Amino acid dipepetide frequency for Callipepla squamata (Scaled quail)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.604AlaAla: 7.604 ± 0.056	1.376AlaCys: 1.376 ± 0.016	3.209AlaAsp: 3.209 ± 0.02	5.379AlaGlu: 5.379 ± 0.042	2.653AlaPhe: 2.653 ± 0.019	4.728AlaGly: 4.728 ± 0.036	1.425AlaHis: 1.425 ± 0.013	2.917AlaIle: 2.917 ± 0.023	3.635AlaLys: 3.635 ± 0.024	7.128AlaLeu: 7.128 ± 0.038	1.564AlaMet: 1.564 ± 0.016	2.184AlaAsn: 2.184 ± 0.017	3.556AlaPro: 3.556 ± 0.034	2.954AlaGln: 2.954 ± 0.02	3.447AlaArg: 3.447 ± 0.024	5.43AlaSer: 5.43 ± 0.032	3.344AlaThr: 3.344 ± 0.023	5.472AlaVal: 5.472 ± 0.031	0.779AlaTrp: 0.779 ± 0.011	1.615AlaTyr: 1.615 ± 0.015	0.001AlaXaa: 0.001 ± 0.0
Cys	1.324CysAla: 1.324 ± 0.015	0.657CysCys: 0.657 ± 0.01	1.05CysAsp: 1.05 ± 0.015	1.321CysGlu: 1.321 ± 0.018	0.912CysPhe: 0.912 ± 0.012	1.52CysGly: 1.52 ± 0.019	0.638CysHis: 0.638 ± 0.01	1.057CysIle: 1.057 ± 0.016	1.233CysLys: 1.233 ± 0.016	2.143CysLeu: 2.143 ± 0.02	0.456CysMet: 0.456 ± 0.008	0.853CysAsn: 0.853 ± 0.013	1.295CysPro: 1.295 ± 0.018	1.067CysGln: 1.067 ± 0.015	1.309CysArg: 1.309 ± 0.014	2.111CysSer: 2.111 ± 0.019	1.177CysThr: 1.177 ± 0.015	1.418CysVal: 1.418 ± 0.019	0.3CysTrp: 0.3 ± 0.006	0.645CysTyr: 0.645 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	3.163AspAla: 3.163 ± 0.022	1.074AspCys: 1.074 ± 0.015	2.756AspAsp: 2.756 ± 0.024	3.708AspGlu: 3.708 ± 0.029	2.191AspPhe: 2.191 ± 0.019	3.479AspGly: 3.479 ± 0.03	1.074AspHis: 1.074 ± 0.014	2.796AspIle: 2.796 ± 0.023	2.651AspLys: 2.651 ± 0.02	4.88AspLeu: 4.88 ± 0.026	1.154AspMet: 1.154 ± 0.013	1.835AspAsn: 1.835 ± 0.019	2.71AspPro: 2.71 ± 0.025	1.728AspGln: 1.728 ± 0.015	2.403AspArg: 2.403 ± 0.021	4.211AspSer: 4.211 ± 0.024	2.527AspThr: 2.527 ± 0.017	3.418AspVal: 3.418 ± 0.032	0.601AspTrp: 0.601 ± 0.01	1.551AspTyr: 1.551 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	5.087GluAla: 5.087 ± 0.042	1.306GluCys: 1.306 ± 0.021	4.543GluAsp: 4.543 ± 0.029	8.431GluGlu: 8.431 ± 0.075	2.121GluPhe: 2.121 ± 0.017	4.101GluGly: 4.101 ± 0.035	1.624GluHis: 1.624 ± 0.017	3.356GluIle: 3.356 ± 0.026	5.573GluLys: 5.573 ± 0.047	6.788GluLeu: 6.788 ± 0.047	1.876GluMet: 1.876 ± 0.018	3.291GluAsn: 3.291 ± 0.025	2.98GluPro: 2.98 ± 0.029	3.396GluGln: 3.396 ± 0.028	4.139GluArg: 4.139 ± 0.035	4.544GluSer: 4.544 ± 0.032	3.441GluThr: 3.441 ± 0.028	4.408GluVal: 4.408 ± 0.032	0.73GluTrp: 0.73 ± 0.01	1.748GluTyr: 1.748 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	2.132PheAla: 2.132 ± 0.02	0.99PheCys: 0.99 ± 0.011	1.758PheAsp: 1.758 ± 0.015	2.058PheGlu: 2.058 ± 0.017	1.706PhePhe: 1.706 ± 0.021	2.255PheGly: 2.255 ± 0.02	1.055PheHis: 1.055 ± 0.012	1.934PheIle: 1.934 ± 0.017	1.833PheLys: 1.833 ± 0.02	4.056PheLeu: 4.056 ± 0.031	0.79PheMet: 0.79 ± 0.009	1.406PheAsn: 1.406 ± 0.014	1.978PhePro: 1.978 ± 0.019	1.791PheGln: 1.791 ± 0.015	1.908PheArg: 1.908 ± 0.018	3.404PheSer: 3.404 ± 0.023	2.096PheThr: 2.096 ± 0.016	2.367PheVal: 2.367 ± 0.02	0.501PheTrp: 0.501 ± 0.009	1.238PheTyr: 1.238 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	4.218GlyAla: 4.218 ± 0.034	1.33GlyCys: 1.33 ± 0.017	3.14GlyAsp: 3.14 ± 0.028	4.047GlyGlu: 4.047 ± 0.036	2.408GlyPhe: 2.408 ± 0.024	4.656GlyGly: 4.656 ± 0.049	1.556GlyHis: 1.556 ± 0.017	2.879GlyIle: 2.879 ± 0.024	3.783GlyLys: 3.783 ± 0.029	5.371GlyLeu: 5.371 ± 0.033	1.4GlyMet: 1.4 ± 0.016	2.49GlyAsn: 2.49 ± 0.02	3.22GlyPro: 3.22 ± 0.059	2.582GlyGln: 2.582 ± 0.024	3.58GlyArg: 3.58 ± 0.029	5.55GlySer: 5.55 ± 0.033	3.639GlyThr: 3.639 ± 0.028	3.54GlyVal: 3.54 ± 0.03	0.771GlyTrp: 0.771 ± 0.011	1.833GlyTyr: 1.833 ± 0.021	0.001GlyXaa: 0.001 ± 0.0
His	1.384HisAla: 1.384 ± 0.013	0.702HisCys: 0.702 ± 0.01	0.919HisAsp: 0.919 ± 0.01	1.378HisGlu: 1.378 ± 0.015	1.072HisPhe: 1.072 ± 0.011	1.565HisGly: 1.565 ± 0.016	0.834HisHis: 0.834 ± 0.012	1.234HisIle: 1.234 ± 0.013	1.262HisLys: 1.262 ± 0.013	2.721HisLeu: 2.721 ± 0.021	0.576HisMet: 0.576 ± 0.009	0.917HisAsn: 0.917 ± 0.013	1.501HisPro: 1.501 ± 0.014	1.111HisGln: 1.111 ± 0.013	1.497HisArg: 1.497 ± 0.017	2.198HisSer: 2.198 ± 0.017	1.251HisThr: 1.251 ± 0.015	1.534HisVal: 1.534 ± 0.015	0.33HisTrp: 0.33 ± 0.006	0.858HisTyr: 0.858 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	2.872IleAla: 2.872 ± 0.021	1.132IleCys: 1.132 ± 0.014	2.182IleAsp: 2.182 ± 0.022	2.725IleGlu: 2.725 ± 0.025	1.974IlePhe: 1.974 ± 0.019	2.296IleGly: 2.296 ± 0.022	1.246IleHis: 1.246 ± 0.013	2.452IleIle: 2.452 ± 0.026	2.712IleLys: 2.712 ± 0.021	4.585IleLeu: 4.585 ± 0.032	1.003IleMet: 1.003 ± 0.013	1.953IleAsn: 1.953 ± 0.021	2.675IlePro: 2.675 ± 0.02	2.281IleGln: 2.281 ± 0.018	2.411IleArg: 2.411 ± 0.017	3.937IleSer: 3.937 ± 0.026	2.699IleThr: 2.699 ± 0.025	2.77IleVal: 2.77 ± 0.023	0.536IleTrp: 0.536 ± 0.008	1.448IleTyr: 1.448 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	4.113LysAla: 4.113 ± 0.026	1.132LysCys: 1.132 ± 0.013	3.279LysAsp: 3.279 ± 0.024	5.411LysGlu: 5.411 ± 0.046	1.763LysPhe: 1.763 ± 0.018	3.311LysGly: 3.311 ± 0.042	1.459LysHis: 1.459 ± 0.016	2.878LysIle: 2.878 ± 0.023	4.944LysLys: 4.944 ± 0.038	5.41LysLeu: 5.41 ± 0.034	1.581LysMet: 1.581 ± 0.016	2.499LysAsn: 2.499 ± 0.02	2.913LysPro: 2.913 ± 0.03	2.787LysGln: 2.787 ± 0.024	3.405LysArg: 3.405 ± 0.023	4.007LysSer: 4.007 ± 0.03	3.082LysThr: 3.082 ± 0.024	3.595LysVal: 3.595 ± 0.03	0.617LysTrp: 0.617 ± 0.01	1.734LysTyr: 1.734 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	6.549LeuAla: 6.549 ± 0.041	2.301LeuCys: 2.301 ± 0.023	4.709LeuAsp: 4.709 ± 0.031	7.075LeuGlu: 7.075 ± 0.051	3.494LeuPhe: 3.494 ± 0.029	5.434LeuGly: 5.434 ± 0.028	2.7LeuHis: 2.7 ± 0.021	3.941LeuIle: 3.941 ± 0.029	6.009LeuLys: 6.009 ± 0.041	10.669LeuLeu: 10.669 ± 0.066	2.054LeuMet: 2.054 ± 0.016	3.644LeuAsn: 3.644 ± 0.026	5.651LeuPro: 5.651 ± 0.037	5.742LeuGln: 5.742 ± 0.044	5.725LeuArg: 5.725 ± 0.036	7.987LeuSer: 7.987 ± 0.036	4.832LeuThr: 4.832 ± 0.032	5.449LeuVal: 5.449 ± 0.035	1.091LeuTrp: 1.091 ± 0.012	2.674LeuTyr: 2.674 ± 0.023	0.001LeuXaa: 0.001 ± 0.0
Met	1.934MetAla: 1.934 ± 0.016	0.429MetCys: 0.429 ± 0.008	1.267MetAsp: 1.267 ± 0.015	1.977MetGlu: 1.977 ± 0.017	0.797MetPhe: 0.797 ± 0.011	1.311MetGly: 1.311 ± 0.015	0.509MetHis: 0.509 ± 0.008	0.881MetIle: 0.881 ± 0.011	1.546MetLys: 1.546 ± 0.015	2.063MetLeu: 2.063 ± 0.018	0.605MetMet: 0.605 ± 0.01	0.925MetAsn: 0.925 ± 0.013	1.098MetPro: 1.098 ± 0.019	1.015MetGln: 1.015 ± 0.012	1.101MetArg: 1.101 ± 0.012	1.621MetSer: 1.621 ± 0.016	1.087MetThr: 1.087 ± 0.013	1.424MetVal: 1.424 ± 0.014	0.253MetTrp: 0.253 ± 0.006	0.615MetTyr: 0.615 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	2.357AsnAla: 2.357 ± 0.019	0.923AsnCys: 0.923 ± 0.013	1.625AsnAsp: 1.625 ± 0.019	2.435AsnGlu: 2.435 ± 0.021	1.495AsnPhe: 1.495 ± 0.014	2.618AsnGly: 2.618 ± 0.025	0.916AsnHis: 0.916 ± 0.012	2.261AsnIle: 2.261 ± 0.023	2.323AsnLys: 2.323 ± 0.022	3.777AsnLeu: 3.777 ± 0.029	0.95AsnMet: 0.95 ± 0.012	1.644AsnAsn: 1.644 ± 0.019	2.115AsnPro: 2.115 ± 0.017	1.575AsnGln: 1.575 ± 0.015	1.873AsnArg: 1.873 ± 0.017	3.261AsnSer: 3.261 ± 0.03	2.087AsnThr: 2.087 ± 0.023	2.446AsnVal: 2.446 ± 0.02	0.457AsnTrp: 0.457 ± 0.008	1.177AsnTyr: 1.177 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	4.434ProAla: 4.434 ± 0.04	1.161ProCys: 1.161 ± 0.015	2.658ProAsp: 2.658 ± 0.026	4.105ProGlu: 4.105 ± 0.04	1.845ProPhe: 1.845 ± 0.018	4.273ProGly: 4.273 ± 0.081	1.314ProHis: 1.314 ± 0.015	1.885ProIle: 1.885 ± 0.019	2.746ProLys: 2.746 ± 0.043	4.778ProLeu: 4.778 ± 0.029	0.988ProMet: 0.988 ± 0.01	1.784ProAsn: 1.784 ± 0.018	4.968ProPro: 4.968 ± 0.07	2.452ProGln: 2.452 ± 0.024	2.833ProArg: 2.833 ± 0.024	5.088ProSer: 5.088 ± 0.041	2.732ProThr: 2.732 ± 0.026	3.714ProVal: 3.714 ± 0.026	0.594ProTrp: 0.594 ± 0.009	1.41ProTyr: 1.41 ± 0.015	0.001ProXaa: 0.001 ± 0.0
Gln	3.132GlnAla: 3.132 ± 0.023	0.968GlnCys: 0.968 ± 0.015	2.218GlnAsp: 2.218 ± 0.017	3.81GlnGlu: 3.81 ± 0.032	1.376GlnPhe: 1.376 ± 0.014	2.55GlnGly: 2.55 ± 0.026	1.355GlnHis: 1.355 ± 0.014	2.02GlnIle: 2.02 ± 0.016	3.024GlnLys: 3.024 ± 0.025	4.729GlnLeu: 4.729 ± 0.031	1.104GlnMet: 1.104 ± 0.012	1.92GlnAsn: 1.92 ± 0.019	2.494GlnPro: 2.494 ± 0.027	3.041GlnGln: 3.041 ± 0.043	2.767GlnArg: 2.767 ± 0.023	3.18GlnSer: 3.18 ± 0.023	2.195GlnThr: 2.195 ± 0.019	2.725GlnVal: 2.725 ± 0.02	0.523GlnTrp: 0.523 ± 0.009	1.227GlnTyr: 1.227 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	3.803ArgAla: 3.803 ± 0.029	1.249ArgCys: 1.249 ± 0.017	2.797ArgAsp: 2.797 ± 0.02	3.894ArgGlu: 3.894 ± 0.031	1.931ArgPhe: 1.931 ± 0.015	3.331ArgGly: 3.331 ± 0.031	1.446ArgHis: 1.446 ± 0.014	2.464ArgIle: 2.464 ± 0.016	3.658ArgLys: 3.658 ± 0.027	5.092ArgLeu: 5.092 ± 0.032	1.238ArgMet: 1.238 ± 0.013	2.149ArgAsn: 2.149 ± 0.018	2.576ArgPro: 2.576 ± 0.024	2.506ArgGln: 2.506 ± 0.022	4.142ArgArg: 4.142 ± 0.042	4.182ArgSer: 4.182 ± 0.033	2.672ArgThr: 2.672 ± 0.018	3.137ArgVal: 3.137 ± 0.024	0.674ArgTrp: 0.674 ± 0.01	1.615ArgTyr: 1.615 ± 0.015	0.001ArgXaa: 0.001 ± 0.0
Ser	5.625SerAla: 5.625 ± 0.033	1.947SerCys: 1.947 ± 0.019	4.032SerAsp: 4.032 ± 0.028	5.322SerGlu: 5.322 ± 0.034	3.097SerPhe: 3.097 ± 0.022	5.22SerGly: 5.22 ± 0.029	1.998SerHis: 1.998 ± 0.017	3.454SerIle: 3.454 ± 0.027	4.269SerLys: 4.269 ± 0.03	7.878SerLeu: 7.878 ± 0.04	1.642SerMet: 1.642 ± 0.015	2.849SerAsn: 2.849 ± 0.024	5.405SerPro: 5.405 ± 0.048	3.608SerGln: 3.608 ± 0.027	4.191SerArg: 4.191 ± 0.032	9.298SerSer: 9.298 ± 0.07	4.566SerThr: 4.566 ± 0.032	5.228SerVal: 5.228 ± 0.025	0.965SerTrp: 0.965 ± 0.013	2.208SerTyr: 2.208 ± 0.017	0.001SerXaa: 0.001 ± 0.0
Thr	4.1ThrAla: 4.1 ± 0.028	1.276ThrCys: 1.276 ± 0.017	2.663ThrAsp: 2.663 ± 0.02	3.738ThrGlu: 3.738 ± 0.028	2.095ThrPhe: 2.095 ± 0.02	3.327ThrGly: 3.327 ± 0.028	1.103ThrHis: 1.103 ± 0.013	2.384ThrIle: 2.384 ± 0.021	2.697ThrLys: 2.697 ± 0.024	5.017ThrLeu: 5.017 ± 0.029	1.107ThrMet: 1.107 ± 0.011	1.811ThrAsn: 1.811 ± 0.017	3.082ThrPro: 3.082 ± 0.032	2.077ThrGln: 2.077 ± 0.023	2.286ThrArg: 2.286 ± 0.019	4.453ThrSer: 4.453 ± 0.034	2.905ThrThr: 2.905 ± 0.042	4.133ThrVal: 4.133 ± 0.032	0.654ThrTrp: 0.654 ± 0.01	1.469ThrTyr: 1.469 ± 0.016	0.0ThrXaa: 0.0 ± 0.0
Val	4.334ValAla: 4.334 ± 0.029	1.562ValCys: 1.562 ± 0.019	3.023ValAsp: 3.023 ± 0.033	4.092ValGlu: 4.092 ± 0.028	2.56ValPhe: 2.56 ± 0.021	3.52ValGly: 3.52 ± 0.023	1.529ValHis: 1.529 ± 0.013	3.044ValIle: 3.044 ± 0.022	3.635ValLys: 3.635 ± 0.026	6.677ValLeu: 6.677 ± 0.039	1.411ValMet: 1.411 ± 0.013	2.434ValAsn: 2.434 ± 0.023	3.8ValPro: 3.8 ± 0.029	2.88ValGln: 2.88 ± 0.021	3.191ValArg: 3.191 ± 0.024	5.119ValSer: 5.119 ± 0.031	3.889ValThr: 3.889 ± 0.031	4.335ValVal: 4.335 ± 0.034	0.726ValTrp: 0.726 ± 0.01	1.74ValTyr: 1.74 ± 0.018	0.001ValXaa: 0.001 ± 0.0
Trp	0.71TrpAla: 0.71 ± 0.01	0.242TrpCys: 0.242 ± 0.006	0.676TrpAsp: 0.676 ± 0.009	0.796TrpGlu: 0.796 ± 0.009	0.443TrpPhe: 0.443 ± 0.007	0.695TrpGly: 0.695 ± 0.011	0.295TrpHis: 0.295 ± 0.005	0.575TrpIle: 0.575 ± 0.011	0.828TrpLys: 0.828 ± 0.01	1.217TrpLeu: 1.217 ± 0.014	0.324TrpMet: 0.324 ± 0.007	0.524TrpAsn: 0.524 ± 0.009	0.435TrpPro: 0.435 ± 0.008	0.532TrpGln: 0.532 ± 0.008	0.68TrpArg: 0.68 ± 0.009	0.851TrpSer: 0.851 ± 0.012	0.6TrpThr: 0.6 ± 0.011	0.692TrpVal: 0.692 ± 0.01	0.19TrpTrp: 0.19 ± 0.006	0.357TrpTyr: 0.357 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.529TyrAla: 1.529 ± 0.014	0.728TyrCys: 0.728 ± 0.011	1.408TyrAsp: 1.408 ± 0.016	1.776TyrGlu: 1.776 ± 0.017	1.322TyrPhe: 1.322 ± 0.013	1.799TyrGly: 1.799 ± 0.02	0.766TyrHis: 0.766 ± 0.009	1.479TyrIle: 1.479 ± 0.019	1.56TyrLys: 1.56 ± 0.024	2.752TyrLeu: 2.752 ± 0.023	0.634TyrMet: 0.634 ± 0.008	1.204TyrAsn: 1.204 ± 0.014	1.311TyrPro: 1.311 ± 0.015	1.235TyrGln: 1.235 ± 0.013	1.665TyrArg: 1.665 ± 0.016	2.374TyrSer: 2.374 ± 0.021	1.556TyrThr: 1.556 ± 0.016	1.693TyrVal: 1.693 ± 0.016	0.37TyrTrp: 0.37 ± 0.009	1.032TyrTyr: 1.032 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.002XaaGly: 0.002 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.088XaaXaa: 0.088 ± 0.015

Statistics based on 16973 proteins (8302635 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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