Amino acid dipepetide frequency for Armillaria ostoyae (Armillaria root rot fungus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.987AlaAla: 6.987 ± 0.042	1.085AlaCys: 1.085 ± 0.012	3.87AlaAsp: 3.87 ± 0.02	4.397AlaGlu: 4.397 ± 0.021	3.228AlaPhe: 3.228 ± 0.021	4.603AlaGly: 4.603 ± 0.029	1.791AlaHis: 1.791 ± 0.015	4.271AlaIle: 4.271 ± 0.025	3.627AlaLys: 3.627 ± 0.027	7.644AlaLeu: 7.644 ± 0.034	1.814AlaMet: 1.814 ± 0.015	2.633AlaAsn: 2.633 ± 0.014	4.473AlaPro: 4.473 ± 0.032	2.848AlaGln: 2.848 ± 0.022	4.415AlaArg: 4.415 ± 0.024	6.934AlaSer: 6.934 ± 0.033	4.933AlaThr: 4.933 ± 0.029	5.026AlaVal: 5.026 ± 0.03	1.151AlaTrp: 1.151 ± 0.012	2.158AlaTyr: 2.158 ± 0.016	0.0AlaXaa: 0.0 ± 0.0
Cys	0.974CysAla: 0.974 ± 0.01	0.286CysCys: 0.286 ± 0.006	0.733CysAsp: 0.733 ± 0.01	0.665CysGlu: 0.665 ± 0.008	0.606CysPhe: 0.606 ± 0.009	0.882CysGly: 0.882 ± 0.009	0.451CysHis: 0.451 ± 0.008	0.831CysIle: 0.831 ± 0.01	0.615CysLys: 0.615 ± 0.009	1.44CysLeu: 1.44 ± 0.013	0.324CysMet: 0.324 ± 0.006	0.468CysAsn: 0.468 ± 0.008	0.892CysPro: 0.892 ± 0.012	0.537CysGln: 0.537 ± 0.008	0.875CysArg: 0.875 ± 0.009	1.175CysSer: 1.175 ± 0.012	0.846CysThr: 0.846 ± 0.01	0.84CysVal: 0.84 ± 0.011	0.252CysTrp: 0.252 ± 0.005	0.396CysTyr: 0.396 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	4.612AspAla: 4.612 ± 0.024	0.745AspCys: 0.745 ± 0.01	4.52AspAsp: 4.52 ± 0.028	4.368AspGlu: 4.368 ± 0.029	2.24AspPhe: 2.24 ± 0.015	3.893AspGly: 3.893 ± 0.022	1.423AspHis: 1.423 ± 0.013	3.673AspIle: 3.673 ± 0.022	2.278AspLys: 2.278 ± 0.02	5.302AspLeu: 5.302 ± 0.026	1.267AspMet: 1.267 ± 0.012	1.983AspAsn: 1.983 ± 0.014	3.345AspPro: 3.345 ± 0.021	1.572AspGln: 1.572 ± 0.014	2.862AspArg: 2.862 ± 0.019	4.38AspSer: 4.38 ± 0.026	3.173AspThr: 3.173 ± 0.02	4.187AspVal: 4.187 ± 0.022	0.984AspTrp: 0.984 ± 0.012	1.707AspTyr: 1.707 ± 0.015	0.0AspXaa: 0.0 ± 0.0
Glu	4.603GluAla: 4.603 ± 0.029	0.714GluCys: 0.714 ± 0.009	4.092GluAsp: 4.092 ± 0.028	5.236GluGlu: 5.236 ± 0.043	1.878GluPhe: 1.878 ± 0.015	3.441GluGly: 3.441 ± 0.023	1.505GluHis: 1.505 ± 0.013	3.001GluIle: 3.001 ± 0.02	3.153GluLys: 3.153 ± 0.026	5.322GluLeu: 5.322 ± 0.032	1.423GluMet: 1.423 ± 0.015	1.927GluAsn: 1.927 ± 0.015	2.658GluPro: 2.658 ± 0.02	2.136GluGln: 2.136 ± 0.019	3.806GluArg: 3.806 ± 0.027	4.048GluSer: 4.048 ± 0.023	3.242GluThr: 3.242 ± 0.019	3.461GluVal: 3.461 ± 0.021	1.069GluTrp: 1.069 ± 0.011	1.804GluTyr: 1.804 ± 0.015	0.0GluXaa: 0.0 ± 0.0
Phe	2.882PheAla: 2.882 ± 0.021	0.594PheCys: 0.594 ± 0.009	2.331PheAsp: 2.331 ± 0.016	2.117PheGlu: 2.117 ± 0.016	1.726PhePhe: 1.726 ± 0.016	2.569PheGly: 2.569 ± 0.023	1.076PheHis: 1.076 ± 0.011	2.113PheIle: 2.113 ± 0.017	1.584PheLys: 1.584 ± 0.013	3.788PheLeu: 3.788 ± 0.024	0.862PheMet: 0.862 ± 0.009	1.43PheAsn: 1.43 ± 0.012	2.249PhePro: 2.249 ± 0.017	1.417PheGln: 1.417 ± 0.014	2.202PheArg: 2.202 ± 0.017	3.36PheSer: 3.36 ± 0.021	2.32PheThr: 2.32 ± 0.016	2.576PheVal: 2.576 ± 0.018	0.599PheTrp: 0.599 ± 0.007	1.131PheTyr: 1.131 ± 0.011	0.0PheXaa: 0.0 ± 0.0
Gly	4.276GlyAla: 4.276 ± 0.025	0.937GlyCys: 0.937 ± 0.011	3.345GlyAsp: 3.345 ± 0.02	3.074GlyGlu: 3.074 ± 0.021	2.312GlyPhe: 2.312 ± 0.019	4.494GlyGly: 4.494 ± 0.037	1.727GlyHis: 1.727 ± 0.015	3.379GlyIle: 3.379 ± 0.022	3.075GlyLys: 3.075 ± 0.019	5.272GlyLeu: 5.272 ± 0.027	1.404GlyMet: 1.404 ± 0.016	2.202GlyAsn: 2.202 ± 0.016	3.044GlyPro: 3.044 ± 0.022	2.139GlyGln: 2.139 ± 0.018	3.72GlyArg: 3.72 ± 0.023	5.094GlySer: 5.094 ± 0.032	3.769GlyThr: 3.769 ± 0.026	3.839GlyVal: 3.839 ± 0.024	1.072GlyTrp: 1.072 ± 0.012	1.905GlyTyr: 1.905 ± 0.017	0.0GlyXaa: 0.0 ± 0.0
His	1.959HisAla: 1.959 ± 0.015	0.428HisCys: 0.428 ± 0.007	1.468HisAsp: 1.468 ± 0.013	1.299HisGlu: 1.299 ± 0.011	1.13HisPhe: 1.13 ± 0.012	1.537HisGly: 1.537 ± 0.013	0.957HisHis: 0.957 ± 0.011	1.511HisIle: 1.511 ± 0.013	1.046HisLys: 1.046 ± 0.012	2.67HisLeu: 2.67 ± 0.018	0.506HisMet: 0.506 ± 0.007	0.884HisAsn: 0.884 ± 0.011	1.941HisPro: 1.941 ± 0.015	1.0HisGln: 1.0 ± 0.012	1.711HisArg: 1.711 ± 0.015	2.195HisSer: 2.195 ± 0.019	1.478HisThr: 1.478 ± 0.013	1.648HisVal: 1.648 ± 0.014	0.399HisTrp: 0.399 ± 0.006	0.768HisTyr: 0.768 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.108IleAla: 4.108 ± 0.022	0.806IleCys: 0.806 ± 0.009	3.116IleAsp: 3.116 ± 0.018	2.834IleGlu: 2.834 ± 0.016	2.233IlePhe: 2.233 ± 0.017	2.914IleGly: 2.914 ± 0.021	1.448IleHis: 1.448 ± 0.013	2.949IleIle: 2.949 ± 0.02	2.242IleLys: 2.242 ± 0.019	5.203IleLeu: 5.203 ± 0.03	1.082IleMet: 1.082 ± 0.01	1.825IleAsn: 1.825 ± 0.014	3.7IlePro: 3.7 ± 0.022	1.878IleGln: 1.878 ± 0.016	2.988IleArg: 2.988 ± 0.016	4.434IleSer: 4.434 ± 0.027	3.223IleThr: 3.223 ± 0.02	3.451IleVal: 3.451 ± 0.022	0.788IleTrp: 0.788 ± 0.01	1.512IleTyr: 1.512 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	3.986LysAla: 3.986 ± 0.028	0.559LysCys: 0.559 ± 0.009	2.88LysAsp: 2.88 ± 0.021	3.258LysGlu: 3.258 ± 0.027	1.444LysPhe: 1.444 ± 0.014	2.847LysGly: 2.847 ± 0.019	1.19LysHis: 1.19 ± 0.011	2.161LysIle: 2.161 ± 0.017	3.172LysLys: 3.172 ± 0.032	3.953LysLeu: 3.953 ± 0.024	0.986LysMet: 0.986 ± 0.011	1.59LysAsn: 1.59 ± 0.014	2.5LysPro: 2.5 ± 0.02	1.579LysGln: 1.579 ± 0.015	3.213LysArg: 3.213 ± 0.025	3.196LysSer: 3.196 ± 0.021	2.686LysThr: 2.686 ± 0.019	2.822LysVal: 2.822 ± 0.021	0.732LysTrp: 0.732 ± 0.009	1.354LysTyr: 1.354 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	7.368LeuAla: 7.368 ± 0.034	1.501LeuCys: 1.501 ± 0.015	5.528LeuAsp: 5.528 ± 0.03	5.407LeuGlu: 5.407 ± 0.029	3.601LeuPhe: 3.601 ± 0.023	5.305LeuGly: 5.305 ± 0.028	2.694LeuHis: 2.694 ± 0.018	4.247LeuIle: 4.247 ± 0.025	4.233LeuLys: 4.233 ± 0.024	8.668LeuLeu: 8.668 ± 0.046	1.826LeuMet: 1.826 ± 0.014	3.264LeuAsn: 3.264 ± 0.022	6.427LeuPro: 6.427 ± 0.032	3.807LeuGln: 3.807 ± 0.024	6.16LeuArg: 6.16 ± 0.028	8.301LeuSer: 8.301 ± 0.045	5.33LeuThr: 5.33 ± 0.029	5.772LeuVal: 5.772 ± 0.029	1.33LeuTrp: 1.33 ± 0.014	2.639LeuTyr: 2.639 ± 0.019	0.0LeuXaa: 0.0 ± 0.0
Met	1.841MetAla: 1.841 ± 0.015	0.257MetCys: 0.257 ± 0.005	1.32MetAsp: 1.32 ± 0.012	1.263MetGlu: 1.263 ± 0.012	0.85MetPhe: 0.85 ± 0.011	1.278MetGly: 1.278 ± 0.014	0.552MetHis: 0.552 ± 0.009	1.074MetIle: 1.074 ± 0.011	1.057MetLys: 1.057 ± 0.011	1.928MetLeu: 1.928 ± 0.016	0.538MetMet: 0.538 ± 0.01	0.841MetAsn: 0.841 ± 0.01	1.284MetPro: 1.284 ± 0.011	0.805MetGln: 0.805 ± 0.01	1.168MetArg: 1.168 ± 0.013	2.077MetSer: 2.077 ± 0.016	1.389MetThr: 1.389 ± 0.013	1.306MetVal: 1.306 ± 0.015	0.271MetTrp: 0.271 ± 0.006	0.621MetTyr: 0.621 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	2.919AsnAla: 2.919 ± 0.019	0.432AsnCys: 0.432 ± 0.007	2.095AsnAsp: 2.095 ± 0.016	1.962AsnGlu: 1.962 ± 0.015	1.344AsnPhe: 1.344 ± 0.013	2.481AsnGly: 2.481 ± 0.02	0.897AsnHis: 0.897 ± 0.009	2.094AsnIle: 2.094 ± 0.015	1.368AsnLys: 1.368 ± 0.013	3.202AsnLeu: 3.202 ± 0.022	0.788AsnMet: 0.788 ± 0.01	1.334AsnAsn: 1.334 ± 0.014	2.354AsnPro: 2.354 ± 0.017	1.206AsnGln: 1.206 ± 0.013	1.941AsnArg: 1.941 ± 0.015	2.707AsnSer: 2.707 ± 0.017	2.09AsnThr: 2.09 ± 0.017	2.41AsnVal: 2.41 ± 0.017	0.545AsnTrp: 0.545 ± 0.008	1.015AsnTyr: 1.015 ± 0.01	0.0AsnXaa: 0.0 ± 0.0
Pro	4.735ProAla: 4.735 ± 0.033	0.655ProCys: 0.655 ± 0.009	3.49ProAsp: 3.49 ± 0.019	3.535ProGlu: 3.535 ± 0.02	2.404ProPhe: 2.404 ± 0.019	3.399ProGly: 3.399 ± 0.021	1.521ProHis: 1.521 ± 0.016	2.991ProIle: 2.991 ± 0.02	2.558ProLys: 2.558 ± 0.017	5.411ProLeu: 5.411 ± 0.025	1.144ProMet: 1.144 ± 0.012	2.205ProAsn: 2.205 ± 0.018	6.043ProPro: 6.043 ± 0.061	2.275ProGln: 2.275 ± 0.018	3.523ProArg: 3.523 ± 0.023	6.869ProSer: 6.869 ± 0.046	4.344ProThr: 4.344 ± 0.028	3.972ProVal: 3.972 ± 0.026	0.85ProTrp: 0.85 ± 0.01	1.652ProTyr: 1.652 ± 0.015	0.0ProXaa: 0.0 ± 0.0
Gln	2.999GlnAla: 2.999 ± 0.021	0.593GlnCys: 0.593 ± 0.008	1.904GlnAsp: 1.904 ± 0.014	2.233GlnGlu: 2.233 ± 0.018	1.251GlnPhe: 1.251 ± 0.011	2.053GlnGly: 2.053 ± 0.017	0.955GlnHis: 0.955 ± 0.011	1.7GlnIle: 1.7 ± 0.015	1.732GlnLys: 1.732 ± 0.016	3.201GlnLeu: 3.201 ± 0.023	0.862GlnMet: 0.862 ± 0.012	1.372GlnAsn: 1.372 ± 0.013	2.189GlnPro: 2.189 ± 0.021	1.677GlnGln: 1.677 ± 0.023	2.43GlnArg: 2.43 ± 0.018	2.931GlnSer: 2.931 ± 0.02	2.228GlnThr: 2.228 ± 0.014	2.089GlnVal: 2.089 ± 0.019	0.62GlnTrp: 0.62 ± 0.009	1.196GlnTyr: 1.196 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	4.415ArgAla: 4.415 ± 0.023	0.96ArgCys: 0.96 ± 0.011	3.29ArgAsp: 3.29 ± 0.022	3.422ArgGlu: 3.422 ± 0.027	2.234ArgPhe: 2.234 ± 0.016	3.336ArgGly: 3.336 ± 0.022	1.712ArgHis: 1.712 ± 0.015	3.221ArgIle: 3.221 ± 0.017	3.195ArgLys: 3.195 ± 0.023	5.631ArgLeu: 5.631 ± 0.029	1.402ArgMet: 1.402 ± 0.013	2.168ArgAsn: 2.168 ± 0.016	3.501ArgPro: 3.501 ± 0.023	2.344ArgGln: 2.344 ± 0.018	5.066ArgArg: 5.066 ± 0.035	4.863ArgSer: 4.863 ± 0.032	3.445ArgThr: 3.445 ± 0.02	3.633ArgVal: 3.633 ± 0.022	1.044ArgTrp: 1.044 ± 0.013	1.8ArgTyr: 1.8 ± 0.015	0.0ArgXaa: 0.0 ± 0.0
Ser	6.275SerAla: 6.275 ± 0.032	1.038SerCys: 1.038 ± 0.013	4.756SerAsp: 4.756 ± 0.028	4.13SerGlu: 4.13 ± 0.023	3.354SerPhe: 3.354 ± 0.021	5.059SerGly: 5.059 ± 0.031	2.183SerHis: 2.183 ± 0.018	4.305SerIle: 4.305 ± 0.022	3.673SerLys: 3.673 ± 0.025	8.352SerLeu: 8.352 ± 0.044	1.786SerMet: 1.786 ± 0.015	2.998SerAsn: 2.998 ± 0.019	6.084SerPro: 6.084 ± 0.044	3.083SerGln: 3.083 ± 0.023	5.021SerArg: 5.021 ± 0.031	9.921SerSer: 9.921 ± 0.07	5.966SerThr: 5.966 ± 0.035	5.163SerVal: 5.163 ± 0.026	1.196SerTrp: 1.196 ± 0.01	2.225SerTyr: 2.225 ± 0.015	0.0SerXaa: 0.0 ± 0.0
Thr	4.801ThrAla: 4.801 ± 0.024	0.864ThrCys: 0.864 ± 0.011	3.093ThrAsp: 3.093 ± 0.018	3.055ThrGlu: 3.055 ± 0.02	2.59ThrPhe: 2.59 ± 0.018	3.684ThrGly: 3.684 ± 0.024	1.508ThrHis: 1.508 ± 0.013	3.506ThrIle: 3.506 ± 0.023	2.597ThrLys: 2.597 ± 0.021	5.92ThrLeu: 5.92 ± 0.029	1.261ThrMet: 1.261 ± 0.013	2.109ThrAsn: 2.109 ± 0.017	4.406ThrPro: 4.406 ± 0.03	2.0ThrGln: 2.0 ± 0.015	3.281ThrArg: 3.281 ± 0.021	5.866ThrSer: 5.866 ± 0.032	4.269ThrThr: 4.269 ± 0.027	4.025ThrVal: 4.025 ± 0.022	0.881ThrTrp: 0.881 ± 0.01	1.651ThrTyr: 1.651 ± 0.012	0.0ThrXaa: 0.0 ± 0.0
Val	4.902ValAla: 4.902 ± 0.027	0.947ValCys: 0.947 ± 0.011	3.92ValAsp: 3.92 ± 0.027	3.851ValGlu: 3.851 ± 0.023	2.61ValPhe: 2.61 ± 0.019	3.533ValGly: 3.533 ± 0.023	1.645ValHis: 1.645 ± 0.015	3.346ValIle: 3.346 ± 0.02	2.919ValLys: 2.919 ± 0.019	6.222ValLeu: 6.222 ± 0.03	1.381ValMet: 1.381 ± 0.012	2.187ValAsn: 2.187 ± 0.016	4.12ValPro: 4.12 ± 0.024	2.414ValGln: 2.414 ± 0.015	3.388ValArg: 3.388 ± 0.02	4.897ValSer: 4.897 ± 0.029	3.763ValThr: 3.763 ± 0.023	4.524ValVal: 4.524 ± 0.028	0.971ValTrp: 0.971 ± 0.013	1.928ValTyr: 1.928 ± 0.013	0.0ValXaa: 0.0 ± 0.0
Trp	1.086TrpAla: 1.086 ± 0.01	0.262TrpCys: 0.262 ± 0.005	0.978TrpAsp: 0.978 ± 0.011	0.879TrpGlu: 0.879 ± 0.011	0.593TrpPhe: 0.593 ± 0.009	0.896TrpGly: 0.896 ± 0.011	0.381TrpHis: 0.381 ± 0.007	0.817TrpIle: 0.817 ± 0.011	0.898TrpLys: 0.898 ± 0.01	1.433TrpLeu: 1.433 ± 0.014	0.422TrpMet: 0.422 ± 0.007	0.644TrpAsn: 0.644 ± 0.009	0.676TrpPro: 0.676 ± 0.008	0.503TrpGln: 0.503 ± 0.007	1.097TrpArg: 1.097 ± 0.013	1.129TrpSer: 1.129 ± 0.011	1.122TrpThr: 1.122 ± 0.014	0.952TrpVal: 0.952 ± 0.012	0.341TrpTrp: 0.341 ± 0.007	0.465TrpTyr: 0.465 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.159TyrAla: 2.159 ± 0.016	0.427TyrCys: 0.427 ± 0.007	1.787TyrAsp: 1.787 ± 0.013	1.534TyrGlu: 1.534 ± 0.014	1.297TyrPhe: 1.297 ± 0.013	1.876TyrGly: 1.876 ± 0.018	0.919TyrHis: 0.919 ± 0.01	1.546TyrIle: 1.546 ± 0.014	1.085TyrLys: 1.085 ± 0.011	2.846TyrLeu: 2.846 ± 0.019	0.639TyrMet: 0.639 ± 0.009	1.123TyrAsn: 1.123 ± 0.013	1.691TyrPro: 1.691 ± 0.015	0.994TyrGln: 0.994 ± 0.012	1.814TyrArg: 1.814 ± 0.013	2.191TyrSer: 2.191 ± 0.017	1.752TyrThr: 1.752 ± 0.016	1.771TyrVal: 1.771 ± 0.016	0.479TyrTrp: 0.479 ± 0.007	0.916TyrTyr: 0.916 ± 0.011	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 22192 proteins (9048897 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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