Cyclovirus ZM54

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Arfiviricetes; Cirlivirales; Circoviridae; Cyclovirus; Human associated cyclovirus 8; Cyclovirus VN

Average proteome isoelectric point is 8.39

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A097ZPG0|A0A097ZPG0_9CIRC ATP-dependent helicase Rep OS=Cyclovirus ZM54 OX=1506572 GN=Rep PE=3 SV=1
MM1 pKa = 7.72ANNSTVRR8 pKa = 11.84RR9 pKa = 11.84FCWTLNNYY17 pKa = 8.05TDD19 pKa = 3.69EE20 pKa = 5.01DD21 pKa = 4.2VDD23 pKa = 4.45VLQKK27 pKa = 11.03DD28 pKa = 3.5LAEE31 pKa = 4.3LCKK34 pKa = 10.04FAIFGRR40 pKa = 11.84EE41 pKa = 3.98TCPSTGTKK49 pKa = 9.84HH50 pKa = 6.5LQGFCNLQRR59 pKa = 11.84PKK61 pKa = 10.55RR62 pKa = 11.84FNSIRR67 pKa = 11.84KK68 pKa = 8.22IFGGRR73 pKa = 11.84AHH75 pKa = 7.25IEE77 pKa = 3.88RR78 pKa = 11.84AKK80 pKa = 10.43GTDD83 pKa = 3.2IEE85 pKa = 4.27NKK87 pKa = 9.52EE88 pKa = 4.12YY89 pKa = 10.47CSKK92 pKa = 11.3GGDD95 pKa = 3.17VWEE98 pKa = 5.31CGTPSAQGTRR108 pKa = 11.84TDD110 pKa = 3.51LQKK113 pKa = 10.72VVSVIEE119 pKa = 4.35GGEE122 pKa = 4.27TCLKK126 pKa = 9.47TLAIQFPVAYY136 pKa = 8.98IKK138 pKa = 10.47YY139 pKa = 9.54FKK141 pKa = 10.79GIEE144 pKa = 3.78QYY146 pKa = 10.83IRR148 pKa = 11.84IAHH151 pKa = 6.42GNPEE155 pKa = 4.27RR156 pKa = 11.84DD157 pKa = 3.64FKK159 pKa = 10.97TKK161 pKa = 10.03VYY163 pKa = 9.76YY164 pKa = 10.45FWGCTGTGKK173 pKa = 9.98SRR175 pKa = 11.84KK176 pKa = 9.39ARR178 pKa = 11.84EE179 pKa = 3.7EE180 pKa = 3.96SLALGDD186 pKa = 3.69TYY188 pKa = 11.35YY189 pKa = 11.01KK190 pKa = 10.5PRR192 pKa = 11.84GEE194 pKa = 3.75WWDD197 pKa = 3.93GYY199 pKa = 9.14TGQPCVVIDD208 pKa = 5.82DD209 pKa = 4.49FYY211 pKa = 11.88GWIKK215 pKa = 10.75YY216 pKa = 10.28DD217 pKa = 4.1EE218 pKa = 4.44LLKK221 pKa = 10.71ICDD224 pKa = 3.7RR225 pKa = 11.84YY226 pKa = 10.06PYY228 pKa = 9.86RR229 pKa = 11.84VPVKK233 pKa = 10.11GGYY236 pKa = 9.11EE237 pKa = 3.94NFVSKK242 pKa = 10.37HH243 pKa = 3.85IWITSEE249 pKa = 3.95RR250 pKa = 11.84PLEE253 pKa = 3.76EE254 pKa = 3.8VYY256 pKa = 10.82RR257 pKa = 11.84FISYY261 pKa = 10.25DD262 pKa = 3.34CSSLRR267 pKa = 11.84RR268 pKa = 11.84RR269 pKa = 11.84LNKK272 pKa = 9.94EE273 pKa = 3.29IHH275 pKa = 6.23FEE277 pKa = 3.93

Molecular weight: 32.22 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A097ZPG0|A0A097ZPG0_9CIRC ATP-dependent helicase Rep OS=Cyclovirus ZM54 OX=1506572 GN=Rep PE=3 SV=1
MM1 pKa = 7.57APRR4 pKa = 11.84RR5 pKa = 11.84RR6 pKa = 11.84TVRR9 pKa = 11.84RR10 pKa = 11.84RR11 pKa = 11.84APIRR15 pKa = 11.84RR16 pKa = 11.84RR17 pKa = 11.84RR18 pKa = 11.84RR19 pKa = 11.84VIRR22 pKa = 11.84RR23 pKa = 11.84RR24 pKa = 11.84RR25 pKa = 11.84LRR27 pKa = 11.84NFRR30 pKa = 11.84RR31 pKa = 11.84RR32 pKa = 11.84PRR34 pKa = 11.84TGNFTLLVRR43 pKa = 11.84DD44 pKa = 4.0TSVHH48 pKa = 6.04GIKK51 pKa = 9.8PAEE54 pKa = 4.53GSTVPIYY61 pKa = 10.52PRR63 pKa = 11.84INDD66 pKa = 3.39FKK68 pKa = 11.21EE69 pKa = 3.88AVPYY73 pKa = 10.12LAYY76 pKa = 10.42FEE78 pKa = 4.92SYY80 pKa = 9.48KK81 pKa = 10.32IHH83 pKa = 6.66WISVKK88 pKa = 10.19VSPLFNVAEE97 pKa = 4.37PSQPVPRR104 pKa = 11.84YY105 pKa = 10.23YY106 pKa = 9.8STPWHH111 pKa = 6.09RR112 pKa = 11.84TPPTIINTNTILSLDD127 pKa = 3.7RR128 pKa = 11.84AKK130 pKa = 10.61SHH132 pKa = 6.71HH133 pKa = 6.47GCSSSFRR140 pKa = 11.84RR141 pKa = 11.84FVPAVLTTSNVVGEE155 pKa = 4.27PTAHH159 pKa = 6.44IGKK162 pKa = 9.84INWRR166 pKa = 11.84PKK168 pKa = 9.77IAFDD172 pKa = 3.78STGQSIRR179 pKa = 11.84HH180 pKa = 4.66YY181 pKa = 10.28CGFYY185 pKa = 10.34HH186 pKa = 7.1FSVDD190 pKa = 5.25QIPLPNAALRR200 pKa = 11.84QYY202 pKa = 10.53EE203 pKa = 4.08FEE205 pKa = 3.96ITAKK209 pKa = 8.74ITLYY213 pKa = 9.68NQKK216 pKa = 10.35SFAA219 pKa = 4.08

Molecular weight: 25.56 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2

0

2

496

219

277

248.0

28.89

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.04 ± 0.844

2.621 ± 1.065

4.032 ± 1.091

5.645 ± 1.528

5.242 ± 0.148

6.452 ± 1.746

2.621 ± 0.644

7.056 ± 0.44

6.25 ± 1.335

5.444 ± 0.262

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

0.403 ± 0.033

4.032 ± 0.333

5.847 ± 1.765

2.621 ± 0.211

10.282 ± 2.131

6.048 ± 1.069

6.855 ± 0.281

6.048 ± 0.5

2.016 ± 0.403

5.444 ± 0.547
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski