Amino acid dipepetide frequency for Turnip vein-clearing virus (TVCV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.411AlaAla: 7.411 ± 2.092
0.494AlaCys: 0.494 ± 0.234
3.458AlaAsp: 3.458 ± 1.641
5.929AlaGlu: 5.929 ± 2.112
2.964AlaPhe: 2.964 ± 0.647
4.447AlaGly: 4.447 ± 1.194
1.482AlaHis: 1.482 ± 0.736
3.953AlaIle: 3.953 ± 0.544
3.953AlaLys: 3.953 ± 1.25
7.905AlaLeu: 7.905 ± 2.562
3.458AlaMet: 3.458 ± 1.112
2.964AlaAsn: 2.964 ± 1.056
1.482AlaPro: 1.482 ± 1.076
0.988AlaGln: 0.988 ± 0.469
1.976AlaArg: 1.976 ± 1.016
4.447AlaSer: 4.447 ± 1.436
2.964AlaThr: 2.964 ± 3.538
9.881AlaVal: 9.881 ± 2.022
0.988AlaTrp: 0.988 ± 0.469
2.47AlaTyr: 2.47 ± 1.172
0.0AlaXaa: 0.0 ± 0.0
Cys
1.482CysAla: 1.482 ± 0.703
0.988CysCys: 0.988 ± 0.469
3.953CysAsp: 3.953 ± 0.942
0.988CysGlu: 0.988 ± 0.469
0.494CysPhe: 0.494 ± 0.234
1.482CysGly: 1.482 ± 0.703
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
2.47CysLys: 2.47 ± 1.172
0.988CysLeu: 0.988 ± 0.469
0.988CysMet: 0.988 ± 1.179
0.0CysAsn: 0.0 ± 0.0
0.988CysPro: 0.988 ± 0.469
0.494CysGln: 0.494 ± 0.234
0.988CysArg: 0.988 ± 0.469
0.988CysSer: 0.988 ± 0.469
0.988CysThr: 0.988 ± 0.469
1.482CysVal: 1.482 ± 0.736
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.435AspAla: 5.435 ± 0.544
1.482AspCys: 1.482 ± 0.703
1.976AspAsp: 1.976 ± 1.016
4.941AspGlu: 4.941 ± 1.339
3.458AspPhe: 3.458 ± 1.345
1.482AspGly: 1.482 ± 0.703
0.0AspHis: 0.0 ± 0.0
4.941AspIle: 4.941 ± 1.183
5.435AspLys: 5.435 ± 1.218
5.929AspLeu: 5.929 ± 1.295
2.964AspMet: 2.964 ± 1.406
2.47AspAsn: 2.47 ± 0.592
2.47AspPro: 2.47 ± 0.592
0.0AspGln: 0.0 ± 0.0
1.482AspArg: 1.482 ± 0.703
4.941AspSer: 4.941 ± 1.183
4.447AspThr: 4.447 ± 3.227
5.929AspVal: 5.929 ± 1.295
0.494AspTrp: 0.494 ± 0.234
1.482AspTyr: 1.482 ± 0.703
0.0AspXaa: 0.0 ± 0.0
Glu
4.447GluAla: 4.447 ± 1.86
0.494GluCys: 0.494 ± 1.083
1.976GluAsp: 1.976 ± 0.937
6.423GluGlu: 6.423 ± 2.558
4.941GluPhe: 4.941 ± 0.431
3.458GluGly: 3.458 ± 1.345
0.494GluHis: 0.494 ± 0.234
4.941GluIle: 4.941 ± 1.339
5.435GluLys: 5.435 ± 1.218
5.929GluLeu: 5.929 ± 1.999
1.482GluMet: 1.482 ± 0.703
2.47GluAsn: 2.47 ± 0.592
1.976GluPro: 1.976 ± 1.354
1.482GluGln: 1.482 ± 0.703
1.976GluArg: 1.976 ± 0.625
5.435GluSer: 5.435 ± 0.809
2.47GluThr: 2.47 ± 1.133
3.953GluVal: 3.953 ± 0.544
1.482GluTrp: 1.482 ± 0.736
2.47GluTyr: 2.47 ± 1.172
0.0GluXaa: 0.0 ± 0.0
Phe
2.47PheAla: 2.47 ± 1.009
1.482PheCys: 1.482 ± 0.703
2.964PheAsp: 2.964 ± 1.056
2.47PheGlu: 2.47 ± 1.133
2.964PhePhe: 2.964 ± 1.406
1.482PheGly: 1.482 ± 0.703
2.47PheHis: 2.47 ± 1.172
1.482PheIle: 1.482 ± 0.703
3.458PheLys: 3.458 ± 1.345
4.447PheLeu: 4.447 ± 1.134
0.0PheMet: 0.0 ± 0.0
1.482PheAsn: 1.482 ± 0.736
2.47PhePro: 2.47 ± 1.009
2.964PheGln: 2.964 ± 0.647
2.964PheArg: 2.964 ± 0.647
5.435PheSer: 5.435 ± 1.801
2.47PheThr: 2.47 ± 0.592
5.435PheVal: 5.435 ± 1.965
0.988PheTrp: 0.988 ± 0.469
1.482PheTyr: 1.482 ± 0.703
0.0PheXaa: 0.0 ± 0.0
Gly
2.964GlyAla: 2.964 ± 0.647
1.482GlyCys: 1.482 ± 0.703
2.47GlyAsp: 2.47 ± 1.172
1.976GlyGlu: 1.976 ± 0.625
1.482GlyPhe: 1.482 ± 0.736
3.458GlyGly: 3.458 ± 0.773
1.976GlyHis: 1.976 ± 1.016
0.988GlyIle: 0.988 ± 0.896
2.964GlyLys: 2.964 ± 1.406
2.47GlyLeu: 2.47 ± 0.592
0.494GlyMet: 0.494 ± 0.234
1.482GlyAsn: 1.482 ± 0.703
1.482GlyPro: 1.482 ± 0.736
0.494GlyGln: 0.494 ± 0.234
2.964GlyArg: 2.964 ± 0.647
3.458GlySer: 3.458 ± 1.149
2.47GlyThr: 2.47 ± 0.592
6.423GlyVal: 6.423 ± 1.812
0.494GlyTrp: 0.494 ± 1.083
1.482GlyTyr: 1.482 ± 1.076
0.0GlyXaa: 0.0 ± 0.0
His
0.494HisAla: 0.494 ± 0.234
1.482HisCys: 1.482 ± 0.703
0.494HisAsp: 0.494 ± 0.234
1.482HisGlu: 1.482 ± 0.703
1.976HisPhe: 1.976 ± 0.937
0.988HisGly: 0.988 ± 1.179
0.494HisHis: 0.494 ± 0.234
0.988HisIle: 0.988 ± 0.469
2.47HisLys: 2.47 ± 1.172
1.482HisLeu: 1.482 ± 0.703
0.494HisMet: 0.494 ± 0.234
0.988HisAsn: 0.988 ± 0.469
0.494HisPro: 0.494 ± 0.234
0.0HisGln: 0.0 ± 0.0
0.494HisArg: 0.494 ± 0.234
1.976HisSer: 1.976 ± 0.937
1.976HisThr: 1.976 ± 0.625
1.482HisVal: 1.482 ± 0.736
0.0HisTrp: 0.0 ± 0.0
0.988HisTyr: 0.988 ± 0.896
0.0HisXaa: 0.0 ± 0.0
Ile
1.976IleAla: 1.976 ± 0.937
0.494IleCys: 0.494 ± 0.234
4.941IleAsp: 4.941 ± 1.183
2.47IleGlu: 2.47 ± 1.133
1.482IlePhe: 1.482 ± 0.703
1.976IleGly: 1.976 ± 0.625
0.494IleHis: 0.494 ± 0.234
5.435IleIle: 5.435 ± 0.544
4.447IleLys: 4.447 ± 1.436
4.447IleLeu: 4.447 ± 1.194
0.988IleMet: 0.988 ± 0.469
1.976IleAsn: 1.976 ± 1.791
2.964IlePro: 2.964 ± 1.056
1.976IleGln: 1.976 ± 1.354
2.964IleArg: 2.964 ± 1.056
4.941IleSer: 4.941 ± 2.076
1.976IleThr: 1.976 ± 1.016
2.964IleVal: 2.964 ± 0.647
0.988IleTrp: 0.988 ± 0.469
1.976IleTyr: 1.976 ± 0.937
0.0IleXaa: 0.0 ± 0.0
Lys
4.447LysAla: 4.447 ± 1.194
0.0LysCys: 0.0 ± 0.0
3.458LysAsp: 3.458 ± 0.773
6.423LysGlu: 6.423 ± 2.81
2.964LysPhe: 2.964 ± 1.406
3.953LysGly: 3.953 ± 1.25
0.988LysHis: 0.988 ± 0.469
2.47LysIle: 2.47 ± 0.592
5.435LysLys: 5.435 ± 1.965
5.929LysLeu: 5.929 ± 1.772
0.494LysMet: 0.494 ± 0.234
1.976LysAsn: 1.976 ± 0.937
4.941LysPro: 4.941 ± 1.039
1.976LysGln: 1.976 ± 0.937
3.953LysArg: 3.953 ± 3.582
5.929LysSer: 5.929 ± 0.718
6.423LysThr: 6.423 ± 1.995
6.423LysVal: 6.423 ± 1.812
0.0LysTrp: 0.0 ± 0.0
5.435LysTyr: 5.435 ± 3.089
0.0LysXaa: 0.0 ± 0.0
Leu
3.953LeuAla: 3.953 ± 0.942
2.47LeuCys: 2.47 ± 0.592
6.423LeuAsp: 6.423 ± 1.995
6.917LeuGlu: 6.917 ± 2.219
4.447LeuPhe: 4.447 ± 2.109
2.47LeuGly: 2.47 ± 0.592
0.988LeuHis: 0.988 ± 0.469
3.953LeuIle: 3.953 ± 0.942
5.929LeuLys: 5.929 ± 1.875
8.399LeuLeu: 8.399 ± 3.744
2.964LeuMet: 2.964 ± 1.056
6.423LeuAsn: 6.423 ± 0.919
3.953LeuPro: 3.953 ± 0.544
2.964LeuGln: 2.964 ± 0.647
3.953LeuArg: 3.953 ± 1.25
8.893LeuSer: 8.893 ± 3.656
5.435LeuThr: 5.435 ± 1.553
7.411LeuVal: 7.411 ± 1.775
0.494LeuTrp: 0.494 ± 0.234
0.988LeuTyr: 0.988 ± 1.179
0.0LeuXaa: 0.0 ± 0.0
Met
0.988MetAla: 0.988 ± 0.469
0.988MetCys: 0.988 ± 0.469
0.988MetAsp: 0.988 ± 0.469
0.988MetGlu: 0.988 ± 0.469
0.494MetPhe: 0.494 ± 0.234
0.988MetGly: 0.988 ± 0.469
0.494MetHis: 0.494 ± 0.234
1.976MetIle: 1.976 ± 0.937
1.976MetLys: 1.976 ± 1.354
2.47MetLeu: 2.47 ± 1.009
0.988MetMet: 0.988 ± 0.469
1.482MetAsn: 1.482 ± 1.076
0.988MetPro: 0.988 ± 0.469
1.482MetGln: 1.482 ± 0.703
0.0MetArg: 0.0 ± 0.0
2.47MetSer: 2.47 ± 2.568
1.482MetThr: 1.482 ± 0.703
1.976MetVal: 1.976 ± 0.625
0.494MetTrp: 0.494 ± 0.234
0.494MetTyr: 0.494 ± 0.234
0.0MetXaa: 0.0 ± 0.0
Asn
5.929AsnAla: 5.929 ± 0.718
0.494AsnCys: 0.494 ± 0.234
1.482AsnAsp: 1.482 ± 0.736
2.47AsnGlu: 2.47 ± 1.172
4.447AsnPhe: 4.447 ± 1.134
1.482AsnGly: 1.482 ± 1.076
0.988AsnHis: 0.988 ± 0.469
0.988AsnIle: 0.988 ± 1.179
0.988AsnLys: 0.988 ± 0.469
6.423AsnLeu: 6.423 ± 0.366
0.988AsnMet: 0.988 ± 0.469
1.976AsnAsn: 1.976 ± 0.625
1.482AsnPro: 1.482 ± 1.076
1.482AsnGln: 1.482 ± 2.489
1.482AsnArg: 1.482 ± 2.489
1.976AsnSer: 1.976 ± 1.354
1.482AsnThr: 1.482 ± 0.703
4.941AsnVal: 4.941 ± 2.076
0.494AsnTrp: 0.494 ± 0.234
1.976AsnTyr: 1.976 ± 0.625
0.0AsnXaa: 0.0 ± 0.0
Pro
3.953ProAla: 3.953 ± 1.279
0.494ProCys: 0.494 ± 0.234
3.458ProAsp: 3.458 ± 2.97
3.458ProGlu: 3.458 ± 1.345
2.47ProPhe: 2.47 ± 1.172
1.976ProGly: 1.976 ± 0.937
0.988ProHis: 0.988 ± 0.469
1.482ProIle: 1.482 ± 1.076
4.941ProLys: 4.941 ± 1.183
4.447ProLeu: 4.447 ± 1.271
1.976ProMet: 1.976 ± 1.016
2.964ProAsn: 2.964 ± 0.919
0.494ProPro: 0.494 ± 0.234
0.0ProGln: 0.0 ± 0.0
0.494ProArg: 0.494 ± 0.234
1.976ProSer: 1.976 ± 2.358
0.494ProThr: 0.494 ± 0.234
1.976ProVal: 1.976 ± 0.625
0.988ProTrp: 0.988 ± 1.806
0.494ProTyr: 0.494 ± 0.234
0.0ProXaa: 0.0 ± 0.0
Gln
3.953GlnAla: 3.953 ± 1.279
1.482GlnCys: 1.482 ± 1.076
1.482GlnAsp: 1.482 ± 0.736
0.988GlnGlu: 0.988 ± 0.469
1.976GlnPhe: 1.976 ± 1.354
0.988GlnGly: 0.988 ± 0.469
0.494GlnHis: 0.494 ± 1.083
1.976GlnIle: 1.976 ± 1.016
1.976GlnLys: 1.976 ± 0.937
2.47GlnLeu: 2.47 ± 1.009
0.494GlnMet: 0.494 ± 0.234
0.988GlnAsn: 0.988 ± 0.469
1.482GlnPro: 1.482 ± 0.736
2.964GlnGln: 2.964 ± 1.056
2.964GlnArg: 2.964 ± 2.151
1.482GlnSer: 1.482 ± 1.076
2.964GlnThr: 2.964 ± 1.056
0.988GlnVal: 0.988 ± 0.896
0.0GlnTrp: 0.0 ± 0.0
1.976GlnTyr: 1.976 ± 2.358
0.0GlnXaa: 0.0 ± 0.0
Arg
2.964ArgAla: 2.964 ± 1.97
0.494ArgCys: 0.494 ± 0.234
5.435ArgAsp: 5.435 ± 0.544
1.976ArgGlu: 1.976 ± 0.625
1.482ArgPhe: 1.482 ± 1.579
2.47ArgGly: 2.47 ± 1.172
0.988ArgHis: 0.988 ± 0.469
1.976ArgIle: 1.976 ± 1.354
3.953ArgLys: 3.953 ± 2.355
3.458ArgLeu: 3.458 ± 1.345
0.988ArgMet: 0.988 ± 0.469
1.482ArgAsn: 1.482 ± 1.076
1.976ArgPro: 1.976 ± 1.354
0.988ArgGln: 0.988 ± 1.179
3.458ArgArg: 3.458 ± 1.641
3.458ArgSer: 3.458 ± 0.718
2.47ArgThr: 2.47 ± 1.172
5.435ArgVal: 5.435 ± 2.053
0.988ArgTrp: 0.988 ± 0.469
0.988ArgTyr: 0.988 ± 0.896
0.0ArgXaa: 0.0 ± 0.0
Ser
5.435SerAla: 5.435 ± 4.391
1.482SerCys: 1.482 ± 0.703
2.47SerAsp: 2.47 ± 0.592
5.435SerGlu: 5.435 ± 1.598
4.941SerPhe: 4.941 ± 0.431
2.964SerGly: 2.964 ± 0.647
0.494SerHis: 0.494 ± 0.234
3.953SerIle: 3.953 ± 1.25
6.423SerLys: 6.423 ± 2.81
6.423SerLeu: 6.423 ± 3.047
0.494SerMet: 0.494 ± 0.234
3.458SerAsn: 3.458 ± 2.08
0.988SerPro: 0.988 ± 0.469
4.447SerGln: 4.447 ± 3.227
3.953SerArg: 3.953 ± 2.033
2.47SerSer: 2.47 ± 1.172
3.953SerThr: 3.953 ± 1.25
5.435SerVal: 5.435 ± 4.304
0.0SerTrp: 0.0 ± 0.0
2.47SerTyr: 2.47 ± 2.568
0.0SerXaa: 0.0 ± 0.0
Thr
4.447ThrAla: 4.447 ± 1.436
1.482ThrCys: 1.482 ± 0.703
0.988ThrAsp: 0.988 ± 0.469
1.482ThrGlu: 1.482 ± 1.076
3.458ThrPhe: 3.458 ± 1.641
2.964ThrGly: 2.964 ± 0.919
0.988ThrHis: 0.988 ± 0.469
3.458ThrIle: 3.458 ± 0.773
1.976ThrLys: 1.976 ± 0.625
6.917ThrLeu: 6.917 ± 2.219
1.482ThrMet: 1.482 ± 0.767
2.964ThrAsn: 2.964 ± 1.97
1.976ThrPro: 1.976 ± 1.016
2.47ThrGln: 2.47 ± 2.245
3.953ThrArg: 3.953 ± 0.544
1.976ThrSer: 1.976 ± 0.937
3.458ThrThr: 3.458 ± 1.149
5.435ThrVal: 5.435 ± 2.05
0.988ThrTrp: 0.988 ± 0.469
3.458ThrTyr: 3.458 ± 0.773
0.0ThrXaa: 0.0 ± 0.0
Val
8.399ValAla: 8.399 ± 1.627
0.988ValCys: 0.988 ± 0.469
7.905ValAsp: 7.905 ± 2.336
4.941ValGlu: 4.941 ± 1.183
1.482ValPhe: 1.482 ± 0.736
1.976ValGly: 1.976 ± 1.791
4.447ValHis: 4.447 ± 1.134
5.929ValIle: 5.929 ± 0.583
4.941ValLys: 4.941 ± 1.183
5.435ValLeu: 5.435 ± 1.218
1.482ValMet: 1.482 ± 0.79
4.941ValAsn: 4.941 ± 0.431
5.435ValPro: 5.435 ± 3.089
2.964ValGln: 2.964 ± 1.406
4.941ValArg: 4.941 ± 0.431
4.447ValSer: 4.447 ± 5.92
4.941ValThr: 4.941 ± 1.039
5.929ValVal: 5.929 ± 4.432
1.482ValTrp: 1.482 ± 1.076
4.447ValTyr: 4.447 ± 1.436
0.0ValXaa: 0.0 ± 0.0
Trp
0.494TrpAla: 0.494 ± 1.317
0.0TrpCys: 0.0 ± 0.0
1.976TrpAsp: 1.976 ± 0.937
0.494TrpGlu: 0.494 ± 0.234
0.988TrpPhe: 0.988 ± 0.469
0.494TrpGly: 0.494 ± 0.234
0.494TrpHis: 0.494 ± 0.234
0.0TrpIle: 0.0 ± 0.0
0.494TrpLys: 0.494 ± 0.234
1.976TrpLeu: 1.976 ± 0.625
0.0TrpMet: 0.0 ± 0.0
0.494TrpAsn: 0.494 ± 0.234
0.0TrpPro: 0.0 ± 0.0
0.988TrpGln: 0.988 ± 2.166
0.494TrpArg: 0.494 ± 0.234
0.0TrpSer: 0.0 ± 0.0
0.988TrpThr: 0.988 ± 1.179
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.988TrpTyr: 0.988 ± 0.469
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.976TyrAla: 1.976 ± 0.625
0.988TyrCys: 0.988 ± 0.469
3.458TyrAsp: 3.458 ± 1.641
1.482TyrGlu: 1.482 ± 1.579
2.47TyrPhe: 2.47 ± 1.133
1.976TyrGly: 1.976 ± 0.937
1.482TyrHis: 1.482 ± 0.703
0.988TyrIle: 0.988 ± 0.469
3.953TyrLys: 3.953 ± 1.25
1.482TyrLeu: 1.482 ± 0.703
0.494TyrMet: 0.494 ± 1.317
0.988TyrAsn: 0.988 ± 1.179
1.482TyrPro: 1.482 ± 0.703
2.964TyrGln: 2.964 ± 2.151
1.976TyrArg: 1.976 ± 3.055
0.988TyrSer: 0.988 ± 0.469
2.964TyrThr: 2.964 ± 1.406
3.953TyrVal: 3.953 ± 0.544
0.0TyrTrp: 0.0 ± 0.0
1.976TyrTyr: 1.976 ± 0.937
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (2025 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski