Amino acid dipepetide frequency for Torque teno virus 14

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.795AlaAla: 7.795 ± 7.055
0.0AlaCys: 0.0 ± 0.0
4.454AlaAsp: 4.454 ± 5.06
1.114AlaGlu: 1.114 ± 0.535
1.114AlaPhe: 1.114 ± 3.065
8.909AlaGly: 8.909 ± 20.921
1.114AlaHis: 1.114 ± 0.535
0.0AlaIle: 0.0 ± 0.0
1.114AlaLys: 1.114 ± 0.535
7.795AlaLeu: 7.795 ± 3.454
0.0AlaMet: 0.0 ± 0.0
1.114AlaAsn: 1.114 ± 0.535
4.454AlaPro: 4.454 ± 5.06
4.454AlaGln: 4.454 ± 2.141
6.682AlaArg: 6.682 ± 3.212
2.227AlaSer: 2.227 ± 1.071
1.114AlaThr: 1.114 ± 0.535
4.454AlaVal: 4.454 ± 5.06
0.0AlaTrp: 0.0 ± 0.0
4.454AlaTyr: 4.454 ± 2.141
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.114CysAsp: 1.114 ± 0.535
0.0CysGlu: 0.0 ± 0.0
1.114CysPhe: 1.114 ± 3.065
4.454CysGly: 4.454 ± 5.06
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.114CysLys: 1.114 ± 0.535
4.454CysLeu: 4.454 ± 2.141
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.114CysPro: 1.114 ± 0.535
1.114CysGln: 1.114 ± 0.535
3.341CysArg: 3.341 ± 1.995
2.227CysSer: 2.227 ± 1.071
0.0CysThr: 0.0 ± 0.0
1.114CysVal: 1.114 ± 0.535
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.227AspAla: 2.227 ± 6.13
1.114AspCys: 1.114 ± 0.535
2.227AspAsp: 2.227 ± 1.071
7.795AspGlu: 7.795 ± 0.146
3.341AspPhe: 3.341 ± 1.606
1.114AspGly: 1.114 ± 0.535
0.0AspHis: 0.0 ± 0.0
1.114AspIle: 1.114 ± 0.535
1.114AspLys: 1.114 ± 0.535
7.795AspLeu: 7.795 ± 3.747
0.0AspMet: 0.0 ± 0.0
4.454AspAsn: 4.454 ± 2.141
3.341AspPro: 3.341 ± 1.606
1.114AspGln: 1.114 ± 0.535
2.227AspArg: 2.227 ± 6.13
4.454AspSer: 4.454 ± 2.141
2.227AspThr: 2.227 ± 1.071
4.454AspVal: 4.454 ± 2.141
0.0AspTrp: 0.0 ± 0.0
5.568AspTyr: 5.568 ± 0.924
0.0AspXaa: 0.0 ± 0.0
Glu
1.114GluAla: 1.114 ± 0.535
1.114GluCys: 1.114 ± 0.535
3.341GluAsp: 3.341 ± 1.606
2.227GluGlu: 2.227 ± 2.53
0.0GluPhe: 0.0 ± 0.0
4.454GluGly: 4.454 ± 1.459
1.114GluHis: 1.114 ± 0.535
0.0GluIle: 0.0 ± 0.0
2.227GluLys: 2.227 ± 1.071
2.227GluLeu: 2.227 ± 2.53
0.0GluMet: 0.0 ± 1.618
1.114GluAsn: 1.114 ± 0.535
0.0GluPro: 0.0 ± 0.0
3.341GluGln: 3.341 ± 1.995
2.227GluArg: 2.227 ± 2.53
2.227GluSer: 2.227 ± 2.53
2.227GluThr: 2.227 ± 1.071
0.0GluVal: 0.0 ± 0.0
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
3.341PheAla: 3.341 ± 1.995
1.114PheCys: 1.114 ± 3.065
0.0PheAsp: 0.0 ± 0.0
1.114PheGlu: 1.114 ± 3.065
0.0PhePhe: 0.0 ± 0.0
5.568PheGly: 5.568 ± 2.676
1.114PheHis: 1.114 ± 0.535
3.341PheIle: 3.341 ± 1.995
3.341PheLys: 3.341 ± 1.606
3.341PheLeu: 3.341 ± 1.606
2.227PheMet: 2.227 ± 1.071
3.341PheAsn: 3.341 ± 1.606
2.227PhePro: 2.227 ± 2.53
1.114PheGln: 1.114 ± 0.535
3.341PheArg: 3.341 ± 1.995
3.341PheSer: 3.341 ± 1.606
2.227PheThr: 2.227 ± 1.071
0.0PheVal: 0.0 ± 0.0
1.114PheTrp: 1.114 ± 3.065
1.114PheTyr: 1.114 ± 0.535
0.0PheXaa: 0.0 ± 0.0
Gly
5.568GlyAla: 5.568 ± 11.726
2.227GlyCys: 2.227 ± 2.53
7.795GlyAsp: 7.795 ± 7.055
2.227GlyGlu: 2.227 ± 2.53
1.114GlyPhe: 1.114 ± 0.535
15.59GlyGly: 15.59 ± 17.71
1.114GlyHis: 1.114 ± 3.065
1.114GlyIle: 1.114 ± 0.535
5.568GlyLys: 5.568 ± 2.676
1.114GlyLeu: 1.114 ± 0.535
3.341GlyMet: 3.341 ± 1.606
4.454GlyAsn: 4.454 ± 1.459
6.682GlyPro: 6.682 ± 11.19
2.227GlyGln: 2.227 ± 2.53
7.795GlyArg: 7.795 ± 0.146
5.568GlySer: 5.568 ± 2.676
2.227GlyThr: 2.227 ± 1.071
0.0GlyVal: 0.0 ± 0.0
1.114GlyTrp: 1.114 ± 0.535
4.454GlyTyr: 4.454 ± 2.141
0.0GlyXaa: 0.0 ± 0.0
His
1.114HisAla: 1.114 ± 3.065
0.0HisCys: 0.0 ± 0.0
1.114HisAsp: 1.114 ± 0.535
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
1.114HisGly: 1.114 ± 0.535
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
1.114HisLys: 1.114 ± 0.535
2.227HisLeu: 2.227 ± 2.53
2.227HisMet: 2.227 ± 1.071
2.227HisAsn: 2.227 ± 2.53
5.568HisPro: 5.568 ± 0.924
0.0HisGln: 0.0 ± 0.0
1.114HisArg: 1.114 ± 0.535
0.0HisSer: 0.0 ± 0.0
3.341HisThr: 3.341 ± 1.606
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.114HisTyr: 1.114 ± 0.535
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
0.0IleCys: 0.0 ± 0.0
1.114IleAsp: 1.114 ± 0.535
0.0IleGlu: 0.0 ± 0.0
0.0IlePhe: 0.0 ± 0.0
1.114IleGly: 1.114 ± 3.065
0.0IleHis: 0.0 ± 0.0
1.114IleIle: 1.114 ± 0.535
2.227IleLys: 2.227 ± 1.071
1.114IleLeu: 1.114 ± 0.535
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
2.227IlePro: 2.227 ± 1.071
2.227IleGln: 2.227 ± 1.071
5.568IleArg: 5.568 ± 2.676
1.114IleSer: 1.114 ± 0.535
1.114IleThr: 1.114 ± 0.535
3.341IleVal: 3.341 ± 1.606
0.0IleTrp: 0.0 ± 0.0
1.114IleTyr: 1.114 ± 0.535
0.0IleXaa: 0.0 ± 0.0
Lys
1.114LysAla: 1.114 ± 0.535
3.341LysCys: 3.341 ± 1.606
2.227LysAsp: 2.227 ± 1.071
3.341LysGlu: 3.341 ± 1.606
1.114LysPhe: 1.114 ± 0.535
2.227LysGly: 2.227 ± 1.071
0.0LysHis: 0.0 ± 0.0
2.227LysIle: 2.227 ± 1.071
5.568LysLys: 5.568 ± 2.676
6.682LysLeu: 6.682 ± 3.212
0.0LysMet: 0.0 ± 0.0
4.454LysAsn: 4.454 ± 2.141
1.114LysPro: 1.114 ± 0.535
1.114LysGln: 1.114 ± 0.535
2.227LysArg: 2.227 ± 1.071
3.341LysSer: 3.341 ± 1.606
5.568LysThr: 5.568 ± 2.676
3.341LysVal: 3.341 ± 1.606
3.341LysTrp: 3.341 ± 1.606
6.682LysTyr: 6.682 ± 3.212
0.0LysXaa: 0.0 ± 0.0
Leu
5.568LeuAla: 5.568 ± 0.924
2.227LeuCys: 2.227 ± 1.071
3.341LeuAsp: 3.341 ± 1.606
2.227LeuGlu: 2.227 ± 2.53
4.454LeuPhe: 4.454 ± 2.141
2.227LeuGly: 2.227 ± 1.071
3.341LeuHis: 3.341 ± 1.606
2.227LeuIle: 2.227 ± 1.071
1.114LeuLys: 1.114 ± 0.535
6.682LeuLeu: 6.682 ± 3.212
1.114LeuMet: 1.114 ± 0.535
2.227LeuAsn: 2.227 ± 2.53
6.682LeuPro: 6.682 ± 7.59
1.114LeuGln: 1.114 ± 0.535
4.454LeuArg: 4.454 ± 2.141
2.227LeuSer: 2.227 ± 1.071
6.682LeuThr: 6.682 ± 3.212
3.341LeuVal: 3.341 ± 1.606
2.227LeuTrp: 2.227 ± 1.071
5.568LeuTyr: 5.568 ± 2.676
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
1.114MetAsp: 1.114 ± 0.535
0.0MetGlu: 0.0 ± 0.0
1.114MetPhe: 1.114 ± 0.535
1.114MetGly: 1.114 ± 0.535
1.114MetHis: 1.114 ± 0.535
0.0MetIle: 0.0 ± 0.0
1.114MetLys: 1.114 ± 0.535
2.227MetLeu: 2.227 ± 1.071
1.114MetMet: 1.114 ± 0.535
0.0MetAsn: 0.0 ± 0.0
2.227MetPro: 2.227 ± 1.071
0.0MetGln: 0.0 ± 0.0
1.114MetArg: 1.114 ± 0.535
2.227MetSer: 2.227 ± 2.53
1.114MetThr: 1.114 ± 0.535
2.227MetVal: 2.227 ± 1.071
1.114MetTrp: 1.114 ± 0.535
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.227AsnAla: 2.227 ± 1.071
0.0AsnCys: 0.0 ± 0.0
3.341AsnAsp: 3.341 ± 1.606
1.114AsnGlu: 1.114 ± 0.535
2.227AsnPhe: 2.227 ± 2.53
1.114AsnGly: 1.114 ± 0.535
2.227AsnHis: 2.227 ± 2.53
4.454AsnIle: 4.454 ± 2.141
6.682AsnLys: 6.682 ± 3.212
3.341AsnLeu: 3.341 ± 1.995
0.0AsnMet: 0.0 ± 0.0
2.227AsnAsn: 2.227 ± 2.53
6.682AsnPro: 6.682 ± 3.212
1.114AsnGln: 1.114 ± 0.535
1.114AsnArg: 1.114 ± 0.535
2.227AsnSer: 2.227 ± 1.071
3.341AsnThr: 3.341 ± 1.606
1.114AsnVal: 1.114 ± 3.065
1.114AsnTrp: 1.114 ± 3.065
1.114AsnTyr: 1.114 ± 0.535
0.0AsnXaa: 0.0 ± 0.0
Pro
5.568ProAla: 5.568 ± 4.525
4.454ProCys: 4.454 ± 1.459
1.114ProAsp: 1.114 ± 0.535
2.227ProGlu: 2.227 ± 2.53
3.341ProPhe: 3.341 ± 1.995
7.795ProGly: 7.795 ± 7.055
2.227ProHis: 2.227 ± 1.071
2.227ProIle: 2.227 ± 1.071
5.568ProLys: 5.568 ± 2.676
5.568ProLeu: 5.568 ± 0.924
1.114ProMet: 1.114 ± 0.535
0.0ProAsn: 0.0 ± 0.0
12.249ProPro: 12.249 ± 19.315
3.341ProGln: 3.341 ± 1.995
6.682ProArg: 6.682 ± 0.389
4.454ProSer: 4.454 ± 1.459
4.454ProThr: 4.454 ± 1.459
3.341ProVal: 3.341 ± 5.595
2.227ProTrp: 2.227 ± 1.071
1.114ProTyr: 1.114 ± 0.535
0.0ProXaa: 0.0 ± 0.0
Gln
2.227GlnAla: 2.227 ± 2.53
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
1.114GlnGlu: 1.114 ± 3.065
1.114GlnPhe: 1.114 ± 0.535
0.0GlnGly: 0.0 ± 0.0
0.0GlnHis: 0.0 ± 0.0
1.114GlnIle: 1.114 ± 0.535
1.114GlnLys: 1.114 ± 0.535
2.227GlnLeu: 2.227 ± 1.071
2.227GlnMet: 2.227 ± 1.071
2.227GlnAsn: 2.227 ± 1.071
1.114GlnPro: 1.114 ± 3.065
1.114GlnGln: 1.114 ± 0.535
2.227GlnArg: 2.227 ± 1.071
2.227GlnSer: 2.227 ± 1.071
2.227GlnThr: 2.227 ± 1.071
5.568GlnVal: 5.568 ± 2.676
2.227GlnTrp: 2.227 ± 1.071
4.454GlnTyr: 4.454 ± 2.141
0.0GlnXaa: 0.0 ± 0.0
Arg
10.022ArgAla: 10.022 ± 1.217
1.114ArgCys: 1.114 ± 0.535
8.909ArgAsp: 8.909 ± 0.682
0.0ArgGlu: 0.0 ± 0.0
3.341ArgPhe: 3.341 ± 1.606
6.682ArgGly: 6.682 ± 3.989
1.114ArgHis: 1.114 ± 0.535
1.114ArgIle: 1.114 ± 0.535
5.568ArgLys: 5.568 ± 2.676
0.0ArgLeu: 0.0 ± 0.0
0.0ArgMet: 0.0 ± 0.0
3.341ArgAsn: 3.341 ± 1.995
7.795ArgPro: 7.795 ± 3.454
1.114ArgGln: 1.114 ± 0.535
33.408ArgArg: 33.408 ± 16.058
7.795ArgSer: 7.795 ± 0.146
4.454ArgThr: 4.454 ± 2.141
2.227ArgVal: 2.227 ± 1.071
7.795ArgTrp: 7.795 ± 3.747
3.341ArgTyr: 3.341 ± 1.995
0.0ArgXaa: 0.0 ± 0.0
Ser
0.0SerAla: 0.0 ± 0.0
2.227SerCys: 2.227 ± 2.53
3.341SerAsp: 3.341 ± 1.606
1.114SerGlu: 1.114 ± 0.535
3.341SerPhe: 3.341 ± 1.995
7.795SerGly: 7.795 ± 3.747
2.227SerHis: 2.227 ± 2.53
0.0SerIle: 0.0 ± 0.0
3.341SerLys: 3.341 ± 1.606
3.341SerLeu: 3.341 ± 1.606
0.0SerMet: 0.0 ± 0.0
3.341SerAsn: 3.341 ± 1.606
7.795SerPro: 7.795 ± 3.747
3.341SerGln: 3.341 ± 1.606
4.454SerArg: 4.454 ± 1.459
10.022SerSer: 10.022 ± 4.817
1.114SerThr: 1.114 ± 0.535
2.227SerVal: 2.227 ± 1.071
2.227SerTrp: 2.227 ± 1.071
2.227SerTyr: 2.227 ± 1.071
0.0SerXaa: 0.0 ± 0.0
Thr
4.454ThrAla: 4.454 ± 2.141
0.0ThrCys: 0.0 ± 0.0
4.454ThrAsp: 4.454 ± 2.141
1.114ThrGlu: 1.114 ± 0.535
7.795ThrPhe: 7.795 ± 3.747
1.114ThrGly: 1.114 ± 0.535
1.114ThrHis: 1.114 ± 0.535
0.0ThrIle: 0.0 ± 0.0
4.454ThrLys: 4.454 ± 2.141
4.454ThrLeu: 4.454 ± 2.141
1.114ThrMet: 1.114 ± 0.495
2.227ThrAsn: 2.227 ± 1.071
5.568ThrPro: 5.568 ± 2.676
1.114ThrGln: 1.114 ± 0.535
5.568ThrArg: 5.568 ± 2.676
1.114ThrSer: 1.114 ± 0.535
5.568ThrThr: 5.568 ± 2.676
5.568ThrVal: 5.568 ± 0.924
0.0ThrTrp: 0.0 ± 0.0
1.114ThrTyr: 1.114 ± 0.535
0.0ThrXaa: 0.0 ± 0.0
Val
5.568ValAla: 5.568 ± 8.125
1.114ValCys: 1.114 ± 0.535
3.341ValAsp: 3.341 ± 1.606
2.227ValGlu: 2.227 ± 1.071
3.341ValPhe: 3.341 ± 1.606
1.114ValGly: 1.114 ± 0.535
1.114ValHis: 1.114 ± 3.065
1.114ValIle: 1.114 ± 0.535
3.341ValLys: 3.341 ± 1.606
3.341ValLeu: 3.341 ± 1.606
1.114ValMet: 1.114 ± 0.535
1.114ValAsn: 1.114 ± 0.535
1.114ValPro: 1.114 ± 3.065
2.227ValGln: 2.227 ± 1.071
5.568ValArg: 5.568 ± 0.924
1.114ValSer: 1.114 ± 0.535
3.341ValThr: 3.341 ± 1.606
4.454ValVal: 4.454 ± 2.141
1.114ValTrp: 1.114 ± 0.535
2.227ValTyr: 2.227 ± 1.071
0.0ValXaa: 0.0 ± 0.0
Trp
1.114TrpAla: 1.114 ± 0.535
1.114TrpCys: 1.114 ± 0.535
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
2.227TrpPhe: 2.227 ± 6.13
4.454TrpGly: 4.454 ± 2.141
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
1.114TrpMet: 1.114 ± 0.535
1.114TrpAsn: 1.114 ± 0.535
0.0TrpPro: 0.0 ± 0.0
1.114TrpGln: 1.114 ± 0.535
5.568TrpArg: 5.568 ± 2.676
4.454TrpSer: 4.454 ± 2.141
1.114TrpThr: 1.114 ± 0.535
1.114TrpVal: 1.114 ± 0.535
1.114TrpTrp: 1.114 ± 0.535
2.227TrpTyr: 2.227 ± 1.071
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.341TyrAla: 3.341 ± 1.606
0.0TyrCys: 0.0 ± 0.0
3.341TyrAsp: 3.341 ± 1.606
1.114TyrGlu: 1.114 ± 0.535
2.227TyrPhe: 2.227 ± 1.071
3.341TyrGly: 3.341 ± 1.995
3.341TyrHis: 3.341 ± 1.606
2.227TyrIle: 2.227 ± 1.071
3.341TyrLys: 3.341 ± 1.606
1.114TyrLeu: 1.114 ± 0.535
1.114TyrMet: 1.114 ± 0.535
7.795TyrAsn: 7.795 ± 0.146
1.114TyrPro: 1.114 ± 0.535
2.227TyrGln: 2.227 ± 1.071
4.454TyrArg: 4.454 ± 2.141
1.114TyrSer: 1.114 ± 0.535
4.454TyrThr: 4.454 ± 2.141
1.114TyrVal: 1.114 ± 0.535
1.114TyrTrp: 1.114 ± 0.535
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (899 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski