Amino acid dipepetide frequency for Tortoise microvirus 62

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.114AlaAla: 5.114 ± 1.592
1.136AlaCys: 1.136 ± 0.527
3.409AlaAsp: 3.409 ± 1.457
3.409AlaGlu: 3.409 ± 1.273
4.545AlaPhe: 4.545 ± 1.929
4.545AlaGly: 4.545 ± 1.76
0.568AlaHis: 0.568 ± 0.56
1.705AlaIle: 1.705 ± 0.888
5.114AlaLys: 5.114 ± 2.09
7.955AlaLeu: 7.955 ± 1.056
2.841AlaMet: 2.841 ± 1.451
3.977AlaAsn: 3.977 ± 1.609
3.977AlaPro: 3.977 ± 1.039
2.841AlaGln: 2.841 ± 0.903
1.705AlaArg: 1.705 ± 0.814
11.932AlaSer: 11.932 ± 2.598
2.273AlaThr: 2.273 ± 0.885
4.545AlaVal: 4.545 ± 1.468
0.0AlaTrp: 0.0 ± 0.0
5.114AlaTyr: 5.114 ± 1.176
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.136CysCys: 1.136 ± 1.121
1.705CysAsp: 1.705 ± 0.848
0.0CysGlu: 0.0 ± 0.0
1.705CysPhe: 1.705 ± 2.217
0.568CysGly: 0.568 ± 0.56
0.0CysHis: 0.0 ± 0.0
0.568CysIle: 0.568 ± 0.37
2.273CysLys: 2.273 ± 1.439
2.273CysLeu: 2.273 ± 1.69
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.568CysGln: 0.568 ± 0.37
2.273CysArg: 2.273 ± 1.34
0.568CysSer: 0.568 ± 0.675
1.136CysThr: 1.136 ± 0.61
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.568CysTyr: 0.568 ± 0.56
0.0CysXaa: 0.0 ± 0.0
Asp
5.114AspAla: 5.114 ± 1.543
2.841AspCys: 2.841 ± 1.113
6.25AspAsp: 6.25 ± 1.969
5.114AspGlu: 5.114 ± 1.512
4.545AspPhe: 4.545 ± 1.699
1.705AspGly: 1.705 ± 1.15
0.568AspHis: 0.568 ± 0.598
5.114AspIle: 5.114 ± 2.041
2.841AspLys: 2.841 ± 0.927
3.409AspLeu: 3.409 ± 1.145
0.568AspMet: 0.568 ± 0.37
2.273AspAsn: 2.273 ± 0.622
1.136AspPro: 1.136 ± 0.681
1.136AspGln: 1.136 ± 0.921
2.841AspArg: 2.841 ± 0.735
3.409AspSer: 3.409 ± 1.436
4.545AspThr: 4.545 ± 1.183
3.409AspVal: 3.409 ± 1.148
0.568AspTrp: 0.568 ± 0.56
3.977AspTyr: 3.977 ± 1.27
0.0AspXaa: 0.0 ± 0.0
Glu
6.25GluAla: 6.25 ± 2.426
1.136GluCys: 1.136 ± 1.353
0.568GluAsp: 0.568 ± 0.673
1.136GluGlu: 1.136 ± 0.921
1.136GluPhe: 1.136 ± 1.11
0.0GluGly: 0.0 ± 0.0
0.568GluHis: 0.568 ± 0.959
5.682GluIle: 5.682 ± 1.093
1.705GluLys: 1.705 ± 0.84
9.091GluLeu: 9.091 ± 1.297
1.136GluMet: 1.136 ± 0.854
0.568GluAsn: 0.568 ± 0.461
2.273GluPro: 2.273 ± 1.218
1.136GluGln: 1.136 ± 0.921
3.977GluArg: 3.977 ± 1.072
3.409GluSer: 3.409 ± 1.695
3.409GluThr: 3.409 ± 0.955
3.409GluVal: 3.409 ± 1.954
0.568GluTrp: 0.568 ± 0.37
1.705GluTyr: 1.705 ± 0.945
0.0GluXaa: 0.0 ± 0.0
Phe
2.841PheAla: 2.841 ± 1.418
0.568PheCys: 0.568 ± 0.56
5.114PheAsp: 5.114 ± 2.148
1.705PheGlu: 1.705 ± 0.848
3.409PhePhe: 3.409 ± 1.285
2.841PheGly: 2.841 ± 0.687
0.568PheHis: 0.568 ± 0.959
2.273PheIle: 2.273 ± 1.123
2.273PheLys: 2.273 ± 0.999
3.977PheLeu: 3.977 ± 1.044
1.705PheMet: 1.705 ± 1.839
5.114PheAsn: 5.114 ± 1.552
3.409PhePro: 3.409 ± 0.758
2.273PheGln: 2.273 ± 0.684
2.841PheArg: 2.841 ± 0.961
2.273PheSer: 2.273 ± 0.936
3.409PheThr: 3.409 ± 1.385
3.977PheVal: 3.977 ± 1.876
0.568PheTrp: 0.568 ± 0.676
3.977PheTyr: 3.977 ± 1.313
0.0PheXaa: 0.0 ± 0.0
Gly
3.977GlyAla: 3.977 ± 1.646
0.568GlyCys: 0.568 ± 0.37
2.273GlyAsp: 2.273 ± 1.207
2.273GlyGlu: 2.273 ± 1.743
4.545GlyPhe: 4.545 ± 1.71
2.841GlyGly: 2.841 ± 1.365
2.273GlyHis: 2.273 ± 1.105
3.409GlyIle: 3.409 ± 1.108
3.977GlyLys: 3.977 ± 1.121
5.682GlyLeu: 5.682 ± 2.44
1.136GlyMet: 1.136 ± 0.977
1.705GlyAsn: 1.705 ± 1.111
0.0GlyPro: 0.0 ± 0.0
0.568GlyGln: 0.568 ± 0.461
1.705GlyArg: 1.705 ± 0.508
6.818GlySer: 6.818 ± 1.087
2.841GlyThr: 2.841 ± 1.347
1.705GlyVal: 1.705 ± 0.888
0.0GlyTrp: 0.0 ± 0.0
3.977GlyTyr: 3.977 ± 0.908
0.0GlyXaa: 0.0 ± 0.0
His
2.841HisAla: 2.841 ± 0.927
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.568HisGlu: 0.568 ± 0.673
0.568HisPhe: 0.568 ± 0.675
1.705HisGly: 1.705 ± 1.839
0.0HisHis: 0.0 ± 0.0
1.136HisIle: 1.136 ± 0.741
0.568HisLys: 0.568 ± 0.598
1.705HisLeu: 1.705 ± 0.637
1.136HisMet: 1.136 ± 0.672
0.568HisAsn: 0.568 ± 0.461
1.705HisPro: 1.705 ± 1.58
0.0HisGln: 0.0 ± 0.0
1.705HisArg: 1.705 ± 1.019
3.409HisSer: 3.409 ± 1.541
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.568HisTrp: 0.568 ± 0.56
1.136HisTyr: 1.136 ± 0.95
0.0HisXaa: 0.0 ± 0.0
Ile
3.977IleAla: 3.977 ± 1.029
0.0IleCys: 0.0 ± 0.0
3.409IleAsp: 3.409 ± 1.521
2.841IleGlu: 2.841 ± 1.279
1.136IlePhe: 1.136 ± 0.5
2.273IleGly: 2.273 ± 1.068
0.568IleHis: 0.568 ± 0.37
1.705IleIle: 1.705 ± 1.111
1.136IleLys: 1.136 ± 0.917
5.114IleLeu: 5.114 ± 1.85
1.136IleMet: 1.136 ± 0.741
3.409IleAsn: 3.409 ± 1.224
3.409IlePro: 3.409 ± 1.596
0.568IleGln: 0.568 ± 0.461
2.273IleArg: 2.273 ± 0.742
6.818IleSer: 6.818 ± 1.907
1.136IleThr: 1.136 ± 0.672
2.841IleVal: 2.841 ± 1.222
1.136IleTrp: 1.136 ± 0.917
3.409IleTyr: 3.409 ± 1.51
0.0IleXaa: 0.0 ± 0.0
Lys
2.273LysAla: 2.273 ± 1.257
0.568LysCys: 0.568 ± 0.959
2.841LysAsp: 2.841 ± 1.29
3.977LysGlu: 3.977 ± 1.578
1.136LysPhe: 1.136 ± 0.86
2.273LysGly: 2.273 ± 0.738
0.0LysHis: 0.0 ± 0.0
1.136LysIle: 1.136 ± 1.082
1.705LysLys: 1.705 ± 1.309
2.273LysLeu: 2.273 ± 1.834
1.136LysMet: 1.136 ± 0.806
2.273LysAsn: 2.273 ± 0.858
1.136LysPro: 1.136 ± 0.762
1.705LysGln: 1.705 ± 0.859
3.977LysArg: 3.977 ± 2.351
3.409LysSer: 3.409 ± 1.883
3.409LysThr: 3.409 ± 0.82
3.977LysVal: 3.977 ± 0.772
1.136LysTrp: 1.136 ± 0.61
1.705LysTyr: 1.705 ± 1.022
0.0LysXaa: 0.0 ± 0.0
Leu
7.955LeuAla: 7.955 ± 2.268
1.136LeuCys: 1.136 ± 1.04
5.114LeuAsp: 5.114 ± 1.873
5.682LeuGlu: 5.682 ± 0.883
4.545LeuPhe: 4.545 ± 1.663
6.25LeuGly: 6.25 ± 1.828
2.273LeuHis: 2.273 ± 1.194
3.409LeuIle: 3.409 ± 2.285
5.114LeuLys: 5.114 ± 2.144
3.409LeuLeu: 3.409 ± 0.956
2.273LeuMet: 2.273 ± 0.962
3.409LeuAsn: 3.409 ± 1.436
6.25LeuPro: 6.25 ± 2.209
1.705LeuGln: 1.705 ± 0.838
5.682LeuArg: 5.682 ± 1.085
9.659LeuSer: 9.659 ± 1.298
5.682LeuThr: 5.682 ± 2.05
6.25LeuVal: 6.25 ± 2.076
0.568LeuTrp: 0.568 ± 0.37
5.114LeuTyr: 5.114 ± 1.413
0.0LeuXaa: 0.0 ± 0.0
Met
2.841MetAla: 2.841 ± 1.067
0.568MetCys: 0.568 ± 0.959
2.273MetAsp: 2.273 ± 0.815
0.568MetGlu: 0.568 ± 0.959
1.136MetPhe: 1.136 ± 0.95
2.273MetGly: 2.273 ± 1.124
0.568MetHis: 0.568 ± 0.461
0.0MetIle: 0.0 ± 0.0
2.273MetLys: 2.273 ± 1.626
4.545MetLeu: 4.545 ± 2.422
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.136MetPro: 1.136 ± 0.5
1.136MetGln: 1.136 ± 0.921
2.841MetArg: 2.841 ± 1.27
3.409MetSer: 3.409 ± 1.501
2.273MetThr: 2.273 ± 0.973
0.0MetVal: 0.0 ± 0.0
0.568MetTrp: 0.568 ± 0.37
0.568MetTyr: 0.568 ± 0.37
0.0MetXaa: 0.0 ± 0.0
Asn
2.841AsnAla: 2.841 ± 0.96
0.0AsnCys: 0.0 ± 0.0
2.273AsnAsp: 2.273 ± 0.904
0.0AsnGlu: 0.0 ± 0.0
1.136AsnPhe: 1.136 ± 0.527
4.545AsnGly: 4.545 ± 1.887
0.0AsnHis: 0.0 ± 0.0
1.705AsnIle: 1.705 ± 0.75
2.273AsnLys: 2.273 ± 1.072
5.114AsnLeu: 5.114 ± 1.423
1.136AsnMet: 1.136 ± 0.842
3.977AsnAsn: 3.977 ± 1.228
2.273AsnPro: 2.273 ± 0.9
3.409AsnGln: 3.409 ± 1.009
3.409AsnArg: 3.409 ± 1.777
3.409AsnSer: 3.409 ± 1.399
2.841AsnThr: 2.841 ± 1.22
1.136AsnVal: 1.136 ± 0.741
0.0AsnTrp: 0.0 ± 0.0
2.841AsnTyr: 2.841 ± 0.917
0.0AsnXaa: 0.0 ± 0.0
Pro
1.136ProAla: 1.136 ± 0.672
0.568ProCys: 0.568 ± 0.598
3.409ProAsp: 3.409 ± 1.323
1.705ProGlu: 1.705 ± 1.58
3.409ProPhe: 3.409 ± 0.847
1.705ProGly: 1.705 ± 0.888
1.136ProHis: 1.136 ± 0.5
2.841ProIle: 2.841 ± 1.276
1.136ProLys: 1.136 ± 0.995
7.955ProLeu: 7.955 ± 1.474
1.136ProMet: 1.136 ± 0.921
0.568ProAsn: 0.568 ± 0.37
1.136ProPro: 1.136 ± 0.639
2.841ProGln: 2.841 ± 1.067
1.705ProArg: 1.705 ± 0.755
5.114ProSer: 5.114 ± 1.772
4.545ProThr: 4.545 ± 0.947
2.273ProVal: 2.273 ± 0.999
0.0ProTrp: 0.0 ± 0.0
2.273ProTyr: 2.273 ± 1.481
0.0ProXaa: 0.0 ± 0.0
Gln
2.841GlnAla: 2.841 ± 1.793
0.0GlnCys: 0.0 ± 0.0
1.136GlnAsp: 1.136 ± 0.5
1.705GlnGlu: 1.705 ± 1.382
3.409GlnPhe: 3.409 ± 0.829
1.136GlnGly: 1.136 ± 0.917
0.0GlnHis: 0.0 ± 0.0
1.136GlnIle: 1.136 ± 0.5
1.705GlnLys: 1.705 ± 1.382
1.136GlnLeu: 1.136 ± 0.681
1.136GlnMet: 1.136 ± 0.628
1.705GlnAsn: 1.705 ± 0.718
0.568GlnPro: 0.568 ± 0.37
4.545GlnGln: 4.545 ± 3.137
5.114GlnArg: 5.114 ± 1.489
3.409GlnSer: 3.409 ± 1.5
3.409GlnThr: 3.409 ± 1.33
2.273GlnVal: 2.273 ± 1.244
0.568GlnTrp: 0.568 ± 0.461
1.136GlnTyr: 1.136 ± 0.921
0.0GlnXaa: 0.0 ± 0.0
Arg
5.114ArgAla: 5.114 ± 1.44
1.136ArgCys: 1.136 ± 0.888
3.409ArgAsp: 3.409 ± 1.24
1.705ArgGlu: 1.705 ± 1.022
2.273ArgPhe: 2.273 ± 0.759
3.977ArgGly: 3.977 ± 1.766
1.136ArgHis: 1.136 ± 0.715
2.841ArgIle: 2.841 ± 1.701
2.273ArgLys: 2.273 ± 1.444
6.818ArgLeu: 6.818 ± 1.947
3.409ArgMet: 3.409 ± 1.362
2.841ArgAsn: 2.841 ± 0.839
2.841ArgPro: 2.841 ± 1.203
2.273ArgGln: 2.273 ± 1.843
2.841ArgArg: 2.841 ± 0.848
6.818ArgSer: 6.818 ± 1.516
2.841ArgThr: 2.841 ± 0.735
1.705ArgVal: 1.705 ± 1.681
0.568ArgTrp: 0.568 ± 0.461
3.409ArgTyr: 3.409 ± 1.061
0.0ArgXaa: 0.0 ± 0.0
Ser
7.386SerAla: 7.386 ± 1.269
0.568SerCys: 0.568 ± 0.37
8.523SerAsp: 8.523 ± 1.502
7.955SerGlu: 7.955 ± 2.89
5.114SerPhe: 5.114 ± 1.483
6.25SerGly: 6.25 ± 2.697
2.841SerHis: 2.841 ± 1.469
5.682SerIle: 5.682 ± 2.176
1.136SerLys: 1.136 ± 0.741
7.386SerLeu: 7.386 ± 2.261
3.977SerMet: 3.977 ± 1.445
4.545SerAsn: 4.545 ± 1.369
5.114SerPro: 5.114 ± 1.304
2.841SerGln: 2.841 ± 1.22
3.409SerArg: 3.409 ± 1.154
15.341SerSer: 15.341 ± 2.714
6.25SerThr: 6.25 ± 1.392
2.841SerVal: 2.841 ± 1.129
2.841SerTrp: 2.841 ± 1.723
3.977SerTyr: 3.977 ± 1.333
0.0SerXaa: 0.0 ± 0.0
Thr
6.818ThrAla: 6.818 ± 1.699
1.136ThrCys: 1.136 ± 0.664
2.273ThrAsp: 2.273 ± 0.858
1.136ThrGlu: 1.136 ± 1.11
4.545ThrPhe: 4.545 ± 1.91
2.841ThrGly: 2.841 ± 0.96
0.568ThrHis: 0.568 ± 0.676
3.409ThrIle: 3.409 ± 0.93
1.705ThrLys: 1.705 ± 0.908
2.273ThrLeu: 2.273 ± 0.795
1.705ThrMet: 1.705 ± 0.89
1.705ThrAsn: 1.705 ± 0.878
1.705ThrPro: 1.705 ± 0.718
4.545ThrGln: 4.545 ± 2.248
3.977ThrArg: 3.977 ± 1.179
4.545ThrSer: 4.545 ± 1.254
2.273ThrThr: 2.273 ± 0.63
3.977ThrVal: 3.977 ± 1.211
0.568ThrTrp: 0.568 ± 0.37
3.409ThrTyr: 3.409 ± 1.065
0.0ThrXaa: 0.0 ± 0.0
Val
4.545ValAla: 4.545 ± 0.995
1.136ValCys: 1.136 ± 1.329
3.409ValAsp: 3.409 ± 1.133
4.545ValGlu: 4.545 ± 2.89
1.705ValPhe: 1.705 ± 0.859
2.273ValGly: 2.273 ± 1.423
1.136ValHis: 1.136 ± 0.639
1.705ValIle: 1.705 ± 0.661
2.273ValLys: 2.273 ± 1.054
5.114ValLeu: 5.114 ± 1.797
1.136ValMet: 1.136 ± 0.914
2.273ValAsn: 2.273 ± 1.323
6.818ValPro: 6.818 ± 2.125
1.136ValGln: 1.136 ± 1.082
2.841ValArg: 2.841 ± 1.146
4.545ValSer: 4.545 ± 1.261
0.568ValThr: 0.568 ± 0.461
2.273ValVal: 2.273 ± 0.912
0.0ValTrp: 0.0 ± 0.0
0.568ValTyr: 0.568 ± 0.37
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.568TrpAsp: 0.568 ± 0.675
0.568TrpGlu: 0.568 ± 0.598
1.136TrpPhe: 1.136 ± 0.672
0.0TrpGly: 0.0 ± 0.0
1.705TrpHis: 1.705 ± 1.839
0.568TrpIle: 0.568 ± 0.37
0.0TrpLys: 0.0 ± 0.0
1.705TrpLeu: 1.705 ± 1.097
0.0TrpMet: 0.0 ± 0.0
0.568TrpAsn: 0.568 ± 0.37
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.705TrpArg: 1.705 ± 0.687
0.568TrpSer: 0.568 ± 0.37
0.568TrpThr: 0.568 ± 0.37
0.568TrpVal: 0.568 ± 0.37
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.841TyrAla: 2.841 ± 0.748
1.136TyrCys: 1.136 ± 0.842
3.409TyrAsp: 3.409 ± 1.506
2.273TyrGlu: 2.273 ± 1.517
3.977TyrPhe: 3.977 ± 1.251
2.273TyrGly: 2.273 ± 0.622
2.841TyrHis: 2.841 ± 1.029
2.273TyrIle: 2.273 ± 1.068
0.568TyrLys: 0.568 ± 0.56
4.545TyrLeu: 4.545 ± 1.458
1.705TyrMet: 1.705 ± 0.696
2.841TyrAsn: 2.841 ± 1.517
1.705TyrPro: 1.705 ± 1.017
2.841TyrGln: 2.841 ± 0.839
3.409TyrArg: 3.409 ± 0.79
5.114TyrSer: 5.114 ± 1.509
1.705TyrThr: 1.705 ± 0.718
2.841TyrVal: 2.841 ± 1.555
0.0TyrTrp: 0.0 ± 0.0
3.409TyrTyr: 3.409 ± 2.041
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (1761 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski