Amino acid dipepetide frequency for Trametes versicolor (strain FP-101664) (White-rot fungus) (Coriolus versicolor)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.184AlaAla: 11.184 ± 0.285
1.269AlaCys: 1.269 ± 0.061
5.347AlaAsp: 5.347 ± 0.141
5.389AlaGlu: 5.389 ± 0.152
3.492AlaPhe: 3.492 ± 0.114
6.065AlaGly: 6.065 ± 0.158
2.829AlaHis: 2.829 ± 0.098
4.029AlaIle: 4.029 ± 0.104
3.767AlaLys: 3.767 ± 0.118
9.501AlaLeu: 9.501 ± 0.19
2.181AlaMet: 2.181 ± 0.079
2.521AlaAsn: 2.521 ± 0.098
6.772AlaPro: 6.772 ± 0.207
3.909AlaGln: 3.909 ± 0.118
7.069AlaArg: 7.069 ± 0.187
7.798AlaSer: 7.798 ± 0.178
5.834AlaThr: 5.834 ± 0.151
6.073AlaVal: 6.073 ± 0.145
1.424AlaTrp: 1.424 ± 0.065
2.482AlaTyr: 2.482 ± 0.09
0.0AlaXaa: 0.0 ± 0.0
Cys
1.344CysAla: 1.344 ± 0.059
0.287CysCys: 0.287 ± 0.027
0.69CysAsp: 0.69 ± 0.052
0.637CysGlu: 0.637 ± 0.045
0.556CysPhe: 0.556 ± 0.044
0.971CysGly: 0.971 ± 0.058
0.312CysHis: 0.312 ± 0.03
0.662CysIle: 0.662 ± 0.049
0.568CysLys: 0.568 ± 0.044
1.202CysLeu: 1.202 ± 0.054
0.309CysMet: 0.309 ± 0.028
0.387CysAsn: 0.387 ± 0.033
0.849CysPro: 0.849 ± 0.057
0.476CysGln: 0.476 ± 0.035
0.938CysArg: 0.938 ± 0.053
0.988CysSer: 0.988 ± 0.056
0.807CysThr: 0.807 ± 0.054
0.915CysVal: 0.915 ± 0.049
0.159CysTrp: 0.159 ± 0.021
0.351CysTyr: 0.351 ± 0.033
0.0CysXaa: 0.0 ± 0.0
Asp
6.296AspAla: 6.296 ± 0.158
0.721AspCys: 0.721 ± 0.05
4.688AspAsp: 4.688 ± 0.162
4.365AspGlu: 4.365 ± 0.15
2.081AspPhe: 2.081 ± 0.07
4.457AspGly: 4.457 ± 0.113
1.363AspHis: 1.363 ± 0.071
2.916AspIle: 2.916 ± 0.095
2.023AspLys: 2.023 ± 0.087
4.93AspLeu: 4.93 ± 0.126
1.324AspMet: 1.324 ± 0.061
1.516AspAsn: 1.516 ± 0.075
3.937AspPro: 3.937 ± 0.115
1.628AspGln: 1.628 ± 0.066
3.085AspArg: 3.085 ± 0.101
4.048AspSer: 4.048 ± 0.136
3.361AspThr: 3.361 ± 0.102
4.56AspVal: 4.56 ± 0.139
0.874AspTrp: 0.874 ± 0.048
1.424AspTyr: 1.424 ± 0.061
0.0AspXaa: 0.0 ± 0.0
Glu
5.189GluAla: 5.189 ± 0.131
0.723GluCys: 0.723 ± 0.048
4.705GluAsp: 4.705 ± 0.142
5.036GluGlu: 5.036 ± 0.166
1.917GluPhe: 1.917 ± 0.078
3.653GluGly: 3.653 ± 0.107
1.714GluHis: 1.714 ± 0.058
2.515GluIle: 2.515 ± 0.083
2.568GluLys: 2.568 ± 0.109
5.709GluLeu: 5.709 ± 0.156
1.269GluMet: 1.269 ± 0.06
1.87GluAsn: 1.87 ± 0.079
2.757GluPro: 2.757 ± 0.097
2.162GluGln: 2.162 ± 0.085
4.463GluArg: 4.463 ± 0.13
3.489GluSer: 3.489 ± 0.11
3.105GluThr: 3.105 ± 0.093
3.664GluVal: 3.664 ± 0.1
1.138GluTrp: 1.138 ± 0.061
1.516GluTyr: 1.516 ± 0.067
0.0GluXaa: 0.0 ± 0.0
Phe
3.525PheAla: 3.525 ± 0.107
0.593PheCys: 0.593 ± 0.048
2.178PheAsp: 2.178 ± 0.079
1.981PheGlu: 1.981 ± 0.082
1.302PhePhe: 1.302 ± 0.071
2.515PheGly: 2.515 ± 0.092
0.885PheHis: 0.885 ± 0.049
1.527PheIle: 1.527 ± 0.067
1.344PheLys: 1.344 ± 0.061
3.302PheLeu: 3.302 ± 0.099
0.746PheMet: 0.746 ± 0.048
1.068PheAsn: 1.068 ± 0.066
2.098PhePro: 2.098 ± 0.086
1.13PheGln: 1.13 ± 0.059
2.075PheArg: 2.075 ± 0.075
2.682PheSer: 2.682 ± 0.094
2.017PheThr: 2.017 ± 0.068
2.551PheVal: 2.551 ± 0.096
0.659PheTrp: 0.659 ± 0.042
1.024PheTyr: 1.024 ± 0.064
0.0PheXaa: 0.0 ± 0.0
Gly
5.909GlyAla: 5.909 ± 0.166
0.904GlyCys: 0.904 ± 0.052
3.608GlyAsp: 3.608 ± 0.105
3.633GlyGlu: 3.633 ± 0.099
2.493GlyPhe: 2.493 ± 0.085
5.194GlyGly: 5.194 ± 0.165
1.772GlyHis: 1.772 ± 0.082
2.893GlyIle: 2.893 ± 0.1
2.921GlyLys: 2.921 ± 0.105
5.414GlyLeu: 5.414 ± 0.135
1.422GlyMet: 1.422 ± 0.073
1.845GlyAsn: 1.845 ± 0.084
3.753GlyPro: 3.753 ± 0.135
2.306GlyGln: 2.306 ± 0.091
4.301GlyArg: 4.301 ± 0.114
4.949GlySer: 4.949 ± 0.148
4.037GlyThr: 4.037 ± 0.108
4.499GlyVal: 4.499 ± 0.122
1.138GlyTrp: 1.138 ± 0.055
1.705GlyTyr: 1.705 ± 0.088
0.0GlyXaa: 0.0 ± 0.0
His
2.754HisAla: 2.754 ± 0.084
0.431HisCys: 0.431 ± 0.031
1.533HisAsp: 1.533 ± 0.081
1.338HisGlu: 1.338 ± 0.054
0.896HisPhe: 0.896 ± 0.05
1.808HisGly: 1.808 ± 0.071
0.896HisHis: 0.896 ± 0.054
1.33HisIle: 1.33 ± 0.06
0.938HisLys: 0.938 ± 0.046
2.66HisLeu: 2.66 ± 0.103
0.57HisMet: 0.57 ± 0.039
0.812HisAsn: 0.812 ± 0.05
2.084HisPro: 2.084 ± 0.074
0.854HisGln: 0.854 ± 0.053
1.867HisArg: 1.867 ± 0.075
1.922HisSer: 1.922 ± 0.081
1.641HisThr: 1.641 ± 0.072
1.872HisVal: 1.872 ± 0.079
0.428HisTrp: 0.428 ± 0.04
0.782HisTyr: 0.782 ± 0.049
0.0HisXaa: 0.0 ± 0.0
Ile
4.357IleAla: 4.357 ± 0.116
0.648IleCys: 0.648 ± 0.047
2.688IleAsp: 2.688 ± 0.096
2.457IleGlu: 2.457 ± 0.092
1.552IlePhe: 1.552 ± 0.07
2.64IleGly: 2.64 ± 0.115
1.099IleHis: 1.099 ± 0.059
1.942IleIle: 1.942 ± 0.084
1.577IleLys: 1.577 ± 0.075
3.939IleLeu: 3.939 ± 0.108
0.81IleMet: 0.81 ± 0.055
1.433IleAsn: 1.433 ± 0.065
3.183IlePro: 3.183 ± 0.1
1.452IleGln: 1.452 ± 0.058
2.746IleArg: 2.746 ± 0.094
3.252IleSer: 3.252 ± 0.1
2.596IleThr: 2.596 ± 0.093
3.083IleVal: 3.083 ± 0.1
0.612IleTrp: 0.612 ± 0.044
1.163IleTyr: 1.163 ± 0.057
0.0IleXaa: 0.0 ± 0.0
Lys
3.761LysAla: 3.761 ± 0.125
0.47LysCys: 0.47 ± 0.036
2.203LysAsp: 2.203 ± 0.098
2.607LysGlu: 2.607 ± 0.096
1.021LysPhe: 1.021 ± 0.048
2.509LysGly: 2.509 ± 0.113
1.155LysHis: 1.155 ± 0.065
1.711LysIle: 1.711 ± 0.083
2.473LysLys: 2.473 ± 0.102
3.455LysLeu: 3.455 ± 0.123
0.776LysMet: 0.776 ± 0.046
1.308LysAsn: 1.308 ± 0.065
2.24LysPro: 2.24 ± 0.088
1.424LysGln: 1.424 ± 0.07
3.102LysArg: 3.102 ± 0.107
2.476LysSer: 2.476 ± 0.104
2.359LysThr: 2.359 ± 0.09
2.345LysVal: 2.345 ± 0.09
0.559LysTrp: 0.559 ± 0.045
1.085LysTyr: 1.085 ± 0.057
0.0LysXaa: 0.0 ± 0.0
Leu
8.858LeuAla: 8.858 ± 0.176
1.271LeuCys: 1.271 ± 0.065
5.417LeuAsp: 5.417 ± 0.128
5.361LeuGlu: 5.361 ± 0.156
3.18LeuPhe: 3.18 ± 0.088
5.325LeuGly: 5.325 ± 0.132
2.607LeuHis: 2.607 ± 0.094
3.467LeuIle: 3.467 ± 0.102
3.322LeuLys: 3.322 ± 0.11
8.266LeuLeu: 8.266 ± 0.183
1.697LeuMet: 1.697 ± 0.067
2.557LeuAsn: 2.557 ± 0.089
6.432LeuPro: 6.432 ± 0.143
3.781LeuGln: 3.781 ± 0.136
6.802LeuArg: 6.802 ± 0.169
7.189LeuSer: 7.189 ± 0.159
5.194LeuThr: 5.194 ± 0.135
5.753LeuVal: 5.753 ± 0.157
1.43LeuTrp: 1.43 ± 0.064
2.306LeuTyr: 2.306 ± 0.087
0.0LeuXaa: 0.0 ± 0.0
Met
1.917MetAla: 1.917 ± 0.073
0.317MetCys: 0.317 ± 0.027
1.333MetAsp: 1.333 ± 0.058
1.124MetGlu: 1.124 ± 0.058
0.729MetPhe: 0.729 ± 0.054
1.26MetGly: 1.26 ± 0.057
0.576MetHis: 0.576 ± 0.035
0.754MetIle: 0.754 ± 0.047
0.824MetLys: 0.824 ± 0.053
1.783MetLeu: 1.783 ± 0.075
0.453MetMet: 0.453 ± 0.039
0.684MetAsn: 0.684 ± 0.04
1.424MetPro: 1.424 ± 0.068
0.818MetGln: 0.818 ± 0.05
1.527MetArg: 1.527 ± 0.067
1.97MetSer: 1.97 ± 0.067
1.029MetThr: 1.029 ± 0.063
1.216MetVal: 1.216 ± 0.061
0.306MetTrp: 0.306 ± 0.027
0.593MetTyr: 0.593 ± 0.045
0.0MetXaa: 0.0 ± 0.0
Asn
3.127AsnAla: 3.127 ± 0.082
0.426AsnCys: 0.426 ± 0.038
1.555AsnAsp: 1.555 ± 0.071
1.463AsnGlu: 1.463 ± 0.058
1.143AsnPhe: 1.143 ± 0.062
2.262AsnGly: 2.262 ± 0.097
0.734AsnHis: 0.734 ± 0.048
1.628AsnIle: 1.628 ± 0.068
1.043AsnLys: 1.043 ± 0.053
2.707AsnLeu: 2.707 ± 0.087
0.726AsnMet: 0.726 ± 0.045
0.938AsnAsn: 0.938 ± 0.071
1.964AsnPro: 1.964 ± 0.072
0.913AsnGln: 0.913 ± 0.055
1.525AsnArg: 1.525 ± 0.061
1.922AsnSer: 1.922 ± 0.08
1.953AsnThr: 1.953 ± 0.075
2.028AsnVal: 2.028 ± 0.081
0.378AsnTrp: 0.378 ± 0.034
0.79AsnTyr: 0.79 ± 0.046
0.0AsnXaa: 0.0 ± 0.0
Pro
6.958ProAla: 6.958 ± 0.18
0.615ProCys: 0.615 ± 0.043
3.578ProAsp: 3.578 ± 0.108
4.198ProGlu: 4.198 ± 0.111
2.37ProPhe: 2.37 ± 0.086
4.129ProGly: 4.129 ± 0.151
1.87ProHis: 1.87 ± 0.079
2.635ProIle: 2.635 ± 0.102
2.331ProLys: 2.331 ± 0.099
5.467ProLeu: 5.467 ± 0.13
1.155ProMet: 1.155 ± 0.067
1.984ProAsn: 1.984 ± 0.077
7.264ProPro: 7.264 ± 0.35
2.437ProGln: 2.437 ± 0.106
4.571ProArg: 4.571 ± 0.149
6.627ProSer: 6.627 ± 0.183
4.323ProThr: 4.323 ± 0.13
4.042ProVal: 4.042 ± 0.121
0.851ProTrp: 0.851 ± 0.054
1.719ProTyr: 1.719 ± 0.07
0.0ProXaa: 0.0 ± 0.0
Gln
3.62GlnAla: 3.62 ± 0.104
0.548GlnCys: 0.548 ± 0.043
2.126GlnAsp: 2.126 ± 0.078
2.145GlnGlu: 2.145 ± 0.089
1.207GlnPhe: 1.207 ± 0.053
2.217GlnGly: 2.217 ± 0.075
1.085GlnHis: 1.085 ± 0.055
1.366GlnIle: 1.366 ± 0.064
1.377GlnLys: 1.377 ± 0.062
3.16GlnLeu: 3.16 ± 0.1
0.793GlnMet: 0.793 ± 0.049
0.999GlnAsn: 0.999 ± 0.056
2.42GlnPro: 2.42 ± 0.099
1.717GlnGln: 1.717 ± 0.104
2.671GlnArg: 2.671 ± 0.081
2.685GlnSer: 2.685 ± 0.09
2.139GlnThr: 2.139 ± 0.089
2.092GlnVal: 2.092 ± 0.07
0.551GlnTrp: 0.551 ± 0.038
1.007GlnTyr: 1.007 ± 0.058
0.0GlnXaa: 0.0 ± 0.0
Arg
7.078ArgAla: 7.078 ± 0.196
0.924ArgCys: 0.924 ± 0.054
3.909ArgAsp: 3.909 ± 0.12
4.229ArgGlu: 4.229 ± 0.123
2.376ArgPhe: 2.376 ± 0.083
3.99ArgGly: 3.99 ± 0.125
1.739ArgHis: 1.739 ± 0.08
3.094ArgIle: 3.094 ± 0.093
2.969ArgLys: 2.969 ± 0.1
6.126ArgLeu: 6.126 ± 0.16
1.55ArgMet: 1.55 ± 0.064
1.995ArgAsn: 1.995 ± 0.078
4.432ArgPro: 4.432 ± 0.145
2.326ArgGln: 2.326 ± 0.094
6.302ArgArg: 6.302 ± 0.187
4.908ArgSer: 4.908 ± 0.127
4.093ArgThr: 4.093 ± 0.119
4.315ArgVal: 4.315 ± 0.118
1.146ArgTrp: 1.146 ± 0.056
1.842ArgTyr: 1.842 ± 0.08
0.0ArgXaa: 0.0 ± 0.0
Ser
7.94SerAla: 7.94 ± 0.164
0.99SerCys: 0.99 ± 0.055
4.415SerAsp: 4.415 ± 0.146
3.862SerGlu: 3.862 ± 0.115
2.426SerPhe: 2.426 ± 0.085
5.072SerGly: 5.072 ± 0.132
2.039SerHis: 2.039 ± 0.086
3.288SerIle: 3.288 ± 0.097
2.682SerLys: 2.682 ± 0.084
6.524SerLeu: 6.524 ± 0.166
1.647SerMet: 1.647 ± 0.065
2.217SerAsn: 2.217 ± 0.088
5.854SerPro: 5.854 ± 0.19
2.765SerGln: 2.765 ± 0.091
5.086SerArg: 5.086 ± 0.136
8.088SerSer: 8.088 ± 0.291
5.842SerThr: 5.842 ± 0.157
4.685SerVal: 4.685 ± 0.129
0.979SerTrp: 0.979 ± 0.06
1.63SerTyr: 1.63 ± 0.069
0.0SerXaa: 0.0 ± 0.0
Thr
5.523ThrAla: 5.523 ± 0.143
0.704ThrCys: 0.704 ± 0.049
2.849ThrAsp: 2.849 ± 0.102
2.913ThrGlu: 2.913 ± 0.093
2.354ThrPhe: 2.354 ± 0.075
4.059ThrGly: 4.059 ± 0.121
1.708ThrHis: 1.708 ± 0.07
2.866ThrIle: 2.866 ± 0.099
2.006ThrLys: 2.006 ± 0.07
5.904ThrLeu: 5.904 ± 0.143
1.113ThrMet: 1.113 ± 0.057
1.641ThrAsn: 1.641 ± 0.073
4.732ThrPro: 4.732 ± 0.141
2.048ThrGln: 2.048 ± 0.078
3.862ThrArg: 3.862 ± 0.134
5.603ThrSer: 5.603 ± 0.166
4.123ThrThr: 4.123 ± 0.158
3.731ThrVal: 3.731 ± 0.107
0.932ThrTrp: 0.932 ± 0.057
1.625ThrTyr: 1.625 ± 0.076
0.0ThrXaa: 0.0 ± 0.0
Val
5.959ValAla: 5.959 ± 0.136
0.949ValCys: 0.949 ± 0.05
4.079ValAsp: 4.079 ± 0.109
3.951ValGlu: 3.951 ± 0.117
2.487ValPhe: 2.487 ± 0.09
3.834ValGly: 3.834 ± 0.132
1.839ValHis: 1.839 ± 0.064
2.729ValIle: 2.729 ± 0.098
2.546ValLys: 2.546 ± 0.1
6.268ValLeu: 6.268 ± 0.145
1.283ValMet: 1.283 ± 0.058
1.959ValAsn: 1.959 ± 0.078
4.627ValPro: 4.627 ± 0.109
2.356ValGln: 2.356 ± 0.078
4.465ValArg: 4.465 ± 0.133
4.691ValSer: 4.691 ± 0.123
3.272ValThr: 3.272 ± 0.101
4.76ValVal: 4.76 ± 0.133
1.066ValTrp: 1.066 ± 0.06
1.778ValTyr: 1.778 ± 0.069
0.0ValXaa: 0.0 ± 0.0
Trp
1.299TrpAla: 1.299 ± 0.062
0.259TrpCys: 0.259 ± 0.028
1.054TrpAsp: 1.054 ± 0.074
0.946TrpGlu: 0.946 ± 0.056
0.581TrpPhe: 0.581 ± 0.038
0.84TrpGly: 0.84 ± 0.047
0.481TrpHis: 0.481 ± 0.037
0.565TrpIle: 0.565 ± 0.039
0.765TrpLys: 0.765 ± 0.048
1.408TrpLeu: 1.408 ± 0.081
0.326TrpMet: 0.326 ± 0.034
0.648TrpAsn: 0.648 ± 0.045
0.734TrpPro: 0.734 ± 0.052
0.534TrpGln: 0.534 ± 0.04
1.174TrpArg: 1.174 ± 0.056
0.954TrpSer: 0.954 ± 0.052
1.007TrpThr: 1.007 ± 0.055
0.868TrpVal: 0.868 ± 0.05
0.32TrpTrp: 0.32 ± 0.028
0.581TrpTyr: 0.581 ± 0.04
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.337TyrAla: 2.337 ± 0.074
0.356TyrCys: 0.356 ± 0.031
1.641TyrAsp: 1.641 ± 0.066
1.525TyrGlu: 1.525 ± 0.071
1.038TyrPhe: 1.038 ± 0.058
1.9TyrGly: 1.9 ± 0.083
0.715TyrHis: 0.715 ± 0.043
1.313TyrIle: 1.313 ± 0.078
0.999TyrLys: 0.999 ± 0.055
2.49TyrLeu: 2.49 ± 0.087
0.487TyrMet: 0.487 ± 0.036
0.846TyrAsn: 0.846 ± 0.05
1.569TyrPro: 1.569 ± 0.07
0.89TyrGln: 0.89 ± 0.052
1.708TyrArg: 1.708 ± 0.076
1.792TyrSer: 1.792 ± 0.083
1.561TyrThr: 1.561 ± 0.077
1.842TyrVal: 1.842 ± 0.071
0.395TyrTrp: 0.395 ± 0.036
0.874TyrTyr: 0.874 ± 0.053
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1022 proteins (359438 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski