Amino acid dipepetide frequency for Phialocephala subalpina

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.005AlaAla: 8.005 ± 0.042	1.11AlaCys: 1.11 ± 0.011	3.795AlaAsp: 3.795 ± 0.022	4.868AlaGlu: 4.868 ± 0.026	3.193AlaPhe: 3.193 ± 0.021	5.504AlaGly: 5.504 ± 0.026	1.591AlaHis: 1.591 ± 0.014	4.555AlaIle: 4.555 ± 0.028	4.064AlaLys: 4.064 ± 0.025	7.47AlaLeu: 7.47 ± 0.033	1.91AlaMet: 1.91 ± 0.015	2.979AlaAsn: 2.979 ± 0.021	4.265AlaPro: 4.265 ± 0.026	3.021AlaGln: 3.021 ± 0.022	4.308AlaArg: 4.308 ± 0.025	6.994AlaSer: 6.994 ± 0.037	5.186AlaThr: 5.186 ± 0.03	4.998AlaVal: 4.998 ± 0.026	1.184AlaTrp: 1.184 ± 0.012	2.139AlaTyr: 2.139 ± 0.015	0.0AlaXaa: 0.0 ± 0.0
Cys	0.955CysAla: 0.955 ± 0.011	0.281CysCys: 0.281 ± 0.007	0.712CysAsp: 0.712 ± 0.009	0.673CysGlu: 0.673 ± 0.008	0.606CysPhe: 0.606 ± 0.008	1.057CysGly: 1.057 ± 0.014	0.348CysHis: 0.348 ± 0.007	0.813CysIle: 0.813 ± 0.01	0.599CysLys: 0.599 ± 0.009	1.359CysLeu: 1.359 ± 0.013	0.286CysMet: 0.286 ± 0.005	0.491CysAsn: 0.491 ± 0.008	0.709CysPro: 0.709 ± 0.01	0.516CysGln: 0.516 ± 0.008	0.759CysArg: 0.759 ± 0.01	1.064CysSer: 1.064 ± 0.012	0.794CysThr: 0.794 ± 0.009	0.798CysVal: 0.798 ± 0.01	0.247CysTrp: 0.247 ± 0.006	0.394CysTyr: 0.394 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	4.219AspAla: 4.219 ± 0.02	0.68AspCys: 0.68 ± 0.009	3.713AspAsp: 3.713 ± 0.032	4.319AspGlu: 4.319 ± 0.029	2.334AspPhe: 2.334 ± 0.015	3.933AspGly: 3.933 ± 0.022	1.2AspHis: 1.2 ± 0.012	3.264AspIle: 3.264 ± 0.021	2.335AspLys: 2.335 ± 0.019	5.05AspLeu: 5.05 ± 0.025	1.207AspMet: 1.207 ± 0.012	1.906AspAsn: 1.906 ± 0.015	3.197AspPro: 3.197 ± 0.02	1.782AspGln: 1.782 ± 0.014	2.742AspArg: 2.742 ± 0.017	4.012AspSer: 4.012 ± 0.026	2.935AspThr: 2.935 ± 0.018	3.47AspVal: 3.47 ± 0.019	0.937AspTrp: 0.937 ± 0.01	1.577AspTyr: 1.577 ± 0.012	0.0AspXaa: 0.0 ± 0.0
Glu	5.148GluAla: 5.148 ± 0.029	0.704GluCys: 0.704 ± 0.01	4.191GluAsp: 4.191 ± 0.027	5.545GluGlu: 5.545 ± 0.048	2.062GluPhe: 2.062 ± 0.016	3.908GluGly: 3.908 ± 0.025	1.41GluHis: 1.41 ± 0.013	3.384GluIle: 3.384 ± 0.02	4.028GluLys: 4.028 ± 0.026	5.278GluLeu: 5.278 ± 0.03	1.524GluMet: 1.524 ± 0.012	2.481GluAsn: 2.481 ± 0.015	2.578GluPro: 2.578 ± 0.026	2.313GluGln: 2.313 ± 0.017	3.858GluArg: 3.858 ± 0.026	4.353GluSer: 4.353 ± 0.028	3.442GluThr: 3.442 ± 0.022	3.802GluVal: 3.802 ± 0.023	0.958GluTrp: 0.958 ± 0.01	1.776GluTyr: 1.776 ± 0.015	0.0GluXaa: 0.0 ± 0.0
Phe	3.081PheAla: 3.081 ± 0.022	0.623PheCys: 0.623 ± 0.01	2.342PheAsp: 2.342 ± 0.019	2.387PheGlu: 2.387 ± 0.015	1.709PhePhe: 1.709 ± 0.017	3.061PheGly: 3.061 ± 0.02	0.896PheHis: 0.896 ± 0.01	1.968PheIle: 1.968 ± 0.015	1.713PheLys: 1.713 ± 0.013	3.638PheLeu: 3.638 ± 0.022	0.833PheMet: 0.833 ± 0.009	1.543PheAsn: 1.543 ± 0.014	2.036PhePro: 2.036 ± 0.014	1.518PheGln: 1.518 ± 0.013	1.931PheArg: 1.931 ± 0.014	3.182PheSer: 3.182 ± 0.019	2.285PheThr: 2.285 ± 0.015	2.417PheVal: 2.417 ± 0.019	0.723PheTrp: 0.723 ± 0.009	1.139PheTyr: 1.139 ± 0.012	0.0PheXaa: 0.0 ± 0.0
Gly	5.053GlyAla: 5.053 ± 0.029	0.97GlyCys: 0.97 ± 0.013	3.463GlyAsp: 3.463 ± 0.021	3.721GlyGlu: 3.721 ± 0.025	2.946GlyPhe: 2.946 ± 0.02	5.681GlyGly: 5.681 ± 0.039	1.641GlyHis: 1.641 ± 0.015	3.853GlyIle: 3.853 ± 0.019	3.716GlyLys: 3.716 ± 0.023	6.073GlyLeu: 6.073 ± 0.027	1.66GlyMet: 1.66 ± 0.013	2.765GlyAsn: 2.765 ± 0.02	3.192GlyPro: 3.192 ± 0.021	2.391GlyGln: 2.391 ± 0.018	3.813GlyArg: 3.813 ± 0.022	5.668GlySer: 5.668 ± 0.032	4.23GlyThr: 4.23 ± 0.023	4.307GlyVal: 4.307 ± 0.025	1.247GlyTrp: 1.247 ± 0.013	2.2GlyTyr: 2.2 ± 0.019	0.001GlyXaa: 0.001 ± 0.0
His	1.649HisAla: 1.649 ± 0.014	0.362HisCys: 0.362 ± 0.006	1.238HisAsp: 1.238 ± 0.012	1.361HisGlu: 1.361 ± 0.013	0.95HisPhe: 0.95 ± 0.011	1.617HisGly: 1.617 ± 0.015	0.779HisHis: 0.779 ± 0.01	1.237HisIle: 1.237 ± 0.011	0.94HisLys: 0.94 ± 0.01	2.235HisLeu: 2.235 ± 0.018	0.467HisMet: 0.467 ± 0.007	0.858HisAsn: 0.858 ± 0.009	1.519HisPro: 1.519 ± 0.017	0.959HisGln: 0.959 ± 0.01	1.387HisArg: 1.387 ± 0.012	1.762HisSer: 1.762 ± 0.017	1.266HisThr: 1.266 ± 0.013	1.346HisVal: 1.346 ± 0.012	0.366HisTrp: 0.366 ± 0.006	0.691HisTyr: 0.691 ± 0.007	0.0HisXaa: 0.0 ± 0.0
Ile	4.427IleAla: 4.427 ± 0.022	0.867IleCys: 0.867 ± 0.011	3.016IleAsp: 3.016 ± 0.018	3.202IleGlu: 3.202 ± 0.018	2.268IlePhe: 2.268 ± 0.02	3.5IleGly: 3.5 ± 0.021	1.243IleHis: 1.243 ± 0.009	2.877IleIle: 2.877 ± 0.021	2.393IleLys: 2.393 ± 0.018	5.038IleLeu: 5.038 ± 0.029	1.112IleMet: 1.112 ± 0.012	2.012IleAsn: 2.012 ± 0.013	3.227IlePro: 3.227 ± 0.02	2.036IleGln: 2.036 ± 0.016	2.763IleArg: 2.763 ± 0.019	4.357IleSer: 4.357 ± 0.023	3.2IleThr: 3.2 ± 0.019	3.372IleVal: 3.372 ± 0.022	0.877IleTrp: 0.877 ± 0.01	1.565IleTyr: 1.565 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	4.324LysAla: 4.324 ± 0.027	0.585LysCys: 0.585 ± 0.009	2.981LysAsp: 2.981 ± 0.023	3.713LysGlu: 3.713 ± 0.028	1.651LysPhe: 1.651 ± 0.014	3.228LysGly: 3.228 ± 0.023	1.191LysHis: 1.191 ± 0.012	2.586LysIle: 2.586 ± 0.016	3.463LysLys: 3.463 ± 0.036	4.296LysLeu: 4.296 ± 0.024	1.106LysMet: 1.106 ± 0.011	1.893LysAsn: 1.893 ± 0.014	2.607LysPro: 2.607 ± 0.021	1.8LysGln: 1.8 ± 0.015	3.297LysArg: 3.297 ± 0.022	3.774LysSer: 3.774 ± 0.022	2.986LysThr: 2.986 ± 0.019	3.02LysVal: 3.02 ± 0.017	0.754LysTrp: 0.754 ± 0.008	1.495LysTyr: 1.495 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	7.535LeuAla: 7.535 ± 0.032	1.315LeuCys: 1.315 ± 0.014	5.108LeuAsp: 5.108 ± 0.026	5.795LeuGlu: 5.795 ± 0.032	3.399LeuPhe: 3.399 ± 0.022	6.005LeuGly: 6.005 ± 0.031	2.215LeuHis: 2.215 ± 0.017	4.229LeuIle: 4.229 ± 0.026	4.495LeuLys: 4.495 ± 0.024	8.559LeuLeu: 8.559 ± 0.045	1.811LeuMet: 1.811 ± 0.014	3.324LeuAsn: 3.324 ± 0.019	5.467LeuPro: 5.467 ± 0.027	3.84LeuGln: 3.84 ± 0.026	5.361LeuArg: 5.361 ± 0.029	7.479LeuSer: 7.479 ± 0.033	4.905LeuThr: 4.905 ± 0.028	5.286LeuVal: 5.286 ± 0.027	1.342LeuTrp: 1.342 ± 0.014	2.419LeuTyr: 2.419 ± 0.017	0.0LeuXaa: 0.0 ± 0.0
Met	2.146MetAla: 2.146 ± 0.016	0.26MetCys: 0.26 ± 0.005	1.236MetAsp: 1.236 ± 0.013	1.305MetGlu: 1.305 ± 0.013	0.824MetPhe: 0.824 ± 0.01	1.484MetGly: 1.484 ± 0.013	0.471MetHis: 0.471 ± 0.007	1.089MetIle: 1.089 ± 0.012	1.153MetLys: 1.153 ± 0.009	1.862MetLeu: 1.862 ± 0.016	0.592MetMet: 0.592 ± 0.008	0.862MetAsn: 0.862 ± 0.011	1.232MetPro: 1.232 ± 0.012	0.829MetGln: 0.829 ± 0.01	1.195MetArg: 1.195 ± 0.011	1.938MetSer: 1.938 ± 0.014	1.302MetThr: 1.302 ± 0.012	1.298MetVal: 1.298 ± 0.013	0.282MetTrp: 0.282 ± 0.006	0.547MetTyr: 0.547 ± 0.007	0.0MetXaa: 0.0 ± 0.0
Asn	3.167AsnAla: 3.167 ± 0.018	0.525AsnCys: 0.525 ± 0.008	2.008AsnAsp: 2.008 ± 0.015	2.153AsnGlu: 2.153 ± 0.018	1.57AsnPhe: 1.57 ± 0.015	3.259AsnGly: 3.259 ± 0.022	0.866AsnHis: 0.866 ± 0.009	2.316AsnIle: 2.316 ± 0.014	1.579AsnLys: 1.579 ± 0.015	3.487AsnLeu: 3.487 ± 0.019	0.866AsnMet: 0.866 ± 0.01	1.621AsnAsn: 1.621 ± 0.017	2.444AsnPro: 2.444 ± 0.016	1.388AsnGln: 1.388 ± 0.013	1.848AsnArg: 1.848 ± 0.014	3.118AsnSer: 3.118 ± 0.022	2.463AsnThr: 2.463 ± 0.017	2.398AsnVal: 2.398 ± 0.015	0.635AsnTrp: 0.635 ± 0.008	1.146AsnTyr: 1.146 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	4.567ProAla: 4.567 ± 0.031	0.55ProCys: 0.55 ± 0.009	2.926ProAsp: 2.926 ± 0.02	3.676ProGlu: 3.676 ± 0.024	2.058ProPhe: 2.058 ± 0.015	3.606ProGly: 3.606 ± 0.02	1.189ProHis: 1.189 ± 0.013	2.742ProIle: 2.742 ± 0.019	2.797ProLys: 2.797 ± 0.021	4.668ProLeu: 4.668 ± 0.024	1.055ProMet: 1.055 ± 0.01	2.301ProAsn: 2.301 ± 0.017	4.567ProPro: 4.567 ± 0.05	2.339ProGln: 2.339 ± 0.023	3.16ProArg: 3.16 ± 0.022	5.722ProSer: 5.722 ± 0.039	4.0ProThr: 4.0 ± 0.026	3.199ProVal: 3.199 ± 0.02	0.763ProTrp: 0.763 ± 0.009	1.492ProTyr: 1.492 ± 0.014	0.0ProXaa: 0.0 ± 0.0
Gln	3.243GlnAla: 3.243 ± 0.022	0.498GlnCys: 0.498 ± 0.008	2.057GlnAsp: 2.057 ± 0.018	2.407GlnGlu: 2.407 ± 0.02	1.318GlnPhe: 1.318 ± 0.013	2.308GlnGly: 2.308 ± 0.019	0.999GlnHis: 0.999 ± 0.012	1.996GlnIle: 1.996 ± 0.015	1.995GlnLys: 1.995 ± 0.016	3.286GlnLeu: 3.286 ± 0.022	0.872GlnMet: 0.872 ± 0.01	1.669GlnAsn: 1.669 ± 0.015	2.179GlnPro: 2.179 ± 0.022	2.081GlnGln: 2.081 ± 0.024	2.41GlnArg: 2.41 ± 0.018	3.031GlnSer: 3.031 ± 0.019	2.302GlnThr: 2.302 ± 0.016	2.13GlnVal: 2.13 ± 0.016	0.583GlnTrp: 0.583 ± 0.008	1.239GlnTyr: 1.239 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	4.074ArgAla: 4.074 ± 0.022	0.738ArgCys: 0.738 ± 0.01	3.156ArgAsp: 3.156 ± 0.022	3.661ArgGlu: 3.661 ± 0.025	2.034ArgPhe: 2.034 ± 0.015	3.513ArgGly: 3.513 ± 0.024	1.425ArgHis: 1.425 ± 0.013	2.925ArgIle: 2.925 ± 0.019	3.424ArgLys: 3.424 ± 0.023	5.115ArgLeu: 5.115 ± 0.029	1.24ArgMet: 1.24 ± 0.012	2.253ArgAsn: 2.253 ± 0.016	3.082ArgPro: 3.082 ± 0.02	2.318ArgGln: 2.318 ± 0.017	4.404ArgArg: 4.404 ± 0.033	4.415ArgSer: 4.415 ± 0.027	3.17ArgThr: 3.17 ± 0.021	3.072ArgVal: 3.072 ± 0.02	0.952ArgTrp: 0.952 ± 0.01	1.607ArgTyr: 1.607 ± 0.013	0.0ArgXaa: 0.0 ± 0.0
Ser	6.325SerAla: 6.325 ± 0.034	0.997SerCys: 0.997 ± 0.014	4.041SerAsp: 4.041 ± 0.021	4.241SerGlu: 4.241 ± 0.026	3.203SerPhe: 3.203 ± 0.02	5.535SerGly: 5.535 ± 0.031	1.866SerHis: 1.866 ± 0.016	4.517SerIle: 4.517 ± 0.027	4.012SerLys: 4.012 ± 0.024	7.299SerLeu: 7.299 ± 0.036	1.792SerMet: 1.792 ± 0.013	3.342SerAsn: 3.342 ± 0.022	5.279SerPro: 5.279 ± 0.032	3.275SerGln: 3.275 ± 0.025	4.756SerArg: 4.756 ± 0.027	9.368SerSer: 9.368 ± 0.103	6.228SerThr: 6.228 ± 0.044	4.511SerVal: 4.511 ± 0.031	1.273SerTrp: 1.273 ± 0.014	2.219SerTyr: 2.219 ± 0.015	0.0SerXaa: 0.0 ± 0.0
Thr	5.007ThrAla: 5.007 ± 0.026	0.868ThrCys: 0.868 ± 0.011	2.743ThrAsp: 2.743 ± 0.017	3.096ThrGlu: 3.096 ± 0.019	2.554ThrPhe: 2.554 ± 0.017	4.108ThrGly: 4.108 ± 0.028	1.231ThrHis: 1.231 ± 0.011	3.547ThrIle: 3.547 ± 0.024	2.875ThrLys: 2.875 ± 0.019	5.509ThrLeu: 5.509 ± 0.031	1.25ThrMet: 1.25 ± 0.013	2.393ThrAsn: 2.393 ± 0.018	4.272ThrPro: 4.272 ± 0.03	2.116ThrGln: 2.116 ± 0.016	3.01ThrArg: 3.01 ± 0.018	6.011ThrSer: 6.011 ± 0.045	4.648ThrThr: 4.648 ± 0.036	3.617ThrVal: 3.617 ± 0.021	0.961ThrTrp: 0.961 ± 0.011	1.759ThrTyr: 1.759 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	4.922ValAla: 4.922 ± 0.024	0.825ValCys: 0.825 ± 0.009	3.523ValAsp: 3.523 ± 0.02	4.007ValGlu: 4.007 ± 0.025	2.474ValPhe: 2.474 ± 0.017	4.047ValGly: 4.047 ± 0.026	1.307ValHis: 1.307 ± 0.011	3.025ValIle: 3.025 ± 0.02	3.063ValLys: 3.063 ± 0.019	5.55ValLeu: 5.55 ± 0.029	1.299ValMet: 1.299 ± 0.012	2.23ValAsn: 2.23 ± 0.015	3.36ValPro: 3.36 ± 0.021	2.292ValGln: 2.292 ± 0.017	3.087ValArg: 3.087 ± 0.019	4.513ValSer: 4.513 ± 0.032	3.454ValThr: 3.454 ± 0.023	4.245ValVal: 4.245 ± 0.025	0.922ValTrp: 0.922 ± 0.01	1.728ValTyr: 1.728 ± 0.014	0.0ValXaa: 0.0 ± 0.0
Trp	1.167TrpAla: 1.167 ± 0.012	0.22TrpCys: 0.22 ± 0.005	0.917TrpAsp: 0.917 ± 0.012	0.951TrpGlu: 0.951 ± 0.011	0.595TrpPhe: 0.595 ± 0.008	1.062TrpGly: 1.062 ± 0.013	0.367TrpHis: 0.367 ± 0.007	0.924TrpIle: 0.924 ± 0.01	0.922TrpLys: 0.922 ± 0.009	1.405TrpLeu: 1.405 ± 0.013	0.411TrpMet: 0.411 ± 0.006	0.716TrpAsn: 0.716 ± 0.009	0.653TrpPro: 0.653 ± 0.008	0.596TrpGln: 0.596 ± 0.007	0.946TrpArg: 0.946 ± 0.011	1.154TrpSer: 1.154 ± 0.011	1.037TrpThr: 1.037 ± 0.011	0.964TrpVal: 0.964 ± 0.009	0.302TrpTrp: 0.302 ± 0.007	0.49TrpTyr: 0.49 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.123TyrAla: 2.123 ± 0.014	0.482TyrCys: 0.482 ± 0.007	1.646TyrAsp: 1.646 ± 0.014	1.661TyrGlu: 1.661 ± 0.013	1.278TyrPhe: 1.278 ± 0.012	2.174TyrGly: 2.174 ± 0.017	0.75TyrHis: 0.75 ± 0.008	1.505TyrIle: 1.505 ± 0.013	1.185TyrLys: 1.185 ± 0.011	2.714TyrLeu: 2.714 ± 0.019	0.616TyrMet: 0.616 ± 0.009	1.218TyrAsn: 1.218 ± 0.011	1.512TyrPro: 1.512 ± 0.015	1.191TyrGln: 1.191 ± 0.012	1.543TyrArg: 1.543 ± 0.011	2.163TyrSer: 2.163 ± 0.016	1.748TyrThr: 1.748 ± 0.017	1.622TyrVal: 1.622 ± 0.013	0.492TyrTrp: 0.492 ± 0.008	0.947TyrTyr: 0.947 ± 0.01	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.018XaaXaa: 0.018 ± 0.005

Statistics based on 20170 proteins (9780577 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---