Amino acid dipepetide frequency for Thalassotalea agarivorans (Thalassomonas agarivorans)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.315AlaAla: 7.315 ± 0.106	0.957AlaCys: 0.957 ± 0.034	4.906AlaAsp: 4.906 ± 0.074	5.385AlaGlu: 5.385 ± 0.093	3.885AlaPhe: 3.885 ± 0.061	5.843AlaGly: 5.843 ± 0.086	1.759AlaHis: 1.759 ± 0.042	6.599AlaIle: 6.599 ± 0.094	5.444AlaLys: 5.444 ± 0.094	9.764AlaLeu: 9.764 ± 0.134	2.48AlaMet: 2.48 ± 0.051	4.098AlaAsn: 4.098 ± 0.079	2.977AlaPro: 2.977 ± 0.063	4.363AlaGln: 4.363 ± 0.081	3.39AlaArg: 3.39 ± 0.071	5.51AlaSer: 5.51 ± 0.078	4.811AlaThr: 4.811 ± 0.077	5.834AlaVal: 5.834 ± 0.087	0.973AlaTrp: 0.973 ± 0.035	2.64AlaTyr: 2.64 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	0.769CysAla: 0.769 ± 0.027	0.132CysCys: 0.132 ± 0.012	0.535CysAsp: 0.535 ± 0.024	0.535CysGlu: 0.535 ± 0.023	0.424CysPhe: 0.424 ± 0.022	0.783CysGly: 0.783 ± 0.034	0.296CysHis: 0.296 ± 0.018	0.568CysIle: 0.568 ± 0.026	0.425CysLys: 0.425 ± 0.023	0.905CysLeu: 0.905 ± 0.029	0.216CysMet: 0.216 ± 0.015	0.382CysAsn: 0.382 ± 0.018	0.42CysPro: 0.42 ± 0.023	0.466CysGln: 0.466 ± 0.022	0.352CysArg: 0.352 ± 0.021	0.609CysSer: 0.609 ± 0.026	0.45CysThr: 0.45 ± 0.022	0.55CysVal: 0.55 ± 0.025	0.12CysTrp: 0.12 ± 0.012	0.317CysTyr: 0.317 ± 0.022	0.0CysXaa: 0.0 ± 0.0
Asp	4.985AspAla: 4.985 ± 0.086	0.491AspCys: 0.491 ± 0.026	3.518AspAsp: 3.518 ± 0.07	3.905AspGlu: 3.905 ± 0.073	2.769AspPhe: 2.769 ± 0.059	3.984AspGly: 3.984 ± 0.091	1.069AspHis: 1.069 ± 0.037	4.881AspIle: 4.881 ± 0.079	3.782AspLys: 3.782 ± 0.067	5.014AspLeu: 5.014 ± 0.074	1.518AspMet: 1.518 ± 0.038	2.882AspAsn: 2.882 ± 0.053	2.01AspPro: 2.01 ± 0.054	2.02AspGln: 2.02 ± 0.05	2.042AspArg: 2.042 ± 0.051	3.286AspSer: 3.286 ± 0.061	3.009AspThr: 3.009 ± 0.067	4.42AspVal: 4.42 ± 0.068	0.884AspTrp: 0.884 ± 0.029	2.236AspTyr: 2.236 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	5.015GluAla: 5.015 ± 0.084	0.39GluCys: 0.39 ± 0.022	3.234GluAsp: 3.234 ± 0.059	3.906GluGlu: 3.906 ± 0.086	2.397GluPhe: 2.397 ± 0.056	3.531GluGly: 3.531 ± 0.069	1.568GluHis: 1.568 ± 0.041	3.839GluIle: 3.839 ± 0.062	4.156GluLys: 4.156 ± 0.073	6.131GluLeu: 6.131 ± 0.089	1.536GluMet: 1.536 ± 0.039	3.016GluAsn: 3.016 ± 0.057	1.717GluPro: 1.717 ± 0.041	4.706GluGln: 4.706 ± 0.078	2.721GluArg: 2.721 ± 0.063	3.593GluSer: 3.593 ± 0.062	3.177GluThr: 3.177 ± 0.059	4.072GluVal: 4.072 ± 0.065	0.558GluTrp: 0.558 ± 0.024	1.757GluTyr: 1.757 ± 0.044	0.0GluXaa: 0.0 ± 0.0
Phe	3.933PheAla: 3.933 ± 0.069	0.516PheCys: 0.516 ± 0.025	3.203PheAsp: 3.203 ± 0.05	2.802PheGlu: 2.802 ± 0.056	1.964PhePhe: 1.964 ± 0.05	3.205PheGly: 3.205 ± 0.071	0.84PheHis: 0.84 ± 0.029	2.997PheIle: 2.997 ± 0.056	2.289PheLys: 2.289 ± 0.054	3.465PheLeu: 3.465 ± 0.064	0.976PheMet: 0.976 ± 0.031	2.376PheAsn: 2.376 ± 0.06	1.422PhePro: 1.422 ± 0.037	1.253PheGln: 1.253 ± 0.035	1.404PheArg: 1.404 ± 0.042	3.382PheSer: 3.382 ± 0.066	2.654PheThr: 2.654 ± 0.057	3.258PheVal: 3.258 ± 0.061	0.577PheTrp: 0.577 ± 0.026	1.564PheTyr: 1.564 ± 0.041	0.0PheXaa: 0.0 ± 0.0
Gly	5.253GlyAla: 5.253 ± 0.087	0.752GlyCys: 0.752 ± 0.03	3.984GlyAsp: 3.984 ± 0.077	4.436GlyGlu: 4.436 ± 0.075	3.486GlyPhe: 3.486 ± 0.059	4.733GlyGly: 4.733 ± 0.086	1.553GlyHis: 1.553 ± 0.04	4.636GlyIle: 4.636 ± 0.074	4.134GlyLys: 4.134 ± 0.075	6.339GlyLeu: 6.339 ± 0.089	1.799GlyMet: 1.799 ± 0.046	2.823GlyAsn: 2.823 ± 0.064	1.625GlyPro: 1.625 ± 0.044	2.713GlyGln: 2.713 ± 0.054	2.747GlyArg: 2.747 ± 0.054	3.89GlySer: 3.89 ± 0.074	3.373GlyThr: 3.373 ± 0.07	4.959GlyVal: 4.959 ± 0.074	0.941GlyTrp: 0.941 ± 0.028	2.609GlyTyr: 2.609 ± 0.054	0.0GlyXaa: 0.0 ± 0.0
His	1.699HisAla: 1.699 ± 0.043	0.317HisCys: 0.317 ± 0.019	1.159HisAsp: 1.159 ± 0.036	1.046HisGlu: 1.046 ± 0.036	1.124HisPhe: 1.124 ± 0.034	1.55HisGly: 1.55 ± 0.044	0.636HisHis: 0.636 ± 0.033	1.521HisIle: 1.521 ± 0.039	1.114HisLys: 1.114 ± 0.034	2.109HisLeu: 2.109 ± 0.053	0.515HisMet: 0.515 ± 0.024	0.934HisAsn: 0.934 ± 0.029	1.03HisPro: 1.03 ± 0.038	1.227HisGln: 1.227 ± 0.041	0.888HisArg: 0.888 ± 0.031	1.271HisSer: 1.271 ± 0.036	1.002HisThr: 1.002 ± 0.031	1.424HisVal: 1.424 ± 0.041	0.369HisTrp: 0.369 ± 0.021	0.868HisTyr: 0.868 ± 0.033	0.0HisXaa: 0.0 ± 0.0
Ile	7.116IleAla: 7.116 ± 0.101	0.596IleCys: 0.596 ± 0.025	4.802IleAsp: 4.802 ± 0.074	4.879IleGlu: 4.879 ± 0.064	2.365IlePhe: 2.365 ± 0.054	4.534IleGly: 4.534 ± 0.079	1.243IleHis: 1.243 ± 0.042	3.736IleIle: 3.736 ± 0.07	3.777IleLys: 3.777 ± 0.07	5.084IleLeu: 5.084 ± 0.076	1.256IleMet: 1.256 ± 0.037	3.273IleAsn: 3.273 ± 0.055	2.551IlePro: 2.551 ± 0.051	1.994IleGln: 1.994 ± 0.046	2.531IleArg: 2.531 ± 0.057	4.547IleSer: 4.547 ± 0.078	3.814IleThr: 3.814 ± 0.073	4.719IleVal: 4.719 ± 0.069	0.618IleTrp: 0.618 ± 0.028	1.837IleTyr: 1.837 ± 0.044	0.0IleXaa: 0.0 ± 0.0
Lys	5.563LysAla: 5.563 ± 0.105	0.325LysCys: 0.325 ± 0.021	3.117LysAsp: 3.117 ± 0.06	3.383LysGlu: 3.383 ± 0.059	1.863LysPhe: 1.863 ± 0.046	3.536LysGly: 3.536 ± 0.068	1.497LysHis: 1.497 ± 0.042	3.121LysIle: 3.121 ± 0.061	3.305LysLys: 3.305 ± 0.079	5.417LysLeu: 5.417 ± 0.082	1.437LysMet: 1.437 ± 0.038	2.362LysAsn: 2.362 ± 0.052	2.503LysPro: 2.503 ± 0.059	3.7LysGln: 3.7 ± 0.076	2.672LysArg: 2.672 ± 0.057	3.343LysSer: 3.343 ± 0.062	3.311LysThr: 3.311 ± 0.06	3.916LysVal: 3.916 ± 0.065	0.631LysTrp: 0.631 ± 0.026	1.74LysTyr: 1.74 ± 0.047	0.0LysXaa: 0.0 ± 0.0
Leu	9.996LeuAla: 9.996 ± 0.115	0.906LeuCys: 0.906 ± 0.03	5.593LeuAsp: 5.593 ± 0.088	5.28LeuGlu: 5.28 ± 0.074	4.307LeuPhe: 4.307 ± 0.083	6.323LeuGly: 6.323 ± 0.092	1.839LeuHis: 1.839 ± 0.044	6.053LeuIle: 6.053 ± 0.097	5.354LeuLys: 5.354 ± 0.075	9.674LeuLeu: 9.674 ± 0.139	2.373LeuMet: 2.373 ± 0.052	4.427LeuAsn: 4.427 ± 0.062	4.574LeuPro: 4.574 ± 0.066	3.283LeuGln: 3.283 ± 0.068	3.621LeuArg: 3.621 ± 0.06	7.677LeuSer: 7.677 ± 0.085	6.138LeuThr: 6.138 ± 0.076	6.936LeuVal: 6.936 ± 0.1	0.991LeuTrp: 0.991 ± 0.032	2.807LeuTyr: 2.807 ± 0.055	0.0LeuXaa: 0.0 ± 0.0
Met	2.417MetAla: 2.417 ± 0.055	0.213MetCys: 0.213 ± 0.015	1.198MetAsp: 1.198 ± 0.039	1.208MetGlu: 1.208 ± 0.038	0.957MetPhe: 0.957 ± 0.029	1.57MetGly: 1.57 ± 0.036	0.521MetHis: 0.521 ± 0.024	1.343MetIle: 1.343 ± 0.039	1.461MetLys: 1.461 ± 0.041	2.551MetLeu: 2.551 ± 0.053	0.652MetMet: 0.652 ± 0.031	1.005MetAsn: 1.005 ± 0.031	1.303MetPro: 1.303 ± 0.041	1.088MetGln: 1.088 ± 0.034	1.083MetArg: 1.083 ± 0.034	1.793MetSer: 1.793 ± 0.041	1.47MetThr: 1.47 ± 0.04	1.669MetVal: 1.669 ± 0.041	0.257MetTrp: 0.257 ± 0.015	0.623MetTyr: 0.623 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.904AsnAla: 3.904 ± 0.068	0.418AsnCys: 0.418 ± 0.025	2.628AsnAsp: 2.628 ± 0.057	2.724AsnGlu: 2.724 ± 0.06	1.807AsnPhe: 1.807 ± 0.044	3.145AsnGly: 3.145 ± 0.069	0.919AsnHis: 0.919 ± 0.032	3.191AsnIle: 3.191 ± 0.058	2.763AsnLys: 2.763 ± 0.06	4.019AsnLeu: 4.019 ± 0.066	1.06AsnMet: 1.06 ± 0.036	2.237AsnAsn: 2.237 ± 0.061	2.065AsnPro: 2.065 ± 0.049	2.298AsnGln: 2.298 ± 0.055	1.827AsnArg: 1.827 ± 0.041	2.402AsnSer: 2.402 ± 0.055	2.539AsnThr: 2.539 ± 0.05	3.2AsnVal: 3.2 ± 0.054	0.609AsnTrp: 0.609 ± 0.025	1.538AsnTyr: 1.538 ± 0.041	0.0AsnXaa: 0.0 ± 0.0
Pro	3.17ProAla: 3.17 ± 0.071	0.307ProCys: 0.307 ± 0.019	2.263ProAsp: 2.263 ± 0.049	2.884ProGlu: 2.884 ± 0.063	1.801ProPhe: 1.801 ± 0.047	2.257ProGly: 2.257 ± 0.053	0.824ProHis: 0.824 ± 0.027	2.468ProIle: 2.468 ± 0.05	2.005ProLys: 2.005 ± 0.047	3.8ProLeu: 3.8 ± 0.06	0.917ProMet: 0.917 ± 0.03	1.868ProAsn: 1.868 ± 0.044	1.093ProPro: 1.093 ± 0.036	1.671ProGln: 1.671 ± 0.043	1.243ProArg: 1.243 ± 0.039	2.464ProSer: 2.464 ± 0.054	2.079ProThr: 2.079 ± 0.046	2.936ProVal: 2.936 ± 0.056	0.535ProTrp: 0.535 ± 0.027	1.397ProTyr: 1.397 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	4.477GlnAla: 4.477 ± 0.072	0.394GlnCys: 0.394 ± 0.021	2.312GlnAsp: 2.312 ± 0.047	2.488GlnGlu: 2.488 ± 0.054	1.881GlnPhe: 1.881 ± 0.049	3.048GlnGly: 3.048 ± 0.062	1.295GlnHis: 1.295 ± 0.042	2.55GlnIle: 2.55 ± 0.054	2.298GlnLys: 2.298 ± 0.055	5.177GlnLeu: 5.177 ± 0.082	1.094GlnMet: 1.094 ± 0.032	1.658GlnAsn: 1.658 ± 0.041	1.625GlnPro: 1.625 ± 0.041	3.471GlnGln: 3.471 ± 0.094	2.006GlnArg: 2.006 ± 0.051	2.866GlnSer: 2.866 ± 0.065	2.296GlnThr: 2.296 ± 0.046	3.351GlnVal: 3.351 ± 0.055	0.761GlnTrp: 0.761 ± 0.027	1.564GlnTyr: 1.564 ± 0.039	0.0GlnXaa: 0.0 ± 0.0
Arg	3.118ArgAla: 3.118 ± 0.054	0.323ArgCys: 0.323 ± 0.014	2.225ArgAsp: 2.225 ± 0.05	2.51ArgGlu: 2.51 ± 0.06	2.04ArgPhe: 2.04 ± 0.044	2.353ArgGly: 2.353 ± 0.049	0.928ArgHis: 0.928 ± 0.032	2.818ArgIle: 2.818 ± 0.058	2.343ArgLys: 2.343 ± 0.048	4.105ArgLeu: 4.105 ± 0.07	1.046ArgMet: 1.046 ± 0.037	1.73ArgAsn: 1.73 ± 0.042	1.359ArgPro: 1.359 ± 0.041	1.817ArgGln: 1.817 ± 0.049	1.938ArgArg: 1.938 ± 0.054	2.262ArgSer: 2.262 ± 0.051	1.917ArgThr: 1.917 ± 0.046	2.881ArgVal: 2.881 ± 0.058	0.536ArgTrp: 0.536 ± 0.022	1.667ArgTyr: 1.667 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	5.613SerAla: 5.613 ± 0.08	0.61SerCys: 0.61 ± 0.025	3.828SerAsp: 3.828 ± 0.07	3.797SerGlu: 3.797 ± 0.061	3.131SerPhe: 3.131 ± 0.06	4.823SerGly: 4.823 ± 0.085	1.402SerHis: 1.402 ± 0.04	4.066SerIle: 4.066 ± 0.07	3.416SerLys: 3.416 ± 0.061	6.665SerLeu: 6.665 ± 0.074	1.598SerMet: 1.598 ± 0.043	2.822SerAsn: 2.822 ± 0.066	2.465SerPro: 2.465 ± 0.05	2.855SerGln: 2.855 ± 0.062	2.441SerArg: 2.441 ± 0.056	4.052SerSer: 4.052 ± 0.078	3.312SerThr: 3.312 ± 0.06	4.433SerVal: 4.433 ± 0.074	0.771SerTrp: 0.771 ± 0.031	2.238SerTyr: 2.238 ± 0.055	0.0SerXaa: 0.0 ± 0.0
Thr	4.54ThrAla: 4.54 ± 0.077	0.426ThrCys: 0.426 ± 0.021	3.177ThrAsp: 3.177 ± 0.072	3.013ThrGlu: 3.013 ± 0.062	2.513ThrPhe: 2.513 ± 0.045	4.006ThrGly: 4.006 ± 0.065	1.112ThrHis: 1.112 ± 0.035	3.717ThrIle: 3.717 ± 0.055	2.61ThrLys: 2.61 ± 0.052	6.303ThrLeu: 6.303 ± 0.085	1.161ThrMet: 1.161 ± 0.035	2.291ThrAsn: 2.291 ± 0.055	2.75ThrPro: 2.75 ± 0.055	2.291ThrGln: 2.291 ± 0.047	2.078ThrArg: 2.078 ± 0.042	3.451ThrSer: 3.451 ± 0.063	3.042ThrThr: 3.042 ± 0.06	4.017ThrVal: 4.017 ± 0.062	0.654ThrTrp: 0.654 ± 0.022	1.671ThrTyr: 1.671 ± 0.044	0.001ThrXaa: 0.001 ± 0.001
Val	6.789ValAla: 6.789 ± 0.096	0.698ValCys: 0.698 ± 0.028	4.484ValAsp: 4.484 ± 0.079	4.689ValGlu: 4.689 ± 0.075	3.14ValPhe: 3.14 ± 0.07	4.512ValGly: 4.512 ± 0.072	1.278ValHis: 1.278 ± 0.035	4.636ValIle: 4.636 ± 0.069	3.937ValLys: 3.937 ± 0.066	6.654ValLeu: 6.654 ± 0.1	1.704ValMet: 1.704 ± 0.044	3.345ValAsn: 3.345 ± 0.058	2.62ValPro: 2.62 ± 0.051	2.213ValGln: 2.213 ± 0.05	2.587ValArg: 2.587 ± 0.055	5.097ValSer: 5.097 ± 0.07	4.238ValThr: 4.238 ± 0.06	5.44ValVal: 5.44 ± 0.091	0.746ValTrp: 0.746 ± 0.031	2.107ValTyr: 2.107 ± 0.053	0.0ValXaa: 0.0 ± 0.0
Trp	0.768TrpAla: 0.768 ± 0.029	0.13TrpCys: 0.13 ± 0.013	0.609TrpAsp: 0.609 ± 0.025	0.48TrpGlu: 0.48 ± 0.025	0.591TrpPhe: 0.591 ± 0.027	0.813TrpGly: 0.813 ± 0.032	0.41TrpHis: 0.41 ± 0.023	0.661TrpIle: 0.661 ± 0.029	0.468TrpLys: 0.468 ± 0.022	1.589TrpLeu: 1.589 ± 0.041	0.331TrpMet: 0.331 ± 0.019	0.42TrpAsn: 0.42 ± 0.022	0.452TrpPro: 0.452 ± 0.021	1.151TrpGln: 1.151 ± 0.044	0.666TrpArg: 0.666 ± 0.027	0.691TrpSer: 0.691 ± 0.033	0.536TrpThr: 0.536 ± 0.024	0.793TrpVal: 0.793 ± 0.028	0.164TrpTrp: 0.164 ± 0.013	0.451TrpTyr: 0.451 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.492TyrAla: 2.492 ± 0.05	0.352TyrCys: 0.352 ± 0.019	1.932TyrAsp: 1.932 ± 0.052	1.67TyrGlu: 1.67 ± 0.041	1.633TyrPhe: 1.633 ± 0.044	2.237TyrGly: 2.237 ± 0.05	0.812TyrHis: 0.812 ± 0.026	1.867TyrIle: 1.867 ± 0.043	1.658TyrLys: 1.658 ± 0.046	3.388TyrLeu: 3.388 ± 0.065	0.714TyrMet: 0.714 ± 0.029	1.348TyrAsn: 1.348 ± 0.041	1.418TyrPro: 1.418 ± 0.042	2.035TyrGln: 2.035 ± 0.05	1.68TyrArg: 1.68 ± 0.04	2.153TyrSer: 2.153 ± 0.053	1.657TyrThr: 1.657 ± 0.046	2.106TyrVal: 2.106 ± 0.051	0.479TyrTrp: 0.479 ± 0.02	1.188TyrTyr: 1.188 ± 0.034	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.001	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.003XaaXaa: 0.003 ± 0.003

Statistics based on 2994 proteins (993003 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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