Simian T-cell lymphotropic virus 4

Taxonomy: Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus; Simian immunodeficiency virus

Average proteome isoelectric point is 8.05

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 4 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|W5UB23|W5UB23_SIV Gag protein OS=Simian T-cell lymphotropic virus 4 OX=1454033 PE=4 SV=1
MM1 pKa = 7.18GQTHH5 pKa = 6.52TSSPVPKK12 pKa = 10.1APRR15 pKa = 11.84GLSTHH20 pKa = 5.79HH21 pKa = 6.88WLNFLQAAYY30 pKa = 9.95RR31 pKa = 11.84LQPGPSEE38 pKa = 4.33FDD40 pKa = 2.96FHH42 pKa = 6.44QLRR45 pKa = 11.84RR46 pKa = 11.84FLKK49 pKa = 10.6LALQTPVWLNPIDD62 pKa = 4.11YY63 pKa = 10.45SLLASLIPKK72 pKa = 8.97GYY74 pKa = 8.47PGRR77 pKa = 11.84VTEE80 pKa = 4.58IVNILLRR87 pKa = 11.84AHH89 pKa = 7.48PPPSAPAISMPSATGPAPAPQPQEE113 pKa = 3.66AHH115 pKa = 6.01TPPPYY120 pKa = 10.61AEE122 pKa = 4.25PAALQCLPIMHH133 pKa = 6.42SHH135 pKa = 6.84GAPSSHH141 pKa = 6.86RR142 pKa = 11.84PWQMKK147 pKa = 9.77DD148 pKa = 2.99LQAIKK153 pKa = 10.63QEE155 pKa = 4.28ISTSAPGSPQFMQTIRR171 pKa = 11.84LAIQQFDD178 pKa = 3.75PTAKK182 pKa = 10.22DD183 pKa = 3.33LHH185 pKa = 7.15DD186 pKa = 4.57LLQYY190 pKa = 10.65LCSSLIVSLHH200 pKa = 5.4HH201 pKa = 6.11QQLQALIAEE210 pKa = 4.59AEE212 pKa = 4.34TRR214 pKa = 11.84GLTGYY219 pKa = 10.95NPMAGPLRR227 pKa = 11.84VQANNPAQQGLRR239 pKa = 11.84RR240 pKa = 11.84EE241 pKa = 4.3YY242 pKa = 10.63QSLWLAAFAALPGNTRR258 pKa = 11.84DD259 pKa = 4.02PSWAAILQGLEE270 pKa = 3.8EE271 pKa = 4.83PYY273 pKa = 10.48CAFVEE278 pKa = 4.3RR279 pKa = 11.84LNVALDD285 pKa = 3.32NGLPEE290 pKa = 4.52GTPKK294 pKa = 10.76EE295 pKa = 4.23PILRR299 pKa = 11.84SLAYY303 pKa = 10.58SNANKK308 pKa = 9.97EE309 pKa = 4.36CQKK312 pKa = 10.72LLQARR317 pKa = 11.84GHH319 pKa = 5.59TNSPLGEE326 pKa = 4.11MLRR329 pKa = 11.84ACQAWTPKK337 pKa = 10.79DD338 pKa = 3.32KK339 pKa = 11.14TKK341 pKa = 11.11VLVVQPRR348 pKa = 11.84KK349 pKa = 8.11TPPTQPCFRR358 pKa = 11.84CGKK361 pKa = 8.35VGHH364 pKa = 6.73WSRR367 pKa = 11.84DD368 pKa = 3.52CTQPRR373 pKa = 11.84PPPGPCPLCQDD384 pKa = 3.51PSHH387 pKa = 7.13WKK389 pKa = 9.9RR390 pKa = 11.84DD391 pKa = 3.74CPQLKK396 pKa = 8.55TPPEE400 pKa = 4.06VEE402 pKa = 4.23EE403 pKa = 4.73PLLADD408 pKa = 5.0LPALLPEE415 pKa = 4.79EE416 pKa = 4.49KK417 pKa = 10.37NSPGGEE423 pKa = 3.95NN424 pKa = 3.13

Molecular weight: 46.72 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|W5UB23|W5UB23_SIV Gag protein OS=Simian T-cell lymphotropic virus 4 OX=1454033 PE=4 SV=1
MM1 pKa = 7.9PGGPLLTGGPPGPDD15 pKa = 2.93PVIPGDD21 pKa = 3.96HH22 pKa = 6.83PCSHH26 pKa = 7.55RR27 pKa = 11.84LRR29 pKa = 11.84TSSRR33 pKa = 11.84APRR36 pKa = 11.84GQPVSFKK43 pKa = 10.47PEE45 pKa = 3.71RR46 pKa = 11.84LQALIDD52 pKa = 4.03LVSKK56 pKa = 10.73ALEE59 pKa = 4.32AGHH62 pKa = 6.72IEE64 pKa = 4.71PYY66 pKa = 10.27SGPGNNPVFPVKK78 pKa = 10.43KK79 pKa = 10.1PNGKK83 pKa = 8.28WRR85 pKa = 11.84FIHH88 pKa = 7.35DD89 pKa = 4.17LRR91 pKa = 11.84ATNAITTTLASPSPGPPDD109 pKa = 3.82LTSLPQALPHH119 pKa = 6.32LQTIDD124 pKa = 3.2LTDD127 pKa = 3.66AFFQIPLPKK136 pKa = 10.01RR137 pKa = 11.84FQPYY141 pKa = 9.14FAFTIPQPLNHH152 pKa = 6.83GPGSRR157 pKa = 11.84YY158 pKa = 9.81AWTVLPQGFKK168 pKa = 10.78NSPTLFEE175 pKa = 3.98QQLASVLGPARR186 pKa = 11.84KK187 pKa = 9.45AFPASVIVQYY197 pKa = 10.61MDD199 pKa = 6.41DD200 pKa = 4.5ILLACPSQHH209 pKa = 6.76EE210 pKa = 4.37LDD212 pKa = 3.73QLATLTAQLLSSHH225 pKa = 6.53GLPVSQEE232 pKa = 3.64KK233 pKa = 7.52TQRR236 pKa = 11.84TPGKK240 pKa = 9.59IHH242 pKa = 6.56FLGQIIHH249 pKa = 7.53PDD251 pKa = 3.42HH252 pKa = 6.45ITYY255 pKa = 7.62EE256 pKa = 4.28TTPTIPIKK264 pKa = 10.73AHH266 pKa = 4.78WTLTEE271 pKa = 3.96LQTLLGEE278 pKa = 4.4LQWVSKK284 pKa = 7.78GTPVLRR290 pKa = 11.84EE291 pKa = 4.21HH292 pKa = 6.65LHH294 pKa = 5.97CLYY297 pKa = 10.77SALRR301 pKa = 11.84GLKK304 pKa = 10.16DD305 pKa = 3.4PRR307 pKa = 11.84DD308 pKa = 4.36TITLRR313 pKa = 11.84HH314 pKa = 5.6PHH316 pKa = 6.1LHH318 pKa = 6.37ALHH321 pKa = 6.95NIQQALHH328 pKa = 5.96HH329 pKa = 6.16NCRR332 pKa = 11.84GRR334 pKa = 11.84LDD336 pKa = 3.41STLPLLGLIFLSPSGTTSVLFQTNHH361 pKa = 4.91KK362 pKa = 9.19WPLVWLHH369 pKa = 6.07TPHH372 pKa = 7.49PPTSLCPWGHH382 pKa = 6.46ILACTVLTLDD392 pKa = 4.64KK393 pKa = 11.05YY394 pKa = 11.06ALQHH398 pKa = 5.89YY399 pKa = 8.05GQLCKK404 pKa = 10.53SFHH407 pKa = 6.9HH408 pKa = 6.28NMSTQALHH416 pKa = 7.19DD417 pKa = 3.9FVKK420 pKa = 10.68NSSHH424 pKa = 6.87PSVAILIHH432 pKa = 6.0HH433 pKa = 6.34MHH435 pKa = 7.12RR436 pKa = 11.84FCDD439 pKa = 4.23LGRR442 pKa = 11.84QPPGPWRR449 pKa = 11.84TLLQLPALLRR459 pKa = 11.84EE460 pKa = 4.27PQLLRR465 pKa = 11.84PAFSLSPVVIDD476 pKa = 4.19QAPCLFSDD484 pKa = 5.36GSPQKK489 pKa = 10.3AAYY492 pKa = 9.03VIWDD496 pKa = 3.85KK497 pKa = 11.57VILSQRR503 pKa = 11.84SVPLPPHH510 pKa = 6.73ANNSAQKK517 pKa = 10.53GEE519 pKa = 4.23LVGLLLGLQAAQPWPSLNIFLDD541 pKa = 3.7SKK543 pKa = 10.79FLIRR547 pKa = 11.84YY548 pKa = 6.81LQSLASGAFQGSSTHH563 pKa = 6.27HH564 pKa = 6.97RR565 pKa = 11.84LQASLPTLLQGKK577 pKa = 8.07VVYY580 pKa = 10.03LHH582 pKa = 6.24HH583 pKa = 6.65TRR585 pKa = 11.84SHH587 pKa = 5.5TQLPDD592 pKa = 4.75PISTLNEE599 pKa = 4.05YY600 pKa = 9.83TDD602 pKa = 3.86SLIVAPVTPLKK613 pKa = 10.79PEE615 pKa = 4.08GLHH618 pKa = 7.2ALTHH622 pKa = 6.61CNQQALVSHH631 pKa = 6.93GATPAQAKK639 pKa = 9.57QLVQACRR646 pKa = 11.84TCQIINPQHH655 pKa = 5.99HH656 pKa = 6.55MPRR659 pKa = 11.84GHH661 pKa = 6.78IRR663 pKa = 11.84RR664 pKa = 11.84GHH666 pKa = 5.89FPNHH670 pKa = 4.51TWQGDD675 pKa = 3.81VTHH678 pKa = 7.23LKK680 pKa = 10.15HH681 pKa = 6.96KK682 pKa = 8.24RR683 pKa = 11.84TRR685 pKa = 11.84YY686 pKa = 9.31CLHH689 pKa = 5.81VWVDD693 pKa = 3.66TFSGAVSCVCKK704 pKa = 10.57KK705 pKa = 10.76KK706 pKa = 9.28EE707 pKa = 4.11TSSDD711 pKa = 3.8LIKK714 pKa = 10.12TLLHH718 pKa = 6.78AISVLGKK725 pKa = 8.83PFSVNTDD732 pKa = 2.95NGPAYY737 pKa = 10.6LSQEE741 pKa = 3.77FHH743 pKa = 6.62EE744 pKa = 5.68FCTTLCIKK752 pKa = 10.43HH753 pKa = 5.78STHH756 pKa = 6.28IPYY759 pKa = 10.59NPTSSGLVEE768 pKa = 4.14RR769 pKa = 11.84TNGILKK775 pKa = 8.95TLLYY779 pKa = 10.34KK780 pKa = 10.82YY781 pKa = 10.56FLDD784 pKa = 5.11HH785 pKa = 7.63PDD787 pKa = 4.09LPLEE791 pKa = 4.31SAVSKK796 pKa = 10.83ALWTINHH803 pKa = 6.43LNVMRR808 pKa = 11.84PCGKK812 pKa = 8.22TRR814 pKa = 11.84WQLHH818 pKa = 5.21HH819 pKa = 7.01TPPLPPISEE828 pKa = 4.79SIQTTPTGLHH838 pKa = 5.33WYY840 pKa = 9.23YY841 pKa = 11.24YY842 pKa = 7.96KK843 pKa = 10.59TPGLTNQRR851 pKa = 11.84WKK853 pKa = 11.34GPVQSLQEE861 pKa = 3.96AAGAALLQVSDD872 pKa = 5.82GSPQWIPWRR881 pKa = 11.84LLKK884 pKa = 9.93KK885 pKa = 7.83TVCPKK890 pKa = 10.44PDD892 pKa = 3.73DD893 pKa = 4.54PEE895 pKa = 4.41PAGHH899 pKa = 6.68VEE901 pKa = 4.13TDD903 pKa = 3.6HH904 pKa = 5.88QHH906 pKa = 6.15HH907 pKa = 6.59GG908 pKa = 3.53

Molecular weight: 101.0 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

4

0

4

2030

213

908

507.5

56.02

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.995 ± 0.837

2.463 ± 0.241

3.35 ± 0.177

3.054 ± 0.583

2.611 ± 0.262

5.764 ± 0.387

4.483 ± 1.133

4.286 ± 0.367

3.744 ± 0.416

13.547 ± 0.471

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

0.936 ± 0.248

3.005 ± 0.147

11.182 ± 1.005

6.355 ± 0.343

4.631 ± 0.31

7.734 ± 0.813

6.798 ± 0.647

4.631 ± 0.448

2.02 ± 0.207

2.414 ± 0.354
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski