human papillomavirus 102

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Alphapapillomavirus; Alphapapillomavirus 3

Average proteome isoelectric point is 6.28

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q2VJC0|Q2VJC0_9PAPI Protein E6 OS=human papillomavirus 102 OX=338327 GN=E6 PE=3 SV=1
MM1 pKa = 7.52HH2 pKa = 6.83GHH4 pKa = 7.45AATIADD10 pKa = 3.63IVLEE14 pKa = 4.14EE15 pKa = 4.62LPDD18 pKa = 5.04VIDD21 pKa = 4.91LYY23 pKa = 11.49CNEE26 pKa = 3.95QAIDD30 pKa = 3.54SSEE33 pKa = 4.24EE34 pKa = 3.61EE35 pKa = 4.32DD36 pKa = 4.32EE37 pKa = 4.33RR38 pKa = 11.84DD39 pKa = 3.8CVRR42 pKa = 11.84DD43 pKa = 3.65QLAEE47 pKa = 4.0QAKK50 pKa = 8.39QAYY53 pKa = 9.0RR54 pKa = 11.84VVTKK58 pKa = 10.56CGMCGQSLRR67 pKa = 11.84LAVLCGDD74 pKa = 3.36TDD76 pKa = 3.19IRR78 pKa = 11.84RR79 pKa = 11.84LQEE82 pKa = 3.93LLVNAVDD89 pKa = 4.57IVCPSCAA96 pKa = 3.61

Molecular weight: 10.59 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|Q2VJB7|Q2VJB7_9PAPI Regulatory protein E2 OS=human papillomavirus 102 OX=338327 GN=E2 PE=3 SV=1
MM1 pKa = 6.94GQKK4 pKa = 9.24TYY6 pKa = 10.31GKK8 pKa = 10.27CMWATMLFTNHH19 pKa = 5.36ATLYY23 pKa = 9.15LAPRR27 pKa = 11.84TPCQKK32 pKa = 10.47YY33 pKa = 9.61PLLQLVTGYY42 pKa = 7.62HH43 pKa = 6.18TPTNPPPAPRR53 pKa = 11.84CWAPPRR59 pKa = 11.84APPKK63 pKa = 9.55CRR65 pKa = 11.84RR66 pKa = 11.84RR67 pKa = 11.84LVSDD71 pKa = 3.33SDD73 pKa = 3.82STEE76 pKa = 4.25TEE78 pKa = 4.05QSSPTPPKK86 pKa = 11.02NNIKK90 pKa = 10.56SGWTLVPTDD99 pKa = 3.55STVTLSAQNAQGTTVTVTIHH119 pKa = 6.25LL120 pKa = 4.2

Molecular weight: 13.22 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2516

96

651

359.4

40.09

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.836 ± 0.719

3.06 ± 0.89

5.604 ± 0.465

5.048 ± 1.053

3.776 ± 0.519

6.439 ± 0.576

2.464 ± 0.415

4.332 ± 0.471

4.571 ± 0.605

8.625 ± 0.957

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.186 ± 0.462

3.14 ± 0.383

6.359 ± 1.107

4.69 ± 0.465

5.246 ± 0.231

7.273 ± 0.82

7.83 ± 1.118

7.075 ± 0.532

1.669 ± 0.265

3.776 ± 0.356
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski