Amino acid dipepetide frequency for Botrytis porri

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.175AlaAla: 7.175 ± 0.046	0.927AlaCys: 0.927 ± 0.014	3.609AlaAsp: 3.609 ± 0.028	4.793AlaGlu: 4.793 ± 0.038	2.826AlaPhe: 2.826 ± 0.025	5.084AlaGly: 5.084 ± 0.041	1.538AlaHis: 1.538 ± 0.018	4.299AlaIle: 4.299 ± 0.031	4.203AlaLys: 4.203 ± 0.033	6.729AlaLeu: 6.729 ± 0.046	1.847AlaMet: 1.847 ± 0.018	3.021AlaAsn: 3.021 ± 0.026	4.297AlaPro: 4.297 ± 0.032	3.069AlaGln: 3.069 ± 0.028	4.161AlaArg: 4.161 ± 0.033	6.835AlaSer: 6.835 ± 0.044	4.95AlaThr: 4.95 ± 0.036	4.443AlaVal: 4.443 ± 0.031	0.976AlaTrp: 0.976 ± 0.013	2.007AlaTyr: 2.007 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	0.846CysAla: 0.846 ± 0.014	0.23CysCys: 0.23 ± 0.008	0.631CysAsp: 0.631 ± 0.012	0.627CysGlu: 0.627 ± 0.011	0.498CysPhe: 0.498 ± 0.01	0.925CysGly: 0.925 ± 0.016	0.293CysHis: 0.293 ± 0.008	0.7CysIle: 0.7 ± 0.014	0.562CysLys: 0.562 ± 0.013	1.134CysLeu: 1.134 ± 0.016	0.272CysMet: 0.272 ± 0.008	0.455CysAsn: 0.455 ± 0.01	0.624CysPro: 0.624 ± 0.013	0.411CysGln: 0.411 ± 0.008	0.636CysArg: 0.636 ± 0.014	0.898CysSer: 0.898 ± 0.014	0.692CysThr: 0.692 ± 0.012	0.721CysVal: 0.721 ± 0.012	0.181CysTrp: 0.181 ± 0.006	0.347CysTyr: 0.347 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.07AspAla: 4.07 ± 0.033	0.632AspCys: 0.632 ± 0.012	4.152AspAsp: 4.152 ± 0.043	4.696AspGlu: 4.696 ± 0.042	2.23AspPhe: 2.23 ± 0.024	3.861AspGly: 3.861 ± 0.03	1.177AspHis: 1.177 ± 0.018	3.327AspIle: 3.327 ± 0.026	2.438AspLys: 2.438 ± 0.026	4.908AspLeu: 4.908 ± 0.038	1.283AspMet: 1.283 ± 0.017	2.1AspAsn: 2.1 ± 0.022	2.953AspPro: 2.953 ± 0.026	1.78AspGln: 1.78 ± 0.023	2.795AspArg: 2.795 ± 0.031	4.374AspSer: 4.374 ± 0.033	2.971AspThr: 2.971 ± 0.025	3.392AspVal: 3.392 ± 0.027	0.83AspTrp: 0.83 ± 0.015	1.606AspTyr: 1.606 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	4.962GluAla: 4.962 ± 0.038	0.616GluCys: 0.616 ± 0.012	4.488GluAsp: 4.488 ± 0.038	6.422GluGlu: 6.422 ± 0.071	2.106GluPhe: 2.106 ± 0.02	4.042GluGly: 4.042 ± 0.035	1.326GluHis: 1.326 ± 0.018	3.754GluIle: 3.754 ± 0.028	4.563GluLys: 4.563 ± 0.045	5.182GluLeu: 5.182 ± 0.038	1.686GluMet: 1.686 ± 0.02	2.938GluAsn: 2.938 ± 0.024	2.619GluPro: 2.619 ± 0.033	2.383GluGln: 2.383 ± 0.026	4.165GluArg: 4.165 ± 0.047	4.825GluSer: 4.825 ± 0.04	3.548GluThr: 3.548 ± 0.027	3.791GluVal: 3.791 ± 0.027	0.915GluTrp: 0.915 ± 0.015	1.788GluTyr: 1.788 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	2.817PheAla: 2.817 ± 0.026	0.539PheCys: 0.539 ± 0.01	2.239PheAsp: 2.239 ± 0.02	2.342PheGlu: 2.342 ± 0.02	1.53PhePhe: 1.53 ± 0.02	2.85PheGly: 2.85 ± 0.031	0.879PheHis: 0.879 ± 0.014	1.903PheIle: 1.903 ± 0.02	1.7PheLys: 1.7 ± 0.02	3.355PheLeu: 3.355 ± 0.026	0.834PheMet: 0.834 ± 0.014	1.588PheAsn: 1.588 ± 0.019	1.938PhePro: 1.938 ± 0.023	1.403PheGln: 1.403 ± 0.016	1.824PheArg: 1.824 ± 0.018	3.103PheSer: 3.103 ± 0.024	2.243PheThr: 2.243 ± 0.02	2.258PheVal: 2.258 ± 0.025	0.616PheTrp: 0.616 ± 0.011	1.098PheTyr: 1.098 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	4.668GlyAla: 4.668 ± 0.038	0.825GlyCys: 0.825 ± 0.014	3.507GlyAsp: 3.507 ± 0.027	3.956GlyGlu: 3.956 ± 0.032	2.761GlyPhe: 2.761 ± 0.027	5.807GlyGly: 5.807 ± 0.057	1.535GlyHis: 1.535 ± 0.02	3.751GlyIle: 3.751 ± 0.03	3.923GlyLys: 3.923 ± 0.035	5.698GlyLeu: 5.698 ± 0.038	1.717GlyMet: 1.717 ± 0.017	2.994GlyAsn: 2.994 ± 0.031	2.937GlyPro: 2.937 ± 0.028	2.245GlyGln: 2.245 ± 0.023	3.82GlyArg: 3.82 ± 0.036	5.755GlySer: 5.755 ± 0.032	3.976GlyThr: 3.976 ± 0.032	4.176GlyVal: 4.176 ± 0.029	1.088GlyTrp: 1.088 ± 0.017	2.151GlyTyr: 2.151 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	1.57HisAla: 1.57 ± 0.018	0.301HisCys: 0.301 ± 0.008	1.27HisAsp: 1.27 ± 0.017	1.359HisGlu: 1.359 ± 0.018	0.88HisPhe: 0.88 ± 0.012	1.572HisGly: 1.572 ± 0.022	0.79HisHis: 0.79 ± 0.015	1.246HisIle: 1.246 ± 0.014	1.016HisLys: 1.016 ± 0.014	2.029HisLeu: 2.029 ± 0.02	0.48HisMet: 0.48 ± 0.009	0.953HisAsn: 0.953 ± 0.013	1.522HisPro: 1.522 ± 0.018	0.976HisGln: 0.976 ± 0.016	1.364HisArg: 1.364 ± 0.017	1.926HisSer: 1.926 ± 0.027	1.334HisThr: 1.334 ± 0.017	1.258HisVal: 1.258 ± 0.017	0.3HisTrp: 0.3 ± 0.007	0.691HisTyr: 0.691 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.297IleAla: 4.297 ± 0.033	0.775IleCys: 0.775 ± 0.013	3.169IleAsp: 3.169 ± 0.027	3.478IleGlu: 3.478 ± 0.031	2.177IlePhe: 2.177 ± 0.022	3.432IleGly: 3.432 ± 0.031	1.301IleHis: 1.301 ± 0.018	2.983IleIle: 2.983 ± 0.028	2.711IleLys: 2.711 ± 0.025	4.949IleLeu: 4.949 ± 0.039	1.144IleMet: 1.144 ± 0.016	2.206IleAsn: 2.206 ± 0.019	3.495IlePro: 3.495 ± 0.03	2.082IleGln: 2.082 ± 0.02	2.822IleArg: 2.822 ± 0.022	4.743IleSer: 4.743 ± 0.034	3.304IleThr: 3.304 ± 0.032	3.332IleVal: 3.332 ± 0.029	0.769IleTrp: 0.769 ± 0.013	1.595IleTyr: 1.595 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.33LysAla: 4.33 ± 0.038	0.573LysCys: 0.573 ± 0.012	3.11LysAsp: 3.11 ± 0.03	4.166LysGlu: 4.166 ± 0.043	1.755LysPhe: 1.755 ± 0.019	3.333LysGly: 3.333 ± 0.026	1.189LysHis: 1.189 ± 0.016	2.962LysIle: 2.962 ± 0.027	4.148LysLys: 4.148 ± 0.049	4.441LysLeu: 4.441 ± 0.032	1.209LysMet: 1.209 ± 0.014	2.282LysAsn: 2.282 ± 0.022	2.835LysPro: 2.835 ± 0.026	1.905LysGln: 1.905 ± 0.02	3.648LysArg: 3.648 ± 0.03	4.445LysSer: 4.445 ± 0.037	3.148LysThr: 3.148 ± 0.027	3.152LysVal: 3.152 ± 0.025	0.758LysTrp: 0.758 ± 0.011	1.535LysTyr: 1.535 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	6.801LeuAla: 6.801 ± 0.042	1.092LeuCys: 1.092 ± 0.016	4.794LeuAsp: 4.794 ± 0.036	5.61LeuGlu: 5.61 ± 0.041	3.153LeuPhe: 3.153 ± 0.027	5.551LeuGly: 5.551 ± 0.038	2.031LeuHis: 2.031 ± 0.017	4.178LeuIle: 4.178 ± 0.031	4.64LeuLys: 4.64 ± 0.037	7.63LeuLeu: 7.63 ± 0.054	1.766LeuMet: 1.766 ± 0.02	3.477LeuAsn: 3.477 ± 0.026	5.262LeuPro: 5.262 ± 0.034	3.627LeuGln: 3.627 ± 0.03	5.132LeuArg: 5.132 ± 0.036	7.278LeuSer: 7.278 ± 0.044	4.75LeuThr: 4.75 ± 0.034	4.785LeuVal: 4.785 ± 0.036	1.083LeuTrp: 1.083 ± 0.016	2.264LeuTyr: 2.264 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	2.071MetAla: 2.071 ± 0.017	0.24MetCys: 0.24 ± 0.007	1.323MetAsp: 1.323 ± 0.017	1.498MetGlu: 1.498 ± 0.02	0.771MetPhe: 0.771 ± 0.013	1.59MetGly: 1.59 ± 0.017	0.462MetHis: 0.462 ± 0.009	1.163MetIle: 1.163 ± 0.016	1.24MetLys: 1.24 ± 0.016	1.706MetLeu: 1.706 ± 0.017	0.626MetMet: 0.626 ± 0.011	0.991MetAsn: 0.991 ± 0.014	1.224MetPro: 1.224 ± 0.018	0.855MetGln: 0.855 ± 0.014	1.242MetArg: 1.242 ± 0.017	2.046MetSer: 2.046 ± 0.021	1.305MetThr: 1.305 ± 0.017	1.303MetVal: 1.303 ± 0.016	0.253MetTrp: 0.253 ± 0.007	0.539MetTyr: 0.539 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.235AsnAla: 3.235 ± 0.026	0.487AsnCys: 0.487 ± 0.009	2.262AsnAsp: 2.262 ± 0.023	2.511AsnGlu: 2.511 ± 0.023	1.665AsnPhe: 1.665 ± 0.019	3.424AsnGly: 3.424 ± 0.031	1.046AsnHis: 1.046 ± 0.016	2.504AsnIle: 2.504 ± 0.022	1.93AsnLys: 1.93 ± 0.019	3.641AsnLeu: 3.641 ± 0.023	0.968AsnMet: 0.968 ± 0.014	1.961AsnAsn: 1.961 ± 0.026	2.671AsnPro: 2.671 ± 0.023	1.554AsnGln: 1.554 ± 0.016	2.116AsnArg: 2.116 ± 0.023	3.618AsnSer: 3.618 ± 0.031	2.728AsnThr: 2.728 ± 0.025	2.464AsnVal: 2.464 ± 0.023	0.582AsnTrp: 0.582 ± 0.01	1.255AsnTyr: 1.255 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	4.385ProAla: 4.385 ± 0.039	0.457ProCys: 0.457 ± 0.009	2.754ProAsp: 2.754 ± 0.025	3.637ProGlu: 3.637 ± 0.034	1.959ProPhe: 1.959 ± 0.02	3.446ProGly: 3.446 ± 0.028	1.268ProHis: 1.268 ± 0.017	3.055ProIle: 3.055 ± 0.026	2.959ProLys: 2.959 ± 0.026	4.555ProLeu: 4.555 ± 0.032	1.065ProMet: 1.065 ± 0.017	2.455ProAsn: 2.455 ± 0.026	4.741ProPro: 4.741 ± 0.067	2.463ProGln: 2.463 ± 0.032	3.182ProArg: 3.182 ± 0.034	6.147ProSer: 6.147 ± 0.05	4.127ProThr: 4.127 ± 0.032	3.212ProVal: 3.212 ± 0.029	0.63ProTrp: 0.63 ± 0.012	1.503ProTyr: 1.503 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	3.074GlnAla: 3.074 ± 0.03	0.414GlnCys: 0.414 ± 0.01	1.976GlnAsp: 1.976 ± 0.023	2.431GlnGlu: 2.431 ± 0.025	1.296GlnPhe: 1.296 ± 0.017	2.191GlnGly: 2.191 ± 0.023	0.988GlnHis: 0.988 ± 0.018	2.116GlnIle: 2.116 ± 0.022	2.265GlnLys: 2.265 ± 0.022	3.137GlnLeu: 3.137 ± 0.027	0.905GlnMet: 0.905 ± 0.014	1.874GlnAsn: 1.874 ± 0.025	2.209GlnPro: 2.209 ± 0.027	2.256GlnGln: 2.256 ± 0.042	2.382GlnArg: 2.382 ± 0.025	3.313GlnSer: 3.313 ± 0.031	2.33GlnThr: 2.33 ± 0.021	2.017GlnVal: 2.017 ± 0.018	0.515GlnTrp: 0.515 ± 0.01	1.216GlnTyr: 1.216 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	3.979ArgAla: 3.979 ± 0.034	0.618ArgCys: 0.618 ± 0.011	3.16ArgAsp: 3.16 ± 0.033	4.031ArgGlu: 4.031 ± 0.04	1.94ArgPhe: 1.94 ± 0.019	3.688ArgGly: 3.688 ± 0.034	1.327ArgHis: 1.327 ± 0.018	2.979ArgIle: 2.979 ± 0.026	3.782ArgLys: 3.782 ± 0.033	4.702ArgLeu: 4.702 ± 0.033	1.29ArgMet: 1.29 ± 0.017	2.568ArgAsn: 2.568 ± 0.024	3.02ArgPro: 3.02 ± 0.03	2.345ArgGln: 2.345 ± 0.022	4.549ArgArg: 4.549 ± 0.048	4.731ArgSer: 4.731 ± 0.045	3.084ArgThr: 3.084 ± 0.027	2.995ArgVal: 2.995 ± 0.027	0.798ArgTrp: 0.798 ± 0.015	1.553ArgTyr: 1.553 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	6.32SerAla: 6.32 ± 0.044	0.886SerCys: 0.886 ± 0.015	4.368SerAsp: 4.368 ± 0.039	4.667SerGlu: 4.667 ± 0.039	3.162SerPhe: 3.162 ± 0.028	5.593SerGly: 5.593 ± 0.038	2.065SerHis: 2.065 ± 0.021	4.883SerIle: 4.883 ± 0.035	4.526SerLys: 4.526 ± 0.032	7.18SerLeu: 7.18 ± 0.045	1.842SerMet: 1.842 ± 0.02	3.914SerAsn: 3.914 ± 0.035	5.8SerPro: 5.8 ± 0.053	3.51SerGln: 3.51 ± 0.031	4.98SerArg: 4.98 ± 0.045	10.211SerSer: 10.211 ± 0.101	6.525SerThr: 6.525 ± 0.059	4.516SerVal: 4.516 ± 0.032	1.037SerTrp: 1.037 ± 0.016	2.25SerTyr: 2.25 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	4.702ThrAla: 4.702 ± 0.03	0.744ThrCys: 0.744 ± 0.013	2.781ThrAsp: 2.781 ± 0.024	3.24ThrGlu: 3.24 ± 0.029	2.386ThrPhe: 2.386 ± 0.022	4.078ThrGly: 4.078 ± 0.034	1.338ThrHis: 1.338 ± 0.016	3.654ThrIle: 3.654 ± 0.029	3.036ThrLys: 3.036 ± 0.026	5.212ThrLeu: 5.212 ± 0.03	1.22ThrMet: 1.22 ± 0.017	2.586ThrAsn: 2.586 ± 0.02	4.592ThrPro: 4.592 ± 0.042	2.215ThrGln: 2.215 ± 0.023	3.009ThrArg: 3.009 ± 0.026	6.319ThrSer: 6.319 ± 0.059	4.737ThrThr: 4.737 ± 0.044	3.367ThrVal: 3.367 ± 0.03	0.79ThrTrp: 0.79 ± 0.014	1.684ThrTyr: 1.684 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	4.551ValAla: 4.551 ± 0.032	0.712ValCys: 0.712 ± 0.012	3.467ValAsp: 3.467 ± 0.03	4.083ValGlu: 4.083 ± 0.035	2.253ValPhe: 2.253 ± 0.023	3.831ValGly: 3.831 ± 0.032	1.235ValHis: 1.235 ± 0.014	3.0ValIle: 3.0 ± 0.025	3.142ValLys: 3.142 ± 0.03	5.004ValLeu: 5.004 ± 0.032	1.317ValMet: 1.317 ± 0.014	2.292ValAsn: 2.292 ± 0.023	3.233ValPro: 3.233 ± 0.025	2.169ValGln: 2.169 ± 0.021	2.975ValArg: 2.975 ± 0.021	4.483ValSer: 4.483 ± 0.033	3.343ValThr: 3.343 ± 0.029	3.903ValVal: 3.903 ± 0.033	0.777ValTrp: 0.777 ± 0.011	1.622ValTyr: 1.622 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	0.952TrpAla: 0.952 ± 0.014	0.187TrpCys: 0.187 ± 0.006	0.835TrpAsp: 0.835 ± 0.013	0.888TrpGlu: 0.888 ± 0.013	0.505TrpPhe: 0.505 ± 0.011	0.936TrpGly: 0.936 ± 0.014	0.31TrpHis: 0.31 ± 0.007	0.782TrpIle: 0.782 ± 0.013	0.865TrpLys: 0.865 ± 0.015	1.182TrpLeu: 1.182 ± 0.017	0.364TrpMet: 0.364 ± 0.009	0.662TrpAsn: 0.662 ± 0.012	0.514TrpPro: 0.514 ± 0.011	0.503TrpGln: 0.503 ± 0.009	0.824TrpArg: 0.824 ± 0.013	0.985TrpSer: 0.985 ± 0.015	0.836TrpThr: 0.836 ± 0.014	0.784TrpVal: 0.784 ± 0.014	0.252TrpTrp: 0.252 ± 0.008	0.399TrpTyr: 0.399 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.982TyrAla: 1.982 ± 0.022	0.428TyrCys: 0.428 ± 0.01	1.68TyrAsp: 1.68 ± 0.02	1.683TyrGlu: 1.683 ± 0.019	1.209TyrPhe: 1.209 ± 0.018	2.055TyrGly: 2.055 ± 0.023	0.737TyrHis: 0.737 ± 0.014	1.526TyrIle: 1.526 ± 0.02	1.276TyrLys: 1.276 ± 0.017	2.533TyrLeu: 2.533 ± 0.025	0.614TyrMet: 0.614 ± 0.012	1.304TyrAsn: 1.304 ± 0.016	1.511TyrPro: 1.511 ± 0.021	1.154TyrGln: 1.154 ± 0.017	1.513TyrArg: 1.513 ± 0.017	2.197TyrSer: 2.197 ± 0.022	1.758TyrThr: 1.758 ± 0.021	1.523TyrVal: 1.523 ± 0.018	0.418TyrTrp: 0.418 ± 0.009	0.954TyrTyr: 0.954 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 11857 proteins (5343889 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---