Amino acid dipepetide frequency for Myripristis murdjan (pinecone soldierfish)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.175AlaAla: 6.175 ± 0.023
1.365AlaCys: 1.365 ± 0.008
3.21AlaAsp: 3.21 ± 0.009
4.651AlaGlu: 4.651 ± 0.018
2.52AlaPhe: 2.52 ± 0.01
4.385AlaGly: 4.385 ± 0.016
1.577AlaHis: 1.577 ± 0.007
2.898AlaIle: 2.898 ± 0.01
3.513AlaLys: 3.513 ± 0.012
6.846AlaLeu: 6.846 ± 0.019
1.702AlaMet: 1.702 ± 0.007
2.247AlaAsn: 2.247 ± 0.008
3.337AlaPro: 3.337 ± 0.015
2.999AlaGln: 2.999 ± 0.014
3.227AlaArg: 3.227 ± 0.011
5.242AlaSer: 5.242 ± 0.015
3.503AlaThr: 3.503 ± 0.013
5.105AlaVal: 5.105 ± 0.016
0.699AlaTrp: 0.699 ± 0.005
1.654AlaTyr: 1.654 ± 0.007
0.0AlaXaa: 0.0 ± 0.0
Cys
1.263CysAla: 1.263 ± 0.008
0.676CysCys: 0.676 ± 0.006
1.15CysAsp: 1.15 ± 0.009
1.241CysGlu: 1.241 ± 0.009
0.994CysPhe: 0.994 ± 0.006
1.545CysGly: 1.545 ± 0.011
0.699CysHis: 0.699 ± 0.005
1.085CysIle: 1.085 ± 0.007
1.153CysLys: 1.153 ± 0.007
2.402CysLeu: 2.402 ± 0.012
0.512CysMet: 0.512 ± 0.004
0.825CysAsn: 0.825 ± 0.006
1.281CysPro: 1.281 ± 0.009
1.065CysGln: 1.065 ± 0.008
1.316CysArg: 1.316 ± 0.008
2.115CysSer: 2.115 ± 0.012
1.207CysThr: 1.207 ± 0.007
1.886CysVal: 1.886 ± 0.014
0.313CysTrp: 0.313 ± 0.003
0.662CysTyr: 0.662 ± 0.005
0.0CysXaa: 0.0 ± 0.0
Asp
3.019AspAla: 3.019 ± 0.011
1.155AspCys: 1.155 ± 0.008
2.994AspAsp: 2.994 ± 0.016
3.624AspGlu: 3.624 ± 0.015
2.208AspPhe: 2.208 ± 0.008
3.558AspGly: 3.558 ± 0.013
1.22AspHis: 1.22 ± 0.007
2.835AspIle: 2.835 ± 0.011
2.794AspLys: 2.794 ± 0.011
5.056AspLeu: 5.056 ± 0.014
1.36AspMet: 1.36 ± 0.007
1.962AspAsn: 1.962 ± 0.009
2.84AspPro: 2.84 ± 0.01
1.942AspGln: 1.942 ± 0.009
2.756AspArg: 2.756 ± 0.011
4.191AspSer: 4.191 ± 0.014
2.63AspThr: 2.63 ± 0.009
3.365AspVal: 3.365 ± 0.011
0.725AspTrp: 0.725 ± 0.005
1.639AspTyr: 1.639 ± 0.008
0.0AspXaa: 0.0 ± 0.0
Glu
4.876GluAla: 4.876 ± 0.016
1.274GluCys: 1.274 ± 0.01
4.202GluAsp: 4.202 ± 0.015
7.332GluGlu: 7.332 ± 0.034
2.064GluPhe: 2.064 ± 0.009
4.14GluGly: 4.14 ± 0.015
1.458GluHis: 1.458 ± 0.007
2.92GluIle: 2.92 ± 0.011
4.525GluLys: 4.525 ± 0.02
6.397GluLeu: 6.397 ± 0.023
1.752GluMet: 1.752 ± 0.009
2.641GluAsn: 2.641 ± 0.01
2.618GluPro: 2.618 ± 0.011
3.069GluGln: 3.069 ± 0.013
4.266GluArg: 4.266 ± 0.019
4.023GluSer: 4.023 ± 0.013
3.242GluThr: 3.242 ± 0.012
4.354GluVal: 4.354 ± 0.014
0.715GluTrp: 0.715 ± 0.005
1.707GluTyr: 1.707 ± 0.008
0.0GluXaa: 0.0 ± 0.0
Phe
2.054PheAla: 2.054 ± 0.008
1.026PheCys: 1.026 ± 0.007
1.896PheAsp: 1.896 ± 0.009
1.97PheGlu: 1.97 ± 0.009
1.827PhePhe: 1.827 ± 0.01
2.3PheGly: 2.3 ± 0.01
1.08PheHis: 1.08 ± 0.006
2.068PheIle: 2.068 ± 0.009
1.895PheLys: 1.895 ± 0.008
4.188PheLeu: 4.188 ± 0.015
0.858PheMet: 0.858 ± 0.006
1.546PheAsn: 1.546 ± 0.008
1.898PhePro: 1.898 ± 0.009
1.693PheGln: 1.693 ± 0.008
1.904PheArg: 1.904 ± 0.007
3.457PheSer: 3.457 ± 0.012
2.401PheThr: 2.401 ± 0.011
2.388PheVal: 2.388 ± 0.01
0.488PheTrp: 0.488 ± 0.004
1.314PheTyr: 1.314 ± 0.006
0.0PheXaa: 0.0 ± 0.0
Gly
4.06GlyAla: 4.06 ± 0.015
1.276GlyCys: 1.276 ± 0.007
3.22GlyAsp: 3.22 ± 0.011
4.096GlyGlu: 4.096 ± 0.014
2.486GlyPhe: 2.486 ± 0.01
5.24GlyGly: 5.24 ± 0.024
1.689GlyHis: 1.689 ± 0.009
2.676GlyIle: 2.676 ± 0.01
3.676GlyLys: 3.676 ± 0.014
5.575GlyLeu: 5.575 ± 0.015
1.518GlyMet: 1.518 ± 0.007
2.42GlyAsn: 2.42 ± 0.009
3.053GlyPro: 3.053 ± 0.022
2.775GlyGln: 2.775 ± 0.012
3.637GlyArg: 3.637 ± 0.012
5.313GlySer: 5.313 ± 0.016
3.439GlyThr: 3.439 ± 0.014
4.06GlyVal: 4.06 ± 0.013
0.797GlyTrp: 0.797 ± 0.006
1.918GlyTyr: 1.918 ± 0.01
0.0GlyXaa: 0.0 ± 0.0
His
1.41HisAla: 1.41 ± 0.007
0.795HisCys: 0.795 ± 0.006
1.027HisAsp: 1.027 ± 0.007
1.237HisGlu: 1.237 ± 0.007
1.147HisPhe: 1.147 ± 0.006
1.587HisGly: 1.587 ± 0.008
1.0HisHis: 1.0 ± 0.008
1.415HisIle: 1.415 ± 0.007
1.324HisLys: 1.324 ± 0.007
2.773HisLeu: 2.773 ± 0.011
0.707HisMet: 0.707 ± 0.006
1.05HisAsn: 1.05 ± 0.006
1.549HisPro: 1.549 ± 0.008
1.214HisGln: 1.214 ± 0.007
1.642HisArg: 1.642 ± 0.008
2.354HisSer: 2.354 ± 0.011
1.897HisThr: 1.897 ± 0.012
1.511HisVal: 1.511 ± 0.007
0.351HisTrp: 0.351 ± 0.004
0.909HisTyr: 0.909 ± 0.005
0.0HisXaa: 0.0 ± 0.0
Ile
2.715IleAla: 2.715 ± 0.011
1.118IleCys: 1.118 ± 0.007
2.27IleAsp: 2.27 ± 0.01
2.502IleGlu: 2.502 ± 0.009
1.941IlePhe: 1.941 ± 0.009
2.399IleGly: 2.399 ± 0.01
1.375IleHis: 1.375 ± 0.007
2.533IleIle: 2.533 ± 0.012
2.649IleLys: 2.649 ± 0.011
4.523IleLeu: 4.523 ± 0.016
1.146IleMet: 1.146 ± 0.006
2.035IleAsn: 2.035 ± 0.008
2.467IlePro: 2.467 ± 0.01
2.257IleGln: 2.257 ± 0.009
2.553IleArg: 2.553 ± 0.009
3.748IleSer: 3.748 ± 0.011
2.833IleThr: 2.833 ± 0.012
2.716IleVal: 2.716 ± 0.012
0.491IleTrp: 0.491 ± 0.005
1.505IleTyr: 1.505 ± 0.008
0.0IleXaa: 0.0 ± 0.0
Lys
3.863LysAla: 3.863 ± 0.012
1.032LysCys: 1.032 ± 0.007
3.203LysAsp: 3.203 ± 0.012
4.574LysGlu: 4.574 ± 0.019
1.73LysPhe: 1.73 ± 0.008
3.18LysGly: 3.18 ± 0.011
1.425LysHis: 1.425 ± 0.008
2.599LysIle: 2.599 ± 0.011
4.301LysLys: 4.301 ± 0.022
5.168LysLeu: 5.168 ± 0.017
1.485LysMet: 1.485 ± 0.007
2.309LysAsn: 2.309 ± 0.01
2.722LysPro: 2.722 ± 0.012
2.549LysGln: 2.549 ± 0.013
3.312LysArg: 3.312 ± 0.012
3.568LysSer: 3.568 ± 0.013
3.116LysThr: 3.116 ± 0.011
3.654LysVal: 3.654 ± 0.011
0.598LysTrp: 0.598 ± 0.005
1.574LysTyr: 1.574 ± 0.007
0.0LysXaa: 0.0 ± 0.0
Leu
6.54LeuAla: 6.54 ± 0.017
2.452LeuCys: 2.452 ± 0.012
5.04LeuAsp: 5.04 ± 0.013
6.546LeuGlu: 6.546 ± 0.025
3.743LeuPhe: 3.743 ± 0.013
5.363LeuGly: 5.363 ± 0.015
2.85LeuHis: 2.85 ± 0.012
4.07LeuIle: 4.07 ± 0.012
5.683LeuLys: 5.683 ± 0.016
10.636LeuLeu: 10.636 ± 0.032
2.207LeuMet: 2.207 ± 0.009
3.643LeuAsn: 3.643 ± 0.011
5.272LeuPro: 5.272 ± 0.016
5.558LeuGln: 5.558 ± 0.02
5.781LeuArg: 5.781 ± 0.016
8.35LeuSer: 8.35 ± 0.02
5.346LeuThr: 5.346 ± 0.014
5.755LeuVal: 5.755 ± 0.018
1.132LeuTrp: 1.132 ± 0.006
2.805LeuTyr: 2.805 ± 0.01
0.0LeuXaa: 0.0 ± 0.0
Met
1.964MetAla: 1.964 ± 0.008
0.531MetCys: 0.531 ± 0.004
1.453MetAsp: 1.453 ± 0.007
1.997MetGlu: 1.997 ± 0.008
0.913MetPhe: 0.913 ± 0.005
1.459MetGly: 1.459 ± 0.007
0.526MetHis: 0.526 ± 0.004
0.941MetIle: 0.941 ± 0.006
1.52MetLys: 1.52 ± 0.007
2.221MetLeu: 2.221 ± 0.01
0.722MetMet: 0.722 ± 0.006
0.941MetAsn: 0.941 ± 0.006
1.097MetPro: 1.097 ± 0.007
1.009MetGln: 1.009 ± 0.005
1.252MetArg: 1.252 ± 0.007
1.776MetSer: 1.776 ± 0.007
1.283MetThr: 1.283 ± 0.007
1.639MetVal: 1.639 ± 0.007
0.273MetTrp: 0.273 ± 0.003
0.681MetTyr: 0.681 ± 0.004
0.0MetXaa: 0.0 ± 0.0
Asn
2.193AsnAla: 2.193 ± 0.009
0.873AsnCys: 0.873 ± 0.006
1.693AsnAsp: 1.693 ± 0.01
2.056AsnGlu: 2.056 ± 0.009
1.472AsnPhe: 1.472 ± 0.008
2.685AsnGly: 2.685 ± 0.011
1.006AsnHis: 1.006 ± 0.006
2.222AsnIle: 2.222 ± 0.009
2.203AsnLys: 2.203 ± 0.008
3.716AsnLeu: 3.716 ± 0.013
1.065AsnMet: 1.065 ± 0.006
1.763AsnAsn: 1.763 ± 0.009
2.265AsnPro: 2.265 ± 0.009
1.686AsnGln: 1.686 ± 0.007
1.953AsnArg: 1.953 ± 0.008
2.989AsnSer: 2.989 ± 0.01
2.245AsnThr: 2.245 ± 0.009
2.272AsnVal: 2.272 ± 0.009
0.469AsnTrp: 0.469 ± 0.004
1.195AsnTyr: 1.195 ± 0.007
0.0AsnXaa: 0.0 ± 0.0
Pro
3.967ProAla: 3.967 ± 0.015
1.09ProCys: 1.09 ± 0.009
2.836ProAsp: 2.836 ± 0.011
3.669ProGlu: 3.669 ± 0.015
1.852ProPhe: 1.852 ± 0.009
3.836ProGly: 3.836 ± 0.023
1.482ProHis: 1.482 ± 0.009
1.873ProIle: 1.873 ± 0.008
2.406ProLys: 2.406 ± 0.013
4.784ProLeu: 4.784 ± 0.016
1.023ProMet: 1.023 ± 0.007
1.87ProAsn: 1.87 ± 0.008
4.837ProPro: 4.837 ± 0.03
2.482ProGln: 2.482 ± 0.015
2.583ProArg: 2.583 ± 0.012
5.006ProSer: 5.006 ± 0.019
2.82ProThr: 2.82 ± 0.011
3.646ProVal: 3.646 ± 0.013
0.571ProTrp: 0.571 ± 0.005
1.43ProTyr: 1.43 ± 0.008
0.0ProXaa: 0.0 ± 0.0
Gln
3.32GlnAla: 3.32 ± 0.013
1.012GlnCys: 1.012 ± 0.008
2.308GlnAsp: 2.308 ± 0.01
3.447GlnGlu: 3.447 ± 0.014
1.47GlnPhe: 1.47 ± 0.007
2.767GlnGly: 2.767 ± 0.011
1.369GlnHis: 1.369 ± 0.007
1.997GlnIle: 1.997 ± 0.008
2.508GlnLys: 2.508 ± 0.012
4.633GlnLeu: 4.633 ± 0.014
1.154GlnMet: 1.154 ± 0.007
1.675GlnAsn: 1.675 ± 0.008
2.432GlnPro: 2.432 ± 0.013
3.159GlnGln: 3.159 ± 0.026
3.053GlnArg: 3.053 ± 0.012
3.228GlnSer: 3.228 ± 0.013
2.445GlnThr: 2.445 ± 0.009
2.904GlnVal: 2.904 ± 0.011
0.584GlnTrp: 0.584 ± 0.004
1.316GlnTyr: 1.316 ± 0.006
0.0GlnXaa: 0.0 ± 0.0
Arg
3.534ArgAla: 3.534 ± 0.011
1.29ArgCys: 1.29 ± 0.009
3.011ArgAsp: 3.011 ± 0.011
3.909ArgGlu: 3.909 ± 0.016
2.076ArgPhe: 2.076 ± 0.009
3.395ArgGly: 3.395 ± 0.017
1.572ArgHis: 1.572 ± 0.007
2.506ArgIle: 2.506 ± 0.01
3.437ArgLys: 3.437 ± 0.013
5.528ArgLeu: 5.528 ± 0.016
1.324ArgMet: 1.324 ± 0.007
2.132ArgAsn: 2.132 ± 0.01
2.799ArgPro: 2.799 ± 0.012
2.702ArgGln: 2.702 ± 0.011
4.144ArgArg: 4.144 ± 0.015
4.154ArgSer: 4.154 ± 0.015
2.811ArgThr: 2.811 ± 0.009
3.356ArgVal: 3.356 ± 0.01
0.705ArgTrp: 0.705 ± 0.006
1.646ArgTyr: 1.646 ± 0.007
0.0ArgXaa: 0.0 ± 0.0
Ser
5.285SerAla: 5.285 ± 0.015
1.95SerCys: 1.95 ± 0.011
4.084SerAsp: 4.084 ± 0.015
4.56SerGlu: 4.56 ± 0.013
3.074SerPhe: 3.074 ± 0.011
5.304SerGly: 5.304 ± 0.015
2.17SerHis: 2.17 ± 0.009
3.336SerIle: 3.336 ± 0.012
3.805SerLys: 3.805 ± 0.012
8.254SerLeu: 8.254 ± 0.02
1.77SerMet: 1.77 ± 0.007
2.813SerAsn: 2.813 ± 0.011
5.205SerPro: 5.205 ± 0.02
3.648SerGln: 3.648 ± 0.013
4.267SerArg: 4.267 ± 0.014
8.934SerSer: 8.934 ± 0.029
4.422SerThr: 4.422 ± 0.015
5.334SerVal: 5.334 ± 0.015
0.972SerTrp: 0.972 ± 0.006
2.166SerTyr: 2.166 ± 0.009
0.0SerXaa: 0.0 ± 0.0
Thr
4.01ThrAla: 4.01 ± 0.013
1.349ThrCys: 1.349 ± 0.01
2.846ThrAsp: 2.846 ± 0.01
3.592ThrGlu: 3.592 ± 0.012
2.175ThrPhe: 2.175 ± 0.01
3.73ThrGly: 3.73 ± 0.014
1.643ThrHis: 1.643 ± 0.011
2.485ThrIle: 2.485 ± 0.01
2.637ThrLys: 2.637 ± 0.01
5.505ThrLeu: 5.505 ± 0.014
1.22ThrMet: 1.22 ± 0.006
1.883ThrAsn: 1.883 ± 0.007
3.412ThrPro: 3.412 ± 0.015
2.349ThrGln: 2.349 ± 0.008
2.457ThrArg: 2.457 ± 0.011
4.376ThrSer: 4.376 ± 0.015
3.08ThrThr: 3.08 ± 0.017
4.215ThrVal: 4.215 ± 0.015
0.666ThrTrp: 0.666 ± 0.005
1.505ThrTyr: 1.505 ± 0.008
0.0ThrXaa: 0.0 ± 0.0
Val
4.327ValAla: 4.327 ± 0.013
2.1ValCys: 2.1 ± 0.012
3.268ValAsp: 3.268 ± 0.012
4.107ValGlu: 4.107 ± 0.012
2.8ValPhe: 2.8 ± 0.012
3.597ValGly: 3.597 ± 0.013
1.621ValHis: 1.621 ± 0.007
3.149ValIle: 3.149 ± 0.012
3.647ValLys: 3.647 ± 0.012
6.439ValLeu: 6.439 ± 0.017
1.595ValMet: 1.595 ± 0.007
2.502ValAsn: 2.502 ± 0.01
3.21ValPro: 3.21 ± 0.011
2.798ValGln: 2.798 ± 0.01
3.444ValArg: 3.444 ± 0.011
5.23ValSer: 5.23 ± 0.015
3.988ValThr: 3.988 ± 0.013
4.534ValVal: 4.534 ± 0.014
0.815ValTrp: 0.815 ± 0.005
1.953ValTyr: 1.953 ± 0.008
0.0ValXaa: 0.0 ± 0.0
Trp
0.736TrpAla: 0.736 ± 0.005
0.276TrpCys: 0.276 ± 0.003
0.694TrpAsp: 0.694 ± 0.005
0.777TrpGlu: 0.777 ± 0.006
0.463TrpPhe: 0.463 ± 0.004
0.651TrpGly: 0.651 ± 0.005
0.29TrpHis: 0.29 ± 0.003
0.587TrpIle: 0.587 ± 0.005
0.722TrpLys: 0.722 ± 0.005
1.226TrpLeu: 1.226 ± 0.008
0.351TrpMet: 0.351 ± 0.003
0.516TrpAsn: 0.516 ± 0.004
0.444TrpPro: 0.444 ± 0.004
0.517TrpGln: 0.517 ± 0.004
0.766TrpArg: 0.766 ± 0.005
0.95TrpSer: 0.95 ± 0.006
0.704TrpThr: 0.704 ± 0.005
0.739TrpVal: 0.739 ± 0.005
0.212TrpTrp: 0.212 ± 0.003
0.363TrpTyr: 0.363 ± 0.003
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.544TyrAla: 1.544 ± 0.007
0.752TyrCys: 0.752 ± 0.005
1.47TyrAsp: 1.47 ± 0.009
1.687TyrGlu: 1.687 ± 0.007
1.297TyrPhe: 1.297 ± 0.006
1.799TyrGly: 1.799 ± 0.01
0.845TyrHis: 0.845 ± 0.005
1.581TyrIle: 1.581 ± 0.007
1.566TyrLys: 1.566 ± 0.009
2.902TyrLeu: 2.902 ± 0.01
0.728TyrMet: 0.728 ± 0.005
1.251TyrAsn: 1.251 ± 0.007
1.326TyrPro: 1.326 ± 0.008
1.311TyrGln: 1.311 ± 0.006
1.718TyrArg: 1.718 ± 0.009
2.348TyrSer: 2.348 ± 0.008
1.722TyrThr: 1.722 ± 0.008
1.691TyrVal: 1.691 ± 0.007
0.407TyrTrp: 0.407 ± 0.005
1.072TyrTyr: 1.072 ± 0.006
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.012XaaXaa: 0.012 ± 0.007
Statistics based on 55955 proteins (34307100 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski