Dugbe virus (isolate ArD44313) (DUGV)

Taxonomy: Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina; Ellioviricetes; Bunyavirales; Nairoviridae; Orthonairovirus; Dugbe orthonairovirus

Average proteome isoelectric point is 6.92

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 3 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
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Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>sp|Q8V336|NCAP_DUGBA Nucleoprotein OS=Dugbe virus (isolate ArD44313) OX=766194 GN=N PE=3 SV=1
MM1 pKa = 8.11DD2 pKa = 5.35FLDD5 pKa = 3.6SLIWEE10 pKa = 4.19RR11 pKa = 11.84VVDD14 pKa = 3.91EE15 pKa = 4.61QYY17 pKa = 9.26ITNPTFCVSDD27 pKa = 3.67YY28 pKa = 11.27FEE30 pKa = 5.45VIRR33 pKa = 11.84QPGDD37 pKa = 3.36GNCFYY42 pKa = 11.1HH43 pKa = 7.58SIAEE47 pKa = 4.16LFFDD51 pKa = 4.17VKK53 pKa = 10.3TPSSFRR59 pKa = 11.84KK60 pKa = 9.81VKK62 pKa = 10.31EE63 pKa = 3.92HH64 pKa = 6.3LQLAAEE70 pKa = 4.66VYY72 pKa = 10.9YY73 pKa = 9.74DD74 pKa = 3.95TEE76 pKa = 4.81PEE78 pKa = 3.95AVGTGISKK86 pKa = 10.84DD87 pKa = 3.61EE88 pKa = 4.3YY89 pKa = 10.42IKK91 pKa = 11.16VAMKK95 pKa = 10.51DD96 pKa = 3.81NEE98 pKa = 4.39WGGSLEE104 pKa = 4.07ASMLSKK110 pKa = 10.55HH111 pKa = 5.86LQTTIILWVVNSTEE125 pKa = 4.04QVTAAIKK132 pKa = 10.06FGPGRR137 pKa = 11.84VSTALNLMHH146 pKa = 7.18VGRR149 pKa = 11.84THH151 pKa = 7.29FDD153 pKa = 2.89ALRR156 pKa = 11.84IIEE159 pKa = 4.1QLEE162 pKa = 3.97NNQPQDD168 pKa = 3.43RR169 pKa = 11.84NRR171 pKa = 11.84LDD173 pKa = 3.13IADD176 pKa = 5.36RR177 pKa = 11.84IAAAEE182 pKa = 4.25VYY184 pKa = 9.73VRR186 pKa = 11.84QSIEE190 pKa = 4.53DD191 pKa = 3.64NLQEE195 pKa = 5.95DD196 pKa = 4.35EE197 pKa = 4.54FFDD200 pKa = 3.97YY201 pKa = 10.99ARR203 pKa = 11.84EE204 pKa = 4.06DD205 pKa = 4.11EE206 pKa = 4.2ISEE209 pKa = 4.34DD210 pKa = 3.49VSAPGGSRR218 pKa = 11.84EE219 pKa = 4.02ATEE222 pKa = 4.26LKK224 pKa = 10.49KK225 pKa = 10.7KK226 pKa = 10.73AILLNKK232 pKa = 7.28TVKK235 pKa = 10.28RR236 pKa = 11.84GEE238 pKa = 4.32NIPIRR243 pKa = 11.84VGRR246 pKa = 11.84VLDD249 pKa = 4.06CLFSCKK255 pKa = 9.67IAVSLDD261 pKa = 3.04EE262 pKa = 4.44GLLYY266 pKa = 10.58LRR268 pKa = 11.84PEE270 pKa = 4.13TRR272 pKa = 11.84EE273 pKa = 3.95SEE275 pKa = 4.13ATSISLRR282 pKa = 11.84QLGHH286 pKa = 6.93KK287 pKa = 10.28LLTRR291 pKa = 11.84DD292 pKa = 3.13RR293 pKa = 11.84HH294 pKa = 6.29IKK296 pKa = 9.34MEE298 pKa = 4.06YY299 pKa = 10.09ARR301 pKa = 11.84SKK303 pKa = 11.09LYY305 pKa = 8.83VTRR308 pKa = 11.84DD309 pKa = 3.78LIDD312 pKa = 3.76HH313 pKa = 7.01LDD315 pKa = 3.13IGGLLRR321 pKa = 11.84SSFPGLGLEE330 pKa = 4.93RR331 pKa = 11.84YY332 pKa = 8.8IQLLHH337 pKa = 6.63SEE339 pKa = 4.45LVLDD343 pKa = 4.45LVTVVLAVLLSTFLYY358 pKa = 10.68GSNNKK363 pKa = 9.08NKK365 pKa = 10.19KK366 pKa = 9.0QFITNCLLNTKK377 pKa = 10.29LSGKK381 pKa = 9.89RR382 pKa = 11.84VFKK385 pKa = 10.78ALSKK389 pKa = 10.22LTGQMLYY396 pKa = 8.66RR397 pKa = 11.84TPKK400 pKa = 8.32RR401 pKa = 11.84AVSIVSQEE409 pKa = 4.19LYY411 pKa = 10.6GKK413 pKa = 10.94LMLKK417 pKa = 10.0VKK419 pKa = 10.82NNLEE423 pKa = 3.97GMGPISMLALRR434 pKa = 11.84NLNFDD439 pKa = 3.56NMQLQDD445 pKa = 4.19YY446 pKa = 10.94LEE448 pKa = 4.5MLSEE452 pKa = 4.02MSKK455 pKa = 10.17IDD457 pKa = 3.66NSDD460 pKa = 2.87VEE462 pKa = 4.47YY463 pKa = 9.07THH465 pKa = 7.96RR466 pKa = 11.84EE467 pKa = 3.51ISDD470 pKa = 3.16LHH472 pKa = 5.72TLVEE476 pKa = 4.51RR477 pKa = 11.84LSKK480 pKa = 10.25LQKK483 pKa = 10.2SQDD486 pKa = 3.63VNEE489 pKa = 4.06LKK491 pKa = 10.65LWFKK495 pKa = 11.37EE496 pKa = 3.98EE497 pKa = 4.17VLTKK501 pKa = 10.26RR502 pKa = 11.84SQRR505 pKa = 11.84SVGNAFEE512 pKa = 4.91FLINDD517 pKa = 3.51YY518 pKa = 10.51FKK520 pKa = 11.17KK521 pKa = 10.13KK522 pKa = 10.59DD523 pKa = 3.07IMKK526 pKa = 10.1FVSTSGKK533 pKa = 10.35ASSTGNIGNVLSYY546 pKa = 11.27AHH548 pKa = 6.72NLYY551 pKa = 10.46LSKK554 pKa = 10.84EE555 pKa = 4.35SLRR558 pKa = 11.84MTSEE562 pKa = 4.87DD563 pKa = 3.35VTQLLIEE570 pKa = 3.99IRR572 pKa = 11.84KK573 pKa = 8.47LHH575 pKa = 6.36KK576 pKa = 10.67LQGDD580 pKa = 4.05LSIEE584 pKa = 3.99PVAIICDD591 pKa = 3.49KK592 pKa = 11.52LEE594 pKa = 4.08DD595 pKa = 3.59QFRR598 pKa = 11.84KK599 pKa = 9.94LFRR602 pKa = 11.84EE603 pKa = 4.1LPEE606 pKa = 4.38EE607 pKa = 4.45CSSEE611 pKa = 4.09CQTLFNDD618 pKa = 3.35IRR620 pKa = 11.84NSPSHH625 pKa = 5.47SVAWKK630 pKa = 9.27HH631 pKa = 5.66ALRR634 pKa = 11.84LKK636 pKa = 8.56GTAYY640 pKa = 10.25EE641 pKa = 4.58GMFAKK646 pKa = 10.39QYY648 pKa = 7.9GWSYY652 pKa = 10.22ISEE655 pKa = 4.76DD656 pKa = 3.42IKK658 pKa = 11.12PSLTMIVQTLFPEE671 pKa = 4.28SFEE674 pKa = 4.44AFLDD678 pKa = 3.85RR679 pKa = 11.84TQLHH683 pKa = 6.67PEE685 pKa = 4.03FRR687 pKa = 11.84DD688 pKa = 3.47LTPDD692 pKa = 3.17YY693 pKa = 11.38ALTQKK698 pKa = 10.25IFFPRR703 pKa = 11.84NTIPRR708 pKa = 11.84TEE710 pKa = 3.8NRR712 pKa = 11.84QLAIDD717 pKa = 3.84VSLEE721 pKa = 3.91GSVEE725 pKa = 3.83AVPIVEE731 pKa = 4.44KK732 pKa = 10.96RR733 pKa = 11.84MFPLPEE739 pKa = 4.01VPIGEE744 pKa = 4.5ANSISRR750 pKa = 11.84VMNIFKK756 pKa = 10.41EE757 pKa = 4.11KK758 pKa = 10.35RR759 pKa = 11.84EE760 pKa = 3.78EE761 pKa = 4.12SMQKK765 pKa = 10.39KK766 pKa = 10.08LEE768 pKa = 4.12HH769 pKa = 6.92DD770 pKa = 3.74RR771 pKa = 11.84QAEE774 pKa = 4.05ANRR777 pKa = 11.84LKK779 pKa = 10.9SAGLSASKK787 pKa = 10.85AEE789 pKa = 4.06QEE791 pKa = 4.64VCNSAQDD798 pKa = 3.34RR799 pKa = 11.84KK800 pKa = 10.15EE801 pKa = 3.98EE802 pKa = 4.18KK803 pKa = 10.37EE804 pKa = 4.12RR805 pKa = 11.84TTEE808 pKa = 3.82PAGKK812 pKa = 7.78QQRR815 pKa = 11.84TEE817 pKa = 3.89DD818 pKa = 3.56LVVIEE823 pKa = 4.73GNQDD827 pKa = 3.31EE828 pKa = 5.16GDD830 pKa = 3.8SDD832 pKa = 3.86PQKK835 pKa = 10.99KK836 pKa = 9.77VDD838 pKa = 3.55EE839 pKa = 4.31KK840 pKa = 10.38TVPGEE845 pKa = 4.25SKK847 pKa = 9.91QHH849 pKa = 5.73SKK851 pKa = 11.12SSGSSSTNQMSQKK864 pKa = 10.14VVDD867 pKa = 4.12VPSVEE872 pKa = 4.63DD873 pKa = 4.46SSDD876 pKa = 3.44QAPGDD881 pKa = 3.84FPDD884 pKa = 3.11YY885 pKa = 10.7GYY887 pKa = 10.42YY888 pKa = 10.2FKK890 pKa = 10.74RR891 pKa = 11.84IVMDD895 pKa = 3.6EE896 pKa = 4.15SGTVLTEE903 pKa = 3.58EE904 pKa = 4.13AQLEE908 pKa = 4.17KK909 pKa = 10.7RR910 pKa = 11.84QLLFIEE916 pKa = 4.61VGYY919 pKa = 8.12QTDD922 pKa = 3.4VDD924 pKa = 4.28GKK926 pKa = 9.43ITTDD930 pKa = 3.24YY931 pKa = 11.02KK932 pKa = 10.12KK933 pKa = 9.98WKK935 pKa = 10.23DD936 pKa = 3.19ILRR939 pKa = 11.84LLEE942 pKa = 4.34LLNIKK947 pKa = 10.37CSFIACADD955 pKa = 3.91CSSTPSNNWWISEE968 pKa = 4.05DD969 pKa = 3.9KK970 pKa = 11.19VRR972 pKa = 11.84LLKK975 pKa = 10.91NSISHH980 pKa = 7.1LFSKK984 pKa = 9.22LTQNSPADD992 pKa = 3.43VTDD995 pKa = 3.48IVVGSISTQKK1005 pKa = 9.51VRR1007 pKa = 11.84SYY1009 pKa = 10.75LKK1011 pKa = 10.68SGTATKK1017 pKa = 10.18TPISLKK1023 pKa = 10.41DD1024 pKa = 3.64VQEE1027 pKa = 4.37TWSKK1031 pKa = 9.33MKK1033 pKa = 10.44DD1034 pKa = 3.55YY1035 pKa = 10.69IVNRR1039 pKa = 11.84PTGISLNKK1047 pKa = 9.39EE1048 pKa = 3.94LVGALYY1054 pKa = 10.36QGLVEE1059 pKa = 4.26GAIISKK1065 pKa = 10.28EE1066 pKa = 3.96GTVNLIQMLKK1076 pKa = 10.44DD1077 pKa = 3.1KK1078 pKa = 10.32QEE1080 pKa = 4.58RR1081 pKa = 11.84ITDD1084 pKa = 3.44EE1085 pKa = 4.18FEE1087 pKa = 3.86RR1088 pKa = 11.84TKK1090 pKa = 10.86LKK1092 pKa = 11.0HH1093 pKa = 5.76EE1094 pKa = 4.32VNEE1097 pKa = 4.18DD1098 pKa = 3.36VKK1100 pKa = 10.48TSEE1103 pKa = 4.24KK1104 pKa = 10.91LLLGWLMEE1112 pKa = 4.49DD1113 pKa = 4.9LKK1115 pKa = 11.42GCRR1118 pKa = 11.84CMGCLTKK1125 pKa = 10.26IKK1127 pKa = 9.82EE1128 pKa = 4.38LSEE1131 pKa = 4.28SMSVNQDD1138 pKa = 2.86RR1139 pKa = 11.84LEE1141 pKa = 4.08YY1142 pKa = 10.8LSTNCQTKK1150 pKa = 8.11SHH1152 pKa = 6.25CTEE1155 pKa = 3.72CHH1157 pKa = 5.56PRR1159 pKa = 11.84SLEE1162 pKa = 3.54YY1163 pKa = 10.85RR1164 pKa = 11.84NISNVDD1170 pKa = 2.98NRR1172 pKa = 11.84VPSMQRR1178 pKa = 11.84VSHH1181 pKa = 5.93SRR1183 pKa = 11.84NEE1185 pKa = 4.12GFEE1188 pKa = 4.26DD1189 pKa = 3.69TNEE1192 pKa = 4.14TLTEE1196 pKa = 4.08LDD1198 pKa = 3.22RR1199 pKa = 11.84LVRR1202 pKa = 11.84LTLPGKK1208 pKa = 6.82TEE1210 pKa = 3.49KK1211 pKa = 10.24EE1212 pKa = 3.73RR1213 pKa = 11.84RR1214 pKa = 11.84VKK1216 pKa = 10.81RR1217 pKa = 11.84NVEE1220 pKa = 3.64GLIRR1224 pKa = 11.84FMMQQSSLDD1233 pKa = 4.16CIKK1236 pKa = 10.69LPSGQIIAHH1245 pKa = 6.08RR1246 pKa = 11.84CSKK1249 pKa = 10.34KK1250 pKa = 10.48FKK1252 pKa = 9.9NSSEE1256 pKa = 4.2AEE1258 pKa = 4.21EE1259 pKa = 4.23KK1260 pKa = 10.69CNEE1263 pKa = 3.8RR1264 pKa = 11.84FEE1266 pKa = 5.45RR1267 pKa = 11.84LMKK1270 pKa = 10.29EE1271 pKa = 3.96LSEE1274 pKa = 4.27QKK1276 pKa = 10.2LKK1278 pKa = 10.61PYY1280 pKa = 9.87SDD1282 pKa = 3.89HH1283 pKa = 5.51VRR1285 pKa = 11.84KK1286 pKa = 8.48TITSSLKK1293 pKa = 9.7KK1294 pKa = 8.79TDD1296 pKa = 3.18KK1297 pKa = 10.84QAGSKK1302 pKa = 10.35CAVPRR1307 pKa = 11.84LWLEE1311 pKa = 3.62TLIRR1315 pKa = 11.84DD1316 pKa = 3.96LRR1318 pKa = 11.84VPTKK1322 pKa = 10.78DD1323 pKa = 3.73EE1324 pKa = 4.7EE1325 pKa = 4.04ILLNIRR1331 pKa = 11.84TSMQSKK1337 pKa = 9.57TNFIRR1342 pKa = 11.84NNDD1345 pKa = 3.39KK1346 pKa = 11.21LIIRR1350 pKa = 11.84SNKK1353 pKa = 9.31EE1354 pKa = 3.14IADD1357 pKa = 3.69YY1358 pKa = 11.58LEE1360 pKa = 4.31TKK1362 pKa = 10.4RR1363 pKa = 11.84KK1364 pKa = 9.67NLLSEE1369 pKa = 4.18KK1370 pKa = 10.5ASDD1373 pKa = 4.16KK1374 pKa = 10.87IFSSDD1379 pKa = 3.71CILFKK1384 pKa = 10.85EE1385 pKa = 4.82VIAEE1389 pKa = 3.98ALRR1392 pKa = 11.84RR1393 pKa = 11.84YY1394 pKa = 10.25YY1395 pKa = 9.33STPYY1399 pKa = 10.01EE1400 pKa = 4.41GVPEE1404 pKa = 4.47TIVKK1408 pKa = 10.05LINFLCTFGWFQEE1421 pKa = 4.14VVLYY1425 pKa = 10.75SKK1427 pKa = 10.29ICEE1430 pKa = 4.21TFLRR1434 pKa = 11.84CCTEE1438 pKa = 4.2FSRR1441 pKa = 11.84SGIKK1445 pKa = 9.71LVKK1448 pKa = 9.97VRR1450 pKa = 11.84HH1451 pKa = 6.44CDD1453 pKa = 3.18TNLSIKK1459 pKa = 10.53LPSNKK1464 pKa = 9.18KK1465 pKa = 10.52EE1466 pKa = 3.96NMLCCLYY1473 pKa = 10.59DD1474 pKa = 3.96KK1475 pKa = 11.38NMSLLKK1481 pKa = 10.88GPFFLNRR1488 pKa = 11.84RR1489 pKa = 11.84QAILGSAYY1497 pKa = 9.72PYY1499 pKa = 10.72ILITLYY1505 pKa = 10.37IQVLQQHH1512 pKa = 6.27RR1513 pKa = 11.84CLEE1516 pKa = 4.29VLNSVNDD1523 pKa = 3.76RR1524 pKa = 11.84VVGNINTCTSNLLNTVKK1541 pKa = 11.01AEE1543 pKa = 3.97LTLVNSGLFEE1553 pKa = 3.91KK1554 pKa = 10.33AYY1556 pKa = 10.0EE1557 pKa = 4.32CRR1559 pKa = 11.84TEE1561 pKa = 3.78QCRR1564 pKa = 11.84LGGNFLNRR1572 pKa = 11.84SSRR1575 pKa = 11.84DD1576 pKa = 3.38HH1577 pKa = 6.95FISTVSGLNVVYY1589 pKa = 10.27GALIKK1594 pKa = 10.97DD1595 pKa = 3.56NLLANSQPQNKK1606 pKa = 7.91QLQMLRR1612 pKa = 11.84FGMLCGLSRR1621 pKa = 11.84LSSALEE1627 pKa = 3.89LGKK1630 pKa = 10.61KK1631 pKa = 10.53FSTSCRR1637 pKa = 11.84RR1638 pKa = 11.84IEE1640 pKa = 4.11DD1641 pKa = 3.75NIMRR1645 pKa = 11.84LYY1647 pKa = 10.19LQSTIYY1653 pKa = 10.2SANRR1657 pKa = 11.84DD1658 pKa = 3.12VSQNVQNWKK1667 pKa = 9.24MKK1669 pKa = 10.1DD1670 pKa = 3.43LCPDD1674 pKa = 2.95ITIPCFSVYY1683 pKa = 10.93GLFVNSDD1690 pKa = 3.28RR1691 pKa = 11.84QRR1693 pKa = 11.84IFDD1696 pKa = 3.95IYY1698 pKa = 11.02NVHH1701 pKa = 6.99IYY1703 pKa = 9.84NKK1705 pKa = 10.3EE1706 pKa = 3.49MDD1708 pKa = 4.65NFDD1711 pKa = 3.93EE1712 pKa = 4.87GCITVLEE1719 pKa = 4.52EE1720 pKa = 3.42TAEE1723 pKa = 3.93RR1724 pKa = 11.84HH1725 pKa = 5.15MLWEE1729 pKa = 4.78LDD1731 pKa = 3.75LLRR1734 pKa = 11.84SLEE1737 pKa = 3.86GDD1739 pKa = 3.38TRR1741 pKa = 11.84DD1742 pKa = 3.29VRR1744 pKa = 11.84AARR1747 pKa = 11.84LLLGCPNIRR1756 pKa = 11.84KK1757 pKa = 8.52ATDD1760 pKa = 3.18KK1761 pKa = 11.27DD1762 pKa = 3.92GNRR1765 pKa = 11.84LMKK1768 pKa = 10.54KK1769 pKa = 10.34GITDD1773 pKa = 3.34DD1774 pKa = 3.27WRR1776 pKa = 11.84EE1777 pKa = 3.96EE1778 pKa = 4.03AGSDD1782 pKa = 3.31SSSISGRR1789 pKa = 11.84RR1790 pKa = 11.84SYY1792 pKa = 11.24ASSGTRR1798 pKa = 11.84VKK1800 pKa = 11.41SMFGKK1805 pKa = 10.54YY1806 pKa = 9.79NSSQKK1811 pKa = 10.31PFEE1814 pKa = 4.64LKK1816 pKa = 10.44PGLEE1820 pKa = 4.3VVNDD1824 pKa = 4.1PLHH1827 pKa = 7.18DD1828 pKa = 3.96YY1829 pKa = 10.0KK1830 pKa = 11.09QAVQDD1835 pKa = 3.72SFCYY1839 pKa = 10.07SEE1841 pKa = 4.08YY1842 pKa = 10.59TPNTEE1847 pKa = 5.44SVLKK1851 pKa = 10.62DD1852 pKa = 3.79CIHH1855 pKa = 7.86IIRR1858 pKa = 11.84TNPSHH1863 pKa = 6.6TMGSYY1868 pKa = 10.66EE1869 pKa = 4.82LIQAVTEE1876 pKa = 4.05NARR1879 pKa = 11.84RR1880 pKa = 11.84KK1881 pKa = 9.61YY1882 pKa = 9.61PPEE1885 pKa = 4.16NIEE1888 pKa = 4.6RR1889 pKa = 11.84ARR1891 pKa = 11.84KK1892 pKa = 9.43DD1893 pKa = 3.2PKK1895 pKa = 9.55NWVSISEE1902 pKa = 4.28VTEE1905 pKa = 3.95TTSIVSQPRR1914 pKa = 11.84THH1916 pKa = 7.16FMLKK1920 pKa = 10.13DD1921 pKa = 3.65CYY1923 pKa = 10.46KK1924 pKa = 10.8VLLGTEE1930 pKa = 3.87NKK1932 pKa = 10.25KK1933 pKa = 9.4IVKK1936 pKa = 8.42MLRR1939 pKa = 11.84GKK1941 pKa = 9.87LKK1943 pKa = 10.61KK1944 pKa = 10.17LGAMRR1949 pKa = 11.84TDD1951 pKa = 3.14IEE1953 pKa = 4.36IGKK1956 pKa = 9.58KK1957 pKa = 10.19DD1958 pKa = 4.18CLDD1961 pKa = 3.96LLTTVDD1967 pKa = 4.22GLSEE1971 pKa = 4.18EE1972 pKa = 4.08QCKK1975 pKa = 10.95NIVNGIFEE1983 pKa = 4.29PSKK1986 pKa = 10.48LSFYY1990 pKa = 10.07HH1991 pKa = 6.7WKK1993 pKa = 10.5DD1994 pKa = 3.35LLKK1997 pKa = 10.77KK1998 pKa = 9.78EE1999 pKa = 4.11LSEE2002 pKa = 5.11VLLTDD2007 pKa = 3.89DD2008 pKa = 5.2GNYY2011 pKa = 9.29IYY2013 pKa = 10.69CWLKK2017 pKa = 9.58TLSSMVKK2024 pKa = 10.09HH2025 pKa = 5.86SLKK2028 pKa = 10.24KK2029 pKa = 10.24DD2030 pKa = 3.2LRR2032 pKa = 11.84FMTGKK2037 pKa = 10.13NSLDD2041 pKa = 3.26IKK2043 pKa = 10.91PEE2045 pKa = 3.7MFTDD2049 pKa = 3.93EE2050 pKa = 4.97EE2051 pKa = 4.65YY2052 pKa = 10.95SALNIMKK2059 pKa = 10.47LEE2061 pKa = 3.98LLGEE2065 pKa = 4.31HH2066 pKa = 6.76TDD2068 pKa = 4.81GIQGKK2073 pKa = 7.56TDD2075 pKa = 3.71FLLSSWKK2082 pKa = 10.28KK2083 pKa = 9.9CALKK2087 pKa = 10.41PKK2089 pKa = 9.57EE2090 pKa = 4.14GQSILNVGLNSLAALHH2106 pKa = 7.21DD2107 pKa = 3.89EE2108 pKa = 4.97LYY2110 pKa = 10.59DD2111 pKa = 3.6IRR2113 pKa = 11.84LQHH2116 pKa = 7.21LEE2118 pKa = 3.61LTRR2121 pKa = 11.84IKK2123 pKa = 10.64KK2124 pKa = 9.25EE2125 pKa = 3.77NPTVSFTKK2133 pKa = 10.63EE2134 pKa = 3.59EE2135 pKa = 4.1ILVKK2139 pKa = 10.44RR2140 pKa = 11.84LEE2142 pKa = 4.06KK2143 pKa = 11.06GFLNKK2148 pKa = 9.82YY2149 pKa = 9.05KK2150 pKa = 10.46KK2151 pKa = 10.43EE2152 pKa = 3.84VMEE2155 pKa = 4.11AVNLIFYY2162 pKa = 10.03CCLTAPWCLHH2172 pKa = 5.18YY2173 pKa = 10.66KK2174 pKa = 10.27SLEE2177 pKa = 4.21AYY2179 pKa = 10.04LVRR2182 pKa = 11.84HH2183 pKa = 5.63PEE2185 pKa = 3.76ILEE2188 pKa = 4.19TEE2190 pKa = 4.4CIKK2193 pKa = 11.15EE2194 pKa = 3.86NDD2196 pKa = 3.68IPLLDD2201 pKa = 3.9LTVTSLIRR2209 pKa = 11.84SLIDD2213 pKa = 4.54DD2214 pKa = 4.05IEE2216 pKa = 5.32GEE2218 pKa = 4.37SSFNDD2223 pKa = 3.15SSDD2226 pKa = 2.85IKK2228 pKa = 11.13VRR2230 pKa = 11.84FAVKK2234 pKa = 10.36YY2235 pKa = 10.63LITLFTANGEE2245 pKa = 4.14PFSLSLNDD2253 pKa = 4.57GGLNDD2258 pKa = 5.34DD2259 pKa = 4.61LQLTTDD2265 pKa = 3.92EE2266 pKa = 4.39KK2267 pKa = 11.44LLYY2270 pKa = 8.09QTKK2273 pKa = 10.25KK2274 pKa = 10.42VFAKK2278 pKa = 10.72LGLSGNNYY2286 pKa = 10.17DD2287 pKa = 6.05FIWTLQMIANSNFNVCKK2304 pKa = 10.32RR2305 pKa = 11.84LTGRR2309 pKa = 11.84TTGEE2313 pKa = 3.66RR2314 pKa = 11.84LPRR2317 pKa = 11.84SVRR2320 pKa = 11.84SKK2322 pKa = 10.88VIYY2325 pKa = 10.56EE2326 pKa = 3.91MVKK2329 pKa = 10.48LVGEE2333 pKa = 4.12TGMAILQQLAFSQALNYY2350 pKa = 9.57DD2351 pKa = 3.14HH2352 pKa = 7.51RR2353 pKa = 11.84FYY2355 pKa = 11.64AVLAPKK2361 pKa = 10.05AQLGGSRR2368 pKa = 11.84DD2369 pKa = 3.76LLVQEE2374 pKa = 4.72TGTKK2378 pKa = 9.85VIHH2381 pKa = 6.42ATTEE2385 pKa = 3.88MFSRR2389 pKa = 11.84NLLKK2393 pKa = 8.73TTSDD2397 pKa = 3.77DD2398 pKa = 3.79GLTNPHH2404 pKa = 6.39LKK2406 pKa = 8.45EE2407 pKa = 3.79TRR2409 pKa = 11.84LNIGLDD2415 pKa = 3.41MLSTARR2421 pKa = 11.84ALDD2424 pKa = 3.89GKK2426 pKa = 10.01QVSDD2430 pKa = 5.29DD2431 pKa = 4.01SNLLNFFKK2439 pKa = 10.22TVCISGDD2446 pKa = 3.37NTKK2449 pKa = 9.68WGPIHH2454 pKa = 6.69CCSFFSGMMQQLLKK2468 pKa = 10.72DD2469 pKa = 3.79VQDD2472 pKa = 3.04WSSFYY2477 pKa = 11.38KK2478 pKa = 9.99LTFIKK2483 pKa = 10.42NLCRR2487 pKa = 11.84QIEE2490 pKa = 4.17IPAPSIRR2497 pKa = 11.84KK2498 pKa = 8.6ILNVLRR2504 pKa = 11.84FKK2506 pKa = 11.16LSDD2509 pKa = 3.11KK2510 pKa = 11.33GGVEE2514 pKa = 4.06KK2515 pKa = 10.81LSEE2518 pKa = 3.76EE2519 pKa = 4.56AIRR2522 pKa = 11.84SEE2524 pKa = 5.07LINNLAEE2531 pKa = 4.07WEE2533 pKa = 4.44GNDD2536 pKa = 3.46TVKK2539 pKa = 10.71FLITTYY2545 pKa = 10.02ISKK2548 pKa = 11.22GIMAMNSYY2556 pKa = 10.38NHH2558 pKa = 6.32MGQGIHH2564 pKa = 6.64HH2565 pKa = 6.81ATSSLLTSMMAEE2577 pKa = 4.13TFEE2580 pKa = 4.21EE2581 pKa = 4.38LAVDD2585 pKa = 3.49YY2586 pKa = 8.75MKK2588 pKa = 11.02KK2589 pKa = 9.78HH2590 pKa = 5.62FPGLTVNVDD2599 pKa = 3.46HH2600 pKa = 7.19AGSSDD2605 pKa = 4.39DD2606 pKa = 3.63YY2607 pKa = 10.3AKK2609 pKa = 10.74CIIVSGLVSKK2619 pKa = 11.05DD2620 pKa = 2.84MYY2622 pKa = 10.82KK2623 pKa = 10.42RR2624 pKa = 11.84YY2625 pKa = 10.66DD2626 pKa = 3.48GVFWRR2631 pKa = 11.84HH2632 pKa = 4.3MCRR2635 pKa = 11.84LKK2637 pKa = 11.2NFLAAVRR2644 pKa = 11.84RR2645 pKa = 11.84CCQMKK2650 pKa = 10.59DD2651 pKa = 3.12SAKK2654 pKa = 9.95TLVGDD2659 pKa = 4.69CFLEE2663 pKa = 5.16FYY2665 pKa = 11.04SEE2667 pKa = 4.09FMMGNRR2673 pKa = 11.84VTPAVIKK2680 pKa = 9.79FIFTGLINSSVTSPQSLVQACHH2702 pKa = 5.88VSSQQGMYY2710 pKa = 10.74NSVPLVTNAAFTILRR2725 pKa = 11.84QQIFYY2730 pKa = 11.02NHH2732 pKa = 5.9VEE2734 pKa = 4.1DD2735 pKa = 5.47FIRR2738 pKa = 11.84RR2739 pKa = 11.84YY2740 pKa = 10.58GLITLGAVSPFGRR2753 pKa = 11.84LFLPRR2758 pKa = 11.84FSGLVSSSVALEE2770 pKa = 4.1DD2771 pKa = 4.39SEE2773 pKa = 5.04TISKK2777 pKa = 10.14AAAEE2781 pKa = 4.32INSNDD2786 pKa = 2.77IFFNTSSLSNLDD2798 pKa = 3.91KK2799 pKa = 11.34LEE2801 pKa = 3.88QSPDD2805 pKa = 3.23SSGLDD2810 pKa = 3.44DD2811 pKa = 5.45DD2812 pKa = 5.57SVVSTTTVEE2821 pKa = 4.19SSDD2824 pKa = 3.78SKK2826 pKa = 11.13GSSSSFTFDD2835 pKa = 3.16LNRR2838 pKa = 11.84PLSEE2842 pKa = 4.34TEE2844 pKa = 4.15VKK2846 pKa = 10.23FLKK2849 pKa = 10.49LLRR2852 pKa = 11.84EE2853 pKa = 4.31LTSTTACEE2861 pKa = 3.86MLQEE2865 pKa = 5.13KK2866 pKa = 10.6INTLYY2871 pKa = 10.74NDD2873 pKa = 3.5SRR2875 pKa = 11.84EE2876 pKa = 4.34GPLDD2880 pKa = 3.28RR2881 pKa = 11.84HH2882 pKa = 6.76NILQNCRR2889 pKa = 11.84LSEE2892 pKa = 4.22SCDD2895 pKa = 3.0WLLDD2899 pKa = 3.73GKK2901 pKa = 10.92KK2902 pKa = 10.03RR2903 pKa = 11.84GLLEE2907 pKa = 3.56LSRR2910 pKa = 11.84RR2911 pKa = 11.84MSCLLNVLIAGYY2923 pKa = 9.37YY2924 pKa = 9.86RR2925 pKa = 11.84SFGSEE2930 pKa = 3.71GTEE2933 pKa = 3.94KK2934 pKa = 10.19QVKK2937 pKa = 9.95ASWSRR2942 pKa = 11.84DD2943 pKa = 3.41DD2944 pKa = 3.86NRR2946 pKa = 11.84VIEE2949 pKa = 4.91DD2950 pKa = 4.08PMIQLIPEE2958 pKa = 3.98KK2959 pKa = 10.35LRR2961 pKa = 11.84RR2962 pKa = 11.84EE2963 pKa = 4.21LEE2965 pKa = 4.02RR2966 pKa = 11.84LGLSRR2971 pKa = 11.84MEE2973 pKa = 4.22VDD2975 pKa = 3.32EE2976 pKa = 5.07LMPAVGPDD2984 pKa = 3.27EE2985 pKa = 5.12SLSQLVAKK2993 pKa = 10.44KK2994 pKa = 10.44LISLNVSTEE3003 pKa = 4.05EE3004 pKa = 3.87YY3005 pKa = 9.17SAEE3008 pKa = 3.97VSRR3011 pKa = 11.84LKK3013 pKa = 9.53QTLTARR3019 pKa = 11.84NVLHH3023 pKa = 6.57GLAGGIKK3030 pKa = 9.45EE3031 pKa = 4.48LSLPIYY3037 pKa = 9.33TIFMKK3042 pKa = 10.53PYY3044 pKa = 8.52FFKK3047 pKa = 11.3DD3048 pKa = 3.25NVFLDD3053 pKa = 4.65LEE3055 pKa = 4.65DD3056 pKa = 3.72RR3057 pKa = 11.84WSSRR3061 pKa = 11.84HH3062 pKa = 3.74STNYY3066 pKa = 9.73RR3067 pKa = 11.84DD3068 pKa = 3.8STGKK3072 pKa = 8.84MLTGKK3077 pKa = 9.91VVTKK3081 pKa = 8.7FTHH3084 pKa = 5.61WLDD3087 pKa = 3.57TFLSCVVSANRR3098 pKa = 11.84SQEE3101 pKa = 3.74IKK3103 pKa = 10.25EE3104 pKa = 4.11CSLFNPNLRR3113 pKa = 11.84CVNIMVKK3120 pKa = 10.68GNGIKK3125 pKa = 9.61EE3126 pKa = 3.78LSYY3129 pKa = 10.65IRR3131 pKa = 11.84SHH3133 pKa = 7.07LSVLSVEE3140 pKa = 4.55FEE3142 pKa = 4.02NLNLQFSDD3150 pKa = 3.96VNRR3153 pKa = 11.84QKK3155 pKa = 11.31LKK3157 pKa = 10.22IVEE3160 pKa = 4.26SRR3162 pKa = 11.84PPEE3165 pKa = 4.47CEE3167 pKa = 3.85LEE3169 pKa = 4.06ANKK3172 pKa = 10.66AVIIKK3177 pKa = 10.19SKK3179 pKa = 10.39LFSAVEE3185 pKa = 4.02HH3186 pKa = 6.06VRR3188 pKa = 11.84LSNNPAVVMGYY3199 pKa = 10.45LLEE3202 pKa = 4.42EE3203 pKa = 4.29SSISEE3208 pKa = 4.11VKK3210 pKa = 7.98PTKK3213 pKa = 10.42VDD3215 pKa = 4.01FSNLLKK3221 pKa = 10.8HH3222 pKa = 6.33RR3223 pKa = 11.84FKK3225 pKa = 11.3LMQFFPSVFTLLRR3238 pKa = 11.84SLQSEE3243 pKa = 4.39SKK3245 pKa = 10.06EE3246 pKa = 3.94LEE3248 pKa = 4.19KK3249 pKa = 11.07LGEE3252 pKa = 4.45PVDD3255 pKa = 3.48MHH3257 pKa = 6.51QVSKK3261 pKa = 10.8YY3262 pKa = 10.49ANHH3265 pKa = 6.29LTLLCRR3271 pKa = 11.84MIQQSKK3277 pKa = 9.7PSLTVFYY3284 pKa = 9.2MLKK3287 pKa = 9.62GSQMNTEE3294 pKa = 4.1PTVSEE3299 pKa = 4.03LVSYY3303 pKa = 9.43GIKK3306 pKa = 10.05EE3307 pKa = 4.0GRR3309 pKa = 11.84FLKK3312 pKa = 10.69LPEE3315 pKa = 5.45IGLDD3319 pKa = 2.96ASTYY3323 pKa = 8.19SVRR3326 pKa = 11.84YY3327 pKa = 8.49WKK3329 pKa = 10.1ILHH3332 pKa = 6.69CISAIGEE3339 pKa = 4.33LPLSSEE3345 pKa = 4.9DD3346 pKa = 3.52KK3347 pKa = 10.47TSLLISFLNWKK3358 pKa = 7.73VTSDD3362 pKa = 4.71CVDD3365 pKa = 3.43DD3366 pKa = 4.17CCPLEE3371 pKa = 5.53KK3372 pKa = 9.95YY3373 pKa = 10.56DD3374 pKa = 3.82KK3375 pKa = 10.95AIVSEE3380 pKa = 4.51FSGQVLINTLASEE3393 pKa = 4.52LSSVRR3398 pKa = 11.84KK3399 pKa = 9.13DD3400 pKa = 3.35QEE3402 pKa = 4.3RR3403 pKa = 11.84EE3404 pKa = 4.02GLTDD3408 pKa = 5.55LIDD3411 pKa = 4.46YY3412 pKa = 10.42INSPSEE3418 pKa = 3.89LLKK3421 pKa = 10.72KK3422 pKa = 10.37KK3423 pKa = 10.02PYY3425 pKa = 10.63LGTTCRR3431 pKa = 11.84FQCWGEE3437 pKa = 3.95GAKK3440 pKa = 10.17SGKK3443 pKa = 8.17FTYY3446 pKa = 10.13SSRR3449 pKa = 11.84TGEE3452 pKa = 4.16AIGIFVAGKK3461 pKa = 8.88LHH3463 pKa = 6.1IHH3465 pKa = 6.42LTSDD3469 pKa = 3.97SPGLLCEE3476 pKa = 4.3VEE3478 pKa = 4.12RR3479 pKa = 11.84QVLSWLGKK3487 pKa = 9.77RR3488 pKa = 11.84RR3489 pKa = 11.84TDD3491 pKa = 3.19VLTKK3495 pKa = 9.84EE3496 pKa = 3.87QHH3498 pKa = 5.7QFFLDD3503 pKa = 3.77FLPNLSEE3510 pKa = 4.32VVQKK3514 pKa = 11.05NRR3516 pKa = 11.84DD3517 pKa = 3.37GAILGVTIDD3526 pKa = 3.74STNVRR3531 pKa = 11.84MLKK3534 pKa = 9.99YY3535 pKa = 10.49VPPKK3539 pKa = 10.61RR3540 pKa = 11.84NTPVIKK3546 pKa = 9.87IKK3548 pKa = 10.74KK3549 pKa = 9.49QILTVKK3555 pKa = 10.18KK3556 pKa = 8.82QTTLDD3561 pKa = 3.67VEE3563 pKa = 4.44SEE3565 pKa = 3.84PRR3567 pKa = 11.84IVWGHH3572 pKa = 4.92GQLSIVYY3579 pKa = 8.63DD3580 pKa = 3.61EE3581 pKa = 5.65CEE3583 pKa = 4.19TEE3585 pKa = 4.17TTYY3588 pKa = 11.0HH3589 pKa = 6.28EE3590 pKa = 4.2NLIKK3594 pKa = 10.67VKK3596 pKa = 10.6KK3597 pKa = 10.47LVDD3600 pKa = 4.04LASGTTDD3607 pKa = 3.59KK3608 pKa = 11.28LPTAIFSDD3616 pKa = 3.67TRR3618 pKa = 11.84ITLARR3623 pKa = 11.84VKK3625 pKa = 10.61FKK3627 pKa = 10.96TEE3629 pKa = 3.58LLLNSLCLLHH3639 pKa = 7.06CFLKK3643 pKa = 9.49HH3644 pKa = 5.57TSQDD3648 pKa = 3.29AIQEE3652 pKa = 4.3VEE3654 pKa = 4.54SKK3656 pKa = 11.2CNVLEE3661 pKa = 4.31RR3662 pKa = 11.84YY3663 pKa = 9.09LRR3665 pKa = 11.84SGGVQFRR3672 pKa = 11.84PMSEE3676 pKa = 4.03SLDD3679 pKa = 3.59KK3680 pKa = 11.04KK3681 pKa = 8.31VTKK3684 pKa = 10.64LPLQCQSDD3692 pKa = 3.52KK3693 pKa = 11.63DD3694 pKa = 3.67VDD3696 pKa = 3.78KK3697 pKa = 11.14EE3698 pKa = 4.39INFCEE3703 pKa = 4.24DD3704 pKa = 2.97LTRR3707 pKa = 11.84VFSNEE3712 pKa = 3.56NVPLSSWSEE3721 pKa = 3.78VQSYY3725 pKa = 10.26IEE3727 pKa = 4.03EE3728 pKa = 4.22VGFGNVLVHH3737 pKa = 6.54IEE3739 pKa = 4.1KK3740 pKa = 10.86NPTRR3744 pKa = 11.84SDD3746 pKa = 4.06LIWRR3750 pKa = 11.84FSIDD3754 pKa = 3.69SISGNFGPIKK3764 pKa = 10.24DD3765 pKa = 3.25IRR3767 pKa = 11.84TLVTYY3772 pKa = 9.73MSTEE3776 pKa = 4.11TVPKK3780 pKa = 10.23FLLPFLLFEE3789 pKa = 4.57EE3790 pKa = 4.46QLKK3793 pKa = 10.59HH3794 pKa = 6.83LIAGCVEE3801 pKa = 4.52LRR3803 pKa = 11.84DD3804 pKa = 4.09ALNSSGINDD3813 pKa = 3.59RR3814 pKa = 11.84EE3815 pKa = 3.96IAIVALFTCFYY3826 pKa = 8.89YY3827 pKa = 10.85QSDD3830 pKa = 3.88SVKK3833 pKa = 10.51RR3834 pKa = 11.84QGPVCSISSFCSLIGDD3850 pKa = 4.65DD3851 pKa = 6.28LLPLDD3856 pKa = 4.42NRR3858 pKa = 11.84LQARR3862 pKa = 11.84VLPEE3866 pKa = 3.53QDD3868 pKa = 2.98NVKK3871 pKa = 10.49LHH3873 pKa = 6.48FKK3875 pKa = 11.06LNLTTDD3881 pKa = 3.24SALGKK3886 pKa = 9.67KK3887 pKa = 10.12DD3888 pKa = 3.68KK3889 pKa = 10.93AIQAKK3894 pKa = 10.09KK3895 pKa = 10.03IISRR3899 pKa = 11.84YY3900 pKa = 8.99LRR3902 pKa = 11.84LIFTEE3907 pKa = 4.93DD3908 pKa = 3.66DD3909 pKa = 3.35MDD3911 pKa = 4.57LKK3913 pKa = 10.75RR3914 pKa = 11.84LKK3916 pKa = 10.68SDD3918 pKa = 3.01ATKK3921 pKa = 10.98VKK3923 pKa = 10.49LSSEE3927 pKa = 4.25KK3928 pKa = 10.04EE3929 pKa = 4.08CEE3931 pKa = 3.8FLEE3934 pKa = 4.84FCLHH3938 pKa = 6.73SDD3940 pKa = 3.97LSYY3943 pKa = 10.94ALNYY3947 pKa = 9.96RR3948 pKa = 11.84VLLEE3952 pKa = 4.12HH3953 pKa = 7.28LIDD3956 pKa = 5.14LEE3958 pKa = 4.51DD3959 pKa = 3.78RR3960 pKa = 11.84AKK3962 pKa = 9.74KK3963 pKa = 7.08TACVLIEE3970 pKa = 4.28EE3971 pKa = 5.38FILMLTGRR3979 pKa = 11.84LMISSTIDD3987 pKa = 3.13SDD3989 pKa = 4.3SKK3991 pKa = 10.7RR3992 pKa = 11.84TLEE3995 pKa = 5.33DD3996 pKa = 3.8DD3997 pKa = 4.0ALCLEE4002 pKa = 5.18DD4003 pKa = 6.45LLDD4006 pKa = 4.3SDD4008 pKa = 5.55NEE4010 pKa = 4.15ASSSKK4015 pKa = 10.71SDD4017 pKa = 3.59NEE4019 pKa = 3.93EE4020 pKa = 3.76QIALQTGKK4028 pKa = 10.74FNFNWDD4034 pKa = 2.97SDD4036 pKa = 3.71

Molecular weight:
459.39 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>sp|Q66431|L_DUGBA RNA-directed RNA polymerase L OS=Dugbe virus (isolate ArD44313) OX=766194 GN=L PE=1 SV=1
MM1 pKa = 7.64SKK3 pKa = 10.21RR4 pKa = 11.84VLIIAVVVYY13 pKa = 9.49LVFTTQNQITGNHH26 pKa = 4.37TTINSSSPSTTEE38 pKa = 3.57ASSTPTVSRR47 pKa = 11.84TPQTTTTSTAVSTTITATTTPTASWTTQSQYY78 pKa = 11.03FNKK81 pKa = 8.0TTQHH85 pKa = 5.15HH86 pKa = 4.95WRR88 pKa = 11.84EE89 pKa = 3.69EE90 pKa = 4.14TMISRR95 pKa = 11.84NPTVLDD101 pKa = 3.63RR102 pKa = 11.84QSRR105 pKa = 11.84ASSVRR110 pKa = 11.84EE111 pKa = 3.67LLNTKK116 pKa = 10.08FLMLLGFIPKK126 pKa = 10.46GEE128 pKa = 4.17VNHH131 pKa = 7.07LEE133 pKa = 4.05NACNRR138 pKa = 11.84EE139 pKa = 3.82GKK141 pKa = 9.82NCTEE145 pKa = 5.24LILKK149 pKa = 9.33EE150 pKa = 3.94RR151 pKa = 11.84IARR154 pKa = 11.84FFSEE158 pKa = 4.56TEE160 pKa = 3.93KK161 pKa = 10.55EE162 pKa = 4.3SCYY165 pKa = 9.74NTYY168 pKa = 10.62LEE170 pKa = 3.94KK171 pKa = 10.5HH172 pKa = 5.97LRR174 pKa = 11.84SVSPEE179 pKa = 3.76VSLTPYY185 pKa = 9.96RR186 pKa = 11.84VLGLRR191 pKa = 11.84EE192 pKa = 4.83DD193 pKa = 3.72ILLKK197 pKa = 10.72EE198 pKa = 3.8IDD200 pKa = 3.21RR201 pKa = 11.84RR202 pKa = 11.84IIRR205 pKa = 11.84FEE207 pKa = 3.84TDD209 pKa = 2.93SQRR212 pKa = 11.84VTCLSASLLKK222 pKa = 10.07PDD224 pKa = 3.35VFIRR228 pKa = 11.84EE229 pKa = 3.83QRR231 pKa = 11.84IDD233 pKa = 3.61AKK235 pKa = 10.52PSNGPKK241 pKa = 9.59IVPVDD246 pKa = 3.93SVACMNLEE254 pKa = 4.04ANVDD258 pKa = 3.45VRR260 pKa = 11.84SNKK263 pKa = 9.94LVIQSLMTTVKK274 pKa = 10.46ISLKK278 pKa = 8.62NCKK281 pKa = 9.78VVVNSRR287 pKa = 11.84QCIHH291 pKa = 5.77QQTGSGVIKK300 pKa = 10.35VPKK303 pKa = 10.05FEE305 pKa = 4.12KK306 pKa = 10.02QQGGTWSSYY315 pKa = 9.33IAGVYY320 pKa = 7.65TATIDD325 pKa = 5.19LLDD328 pKa = 4.88EE329 pKa = 4.73NNQNCKK335 pKa = 10.39LFTEE339 pKa = 5.29CIVKK343 pKa = 10.06GRR345 pKa = 11.84EE346 pKa = 3.93LVKK349 pKa = 10.78GQSEE353 pKa = 4.17LKK355 pKa = 10.4SFNIEE360 pKa = 3.76VLLPRR365 pKa = 11.84VMKK368 pKa = 9.84TRR370 pKa = 11.84RR371 pKa = 11.84KK372 pKa = 9.81LLAVTDD378 pKa = 4.94GSTEE382 pKa = 4.29CNSGTQLIEE391 pKa = 4.18GKK393 pKa = 10.3SIEE396 pKa = 4.16VHH398 pKa = 5.76KK399 pKa = 10.79QDD401 pKa = 4.36IGGPGKK407 pKa = 10.62KK408 pKa = 8.67LTICNGTSVLDD419 pKa = 3.69VPLDD423 pKa = 3.96EE424 pKa = 5.43GHH426 pKa = 6.6GCYY429 pKa = 9.58TINVITSKK437 pKa = 10.42RR438 pKa = 11.84ACRR441 pKa = 11.84PKK443 pKa = 10.54NSKK446 pKa = 9.26LQCSIDD452 pKa = 4.39KK453 pKa = 10.03EE454 pKa = 4.4LKK456 pKa = 9.29PCDD459 pKa = 3.55SGKK462 pKa = 10.37CLSISQKK469 pKa = 10.3GAGHH473 pKa = 6.46IKK475 pKa = 9.72VSRR478 pKa = 11.84GKK480 pKa = 9.06TILITEE486 pKa = 4.54CKK488 pKa = 8.9EE489 pKa = 3.69HH490 pKa = 6.46CQIPVPTGKK499 pKa = 10.66GDD501 pKa = 3.55IMVDD505 pKa = 3.52CSGGRR510 pKa = 11.84QHH512 pKa = 6.43YY513 pKa = 10.72LEE515 pKa = 4.34VNIVDD520 pKa = 3.24IHH522 pKa = 6.59CPNTKK527 pKa = 10.0FLGGIMLYY535 pKa = 9.46FCRR538 pKa = 11.84MSSRR542 pKa = 11.84PTVALLLGIWIGCGYY557 pKa = 10.35ILTCIFSFLLYY568 pKa = 10.58HH569 pKa = 7.31LILFFANCIKK579 pKa = 10.3QCRR582 pKa = 11.84KK583 pKa = 9.25KK584 pKa = 10.92GEE586 pKa = 4.16RR587 pKa = 11.84LGEE590 pKa = 3.86ICVKK594 pKa = 10.76CEE596 pKa = 3.77QQTVNLMDD604 pKa = 4.65QEE606 pKa = 4.43LHH608 pKa = 7.41DD609 pKa = 5.11LNCNFNLCPYY619 pKa = 8.77CCNRR623 pKa = 11.84MSDD626 pKa = 3.65EE627 pKa = 4.06GMSRR631 pKa = 11.84HH632 pKa = 6.06VGKK635 pKa = 10.52CPKK638 pKa = 10.07RR639 pKa = 11.84LEE641 pKa = 4.08RR642 pKa = 11.84LNEE645 pKa = 3.61IEE647 pKa = 5.55LYY649 pKa = 9.42LTTSEE654 pKa = 4.43CLCLSVCYY662 pKa = 9.94QLLISVGIFLKK673 pKa = 9.76RR674 pKa = 11.84TTWLVVLLVLLGLAISPVQGAPTEE698 pKa = 4.15VSNVKK703 pKa = 10.09QDD705 pKa = 3.06GDD707 pKa = 3.62YY708 pKa = 10.64SICYY712 pKa = 9.9FIFGCLVTAALLLKK726 pKa = 10.4VKK728 pKa = 9.37RR729 pKa = 11.84TNSNGIVVVVDD740 pKa = 3.06SFGRR744 pKa = 11.84CPYY747 pKa = 10.47CNEE750 pKa = 3.83FTDD753 pKa = 4.08SLFEE757 pKa = 4.11EE758 pKa = 4.81VLHH761 pKa = 6.83DD762 pKa = 4.2TLCSLCVCPFCEE774 pKa = 4.59KK775 pKa = 10.36QALDD779 pKa = 3.62LVTLEE784 pKa = 4.2EE785 pKa = 4.47HH786 pKa = 6.83VKK788 pKa = 10.22EE789 pKa = 4.43CYY791 pKa = 9.7KK792 pKa = 10.56VATRR796 pKa = 11.84KK797 pKa = 10.5DD798 pKa = 2.9IFKK801 pKa = 10.5ILGRR805 pKa = 11.84KK806 pKa = 6.64FTNALVRR813 pKa = 11.84RR814 pKa = 11.84EE815 pKa = 3.94KK816 pKa = 11.17LFTTGLQLFINKK828 pKa = 8.55TNVVVFALIMCFLLLLTGHH847 pKa = 6.56NASAFDD853 pKa = 4.99SGDD856 pKa = 3.46LPDD859 pKa = 4.85GVWEE863 pKa = 4.35EE864 pKa = 4.06SSQLVKK870 pKa = 10.79SCTQFCYY877 pKa = 10.12IEE879 pKa = 5.02EE880 pKa = 4.25DD881 pKa = 3.54VCYY884 pKa = 10.37CPAEE888 pKa = 4.61DD889 pKa = 4.01GVGRR893 pKa = 11.84KK894 pKa = 9.03LLFFNGLQNSVKK906 pKa = 10.34RR907 pKa = 11.84LSDD910 pKa = 3.25SHH912 pKa = 7.65KK913 pKa = 10.58LLTSVSIDD921 pKa = 3.72APWGRR926 pKa = 11.84INVEE930 pKa = 4.41STWKK934 pKa = 8.39PTLAASNIAMSWSSTDD950 pKa = 2.94IKK952 pKa = 10.85GEE954 pKa = 3.87KK955 pKa = 9.99VILSGRR961 pKa = 11.84STSIIKK967 pKa = 10.46LKK969 pKa = 10.68EE970 pKa = 3.69KK971 pKa = 10.04TGVMWKK977 pKa = 10.46LVGSGLASEE986 pKa = 4.41KK987 pKa = 10.37KK988 pKa = 10.01KK989 pKa = 10.47PFRR992 pKa = 11.84FPIMDD997 pKa = 4.26FAQVYY1002 pKa = 10.32NSVFQYY1008 pKa = 9.25ITGDD1012 pKa = 3.36RR1013 pKa = 11.84LLSEE1017 pKa = 4.16WPKK1020 pKa = 10.84AVCTGDD1026 pKa = 3.4CPHH1029 pKa = 7.37RR1030 pKa = 11.84CGCQTSTCMAKK1041 pKa = 9.81EE1042 pKa = 4.17CHH1044 pKa = 5.39TQEE1047 pKa = 4.37CVSTHH1052 pKa = 4.71MVLGIGTGCTCCGMDD1067 pKa = 4.51VEE1069 pKa = 5.6RR1070 pKa = 11.84PFNKK1074 pKa = 10.2YY1075 pKa = 10.56LGVKK1079 pKa = 9.26WSTEE1083 pKa = 3.78YY1084 pKa = 11.04LRR1086 pKa = 11.84TEE1088 pKa = 3.87VLVCVEE1094 pKa = 3.9VTEE1097 pKa = 4.48EE1098 pKa = 3.96EE1099 pKa = 4.31RR1100 pKa = 11.84HH1101 pKa = 5.56CEE1103 pKa = 3.52IVEE1106 pKa = 3.84AGTRR1110 pKa = 11.84FNIGPITITISDD1122 pKa = 3.97PQNIGSKK1129 pKa = 10.38LPEE1132 pKa = 4.08SLMTVQEE1139 pKa = 4.08IDD1141 pKa = 3.46DD1142 pKa = 4.43SNFVDD1147 pKa = 3.69IMHH1150 pKa = 6.65VGNVISADD1158 pKa = 3.48NSCRR1162 pKa = 11.84LQSCTHH1168 pKa = 6.36GSAVTTRR1175 pKa = 11.84FTALTALIKK1184 pKa = 10.27DD1185 pKa = 3.9DD1186 pKa = 4.39HH1187 pKa = 7.67SSGLNLAVLDD1197 pKa = 4.28PKK1199 pKa = 11.3VNSSWLSWEE1208 pKa = 4.28GCDD1211 pKa = 3.83MDD1213 pKa = 4.8YY1214 pKa = 10.83YY1215 pKa = 11.18CNVGDD1220 pKa = 4.96WPTCTYY1226 pKa = 10.13TGVVTQKK1233 pKa = 10.51LRR1235 pKa = 11.84EE1236 pKa = 3.95FLKK1239 pKa = 10.73LDD1241 pKa = 3.2QHH1243 pKa = 7.01RR1244 pKa = 11.84KK1245 pKa = 9.23RR1246 pKa = 11.84LHH1248 pKa = 4.95TTLSFSLKK1256 pKa = 10.22KK1257 pKa = 10.19NLSKK1261 pKa = 10.74RR1262 pKa = 11.84SHH1264 pKa = 5.44TSVRR1268 pKa = 11.84LEE1270 pKa = 4.11GKK1272 pKa = 7.69TVTRR1276 pKa = 11.84MEE1278 pKa = 4.42VKK1280 pKa = 8.76VTALIEE1286 pKa = 4.0VDD1288 pKa = 3.67GMEE1291 pKa = 4.49LHH1293 pKa = 6.86SKK1295 pKa = 8.76TIRR1298 pKa = 11.84LSGIRR1303 pKa = 11.84LTGLKK1308 pKa = 10.46CSGCFSCTSGISCSVNAKK1326 pKa = 8.49LTSPDD1331 pKa = 3.49EE1332 pKa = 4.34FTLHH1336 pKa = 6.42LRR1338 pKa = 11.84STSPNVVVAEE1348 pKa = 3.93TSIIARR1354 pKa = 11.84KK1355 pKa = 9.59GPSATTSRR1363 pKa = 11.84FKK1365 pKa = 11.11VFSVRR1370 pKa = 11.84DD1371 pKa = 3.55TKK1373 pKa = 10.85KK1374 pKa = 8.88ICFEE1378 pKa = 4.0VVEE1381 pKa = 4.35RR1382 pKa = 11.84EE1383 pKa = 4.09YY1384 pKa = 11.45CKK1386 pKa = 10.94DD1387 pKa = 3.57CTPDD1391 pKa = 3.38EE1392 pKa = 4.45LTTCTGVEE1400 pKa = 4.17LEE1402 pKa = 4.16PTKK1405 pKa = 10.79DD1406 pKa = 2.69ILLEE1410 pKa = 3.9HH1411 pKa = 7.15RR1412 pKa = 11.84GTIVQHH1418 pKa = 6.46QNDD1421 pKa = 4.05TCKK1424 pKa = 10.95SKK1426 pKa = 10.5IDD1428 pKa = 3.51CWSNSISSFASGIGDD1443 pKa = 4.08FFKK1446 pKa = 10.65HH1447 pKa = 5.88YY1448 pKa = 9.61IGSIAVGVLGTVLPFALLILFFIYY1472 pKa = 9.93GDD1474 pKa = 3.36KK1475 pKa = 10.39MLWPFKK1481 pKa = 10.38VFCRR1485 pKa = 11.84PCRR1488 pKa = 11.84RR1489 pKa = 11.84CCRR1492 pKa = 11.84KK1493 pKa = 10.12NEE1495 pKa = 4.24GYY1497 pKa = 10.81NKK1499 pKa = 10.06LAEE1502 pKa = 4.22EE1503 pKa = 4.38EE1504 pKa = 4.11EE1505 pKa = 4.08LRR1507 pKa = 11.84DD1508 pKa = 4.22IIRR1511 pKa = 11.84KK1512 pKa = 8.82FSKK1515 pKa = 10.45SGEE1518 pKa = 4.39LINKK1522 pKa = 7.64DD1523 pKa = 3.38AKK1525 pKa = 10.74DD1526 pKa = 3.4KK1527 pKa = 10.22RR1528 pKa = 11.84TLARR1532 pKa = 11.84LFMSDD1537 pKa = 3.08NPKK1540 pKa = 10.41LKK1542 pKa = 10.34KK1543 pKa = 9.68EE1544 pKa = 4.16KK1545 pKa = 10.13KK1546 pKa = 9.74LSEE1549 pKa = 4.01IAA1551 pKa = 3.8

Molecular weight:
173.35 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

3

0

3

6070

483

4036

2023.3

228.89

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

4.267 ± 0.764

2.965 ± 1.005

5.47 ± 0.534

7.117 ± 0.485

3.987 ± 0.075

5.239 ± 0.552

1.911 ± 0.138

5.865 ± 0.275

7.809 ± 0.279

11.301 ± 0.833

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.109 ± 0.205

4.712 ± 0.239

3.147 ± 0.214

3.46 ± 0.248

5.206 ± 0.257

8.863 ± 0.493

6.359 ± 0.905

6.557 ± 0.555

1.087 ± 0.223

2.57 ± 0.281

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski