Amino acid dipepetide frequency for Plicaturopsis crispa FD-325 SS-3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.417AlaAla: 10.417 ± 0.175	1.409AlaCys: 1.409 ± 0.044	4.798AlaAsp: 4.798 ± 0.092	5.1AlaGlu: 5.1 ± 0.086	3.518AlaPhe: 3.518 ± 0.063	6.02AlaGly: 6.02 ± 0.095	3.045AlaHis: 3.045 ± 0.076	4.09AlaIle: 4.09 ± 0.067	3.849AlaLys: 3.849 ± 0.079	9.337AlaLeu: 9.337 ± 0.114	1.937AlaMet: 1.937 ± 0.046	2.856AlaAsn: 2.856 ± 0.069	6.648AlaPro: 6.648 ± 0.12	3.646AlaGln: 3.646 ± 0.068	7.213AlaArg: 7.213 ± 0.107	8.203AlaSer: 8.203 ± 0.107	5.633AlaThr: 5.633 ± 0.09	6.045AlaVal: 6.045 ± 0.081	1.398AlaTrp: 1.398 ± 0.037	2.419AlaTyr: 2.419 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	1.422CysAla: 1.422 ± 0.051	0.293CysCys: 0.293 ± 0.02	0.728CysAsp: 0.728 ± 0.025	0.709CysGlu: 0.709 ± 0.028	0.484CysPhe: 0.484 ± 0.021	0.962CysGly: 0.962 ± 0.04	0.381CysHis: 0.381 ± 0.02	0.701CysIle: 0.701 ± 0.029	0.513CysLys: 0.513 ± 0.03	1.354CysLeu: 1.354 ± 0.042	0.326CysMet: 0.326 ± 0.018	0.395CysAsn: 0.395 ± 0.019	1.042CysPro: 1.042 ± 0.04	0.499CysGln: 0.499 ± 0.022	1.016CysArg: 1.016 ± 0.03	1.018CysSer: 1.018 ± 0.036	1.013CysThr: 1.013 ± 0.036	0.967CysVal: 0.967 ± 0.033	0.196CysTrp: 0.196 ± 0.016	0.351CysTyr: 0.351 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	6.076AspAla: 6.076 ± 0.108	0.625AspCys: 0.625 ± 0.025	4.688AspAsp: 4.688 ± 0.101	4.368AspGlu: 4.368 ± 0.089	2.003AspPhe: 2.003 ± 0.047	4.178AspGly: 4.178 ± 0.073	1.237AspHis: 1.237 ± 0.037	2.949AspIle: 2.949 ± 0.063	1.968AspLys: 1.968 ± 0.053	4.649AspLeu: 4.649 ± 0.077	1.236AspMet: 1.236 ± 0.037	1.689AspAsn: 1.689 ± 0.044	3.497AspPro: 3.497 ± 0.063	1.419AspGln: 1.419 ± 0.036	3.021AspArg: 3.021 ± 0.056	3.895AspSer: 3.895 ± 0.072	3.083AspThr: 3.083 ± 0.057	4.075AspVal: 4.075 ± 0.072	0.922AspTrp: 0.922 ± 0.033	1.436AspTyr: 1.436 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	4.89GluAla: 4.89 ± 0.077	0.694GluCys: 0.694 ± 0.028	4.117GluAsp: 4.117 ± 0.093	4.828GluGlu: 4.828 ± 0.126	1.722GluPhe: 1.722 ± 0.046	3.559GluGly: 3.559 ± 0.068	1.464GluHis: 1.464 ± 0.038	2.476GluIle: 2.476 ± 0.051	2.768GluLys: 2.768 ± 0.066	4.717GluLeu: 4.717 ± 0.073	1.283GluMet: 1.283 ± 0.038	1.865GluAsn: 1.865 ± 0.049	2.529GluPro: 2.529 ± 0.06	2.044GluGln: 2.044 ± 0.044	4.251GluArg: 4.251 ± 0.093	3.683GluSer: 3.683 ± 0.063	2.846GluThr: 2.846 ± 0.053	3.177GluVal: 3.177 ± 0.07	0.976GluTrp: 0.976 ± 0.034	1.525GluTyr: 1.525 ± 0.043	0.0GluXaa: 0.0 ± 0.0
Phe	3.294PheAla: 3.294 ± 0.073	0.547PheCys: 0.547 ± 0.024	2.086PheAsp: 2.086 ± 0.051	1.912PheGlu: 1.912 ± 0.046	1.459PhePhe: 1.459 ± 0.043	2.542PheGly: 2.542 ± 0.054	0.908PheHis: 0.908 ± 0.033	1.615PheIle: 1.615 ± 0.048	1.282PheLys: 1.282 ± 0.038	3.239PheLeu: 3.239 ± 0.058	0.746PheMet: 0.746 ± 0.026	1.207PheAsn: 1.207 ± 0.037	2.151PhePro: 2.151 ± 0.051	1.026PheGln: 1.026 ± 0.032	2.059PheArg: 2.059 ± 0.045	2.859PheSer: 2.859 ± 0.05	2.061PheThr: 2.061 ± 0.049	2.472PheVal: 2.472 ± 0.045	0.548PheTrp: 0.548 ± 0.023	0.95PheTyr: 0.95 ± 0.037	0.0PheXaa: 0.0 ± 0.0
Gly	5.638GlyAla: 5.638 ± 0.086	0.964GlyCys: 0.964 ± 0.035	3.465GlyAsp: 3.465 ± 0.07	3.445GlyGlu: 3.445 ± 0.074	2.307GlyPhe: 2.307 ± 0.057	5.436GlyGly: 5.436 ± 0.137	1.751GlyHis: 1.751 ± 0.044	3.029GlyIle: 3.029 ± 0.056	3.115GlyLys: 3.115 ± 0.073	5.435GlyLeu: 5.435 ± 0.083	1.46GlyMet: 1.46 ± 0.052	2.075GlyAsn: 2.075 ± 0.052	3.707GlyPro: 3.707 ± 0.068	2.064GlyGln: 2.064 ± 0.045	4.524GlyArg: 4.524 ± 0.071	5.234GlySer: 5.234 ± 0.093	3.852GlyThr: 3.852 ± 0.07	4.374GlyVal: 4.374 ± 0.064	1.171GlyTrp: 1.171 ± 0.041	1.757GlyTyr: 1.757 ± 0.041	0.0GlyXaa: 0.0 ± 0.0
His	3.005HisAla: 3.005 ± 0.072	0.437HisCys: 0.437 ± 0.021	1.677HisAsp: 1.677 ± 0.048	1.248HisGlu: 1.248 ± 0.033	0.95HisPhe: 0.95 ± 0.028	1.888HisGly: 1.888 ± 0.048	0.961HisHis: 0.961 ± 0.041	1.372HisIle: 1.372 ± 0.046	0.847HisLys: 0.847 ± 0.031	2.636HisLeu: 2.636 ± 0.057	0.527HisMet: 0.527 ± 0.024	0.817HisAsn: 0.817 ± 0.032	2.347HisPro: 2.347 ± 0.05	0.845HisGln: 0.845 ± 0.03	2.171HisArg: 2.171 ± 0.042	2.164HisSer: 2.164 ± 0.052	1.731HisThr: 1.731 ± 0.052	1.721HisVal: 1.721 ± 0.039	0.403HisTrp: 0.403 ± 0.018	0.675HisTyr: 0.675 ± 0.03	0.0HisXaa: 0.0 ± 0.0
Ile	4.263IleAla: 4.263 ± 0.072	0.721IleCys: 0.721 ± 0.027	2.612IleAsp: 2.612 ± 0.065	2.363IleGlu: 2.363 ± 0.054	1.649IlePhe: 1.649 ± 0.05	2.788IleGly: 2.788 ± 0.055	1.155IleHis: 1.155 ± 0.036	2.039IleIle: 2.039 ± 0.051	1.619IleLys: 1.619 ± 0.039	4.146IleLeu: 4.146 ± 0.066	0.89IleMet: 0.89 ± 0.033	1.395IleAsn: 1.395 ± 0.035	3.123IlePro: 3.123 ± 0.053	1.444IleGln: 1.444 ± 0.037	2.704IleArg: 2.704 ± 0.052	3.491IleSer: 3.491 ± 0.059	2.458IleThr: 2.458 ± 0.057	3.022IleVal: 3.022 ± 0.058	0.795IleTrp: 0.795 ± 0.028	1.237IleTyr: 1.237 ± 0.041	0.0IleXaa: 0.0 ± 0.0
Lys	3.94LysAla: 3.94 ± 0.085	0.502LysCys: 0.502 ± 0.024	2.322LysAsp: 2.322 ± 0.056	2.407LysGlu: 2.407 ± 0.061	1.225LysPhe: 1.225 ± 0.039	2.715LysGly: 2.715 ± 0.063	1.069LysHis: 1.069 ± 0.035	1.785LysIle: 1.785 ± 0.052	2.568LysLys: 2.568 ± 0.075	3.453LysLeu: 3.453 ± 0.062	0.809LysMet: 0.809 ± 0.029	1.348LysAsn: 1.348 ± 0.039	2.373LysPro: 2.373 ± 0.067	1.308LysGln: 1.308 ± 0.039	3.348LysArg: 3.348 ± 0.06	2.842LysSer: 2.842 ± 0.054	2.42LysThr: 2.42 ± 0.054	2.232LysVal: 2.232 ± 0.053	0.654LysTrp: 0.654 ± 0.027	1.106LysTyr: 1.106 ± 0.033	0.0LysXaa: 0.0 ± 0.0
Leu	8.76LeuAla: 8.76 ± 0.102	1.366LeuCys: 1.366 ± 0.039	4.992LeuAsp: 4.992 ± 0.084	4.945LeuGlu: 4.945 ± 0.08	3.282LeuPhe: 3.282 ± 0.072	5.409LeuGly: 5.409 ± 0.083	2.647LeuHis: 2.647 ± 0.055	3.421LeuIle: 3.421 ± 0.066	3.521LeuLys: 3.521 ± 0.068	8.039LeuLeu: 8.039 ± 0.111	1.575LeuMet: 1.575 ± 0.044	2.611LeuAsn: 2.611 ± 0.054	6.383LeuPro: 6.383 ± 0.099	3.41LeuGln: 3.41 ± 0.063	6.733LeuArg: 6.733 ± 0.108	7.185LeuSer: 7.185 ± 0.097	4.994LeuThr: 4.994 ± 0.075	5.691LeuVal: 5.691 ± 0.083	1.249LeuTrp: 1.249 ± 0.035	2.289LeuTyr: 2.289 ± 0.046	0.0LeuXaa: 0.0 ± 0.0
Met	1.938MetAla: 1.938 ± 0.04	0.298MetCys: 0.298 ± 0.017	1.237MetAsp: 1.237 ± 0.04	1.067MetGlu: 1.067 ± 0.035	0.646MetPhe: 0.646 ± 0.026	1.218MetGly: 1.218 ± 0.04	0.635MetHis: 0.635 ± 0.028	0.802MetIle: 0.802 ± 0.028	0.805MetLys: 0.805 ± 0.031	1.772MetLeu: 1.772 ± 0.041	0.493MetMet: 0.493 ± 0.024	0.607MetAsn: 0.607 ± 0.026	1.384MetPro: 1.384 ± 0.046	0.809MetGln: 0.809 ± 0.03	1.524MetArg: 1.524 ± 0.038	1.956MetSer: 1.956 ± 0.044	1.129MetThr: 1.129 ± 0.034	1.077MetVal: 1.077 ± 0.034	0.274MetTrp: 0.274 ± 0.018	0.523MetTyr: 0.523 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	3.334AsnAla: 3.334 ± 0.084	0.385AsnCys: 0.385 ± 0.019	1.714AsnAsp: 1.714 ± 0.047	1.578AsnGlu: 1.578 ± 0.04	1.113AsnPhe: 1.113 ± 0.032	2.347AsnGly: 2.347 ± 0.062	0.741AsnHis: 0.741 ± 0.027	1.663AsnIle: 1.663 ± 0.042	1.099AsnLys: 1.099 ± 0.036	2.662AsnLeu: 2.662 ± 0.056	0.717AsnMet: 0.717 ± 0.027	1.037AsnAsn: 1.037 ± 0.034	2.096AsnPro: 2.096 ± 0.05	0.824AsnGln: 0.824 ± 0.031	1.757AsnArg: 1.757 ± 0.042	2.199AsnSer: 2.199 ± 0.049	1.862AsnThr: 1.862 ± 0.049	2.172AsnVal: 2.172 ± 0.05	0.466AsnTrp: 0.466 ± 0.023	0.82AsnTyr: 0.82 ± 0.033	0.0AsnXaa: 0.0 ± 0.0
Pro	7.157ProAla: 7.157 ± 0.119	0.844ProCys: 0.844 ± 0.04	3.427ProAsp: 3.427 ± 0.066	3.45ProGlu: 3.45 ± 0.068	2.175ProPhe: 2.175 ± 0.047	4.012ProGly: 4.012 ± 0.071	2.132ProHis: 2.132 ± 0.054	2.49ProIle: 2.49 ± 0.051	2.234ProLys: 2.234 ± 0.047	5.461ProLeu: 5.461 ± 0.08	1.104ProMet: 1.104 ± 0.035	2.044ProAsn: 2.044 ± 0.05	7.882ProPro: 7.882 ± 0.236	2.404ProGln: 2.404 ± 0.065	5.058ProArg: 5.058 ± 0.101	7.572ProSer: 7.572 ± 0.165	4.626ProThr: 4.626 ± 0.084	3.857ProVal: 3.857 ± 0.065	0.859ProTrp: 0.859 ± 0.03	1.593ProTyr: 1.593 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	3.155GlnAla: 3.155 ± 0.064	0.511GlnCys: 0.511 ± 0.027	1.852GlnAsp: 1.852 ± 0.051	1.835GlnGlu: 1.835 ± 0.046	1.158GlnPhe: 1.158 ± 0.038	2.145GlnGly: 2.145 ± 0.049	1.047GlnHis: 1.047 ± 0.032	1.474GlnIle: 1.474 ± 0.038	1.4GlnLys: 1.4 ± 0.041	2.968GlnLeu: 2.968 ± 0.055	0.77GlnMet: 0.77 ± 0.028	1.111GlnAsn: 1.111 ± 0.04	2.366GlnPro: 2.366 ± 0.061	1.569GlnGln: 1.569 ± 0.084	2.777GlnArg: 2.777 ± 0.063	2.636GlnSer: 2.636 ± 0.061	1.999GlnThr: 1.999 ± 0.05	1.929GlnVal: 1.929 ± 0.047	0.586GlnTrp: 0.586 ± 0.023	0.96GlnTyr: 0.96 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	7.244ArgAla: 7.244 ± 0.1	1.178ArgCys: 1.178 ± 0.044	3.757ArgAsp: 3.757 ± 0.061	4.065ArgGlu: 4.065 ± 0.076	2.17ArgPhe: 2.17 ± 0.047	4.049ArgGly: 4.049 ± 0.071	2.072ArgHis: 2.072 ± 0.049	3.139ArgIle: 3.139 ± 0.057	3.346ArgLys: 3.346 ± 0.068	6.181ArgLeu: 6.181 ± 0.099	1.496ArgMet: 1.496 ± 0.043	1.974ArgAsn: 1.974 ± 0.05	4.614ArgPro: 4.614 ± 0.116	2.592ArgGln: 2.592 ± 0.053	7.089ArgArg: 7.089 ± 0.139	5.378ArgSer: 5.378 ± 0.092	4.408ArgThr: 4.408 ± 0.073	4.409ArgVal: 4.409 ± 0.087	1.158ArgTrp: 1.158 ± 0.033	1.723ArgTyr: 1.723 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	7.914SerAla: 7.914 ± 0.117	1.086SerCys: 1.086 ± 0.04	4.118SerAsp: 4.118 ± 0.074	3.665SerGlu: 3.665 ± 0.073	2.889SerPhe: 2.889 ± 0.059	5.309SerGly: 5.309 ± 0.088	2.197SerHis: 2.197 ± 0.061	3.565SerIle: 3.565 ± 0.065	3.047SerLys: 3.047 ± 0.066	7.016SerLeu: 7.016 ± 0.091	1.604SerMet: 1.604 ± 0.043	2.472SerAsn: 2.472 ± 0.057	6.305SerPro: 6.305 ± 0.138	2.789SerGln: 2.789 ± 0.068	5.671SerArg: 5.671 ± 0.096	9.355SerSer: 9.355 ± 0.183	6.074SerThr: 6.074 ± 0.098	4.753SerVal: 4.753 ± 0.067	1.081SerTrp: 1.081 ± 0.034	1.789SerTyr: 1.789 ± 0.047	0.0SerXaa: 0.0 ± 0.0
Thr	5.858ThrAla: 5.858 ± 0.084	0.777ThrCys: 0.777 ± 0.028	2.979ThrAsp: 2.979 ± 0.058	2.615ThrGlu: 2.615 ± 0.051	2.171ThrPhe: 2.171 ± 0.056	3.728ThrGly: 3.728 ± 0.072	1.809ThrHis: 1.809 ± 0.042	2.614ThrIle: 2.614 ± 0.049	2.21ThrLys: 2.21 ± 0.054	5.517ThrLeu: 5.517 ± 0.079	1.126ThrMet: 1.126 ± 0.032	1.745ThrAsn: 1.745 ± 0.046	5.25ThrPro: 5.25 ± 0.098	1.891ThrGln: 1.891 ± 0.045	4.158ThrArg: 4.158 ± 0.074	5.3ThrSer: 5.3 ± 0.091	4.334ThrThr: 4.334 ± 0.082	3.931ThrVal: 3.931 ± 0.069	0.807ThrTrp: 0.807 ± 0.029	1.557ThrTyr: 1.557 ± 0.041	0.0ThrXaa: 0.0 ± 0.0
Val	5.61ValAla: 5.61 ± 0.082	1.051ValCys: 1.051 ± 0.032	3.839ValAsp: 3.839 ± 0.062	3.619ValGlu: 3.619 ± 0.064	2.388ValPhe: 2.388 ± 0.053	3.753ValGly: 3.753 ± 0.079	1.948ValHis: 1.948 ± 0.046	2.694ValIle: 2.694 ± 0.055	2.514ValLys: 2.514 ± 0.056	6.152ValLeu: 6.152 ± 0.094	1.172ValMet: 1.172 ± 0.033	1.927ValAsn: 1.927 ± 0.051	4.313ValPro: 4.313 ± 0.067	2.347ValGln: 2.347 ± 0.05	4.217ValArg: 4.217 ± 0.068	4.817ValSer: 4.817 ± 0.075	3.274ValThr: 3.274 ± 0.064	4.655ValVal: 4.655 ± 0.079	0.996ValTrp: 0.996 ± 0.032	1.825ValTyr: 1.825 ± 0.048	0.0ValXaa: 0.0 ± 0.0
Trp	1.279TrpAla: 1.279 ± 0.036	0.27TrpCys: 0.27 ± 0.017	0.95TrpAsp: 0.95 ± 0.034	0.844TrpGlu: 0.844 ± 0.03	0.562TrpPhe: 0.562 ± 0.025	0.924TrpGly: 0.924 ± 0.037	0.438TrpHis: 0.438 ± 0.018	0.794TrpIle: 0.794 ± 0.03	0.768TrpLys: 0.768 ± 0.03	1.413TrpLeu: 1.413 ± 0.04	0.378TrpMet: 0.378 ± 0.019	0.502TrpAsn: 0.502 ± 0.025	0.717TrpPro: 0.717 ± 0.026	0.531TrpGln: 0.531 ± 0.022	1.118TrpArg: 1.118 ± 0.038	1.086TrpSer: 1.086 ± 0.035	0.994TrpThr: 0.994 ± 0.034	0.939TrpVal: 0.939 ± 0.034	0.294TrpTrp: 0.294 ± 0.02	0.418TrpTyr: 0.418 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.39TyrAla: 2.39 ± 0.045	0.413TyrCys: 0.413 ± 0.022	1.655TyrAsp: 1.655 ± 0.044	1.352TyrGlu: 1.352 ± 0.036	1.092TyrPhe: 1.092 ± 0.04	1.822TyrGly: 1.822 ± 0.045	0.785TyrHis: 0.785 ± 0.029	1.203TyrIle: 1.203 ± 0.038	0.953TyrLys: 0.953 ± 0.031	2.354TyrLeu: 2.354 ± 0.055	0.544TyrMet: 0.544 ± 0.024	0.911TyrAsn: 0.911 ± 0.027	1.654TyrPro: 1.654 ± 0.049	0.784TyrGln: 0.784 ± 0.028	1.633TyrArg: 1.633 ± 0.04	1.826TyrSer: 1.826 ± 0.043	1.587TyrThr: 1.587 ± 0.042	1.613TyrVal: 1.613 ± 0.048	0.384TyrTrp: 0.384 ± 0.019	0.778TyrTyr: 0.778 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2710 proteins (993639 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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