Amino acid dipepetide frequency for Tomato yellow leaf curl Sardinia virus (isolate Spain-1) (TYLCSV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.566AlaAla: 4.566 ± 1.553
0.913AlaCys: 0.913 ± 0.686
0.913AlaAsp: 0.913 ± 1.211
0.913AlaGlu: 0.913 ± 1.211
0.0AlaPhe: 0.0 ± 0.0
0.913AlaGly: 0.913 ± 0.651
2.74AlaHis: 2.74 ± 1.348
3.653AlaIle: 3.653 ± 1.928
5.479AlaLys: 5.479 ± 1.568
3.653AlaLeu: 3.653 ± 1.214
0.913AlaMet: 0.913 ± 0.602
1.826AlaAsn: 1.826 ± 1.17
3.653AlaPro: 3.653 ± 1.334
0.913AlaGln: 0.913 ± 0.651
4.566AlaArg: 4.566 ± 2.56
2.74AlaSer: 2.74 ± 1.538
3.653AlaThr: 3.653 ± 2.069
1.826AlaVal: 1.826 ± 1.165
0.913AlaTrp: 0.913 ± 0.651
0.913AlaTyr: 0.913 ± 0.651
0.0AlaXaa: 0.0 ± 0.0
Cys
0.913CysAla: 0.913 ± 1.06
1.826CysCys: 1.826 ± 2.422
0.0CysAsp: 0.0 ± 0.0
0.913CysGlu: 0.913 ± 0.686
0.913CysPhe: 0.913 ± 1.143
1.826CysGly: 1.826 ± 1.01
0.0CysHis: 0.0 ± 0.0
1.826CysIle: 1.826 ± 1.167
1.826CysLys: 1.826 ± 0.8
0.913CysLeu: 0.913 ± 0.686
0.913CysMet: 0.913 ± 1.211
0.913CysAsn: 0.913 ± 0.651
1.826CysPro: 1.826 ± 2.422
0.0CysGln: 0.0 ± 0.0
0.913CysArg: 0.913 ± 0.651
3.653CysSer: 3.653 ± 2.109
0.913CysThr: 0.913 ± 0.686
0.913CysVal: 0.913 ± 0.686
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.74AspAla: 2.74 ± 1.287
1.826AspCys: 1.826 ± 2.121
3.653AspAsp: 3.653 ± 1.178
2.74AspGlu: 2.74 ± 1.287
0.913AspPhe: 0.913 ± 0.686
2.74AspGly: 2.74 ± 1.952
0.0AspHis: 0.0 ± 0.0
0.913AspIle: 0.913 ± 0.686
0.913AspLys: 0.913 ± 0.651
9.132AspLeu: 9.132 ± 3.154
0.0AspMet: 0.0 ± 0.0
2.74AspAsn: 2.74 ± 2.122
2.74AspPro: 2.74 ± 1.456
1.826AspGln: 1.826 ± 1.111
2.74AspArg: 2.74 ± 1.341
5.479AspSer: 5.479 ± 2.106
0.0AspThr: 0.0 ± 0.0
9.132AspVal: 9.132 ± 2.065
1.826AspTrp: 1.826 ± 1.01
2.74AspTyr: 2.74 ± 1.348
0.0AspXaa: 0.0 ± 0.0
Glu
3.653GluAla: 3.653 ± 1.928
0.0GluCys: 0.0 ± 0.0
1.826GluAsp: 1.826 ± 1.111
4.566GluGlu: 4.566 ± 1.756
1.826GluPhe: 1.826 ± 1.17
4.566GluGly: 4.566 ± 1.206
0.913GluHis: 0.913 ± 0.651
1.826GluIle: 1.826 ± 2.286
0.913GluLys: 0.913 ± 0.651
4.566GluLeu: 4.566 ± 1.917
0.913GluMet: 0.913 ± 1.09
4.566GluAsn: 4.566 ± 1.846
1.826GluPro: 1.826 ± 1.284
4.566GluGln: 4.566 ± 1.846
0.0GluArg: 0.0 ± 0.0
0.0GluSer: 0.0 ± 0.0
1.826GluThr: 1.826 ± 1.17
0.913GluVal: 0.913 ± 1.09
1.826GluTrp: 1.826 ± 1.01
1.826GluTyr: 1.826 ± 1.093
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.913PheCys: 0.913 ± 0.686
4.566PheAsp: 4.566 ± 1.398
2.74PheGlu: 2.74 ± 2.14
3.653PhePhe: 3.653 ± 1.389
1.826PheGly: 1.826 ± 1.372
3.653PheHis: 3.653 ± 1.222
0.0PheIle: 0.0 ± 0.0
3.653PheLys: 3.653 ± 1.222
7.306PheLeu: 7.306 ± 3.045
0.913PheMet: 0.913 ± 0.651
4.566PheAsn: 4.566 ± 1.992
2.74PhePro: 2.74 ± 1.338
3.653PheGln: 3.653 ± 1.875
2.74PheArg: 2.74 ± 2.575
1.826PheSer: 1.826 ± 1.482
2.74PheThr: 2.74 ± 1.273
0.913PheVal: 0.913 ± 0.651
0.0PheTrp: 0.0 ± 0.0
0.913PheTyr: 0.913 ± 0.686
0.0PheXaa: 0.0 ± 0.0
Gly
0.913GlyAla: 0.913 ± 0.651
1.826GlyCys: 1.826 ± 1.167
3.653GlyAsp: 3.653 ± 1.222
1.826GlyGlu: 1.826 ± 1.613
0.913GlyPhe: 0.913 ± 1.06
2.74GlyGly: 2.74 ± 1.287
2.74GlyHis: 2.74 ± 1.348
3.653GlyIle: 3.653 ± 1.315
4.566GlyLys: 4.566 ± 2.042
0.913GlyLeu: 0.913 ± 1.211
0.913GlyMet: 0.913 ± 0.686
0.913GlyAsn: 0.913 ± 1.09
3.653GlyPro: 3.653 ± 1.6
2.74GlyGln: 2.74 ± 1.287
0.913GlyArg: 0.913 ± 0.651
3.653GlySer: 3.653 ± 1.339
2.74GlyThr: 2.74 ± 1.002
4.566GlyVal: 4.566 ± 2.526
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.826HisAla: 1.826 ± 1.372
2.74HisCys: 2.74 ± 2.37
1.826HisAsp: 1.826 ± 1.554
1.826HisGlu: 1.826 ± 1.093
3.653HisPhe: 3.653 ± 1.875
1.826HisGly: 1.826 ± 1.554
1.826HisHis: 1.826 ± 2.121
1.826HisIle: 1.826 ± 1.482
0.913HisLys: 0.913 ± 1.143
3.653HisLeu: 3.653 ± 2.02
0.913HisMet: 0.913 ± 0.651
3.653HisAsn: 3.653 ± 2.187
0.913HisPro: 0.913 ± 0.651
3.653HisGln: 3.653 ± 1.152
2.74HisArg: 2.74 ± 1.002
0.0HisSer: 0.0 ± 0.0
2.74HisThr: 2.74 ± 2.059
1.826HisVal: 1.826 ± 1.284
0.913HisTrp: 0.913 ± 0.651
1.826HisTyr: 1.826 ± 1.302
0.0HisXaa: 0.0 ± 0.0
Ile
0.913IleAla: 0.913 ± 1.06
0.913IleCys: 0.913 ± 0.651
3.653IleAsp: 3.653 ± 1.875
1.826IleGlu: 1.826 ± 1.093
2.74IlePhe: 2.74 ± 1.328
0.913IleGly: 0.913 ± 1.143
2.74IleHis: 2.74 ± 1.273
0.0IleIle: 0.0 ± 0.0
9.132IleLys: 9.132 ± 1.427
2.74IleLeu: 2.74 ± 1.341
0.913IleMet: 0.913 ± 1.211
3.653IleAsn: 3.653 ± 1.831
1.826IlePro: 1.826 ± 1.01
5.479IleGln: 5.479 ± 3.03
5.479IleArg: 5.479 ± 3.123
5.479IleSer: 5.479 ± 2.584
4.566IleThr: 4.566 ± 3.488
0.913IleVal: 0.913 ± 0.651
2.74IleTrp: 2.74 ± 1.53
1.826IleTyr: 1.826 ± 1.372
0.0IleXaa: 0.0 ± 0.0
Lys
2.74LysAla: 2.74 ± 1.348
1.826LysCys: 1.826 ± 1.093
0.913LysAsp: 0.913 ± 0.651
4.566LysGlu: 4.566 ± 2.496
1.826LysPhe: 1.826 ± 0.8
0.913LysGly: 0.913 ± 0.651
2.74LysHis: 2.74 ± 1.287
4.566LysIle: 4.566 ± 1.415
2.74LysLys: 2.74 ± 1.002
0.913LysLeu: 0.913 ± 0.686
0.0LysMet: 0.0 ± 0.0
4.566LysAsn: 4.566 ± 2.496
2.74LysPro: 2.74 ± 1.139
0.913LysGln: 0.913 ± 0.686
5.479LysArg: 5.479 ± 2.57
5.479LysSer: 5.479 ± 2.094
1.826LysThr: 1.826 ± 1.17
3.653LysVal: 3.653 ± 1.974
0.0LysTrp: 0.0 ± 0.0
6.393LysTyr: 6.393 ± 2.849
0.0LysXaa: 0.0 ± 0.0
Leu
1.826LeuAla: 1.826 ± 1.17
1.826LeuCys: 1.826 ± 1.302
6.393LeuAsp: 6.393 ± 3.25
4.566LeuGlu: 4.566 ± 1.756
1.826LeuPhe: 1.826 ± 1.093
3.653LeuGly: 3.653 ± 1.152
2.74LeuHis: 2.74 ± 1.952
4.566LeuIle: 4.566 ± 2.278
3.653LeuLys: 3.653 ± 1.6
5.479LeuLeu: 5.479 ± 1.939
1.826LeuMet: 1.826 ± 1.368
6.393LeuAsn: 6.393 ± 3.97
0.913LeuPro: 0.913 ± 1.06
5.479LeuGln: 5.479 ± 2.327
6.393LeuArg: 6.393 ± 3.788
4.566LeuSer: 4.566 ± 2.541
3.653LeuThr: 3.653 ± 2.646
2.74LeuVal: 2.74 ± 1.139
0.0LeuTrp: 0.0 ± 0.0
3.653LeuTyr: 3.653 ± 2.325
0.0LeuXaa: 0.0 ± 0.0
Met
1.826MetAla: 1.826 ± 0.8
0.0MetCys: 0.0 ± 0.0
4.566MetAsp: 4.566 ± 1.333
0.0MetGlu: 0.0 ± 0.0
3.653MetPhe: 3.653 ± 1.73
1.826MetGly: 1.826 ± 1.111
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.913MetLys: 0.913 ± 0.686
1.826MetLeu: 1.826 ± 1.17
0.913MetMet: 0.913 ± 1.044
0.0MetAsn: 0.0 ± 0.0
0.913MetPro: 0.913 ± 0.686
0.913MetGln: 0.913 ± 1.06
0.913MetArg: 0.913 ± 0.686
0.0MetSer: 0.0 ± 0.0
0.913MetThr: 0.913 ± 1.09
0.0MetVal: 0.0 ± 0.0
1.826MetTrp: 1.826 ± 1.17
2.74MetTyr: 2.74 ± 2.059
0.0MetXaa: 0.0 ± 0.0
Asn
5.479AsnAla: 5.479 ± 2.308
0.913AsnCys: 0.913 ± 0.651
1.826AsnAsp: 1.826 ± 0.8
2.74AsnGlu: 2.74 ± 1.538
3.653AsnPhe: 3.653 ± 2.321
0.913AsnGly: 0.913 ± 1.09
4.566AsnHis: 4.566 ± 2.13
4.566AsnIle: 4.566 ± 1.067
1.826AsnLys: 1.826 ± 1.01
3.653AsnLeu: 3.653 ± 2.368
1.826AsnMet: 1.826 ± 1.264
3.653AsnAsn: 3.653 ± 2.187
2.74AsnPro: 2.74 ± 0.996
6.393AsnGln: 6.393 ± 1.747
1.826AsnArg: 1.826 ± 1.17
2.74AsnSer: 2.74 ± 1.454
4.566AsnThr: 4.566 ± 1.135
3.653AsnVal: 3.653 ± 1.426
0.913AsnTrp: 0.913 ± 0.651
0.913AsnTyr: 0.913 ± 0.651
0.0AsnXaa: 0.0 ± 0.0
Pro
0.913ProAla: 0.913 ± 0.651
1.826ProCys: 1.826 ± 1.284
3.653ProAsp: 3.653 ± 1.304
0.0ProGlu: 0.0 ± 0.0
2.74ProPhe: 2.74 ± 0.996
0.913ProGly: 0.913 ± 0.651
5.479ProHis: 5.479 ± 2.236
2.74ProIle: 2.74 ± 1.966
2.74ProLys: 2.74 ± 1.287
2.74ProLeu: 2.74 ± 1.348
2.74ProMet: 2.74 ± 1.707
2.74ProAsn: 2.74 ± 1.338
0.913ProPro: 0.913 ± 0.651
2.74ProGln: 2.74 ± 1.31
3.653ProArg: 3.653 ± 1.304
2.74ProSer: 2.74 ± 1.594
8.219ProThr: 8.219 ± 2.164
3.653ProVal: 3.653 ± 1.473
0.913ProTrp: 0.913 ± 0.651
2.74ProTyr: 2.74 ± 1.341
0.0ProXaa: 0.0 ± 0.0
Gln
4.566GlnAla: 4.566 ± 2.606
0.913GlnCys: 0.913 ± 0.686
0.913GlnAsp: 0.913 ± 0.651
2.74GlnGlu: 2.74 ± 1.068
1.826GlnPhe: 1.826 ± 1.01
2.74GlnGly: 2.74 ± 1.068
2.74GlnHis: 2.74 ± 1.855
5.479GlnIle: 5.479 ± 2.122
1.826GlnLys: 1.826 ± 1.17
5.479GlnLeu: 5.479 ± 2.064
0.913GlnMet: 0.913 ± 1.06
1.826GlnAsn: 1.826 ± 1.284
9.132GlnPro: 9.132 ± 2.784
3.653GlnGln: 3.653 ± 2.073
1.826GlnArg: 1.826 ± 0.8
4.566GlnSer: 4.566 ± 1.067
3.653GlnThr: 3.653 ± 1.831
7.306GlnVal: 7.306 ± 2.007
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.74ArgAla: 2.74 ± 1.487
1.826ArgCys: 1.826 ± 1.284
7.306ArgAsp: 7.306 ± 2.342
1.826ArgGlu: 1.826 ± 1.111
4.566ArgPhe: 4.566 ± 1.398
2.74ArgGly: 2.74 ± 1.002
1.826ArgHis: 1.826 ± 1.565
1.826ArgIle: 1.826 ± 1.165
3.653ArgLys: 3.653 ± 2.069
2.74ArgLeu: 2.74 ± 1.841
1.826ArgMet: 1.826 ± 1.372
0.0ArgAsn: 0.0 ± 0.0
3.653ArgPro: 3.653 ± 1.6
4.566ArgGln: 4.566 ± 2.316
7.306ArgArg: 7.306 ± 3.486
5.479ArgSer: 5.479 ± 1.898
4.566ArgThr: 4.566 ± 2.141
4.566ArgVal: 4.566 ± 1.294
0.0ArgTrp: 0.0 ± 0.0
2.74ArgTyr: 2.74 ± 1.487
0.0ArgXaa: 0.0 ± 0.0
Ser
1.826SerAla: 1.826 ± 1.302
0.0SerCys: 0.0 ± 0.0
2.74SerAsp: 2.74 ± 1.002
2.74SerGlu: 2.74 ± 1.952
4.566SerPhe: 4.566 ± 1.815
2.74SerGly: 2.74 ± 1.532
0.913SerHis: 0.913 ± 1.06
4.566SerIle: 4.566 ± 2.116
5.479SerLys: 5.479 ± 2.009
3.653SerLeu: 3.653 ± 1.353
0.0SerMet: 0.0 ± 0.0
5.479SerAsn: 5.479 ± 2.094
8.219SerPro: 8.219 ± 1.845
4.566SerGln: 4.566 ± 2.941
5.479SerArg: 5.479 ± 4.112
10.959SerSer: 10.959 ± 3.852
6.393SerThr: 6.393 ± 4.314
1.826SerVal: 1.826 ± 2.422
0.913SerTrp: 0.913 ± 0.686
2.74SerTyr: 2.74 ± 1.002
0.0SerXaa: 0.0 ± 0.0
Thr
3.653ThrAla: 3.653 ± 1.264
0.913ThrCys: 0.913 ± 1.09
1.826ThrAsp: 1.826 ± 2.181
2.74ThrGlu: 2.74 ± 1.558
3.653ThrPhe: 3.653 ± 2.368
5.479ThrGly: 5.479 ± 2.015
3.653ThrHis: 3.653 ± 2.159
4.566ThrIle: 4.566 ± 2.123
0.913ThrLys: 0.913 ± 0.651
4.566ThrLeu: 4.566 ± 1.355
0.913ThrMet: 0.913 ± 0.651
6.393ThrAsn: 6.393 ± 1.427
3.653ThrPro: 3.653 ± 1.334
1.826ThrGln: 1.826 ± 1.482
3.653ThrArg: 3.653 ± 1.264
6.393ThrSer: 6.393 ± 2.104
1.826ThrThr: 1.826 ± 1.503
3.653ThrVal: 3.653 ± 2.159
0.0ThrTrp: 0.0 ± 0.0
1.826ThrTyr: 1.826 ± 1.284
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
0.0ValCys: 0.0 ± 0.0
2.74ValAsp: 2.74 ± 1.273
0.913ValGlu: 0.913 ± 1.211
3.653ValPhe: 3.653 ± 1.989
1.826ValGly: 1.826 ± 1.372
1.826ValHis: 1.826 ± 1.554
6.393ValIle: 6.393 ± 3.114
2.74ValLys: 2.74 ± 1.341
2.74ValLeu: 2.74 ± 1.454
2.74ValMet: 2.74 ± 1.341
1.826ValAsn: 1.826 ± 1.161
2.74ValPro: 2.74 ± 1.287
4.566ValGln: 4.566 ± 2.628
3.653ValArg: 3.653 ± 2.159
8.219ValSer: 8.219 ± 1.628
2.74ValThr: 2.74 ± 1.341
2.74ValVal: 2.74 ± 2.059
0.0ValTrp: 0.0 ± 0.0
5.479ValTyr: 5.479 ± 1.999
0.0ValXaa: 0.0 ± 0.0
Trp
1.826TrpAla: 1.826 ± 1.302
0.0TrpCys: 0.0 ± 0.0
0.913TrpAsp: 0.913 ± 1.211
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.913TrpGly: 0.913 ± 0.651
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.913TrpMet: 0.913 ± 0.686
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.913TrpGln: 0.913 ± 0.651
1.826TrpArg: 1.826 ± 1.01
0.913TrpSer: 0.913 ± 1.06
1.826TrpThr: 1.826 ± 1.165
0.913TrpVal: 0.913 ± 0.651
0.0TrpTrp: 0.0 ± 0.0
1.826TrpTyr: 1.826 ± 1.111
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.74TyrAla: 2.74 ± 1.139
0.0TyrCys: 0.0 ± 0.0
0.913TyrAsp: 0.913 ± 0.686
2.74TyrGlu: 2.74 ± 1.666
2.74TyrPhe: 2.74 ± 0.996
1.826TyrGly: 1.826 ± 0.8
0.0TyrHis: 0.0 ± 0.0
5.479TyrIle: 5.479 ± 1.392
0.913TyrLys: 0.913 ± 1.143
5.479TyrLeu: 5.479 ± 1.514
1.826TyrMet: 1.826 ± 1.037
3.653TyrAsn: 3.653 ± 1.989
0.913TyrPro: 0.913 ± 1.09
2.74TyrGln: 2.74 ± 1.487
3.653TyrArg: 3.653 ± 2.745
0.913TyrSer: 0.913 ± 0.651
2.74TyrThr: 2.74 ± 1.487
1.826TyrVal: 1.826 ± 1.093
0.0TyrTrp: 0.0 ± 0.0
0.913TyrTyr: 0.913 ± 1.06
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1096 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski