Amino acid dipepetide frequency for Phytophthora palmivora var. palmivora

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.584AlaAla: 8.584 ± 0.045	1.172AlaCys: 1.172 ± 0.012	4.449AlaAsp: 4.449 ± 0.028	5.428AlaGlu: 5.428 ± 0.037	3.125AlaPhe: 3.125 ± 0.021	4.54AlaGly: 4.54 ± 0.029	1.746AlaHis: 1.746 ± 0.014	3.797AlaIle: 3.797 ± 0.022	4.697AlaLys: 4.697 ± 0.028	7.988AlaLeu: 7.988 ± 0.038	2.304AlaMet: 2.304 ± 0.019	2.969AlaAsn: 2.969 ± 0.019	3.941AlaPro: 3.941 ± 0.029	3.375AlaGln: 3.375 ± 0.021	4.712AlaArg: 4.712 ± 0.028	6.759AlaSer: 6.759 ± 0.033	5.378AlaThr: 5.378 ± 0.027	5.884AlaVal: 5.884 ± 0.036	0.857AlaTrp: 0.857 ± 0.01	2.034AlaTyr: 2.034 ± 0.016	0.002AlaXaa: 0.002 ± 0.0
Cys	1.165CysAla: 1.165 ± 0.013	0.35CysCys: 0.35 ± 0.007	0.874CysAsp: 0.874 ± 0.011	0.936CysGlu: 0.936 ± 0.01	0.66CysPhe: 0.66 ± 0.01	1.198CysGly: 1.198 ± 0.014	0.42CysHis: 0.42 ± 0.007	0.796CysIle: 0.796 ± 0.01	0.774CysLys: 0.774 ± 0.012	1.294CysLeu: 1.294 ± 0.013	0.408CysMet: 0.408 ± 0.008	0.538CysAsn: 0.538 ± 0.009	0.744CysPro: 0.744 ± 0.01	0.576CysGln: 0.576 ± 0.009	0.91CysArg: 0.91 ± 0.011	1.242CysSer: 1.242 ± 0.015	0.912CysThr: 0.912 ± 0.011	1.249CysVal: 1.249 ± 0.016	0.247CysTrp: 0.247 ± 0.006	0.467CysTyr: 0.467 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.159AspAla: 5.159 ± 0.027	0.785AspCys: 0.785 ± 0.01	4.479AspAsp: 4.479 ± 0.033	5.052AspGlu: 5.052 ± 0.031	2.239AspPhe: 2.239 ± 0.015	3.86AspGly: 3.86 ± 0.024	1.266AspHis: 1.266 ± 0.012	2.805AspIle: 2.805 ± 0.023	2.724AspLys: 2.724 ± 0.019	5.222AspLeu: 5.222 ± 0.029	1.404AspMet: 1.404 ± 0.014	2.052AspAsn: 2.052 ± 0.018	2.681AspPro: 2.681 ± 0.022	2.055AspGln: 2.055 ± 0.016	3.12AspArg: 3.12 ± 0.024	4.151AspSer: 4.151 ± 0.029	2.918AspThr: 2.918 ± 0.019	4.438AspVal: 4.438 ± 0.025	0.735AspTrp: 0.735 ± 0.01	1.603AspTyr: 1.603 ± 0.014	0.001AspXaa: 0.001 ± 0.0
Glu	5.612GluAla: 5.612 ± 0.03	0.901GluCys: 0.901 ± 0.011	4.481GluAsp: 4.481 ± 0.031	5.751GluGlu: 5.751 ± 0.047	2.283GluPhe: 2.283 ± 0.016	3.36GluGly: 3.36 ± 0.023	1.525GluHis: 1.525 ± 0.014	3.145GluIle: 3.145 ± 0.02	3.823GluLys: 3.823 ± 0.026	6.389GluLeu: 6.389 ± 0.037	1.801GluMet: 1.801 ± 0.018	2.565GluAsn: 2.565 ± 0.019	2.275GluPro: 2.275 ± 0.02	2.816GluGln: 2.816 ± 0.02	4.265GluArg: 4.265 ± 0.033	4.348GluSer: 4.348 ± 0.029	3.64GluThr: 3.64 ± 0.028	4.451GluVal: 4.451 ± 0.027	0.857GluTrp: 0.857 ± 0.012	1.941GluTyr: 1.941 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	3.082PheAla: 3.082 ± 0.021	0.727PheCys: 0.727 ± 0.01	2.337PheAsp: 2.337 ± 0.018	2.212PheGlu: 2.212 ± 0.015	1.499PhePhe: 1.499 ± 0.015	2.574PheGly: 2.574 ± 0.02	0.894PheHis: 0.894 ± 0.01	1.609PheIle: 1.609 ± 0.014	1.613PheLys: 1.613 ± 0.013	3.464PheLeu: 3.464 ± 0.024	0.978PheMet: 0.978 ± 0.012	1.335PheAsn: 1.335 ± 0.014	1.605PhePro: 1.605 ± 0.015	1.472PheGln: 1.472 ± 0.014	2.193PheArg: 2.193 ± 0.017	2.646PheSer: 2.646 ± 0.02	2.191PheThr: 2.191 ± 0.016	2.911PheVal: 2.911 ± 0.02	0.554PheTrp: 0.554 ± 0.008	1.186PheTyr: 1.186 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	4.575GlyAla: 4.575 ± 0.03	1.075GlyCys: 1.075 ± 0.014	3.631GlyAsp: 3.631 ± 0.023	3.422GlyGlu: 3.422 ± 0.021	2.339GlyPhe: 2.339 ± 0.02	4.37GlyGly: 4.37 ± 0.035	1.482GlyHis: 1.482 ± 0.016	2.858GlyIle: 2.858 ± 0.019	3.357GlyLys: 3.357 ± 0.021	5.043GlyLeu: 5.043 ± 0.028	1.553GlyMet: 1.553 ± 0.017	2.507GlyAsn: 2.507 ± 0.019	2.131GlyPro: 2.131 ± 0.018	1.953GlyGln: 1.953 ± 0.017	3.45GlyArg: 3.45 ± 0.023	5.126GlySer: 5.126 ± 0.035	3.451GlyThr: 3.451 ± 0.027	4.389GlyVal: 4.389 ± 0.027	0.79GlyTrp: 0.79 ± 0.011	1.978GlyTyr: 1.978 ± 0.018	0.002GlyXaa: 0.002 ± 0.0
His	1.897HisAla: 1.897 ± 0.017	0.42HisCys: 0.42 ± 0.008	1.321HisAsp: 1.321 ± 0.014	1.567HisGlu: 1.567 ± 0.016	1.046HisPhe: 1.046 ± 0.011	1.653HisGly: 1.653 ± 0.017	0.709HisHis: 0.709 ± 0.011	1.083HisIle: 1.083 ± 0.012	1.131HisLys: 1.131 ± 0.012	2.343HisLeu: 2.343 ± 0.018	0.548HisMet: 0.548 ± 0.008	0.787HisAsn: 0.787 ± 0.011	1.286HisPro: 1.286 ± 0.014	1.004HisGln: 1.004 ± 0.012	1.599HisArg: 1.599 ± 0.014	1.674HisSer: 1.674 ± 0.015	1.181HisThr: 1.181 ± 0.013	1.828HisVal: 1.828 ± 0.016	0.371HisTrp: 0.371 ± 0.006	0.737HisTyr: 0.737 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	3.893IleAla: 3.893 ± 0.022	0.794IleCys: 0.794 ± 0.011	2.85IleAsp: 2.85 ± 0.019	2.807IleGlu: 2.807 ± 0.019	1.684IlePhe: 1.684 ± 0.017	2.597IleGly: 2.597 ± 0.019	0.991IleHis: 0.991 ± 0.011	1.821IleIle: 1.821 ± 0.018	2.278IleLys: 2.278 ± 0.019	3.873IleLeu: 3.873 ± 0.024	1.034IleMet: 1.034 ± 0.012	1.577IleAsn: 1.577 ± 0.014	2.36IlePro: 2.36 ± 0.017	1.886IleGln: 1.886 ± 0.017	2.616IleArg: 2.616 ± 0.018	3.343IleSer: 3.343 ± 0.019	2.545IleThr: 2.545 ± 0.018	3.309IleVal: 3.309 ± 0.02	0.555IleTrp: 0.555 ± 0.009	1.247IleTyr: 1.247 ± 0.013	0.0IleXaa: 0.0 ± 0.0
Lys	4.38LysAla: 4.38 ± 0.026	0.818LysCys: 0.818 ± 0.011	2.84LysAsp: 2.84 ± 0.021	3.534LysGlu: 3.534 ± 0.026	1.808LysPhe: 1.808 ± 0.016	2.554LysGly: 2.554 ± 0.021	1.409LysHis: 1.409 ± 0.015	2.374LysIle: 2.374 ± 0.022	4.145LysLys: 4.145 ± 0.035	5.259LysLeu: 5.259 ± 0.028	1.462LysMet: 1.462 ± 0.013	2.099LysAsn: 2.099 ± 0.016	2.523LysPro: 2.523 ± 0.019	2.452LysGln: 2.452 ± 0.018	4.039LysArg: 4.039 ± 0.023	3.789LysSer: 3.789 ± 0.027	3.377LysThr: 3.377 ± 0.022	3.368LysVal: 3.368 ± 0.021	0.818LysTrp: 0.818 ± 0.01	1.7LysTyr: 1.7 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	7.693LeuAla: 7.693 ± 0.037	1.484LeuCys: 1.484 ± 0.015	5.182LeuAsp: 5.182 ± 0.029	6.078LeuGlu: 6.078 ± 0.037	3.351LeuPhe: 3.351 ± 0.027	5.127LeuGly: 5.127 ± 0.029	2.52LeuHis: 2.52 ± 0.019	3.44LeuIle: 3.44 ± 0.024	5.221LeuLys: 5.221 ± 0.029	9.312LeuLeu: 9.312 ± 0.05	2.21LeuMet: 2.21 ± 0.015	3.335LeuAsn: 3.335 ± 0.022	4.65LeuPro: 4.65 ± 0.026	4.522LeuGln: 4.522 ± 0.03	6.398LeuArg: 6.398 ± 0.03	6.907LeuSer: 6.907 ± 0.03	4.992LeuThr: 4.992 ± 0.025	6.42LeuVal: 6.42 ± 0.037	1.084LeuTrp: 1.084 ± 0.012	2.343LeuTyr: 2.343 ± 0.016	0.001LeuXaa: 0.001 ± 0.0
Met	2.159MetAla: 2.159 ± 0.017	0.364MetCys: 0.364 ± 0.007	1.638MetAsp: 1.638 ± 0.014	1.856MetGlu: 1.856 ± 0.016	0.814MetPhe: 0.814 ± 0.01	1.373MetGly: 1.373 ± 0.013	0.591MetHis: 0.591 ± 0.009	1.06MetIle: 1.06 ± 0.011	1.566MetLys: 1.566 ± 0.014	2.368MetLeu: 2.368 ± 0.018	0.713MetMet: 0.713 ± 0.01	0.939MetAsn: 0.939 ± 0.011	1.123MetPro: 1.123 ± 0.012	1.097MetGln: 1.097 ± 0.013	1.593MetArg: 1.593 ± 0.013	1.885MetSer: 1.885 ± 0.015	1.594MetThr: 1.594 ± 0.016	1.758MetVal: 1.758 ± 0.016	0.338MetTrp: 0.338 ± 0.006	0.657MetTyr: 0.657 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.317AsnAla: 3.317 ± 0.02	0.597AsnCys: 0.597 ± 0.009	2.11AsnAsp: 2.11 ± 0.019	2.333AsnGlu: 2.333 ± 0.017	1.313AsnPhe: 1.313 ± 0.012	2.718AsnGly: 2.718 ± 0.021	0.847AsnHis: 0.847 ± 0.01	1.697AsnIle: 1.697 ± 0.016	1.864AsnLys: 1.864 ± 0.015	3.128AsnLeu: 3.128 ± 0.021	0.92AsnMet: 0.92 ± 0.012	1.551AsnAsn: 1.551 ± 0.015	1.911AsnPro: 1.911 ± 0.017	1.384AsnGln: 1.384 ± 0.015	1.992AsnArg: 1.992 ± 0.016	2.745AsnSer: 2.745 ± 0.019	2.142AsnThr: 2.142 ± 0.016	2.719AsnVal: 2.719 ± 0.019	0.471AsnTrp: 0.471 ± 0.007	1.147AsnTyr: 1.147 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	3.828ProAla: 3.828 ± 0.025	0.557ProCys: 0.557 ± 0.009	2.571ProAsp: 2.571 ± 0.02	3.224ProGlu: 3.224 ± 0.024	1.681ProPhe: 1.681 ± 0.017	2.631ProGly: 2.631 ± 0.02	1.15ProHis: 1.15 ± 0.014	1.865ProIle: 1.865 ± 0.016	2.309ProLys: 2.309 ± 0.019	3.953ProLeu: 3.953 ± 0.024	1.156ProMet: 1.156 ± 0.011	1.68ProAsn: 1.68 ± 0.014	2.993ProPro: 2.993 ± 0.03	1.829ProGln: 1.829 ± 0.017	2.977ProArg: 2.977 ± 0.023	4.206ProSer: 4.206 ± 0.027	3.445ProThr: 3.445 ± 0.026	3.55ProVal: 3.55 ± 0.023	0.608ProTrp: 0.608 ± 0.01	1.059ProTyr: 1.059 ± 0.013	0.001ProXaa: 0.001 ± 0.0
Gln	3.317GlnAla: 3.317 ± 0.023	0.603GlnCys: 0.603 ± 0.008	2.163GlnAsp: 2.163 ± 0.017	2.743GlnGlu: 2.743 ± 0.021	1.402GlnPhe: 1.402 ± 0.014	2.115GlnGly: 2.115 ± 0.019	1.163GlnHis: 1.163 ± 0.012	1.834GlnIle: 1.834 ± 0.017	2.118GlnLys: 2.118 ± 0.019	4.361GlnLeu: 4.361 ± 0.026	1.076GlnMet: 1.076 ± 0.012	1.36GlnAsn: 1.36 ± 0.014	1.773GlnPro: 1.773 ± 0.016	2.708GlnGln: 2.708 ± 0.03	3.123GlnArg: 3.123 ± 0.024	2.71GlnSer: 2.71 ± 0.02	2.447GlnThr: 2.447 ± 0.019	2.809GlnVal: 2.809 ± 0.021	0.599GlnTrp: 0.599 ± 0.009	1.065GlnTyr: 1.065 ± 0.012	0.0GlnXaa: 0.0 ± 0.0
Arg	4.727ArgAla: 4.727 ± 0.026	0.976ArgCys: 0.976 ± 0.013	3.274ArgAsp: 3.274 ± 0.019	4.081ArgGlu: 4.081 ± 0.029	2.418ArgPhe: 2.418 ± 0.02	3.548ArgGly: 3.548 ± 0.026	1.638ArgHis: 1.638 ± 0.014	2.726ArgIle: 2.726 ± 0.019	3.78ArgLys: 3.78 ± 0.025	5.884ArgLeu: 5.884 ± 0.032	1.603ArgMet: 1.603 ± 0.015	2.183ArgAsn: 2.183 ± 0.017	2.555ArgPro: 2.555 ± 0.021	2.979ArgGln: 2.979 ± 0.02	5.101ArgArg: 5.101 ± 0.038	4.835ArgSer: 4.835 ± 0.031	3.21ArgThr: 3.21 ± 0.021	4.443ArgVal: 4.443 ± 0.028	0.913ArgTrp: 0.913 ± 0.012	1.762ArgTyr: 1.762 ± 0.015	0.001ArgXaa: 0.001 ± 0.0
Ser	6.179SerAla: 6.179 ± 0.036	1.118SerCys: 1.118 ± 0.012	4.803SerAsp: 4.803 ± 0.029	4.398SerGlu: 4.398 ± 0.026	2.784SerPhe: 2.784 ± 0.021	5.215SerGly: 5.215 ± 0.033	1.601SerHis: 1.601 ± 0.014	3.374SerIle: 3.374 ± 0.026	4.052SerLys: 4.052 ± 0.026	6.374SerLeu: 6.374 ± 0.03	1.885SerMet: 1.885 ± 0.016	2.899SerAsn: 2.899 ± 0.023	3.958SerPro: 3.958 ± 0.029	2.698SerGln: 2.698 ± 0.02	4.585SerArg: 4.585 ± 0.03	7.993SerSer: 7.993 ± 0.053	5.662SerThr: 5.662 ± 0.032	5.316SerVal: 5.316 ± 0.026	0.952SerTrp: 0.952 ± 0.012	1.848SerTyr: 1.848 ± 0.019	0.0SerXaa: 0.0 ± 0.0
Thr	5.003ThrAla: 5.003 ± 0.029	0.952ThrCys: 0.952 ± 0.011	3.079ThrAsp: 3.079 ± 0.021	3.47ThrGlu: 3.47 ± 0.027	2.158ThrPhe: 2.158 ± 0.015	3.577ThrGly: 3.577 ± 0.021	1.27ThrHis: 1.27 ± 0.012	2.779ThrIle: 2.779 ± 0.022	3.357ThrLys: 3.357 ± 0.021	5.394ThrLeu: 5.394 ± 0.026	1.524ThrMet: 1.524 ± 0.013	2.12ThrAsn: 2.12 ± 0.017	3.71ThrPro: 3.71 ± 0.029	2.277ThrGln: 2.277 ± 0.019	3.435ThrArg: 3.435 ± 0.025	5.282ThrSer: 5.282 ± 0.031	4.438ThrThr: 4.438 ± 0.038	3.956ThrVal: 3.956 ± 0.022	0.729ThrTrp: 0.729 ± 0.011	1.486ThrTyr: 1.486 ± 0.013	0.001ThrXaa: 0.001 ± 0.0
Val	6.102ValAla: 6.102 ± 0.031	1.228ValCys: 1.228 ± 0.013	4.383ValAsp: 4.383 ± 0.026	4.727ValGlu: 4.727 ± 0.025	2.841ValPhe: 2.841 ± 0.02	3.934ValGly: 3.934 ± 0.027	1.834ValHis: 1.834 ± 0.016	3.108ValIle: 3.108 ± 0.022	3.811ValLys: 3.811 ± 0.022	6.737ValLeu: 6.737 ± 0.033	1.834ValMet: 1.834 ± 0.014	2.743ValAsn: 2.743 ± 0.018	3.383ValPro: 3.383 ± 0.025	2.764ValGln: 2.764 ± 0.021	3.957ValArg: 3.957 ± 0.027	5.242ValSer: 5.242 ± 0.03	4.202ValThr: 4.202 ± 0.024	5.7ValVal: 5.7 ± 0.033	0.909ValTrp: 0.909 ± 0.01	1.986ValTyr: 1.986 ± 0.018	0.001ValXaa: 0.001 ± 0.0
Trp	0.843TrpAla: 0.843 ± 0.011	0.228TrpCys: 0.228 ± 0.006	0.7TrpAsp: 0.7 ± 0.009	0.768TrpGlu: 0.768 ± 0.01	0.464TrpPhe: 0.464 ± 0.009	0.736TrpGly: 0.736 ± 0.012	0.315TrpHis: 0.315 ± 0.006	0.746TrpIle: 0.746 ± 0.009	0.901TrpLys: 0.901 ± 0.011	1.298TrpLeu: 1.298 ± 0.015	0.386TrpMet: 0.386 ± 0.007	0.604TrpAsn: 0.604 ± 0.009	0.443TrpPro: 0.443 ± 0.008	0.489TrpGln: 0.489 ± 0.008	0.903TrpArg: 0.903 ± 0.013	0.901TrpSer: 0.901 ± 0.01	0.759TrpThr: 0.759 ± 0.009	0.935TrpVal: 0.935 ± 0.013	0.21TrpTrp: 0.21 ± 0.005	0.393TrpTyr: 0.393 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.229TyrAla: 2.229 ± 0.017	0.612TyrCys: 0.612 ± 0.01	1.582TyrAsp: 1.582 ± 0.015	1.839TyrGlu: 1.839 ± 0.014	1.172TyrPhe: 1.172 ± 0.014	1.801TyrGly: 1.801 ± 0.017	0.815TyrHis: 0.815 ± 0.011	1.144TyrIle: 1.144 ± 0.012	1.226TyrLys: 1.226 ± 0.014	2.585TyrLeu: 2.585 ± 0.018	0.685TyrMet: 0.685 ± 0.009	1.062TyrAsn: 1.062 ± 0.014	1.224TyrPro: 1.224 ± 0.013	1.15TyrGln: 1.15 ± 0.013	1.67TyrArg: 1.67 ± 0.014	1.912TyrSer: 1.912 ± 0.016	1.514TyrThr: 1.514 ± 0.015	1.991TyrVal: 1.991 ± 0.018	0.422TyrTrp: 0.422 ± 0.007	0.941TyrTyr: 0.941 ± 0.011	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.172XaaXaa: 0.172 ± 0.028

Statistics based on 24468 proteins (8206119 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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