Exophiala xenobiotica

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Fungi; Dikarya; Ascomycota; saccharomyceta; Pezizomycotina; leotiomyceta; Eurotiomycetes; Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala

Average proteome isoelectric point is 6.52

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 12773 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A0D2BHL1|A0A0D2BHL1_9EURO FAD_binding_3 domain-containing protein OS=Exophiala xenobiotica OX=348802 GN=PV05_10457 PE=4 SV=1
MM1 pKa = 7.48HH2 pKa = 7.13SLAVVLAVSALASISLAKK20 pKa = 9.64PIPVPGTSVNTKK32 pKa = 10.16KK33 pKa = 10.84GFTVNQGPAKK43 pKa = 9.51PFQPGPVQLQKK54 pKa = 11.03VYY56 pKa = 11.03SKK58 pKa = 11.23YY59 pKa = 11.08NKK61 pKa = 9.6LAPADD66 pKa = 3.75VSNAAAADD74 pKa = 4.03GSVTATPEE82 pKa = 4.18QYY84 pKa = 10.7DD85 pKa = 3.78SEE87 pKa = 4.5YY88 pKa = 10.61LSPVTIGGQTLNLDD102 pKa = 4.16FDD104 pKa = 4.24TGSADD109 pKa = 2.96LWVFSSEE116 pKa = 4.3LPSSQSSGHH125 pKa = 6.16SIYY128 pKa = 10.94NPSKK132 pKa = 10.61SSTAKK137 pKa = 10.3KK138 pKa = 10.4LSGATWDD145 pKa = 3.19ISYY148 pKa = 11.15GDD150 pKa = 3.82GSGASGDD157 pKa = 4.08VYY159 pKa = 11.04TDD161 pKa = 3.4TVDD164 pKa = 3.25VGGTTVTGQAVEE176 pKa = 3.99LAKK179 pKa = 10.23TISAQFQQDD188 pKa = 3.52QNNDD192 pKa = 3.35GLLGLAFSSINTVTPKK208 pKa = 10.25QQTTFFDD215 pKa = 3.8TAIHH219 pKa = 6.22EE220 pKa = 4.72GVLDD224 pKa = 4.16ANVFTVDD231 pKa = 4.2LKK233 pKa = 11.14KK234 pKa = 10.62GAPGSYY240 pKa = 10.59DD241 pKa = 3.18FGFIDD246 pKa = 3.9DD247 pKa = 4.01SKK249 pKa = 9.02YY250 pKa = 9.54TGEE253 pKa = 3.82ITYY256 pKa = 8.63TAVNSANGFWEE267 pKa = 4.54FTGTGYY273 pKa = 11.27GVGDD277 pKa = 4.01GSFQSSSIDD286 pKa = 3.72AIADD290 pKa = 3.48TGTTLILIDD299 pKa = 4.66DD300 pKa = 5.7DD301 pKa = 4.23IVSAYY306 pKa = 10.05YY307 pKa = 10.73DD308 pKa = 3.75EE309 pKa = 5.46VDD311 pKa = 3.14GAQYY315 pKa = 11.36DD316 pKa = 4.02NSQGGYY322 pKa = 8.2TFDD325 pKa = 4.1CTATLPDD332 pKa = 5.42FILGVEE338 pKa = 4.38DD339 pKa = 4.11AQFTVPGSFINFAPITDD356 pKa = 4.24GSSTCYY362 pKa = 10.55GGIQSNEE369 pKa = 3.64GLGLSIYY376 pKa = 11.02GDD378 pKa = 3.66VFLKK382 pKa = 10.83AVFAIFDD389 pKa = 3.74SDD391 pKa = 3.44NTQLGFANKK400 pKa = 10.13DD401 pKa = 3.29LL402 pKa = 4.31

Molecular weight: 42.06 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A0D2ENP2|A0A0D2ENP2_9EURO Uncharacterized protein OS=Exophiala xenobiotica OX=348802 GN=PV05_05675 PE=4 SV=1
MM1 pKa = 7.32YY2 pKa = 9.38PPRR5 pKa = 11.84WKK7 pKa = 9.26TSPRR11 pKa = 11.84RR12 pKa = 11.84EE13 pKa = 4.03EE14 pKa = 4.05PVLCTTFTVTTTIVSTTTTIHH35 pKa = 7.28DD36 pKa = 4.51EE37 pKa = 4.03RR38 pKa = 11.84LLWPDD43 pKa = 2.84IRR45 pKa = 11.84TKK47 pKa = 10.89GKK49 pKa = 9.04WPSAQSSSSSDD60 pKa = 2.89KK61 pKa = 10.86RR62 pKa = 11.84NPRR65 pKa = 11.84LTQVGRR71 pKa = 11.84SKK73 pKa = 10.0TKK75 pKa = 10.27IRR77 pKa = 11.84WSPDD81 pKa = 2.66KK82 pKa = 10.85SSLMAFQRR90 pKa = 11.84TAMKK94 pKa = 10.83AEE96 pKa = 4.05TQRR99 pKa = 11.84PKK101 pKa = 10.89SLEE104 pKa = 3.88TTTCSRR110 pKa = 11.84NQKK113 pKa = 7.88TCYY116 pKa = 9.75LCCFLHH122 pKa = 7.68RR123 pKa = 11.84IRR125 pKa = 11.84PHH127 pKa = 6.04YY128 pKa = 9.59GRR130 pKa = 11.84KK131 pKa = 9.29SDD133 pKa = 4.69LGRR136 pKa = 11.84SGQGVCHH143 pKa = 6.05EE144 pKa = 4.53EE145 pKa = 3.88KK146 pKa = 10.85VYY148 pKa = 10.79APSLINVYY156 pKa = 9.44TNLSIFVLFCVRR168 pKa = 11.84SSIINLANTPLALGHH183 pKa = 6.48RR184 pKa = 11.84CRR186 pKa = 11.84SRR188 pKa = 11.84QTFRR192 pKa = 11.84PLRR195 pKa = 11.84VPRR198 pKa = 11.84MGVVGVLRR206 pKa = 11.84RR207 pKa = 11.84PPCSPPPPPPPPVGCPPRR225 pKa = 11.84TPQPLVVQASDD236 pKa = 3.39HH237 pKa = 6.13RR238 pKa = 11.84CRR240 pKa = 11.84PASGHH245 pKa = 6.06SVTTFNTSMASTMPLRR261 pKa = 11.84CSEE264 pKa = 4.24LL265 pKa = 3.47

Molecular weight: 29.82 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

12019

754

12773

6285281

49

5762

492.1

54.5

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

8.602 ± 0.016

1.246 ± 0.008

5.701 ± 0.014

6.048 ± 0.019

3.726 ± 0.013

6.83 ± 0.019

2.465 ± 0.008

4.837 ± 0.013

4.791 ± 0.02

8.876 ± 0.022

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.26 ± 0.008

3.599 ± 0.011

6.03 ± 0.021

4.166 ± 0.015

6.159 ± 0.018

8.214 ± 0.026

6.062 ± 0.015

6.121 ± 0.013

1.477 ± 0.007

2.789 ± 0.01
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski