 3.978 ± 1.431
1.591PhePro: 1.591 ± 0.731
4.773PheGln: 4.773 ± 1.865
1.591PheArg: 1.591 ± 0.963
0.796PheSer: 0.796 ± 0.481
3.182PheThr: 3.182 ± 1.925
1.591PheVal: 1.591 ± 1.284
1.591PheTrp: 1.591 ± 0.963
1.591PheTyr: 1.591 ± 0.731
0.0PheXaa: 0.0 ± 0.0
Gly
4.773GlyAla: 4.773 ± 2.842
1.591GlyCys: 1.591 ± 1.284
7.955GlyAsp: 7.955 ± 4.174
3.182GlyGlu: 3.182 ± 1.039
2.387GlyPhe: 2.387 ± 0.759
9.547GlyGly: 9.547 ± 3.212
1.591GlyHis: 1.591 ± 1.284
3.182GlyIle: 3.182 ± 1.925
1.591GlyLys: 1.591 ± 0.738
2.387GlyLeu: 2.387 ± 0.803
1.591GlyMet: 1.591 ± 0.963
2.387GlyAsn: 2.387 ± 1.444
7.955GlyPro: 7.955 ± 1.066
2.387GlyGln: 2.387 ± 0.803
6.364GlyArg: 6.364 ± 2.89
3.182GlySer: 3.182 ± 0.322
1.591GlyThr: 1.591 ± 0.738
1.591GlyVal: 1.591 ± 0.963
0.0GlyTrp: 0.0 ± 0.0
3.182GlyTyr: 3.182 ± 1.925
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
2.387HisGly: 2.387 ± 0.803
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
2.387HisLeu: 2.387 ± 0.803
0.796HisMet: 0.796 ± 0.481
3.182HisAsn: 3.182 ± 2.568
1.591HisPro: 1.591 ± 0.963
1.591HisGln: 1.591 ± 0.963
1.591HisArg: 1.591 ± 0.963
1.591HisSer: 1.591 ± 0.963
0.796HisThr: 0.796 ± 0.481
2.387HisVal: 2.387 ± 0.759
0.796HisTrp: 0.796 ± 0.481
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.796IleAla: 0.796 ± 0.481
2.387IleCys: 2.387 ± 1.444
0.796IleAsp: 0.796 ± 0.481
0.796IleGlu: 0.796 ± 0.481
1.591IlePhe: 1.591 ± 0.963
1.591IleGly: 1.591 ± 0.963
0.796IleHis: 0.796 ± 0.481
1.591IleIle: 1.591 ± 0.963
1.591IleLys: 1.591 ± 0.963
0.796IleLeu: 0.796 ± 0.481
0.0IleMet: 0.0 ± 0.0
0.796IleAsn: 0.796 ± 0.978
4.773IlePro: 4.773 ± 2.888
2.387IleGln: 2.387 ± 1.444
1.591IleArg: 1.591 ± 1.284
0.796IleSer: 0.796 ± 0.978
0.796IleThr: 0.796 ± 0.481
1.591IleVal: 1.591 ± 0.963
0.796IleTrp: 0.796 ± 0.481
3.182IleTyr: 3.182 ± 1.925
0.0IleXaa: 0.0 ± 0.0
Lys
1.591LysAla: 1.591 ± 0.731
0.0LysCys: 0.0 ± 0.0
2.387LysAsp: 2.387 ± 1.444
3.978LysGlu: 3.978 ± 1.508
3.182LysPhe: 3.182 ± 1.925
0.0LysGly: 0.0 ± 0.0
0.796LysHis: 0.796 ± 0.481
2.387LysIle: 2.387 ± 1.444
4.773LysLys: 4.773 ± 1.621
1.591LysLeu: 1.591 ± 0.738
1.591LysMet: 1.591 ± 0.963
3.978LysAsn: 3.978 ± 1.41
3.182LysPro: 3.182 ± 2.557
4.773LysGln: 4.773 ± 0.873
6.364LysArg: 6.364 ± 2.859
1.591LysSer: 1.591 ± 0.738
9.547LysThr: 9.547 ± 1.284
2.387LysVal: 2.387 ± 1.444
0.0LysTrp: 0.0 ± 0.0
2.387LysTyr: 2.387 ± 1.444
0.0LysXaa: 0.0 ± 0.0
Leu
4.773LeuAla: 4.773 ± 0.855
0.0LeuCys: 0.0 ± 0.0
7.16LeuAsp: 7.16 ± 1.475
0.796LeuGlu: 0.796 ± 0.481
2.387LeuPhe: 2.387 ± 0.759
5.569LeuGly: 5.569 ± 2.376
3.182LeuHis: 3.182 ± 1.925
3.182LeuIle: 3.182 ± 1.925
3.182LeuLys: 3.182 ± 1.111
5.569LeuLeu: 5.569 ± 1.125
0.796LeuMet: 0.796 ± 0.481
2.387LeuAsn: 2.387 ± 0.803
5.569LeuPro: 5.569 ± 3.371
3.182LeuGln: 3.182 ± 1.476
3.182LeuArg: 3.182 ± 1.039
5.569LeuSer: 5.569 ± 3.071
7.16LeuThr: 7.16 ± 1.148
3.182LeuVal: 3.182 ± 1.111
3.978LeuTrp: 3.978 ± 0.162
0.796LeuTyr: 0.796 ± 0.481
0.0LeuXaa: 0.0 ± 0.0
Met
0.796MetAla: 0.796 ± 0.481
0.0MetCys: 0.0 ± 0.0
0.796MetAsp: 0.796 ± 0.481
0.0MetGlu: 0.0 ± 0.0
1.591MetPhe: 1.591 ± 0.963
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.796MetIle: 0.796 ± 0.481
0.0MetLys: 0.0 ± 0.0
1.591MetLeu: 1.591 ± 0.738
0.0MetMet: 0.0 ± 0.0
1.591MetAsn: 1.591 ± 0.963
1.591MetPro: 1.591 ± 0.731
1.591MetGln: 1.591 ± 0.963
1.591MetArg: 1.591 ± 1.955
1.591MetSer: 1.591 ± 1.284
0.796MetThr: 0.796 ± 0.481
0.0MetVal: 0.0 ± 0.0
1.591MetTrp: 1.591 ± 0.731
0.796MetTyr: 0.796 ± 0.481
0.0MetXaa: 0.0 ± 0.0
Asn
5.569AsnAla: 5.569 ± 2.342
0.0AsnCys: 0.0 ± 0.0
2.387AsnAsp: 2.387 ± 0.811
0.796AsnGlu: 0.796 ± 0.481
3.182AsnPhe: 3.182 ± 1.925
1.591AsnGly: 1.591 ± 0.963
0.0AsnHis: 0.0 ± 0.0
1.591AsnIle: 1.591 ± 0.963
0.796AsnLys: 0.796 ± 0.978
5.569AsnLeu: 5.569 ± 2.318
1.591AsnMet: 1.591 ± 0.648
2.387AsnAsn: 2.387 ± 0.803
7.955AsnPro: 7.955 ± 1.562
2.387AsnGln: 2.387 ± 2.033
5.569AsnArg: 5.569 ± 3.703
2.387AsnSer: 2.387 ± 0.811
1.591AsnThr: 1.591 ± 0.963
0.796AsnVal: 0.796 ± 0.481
0.796AsnTrp: 0.796 ± 0.481
1.591AsnTyr: 1.591 ± 0.963
0.0AsnXaa: 0.0 ± 0.0
Pro
11.138ProAla: 11.138 ± 5.685
2.387ProCys: 2.387 ± 0.803
3.978ProAsp: 3.978 ± 0.162
1.591ProGlu: 1.591 ± 0.731
3.978ProPhe: 3.978 ± 1.431
7.955ProGly: 7.955 ± 2.385
0.0ProHis: 0.0 ± 0.0
2.387ProIle: 2.387 ± 1.444
6.364ProLys: 6.364 ± 0.812
5.569ProLeu: 5.569 ± 1.884
1.591ProMet: 1.591 ± 0.731
0.0ProAsn: 0.0 ± 0.0
13.524ProPro: 13.524 ± 6.481
7.16ProGln: 7.16 ± 1.403
13.524ProArg: 13.524 ± 3.388
5.569ProSer: 5.569 ± 2.113
1.591ProThr: 1.591 ± 0.731
4.773ProVal: 4.773 ± 2.129
1.591ProTrp: 1.591 ± 1.284
3.182ProTyr: 3.182 ± 1.111
0.0ProXaa: 0.0 ± 0.0
Gln
2.387GlnAla: 2.387 ± 0.759
1.591GlnCys: 1.591 ± 0.963
2.387GlnAsp: 2.387 ± 0.759
6.364GlnGlu: 6.364 ± 1.584
0.796GlnPhe: 0.796 ± 0.481
2.387GlnGly: 2.387 ± 0.759
0.796GlnHis: 0.796 ± 0.481
0.796GlnIle: 0.796 ± 0.481
3.182GlnLys: 3.182 ± 1.111
6.364GlnLeu: 6.364 ± 2.859
3.182GlnMet: 3.182 ± 2.475
3.182GlnAsn: 3.182 ± 1.476
3.182GlnPro: 3.182 ± 2.568
6.364GlnGln: 6.364 ± 0.913
4.773GlnArg: 4.773 ± 1.606
2.387GlnSer: 2.387 ± 0.803
2.387GlnThr: 2.387 ± 1.444
0.796GlnVal: 0.796 ± 0.946
1.591GlnTrp: 1.591 ± 0.963
3.182GlnTyr: 3.182 ± 1.111
0.0GlnXaa: 0.0 ± 0.0
Arg
2.387ArgAla: 2.387 ± 2.033
1.591ArgCys: 1.591 ± 0.731
2.387ArgAsp: 2.387 ± 0.803
3.182ArgGlu: 3.182 ± 1.63
2.387ArgPhe: 2.387 ± 1.444
3.978ArgGly: 3.978 ± 1.41
2.387ArgHis: 2.387 ± 0.803
2.387ArgIle: 2.387 ± 1.444
3.182ArgLys: 3.182 ± 1.111
9.547ArgLeu: 9.547 ± 4.89
0.796ArgMet: 0.796 ± 0.481
3.978ArgAsn: 3.978 ± 2.368
15.115ArgPro: 15.115 ± 1.171
3.978ArgGln: 3.978 ± 1.508
24.662ArgArg: 24.662 ± 7.05
8.751ArgSer: 8.751 ± 4.848
2.387ArgThr: 2.387 ± 0.803
3.978ArgVal: 3.978 ± 1.209
3.182ArgTrp: 3.182 ± 1.925
3.978ArgTyr: 3.978 ± 0.162
0.0ArgXaa: 0.0 ± 0.0
Ser
0.796SerAla: 0.796 ± 0.481
0.0SerCys: 0.0 ± 0.0
1.591SerAsp: 1.591 ± 1.892
2.387SerGlu: 2.387 ± 1.444
1.591SerPhe: 1.591 ± 0.738
0.796SerGly: 0.796 ± 0.481
2.387SerHis: 2.387 ± 0.803
2.387SerIle: 2.387 ± 0.759
5.569SerLys: 5.569 ± 0.752
3.978SerLeu: 3.978 ± 2.087
0.0SerMet: 0.0 ± 0.0
3.182SerAsn: 3.182 ± 2.557
9.547SerPro: 9.547 ± 4.413
0.796SerGln: 0.796 ± 0.481
2.387SerArg: 2.387 ± 0.803
7.16SerSer: 7.16 ± 6.052
7.16SerThr: 7.16 ± 3.8
3.182SerVal: 3.182 ± 0.322
2.387SerTrp: 2.387 ± 0.803
1.591SerTyr: 1.591 ± 0.731
0.0SerXaa: 0.0 ± 0.0
Thr
2.387ThrAla: 2.387 ± 1.658
1.591ThrCys: 1.591 ± 0.738
3.978ThrAsp: 3.978 ± 0.162
3.978ThrGlu: 3.978 ± 1.209
5.569ThrPhe: 5.569 ± 2.318
3.182ThrGly: 3.182 ± 1.039
0.0ThrHis: 0.0 ± 0.0
0.0ThrIle: 0.0 ± 0.0
5.569ThrLys: 5.569 ± 2.318
3.182ThrLeu: 3.182 ± 1.925
0.796ThrMet: 0.796 ± 0.481
2.387ThrAsn: 2.387 ± 1.444
3.182ThrPro: 3.182 ± 2.568
2.387ThrGln: 2.387 ± 1.444
5.569ThrArg: 5.569 ± 2.185
3.978ThrSer: 3.978 ± 2.343
3.978ThrThr: 3.978 ± 1.431
3.182ThrVal: 3.182 ± 1.925
0.796ThrTrp: 0.796 ± 0.481
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
2.387ValAla: 2.387 ± 0.811
1.591ValCys: 1.591 ± 1.284
1.591ValAsp: 1.591 ± 0.963
2.387ValGlu: 2.387 ± 2.033
0.796ValPhe: 0.796 ± 0.481
1.591ValGly: 1.591 ± 1.284
1.591ValHis: 1.591 ± 0.731
0.0ValIle: 0.0 ± 0.0
3.182ValLys: 3.182 ± 1.925
4.773ValLeu: 4.773 ± 0.642
0.0ValMet: 0.0 ± 0.0
2.387ValAsn: 2.387 ± 0.811
6.364ValPro: 6.364 ± 1.604
2.387ValGln: 2.387 ± 1.627
3.182ValArg: 3.182 ± 1.925
1.591ValSer: 1.591 ± 0.731
1.591ValThr: 1.591 ± 0.963
1.591ValVal: 1.591 ± 0.963
0.796ValTrp: 0.796 ± 0.978
0.796ValTyr: 0.796 ± 0.481
0.0ValXaa: 0.0 ± 0.0
Trp
0.796TrpAla: 0.796 ± 0.481
0.796TrpCys: 0.796 ± 0.481
1.591TrpAsp: 1.591 ± 0.731
1.591TrpGlu: 1.591 ± 0.731
0.0TrpPhe: 0.0 ± 0.0
3.182TrpGly: 3.182 ± 1.925
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.796TrpLys: 0.796 ± 0.481
2.387TrpLeu: 2.387 ± 0.803
1.591TrpMet: 1.591 ± 0.731
0.796TrpAsn: 0.796 ± 0.481
0.796TrpPro: 0.796 ± 0.946
0.796TrpGln: 0.796 ± 0.481
4.773TrpArg: 4.773 ± 0.642
0.0TrpSer: 0.0 ± 0.0
1.591TrpThr: 1.591 ± 0.731
0.0TrpVal: 0.0 ± 0.0
1.591TrpTrp: 1.591 ± 0.963
3.182TrpTyr: 3.182 ± 0.322
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.0TyrCys: 0.0 ± 0.0
1.591TyrAsp: 1.591 ± 0.963
2.387TyrGlu: 2.387 ± 1.444
1.591TyrPhe: 1.591 ± 0.963
0.796TyrGly: 0.796 ± 0.481
0.796TyrHis: 0.796 ± 0.481
1.591TyrIle: 1.591 ± 0.963
1.591TyrLys: 1.591 ± 0.738
1.591TyrLeu: 1.591 ± 0.738
1.591TyrMet: 1.591 ± 0.963
6.364TyrAsn: 6.364 ± 3.851
4.773TyrPro: 4.773 ± 1.517
0.0TyrGln: 0.0 ± 0.0
4.773TyrArg: 4.773 ± 1.606
0.796TyrSer: 0.796 ± 0.481
0.796TyrThr: 0.796 ± 0.481
1.591TyrVal: 1.591 ± 0.963
0.0TyrTrp: 0.0 ± 0.0
0.796TyrTyr: 0.796 ± 0.481
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1258 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski