Human papillomavirus 93

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Betapapillomavirus; Betapapillomavirus 1

Average proteome isoelectric point is 5.95

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q6TY36|Q6TY36_9PAPI Protein E6 OS=Human papillomavirus 93 OX=247268 GN=E6 PE=3 SV=1
MM1 pKa = 7.37IGKK4 pKa = 8.93EE5 pKa = 3.9VTLQDD10 pKa = 3.25IVLGLTPPEE19 pKa = 3.95PVALNCEE26 pKa = 4.31EE27 pKa = 4.39EE28 pKa = 4.91LPTEE32 pKa = 4.0QDD34 pKa = 3.37TEE36 pKa = 4.24EE37 pKa = 4.38EE38 pKa = 4.17PARR41 pKa = 11.84TAFKK45 pKa = 10.46IIVFCGGGCGSRR57 pKa = 11.84LRR59 pKa = 11.84IFVAATEE66 pKa = 4.15FGVRR70 pKa = 11.84CFQQLLVKK78 pKa = 10.2EE79 pKa = 4.73LDD81 pKa = 4.01LLCPNCRR88 pKa = 11.84NSDD91 pKa = 3.87LQHH94 pKa = 6.61GGQQ97 pKa = 3.6

Molecular weight: 10.65 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|Q6TY34|Q6TY34_9PAPI Replication protein E1 OS=Human papillomavirus 93 OX=247268 GN=E1 PE=3 SV=1
MM1 pKa = 6.59EE2 pKa = 4.56TLRR5 pKa = 11.84EE6 pKa = 4.06RR7 pKa = 11.84FDD9 pKa = 3.56VLQDD13 pKa = 3.26QLMNIYY19 pKa = 9.69EE20 pKa = 4.36VASDD24 pKa = 3.5TLEE27 pKa = 3.89AQIEE31 pKa = 4.24HH32 pKa = 6.31WRR34 pKa = 11.84LLRR37 pKa = 11.84KK38 pKa = 9.23EE39 pKa = 4.18AVLLYY44 pKa = 8.99FARR47 pKa = 11.84QNGVLRR53 pKa = 11.84LGYY56 pKa = 10.31QPVPPLATSEE66 pKa = 4.35AKK68 pKa = 10.45AKK70 pKa = 9.92EE71 pKa = 4.49AIGMMLQLQSLQKK84 pKa = 10.19SAYY87 pKa = 9.84ASEE90 pKa = 3.96KK91 pKa = 7.62WTLVDD96 pKa = 3.78TSIEE100 pKa = 4.32TFKK103 pKa = 10.35NTPEE107 pKa = 3.73NHH109 pKa = 6.11FKK111 pKa = 10.73KK112 pKa = 10.7GPVNVEE118 pKa = 3.83VIYY121 pKa = 11.2DD122 pKa = 4.14GDD124 pKa = 4.07PDD126 pKa = 3.81NANLYY131 pKa = 8.07TMWKK135 pKa = 7.81YY136 pKa = 11.35VYY138 pKa = 10.55YY139 pKa = 10.55LDD141 pKa = 5.93SEE143 pKa = 4.99DD144 pKa = 3.7RR145 pKa = 11.84WQKK148 pKa = 9.18TEE150 pKa = 3.57SGANHH155 pKa = 6.03TGIYY159 pKa = 8.44YY160 pKa = 8.7TIKK163 pKa = 10.57DD164 pKa = 3.77FKK166 pKa = 10.91HH167 pKa = 6.43YY168 pKa = 8.5YY169 pKa = 9.45TLFADD174 pKa = 4.09DD175 pKa = 3.56AKK177 pKa = 11.05KK178 pKa = 10.63YY179 pKa = 10.05GKK181 pKa = 9.88SGQWEE186 pKa = 3.89VRR188 pKa = 11.84INKK191 pKa = 7.16EE192 pKa = 4.11TVFAPVTSSTPPEE205 pKa = 4.08SPGRR209 pKa = 11.84EE210 pKa = 3.53RR211 pKa = 11.84ASPEE215 pKa = 3.92STAHH219 pKa = 5.85TKK221 pKa = 7.25TTARR225 pKa = 11.84SSASPDD231 pKa = 3.23HH232 pKa = 6.67EE233 pKa = 5.22LPQQTSDD240 pKa = 2.87EE241 pKa = 4.57TNRR244 pKa = 11.84KK245 pKa = 8.2RR246 pKa = 11.84RR247 pKa = 11.84YY248 pKa = 9.09GRR250 pKa = 11.84RR251 pKa = 11.84EE252 pKa = 3.74SSPTEE257 pKa = 3.95SKK259 pKa = 10.29RR260 pKa = 11.84KK261 pKa = 9.19RR262 pKa = 11.84RR263 pKa = 11.84RR264 pKa = 11.84SSSRR268 pKa = 11.84QKK270 pKa = 9.84KK271 pKa = 7.6QGRR274 pKa = 11.84RR275 pKa = 11.84SRR277 pKa = 11.84SRR279 pKa = 11.84TTSSQSRR286 pKa = 11.84SRR288 pKa = 11.84SRR290 pKa = 11.84SSSSRR295 pKa = 11.84GSRR298 pKa = 11.84GSRR301 pKa = 11.84GRR303 pKa = 11.84TPRR306 pKa = 11.84GRR308 pKa = 11.84GKK310 pKa = 8.46HH311 pKa = 3.89TTRR314 pKa = 11.84GRR316 pKa = 11.84GRR318 pKa = 11.84GSGRR322 pKa = 11.84KK323 pKa = 8.41GDD325 pKa = 3.37RR326 pKa = 11.84RR327 pKa = 11.84GRR329 pKa = 11.84RR330 pKa = 11.84SRR332 pKa = 11.84RR333 pKa = 11.84SSSSSSPTICTRR345 pKa = 11.84SASQTRR351 pKa = 11.84SKK353 pKa = 10.69QSKK356 pKa = 8.05CARR359 pKa = 11.84DD360 pKa = 3.79GGISPGDD367 pKa = 3.45VGRR370 pKa = 11.84SVQTVSGRR378 pKa = 11.84NTGRR382 pKa = 11.84LGRR385 pKa = 11.84LLEE388 pKa = 4.17EE389 pKa = 4.57ARR391 pKa = 11.84DD392 pKa = 3.73PPVILIRR399 pKa = 11.84GEE401 pKa = 4.09ANTVKK406 pKa = 10.54CFRR409 pKa = 11.84NRR411 pKa = 11.84AKK413 pKa = 10.32QKK415 pKa = 11.09YY416 pKa = 9.3KK417 pKa = 10.64GLCKK421 pKa = 10.39AFSTTWSWVAADD433 pKa = 3.41GTEE436 pKa = 3.7RR437 pKa = 11.84LGRR440 pKa = 11.84SRR442 pKa = 11.84VLVSFTSHH450 pKa = 5.1TQRR453 pKa = 11.84SSFLKK458 pKa = 10.05VVKK461 pKa = 10.2FPKK464 pKa = 10.48GVDD467 pKa = 3.05WSLGNLDD474 pKa = 4.16KK475 pKa = 11.47LL476 pKa = 4.08

Molecular weight: 53.93 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2572

97

603

367.4

41.34

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.404 ± 0.371

1.944 ± 0.827

5.793 ± 0.397

6.882 ± 0.82

3.771 ± 0.54

6.61 ± 0.744

1.75 ± 0.3

4.238 ± 0.574

5.21 ± 0.853

8.826 ± 0.972

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.439 ± 0.417

4.471 ± 0.866

6.415 ± 1.315

4.977 ± 0.299

6.882 ± 1.47

8.32 ± 1.251

6.26 ± 0.721

6.182 ± 0.638

1.283 ± 0.347

3.344 ± 0.491
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski