Human papillomavirus 133

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; Gammapapillomavirus 10

Average proteome isoelectric point is 6.29

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|E7BQA2|E7BQA2_9PAPI Replication protein E1 OS=Human papillomavirus 133 OX=909332 GN=E1 PE=3 SV=1
MM1 pKa = 7.75IGPEE5 pKa = 4.0IEE7 pKa = 4.13VGDD10 pKa = 4.46IEE12 pKa = 4.81LQLEE16 pKa = 4.34QLVMPANLLSDD27 pKa = 4.08EE28 pKa = 4.32VLSPDD33 pKa = 3.36EE34 pKa = 4.99DD35 pKa = 3.97EE36 pKa = 5.3EE37 pKa = 4.69EE38 pKa = 4.18EE39 pKa = 5.17LPVEE43 pKa = 4.8PYY45 pKa = 10.57RR46 pKa = 11.84IDD48 pKa = 3.77SRR50 pKa = 11.84CKK52 pKa = 8.12VCNSAVRR59 pKa = 11.84LFVAASHH66 pKa = 5.38QGIRR70 pKa = 11.84EE71 pKa = 4.09LQQLLFADD79 pKa = 5.42LYY81 pKa = 9.9FICTPCAKK89 pKa = 10.06RR90 pKa = 11.84RR91 pKa = 11.84VRR93 pKa = 11.84QQNGRR98 pKa = 11.84QQ99 pKa = 3.23

Molecular weight: 11.31 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|E7BQA1|E7BQA1_9PAPI Protein E7 OS=Human papillomavirus 133 OX=909332 GN=E7 PE=3 SV=1
MM1 pKa = 7.6EE2 pKa = 5.14AQSSPSPLTITEE14 pKa = 3.81YY15 pKa = 10.48CARR18 pKa = 11.84FGFALADD25 pKa = 3.4VRR27 pKa = 11.84IPCNFCRR34 pKa = 11.84SYY36 pKa = 11.66LCVQDD41 pKa = 5.05CAAFDD46 pKa = 4.19LKK48 pKa = 10.5QFRR51 pKa = 11.84LLWKK55 pKa = 10.32NAFCYY60 pKa = 10.07ACCRR64 pKa = 11.84SCMRR68 pKa = 11.84LSAAYY73 pKa = 8.97EE74 pKa = 3.87VEE76 pKa = 5.19RR77 pKa = 11.84FIQCICDD84 pKa = 3.52CKK86 pKa = 11.03YY87 pKa = 10.26VTDD90 pKa = 4.62LVKK93 pKa = 10.77KK94 pKa = 9.18PLKK97 pKa = 9.42CIPMRR102 pKa = 11.84CLLCLALLDD111 pKa = 4.22FSEE114 pKa = 4.47KK115 pKa = 10.71LEE117 pKa = 3.96HH118 pKa = 6.97LFLNEE123 pKa = 3.55PFTLVRR129 pKa = 11.84GNWRR133 pKa = 11.84GFCRR137 pKa = 11.84NCIRR141 pKa = 11.84KK142 pKa = 9.01VV143 pKa = 3.12

Molecular weight: 16.65 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2411

99

609

344.4

38.94

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.599 ± 0.265

2.032 ± 0.798

6.304 ± 0.398

6.595 ± 0.502

4.314 ± 0.367

5.807 ± 0.57

1.825 ± 0.118

4.811 ± 0.814

5.516 ± 0.911

9.954 ± 0.668

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.701 ± 0.567

4.687 ± 0.749

6.221 ± 1.01

4.562 ± 0.347

5.807 ± 0.867

7.507 ± 0.7

5.973 ± 0.939

5.931 ± 0.619

1.286 ± 0.324

3.567 ± 0.679
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski