Lake Sinai virus 1

Taxonomy: Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Magsaviricetes; Nodamuvirales; Sinhaliviridae; Sinaivirus

Average proteome isoelectric point is 7.85

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 3 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A223DND2|A0A223DND2_9VIRU ORF1 OS=Lake Sinai virus 1 OX=1041806 PE=4 SV=1
MM1 pKa = 7.22VKK3 pKa = 10.19LAFAAFVSLYY13 pKa = 9.81IICQVPPISYY23 pKa = 9.27WIEE26 pKa = 4.08DD27 pKa = 3.82LVDD30 pKa = 5.59DD31 pKa = 5.07FDD33 pKa = 4.45TMCSYY38 pKa = 10.99EE39 pKa = 4.2YY40 pKa = 10.97AAADD44 pKa = 3.72AYY46 pKa = 11.33NSFVHH51 pKa = 5.57RR52 pKa = 11.84HH53 pKa = 4.7RR54 pKa = 11.84VAAYY58 pKa = 7.79AAGVRR63 pKa = 11.84IHH65 pKa = 7.65RR66 pKa = 11.84YY67 pKa = 5.68RR68 pKa = 11.84TPWYY72 pKa = 8.6CAVSRR77 pKa = 11.84SVPVVHH83 pKa = 6.81PLNWLMSQYY92 pKa = 11.44DD93 pKa = 4.11LTTGHH98 pKa = 6.06VRR100 pKa = 11.84EE101 pKa = 4.25LLDD104 pKa = 3.46RR105 pKa = 11.84LEE107 pKa = 4.35VVNVTLRR114 pKa = 11.84DD115 pKa = 3.71GLRR118 pKa = 11.84TVADD122 pKa = 3.88TAFTAYY128 pKa = 9.15MYY130 pKa = 9.54YY131 pKa = 10.52QIMWCQLALIVLLVGLFSAIICSSRR156 pKa = 11.84VRR158 pKa = 11.84VVRR161 pKa = 11.84VRR163 pKa = 11.84NRR165 pKa = 11.84VRR167 pKa = 11.84GYY169 pKa = 10.82SIADD173 pKa = 3.33LRR175 pKa = 11.84NEE177 pKa = 4.05FDD179 pKa = 3.98EE180 pKa = 4.5STSDD184 pKa = 2.77ITLPLSRR191 pKa = 11.84GHH193 pKa = 6.26SCLNFQRR200 pKa = 11.84RR201 pKa = 11.84VAEE204 pKa = 4.46SWCLDD209 pKa = 3.05QLLRR213 pKa = 11.84YY214 pKa = 8.35FHH216 pKa = 6.84GLRR219 pKa = 11.84FVSASRR225 pKa = 11.84GRR227 pKa = 11.84WAEE230 pKa = 3.79LGHH233 pKa = 6.59RR234 pKa = 11.84IHH236 pKa = 6.68WCSPVVMDD244 pKa = 5.27GSFVPEE250 pKa = 4.14ATHH253 pKa = 7.04HH254 pKa = 6.23GVLCRR259 pKa = 11.84RR260 pKa = 11.84QPSACRR266 pKa = 11.84DD267 pKa = 3.37RR268 pKa = 11.84FEE270 pKa = 5.7IPACVISHH278 pKa = 7.15ADD280 pKa = 3.45YY281 pKa = 11.6YY282 pKa = 10.79MSPDD286 pKa = 3.42QLASTVTGPTFIINHH301 pKa = 7.3DD302 pKa = 3.91YY303 pKa = 10.82LAPDD307 pKa = 3.65SLSVAEE313 pKa = 4.14ATTRR317 pKa = 11.84VANGHH322 pKa = 4.7VTSSVRR328 pKa = 11.84EE329 pKa = 3.93GPIYY333 pKa = 10.54GPHH336 pKa = 7.62PYY338 pKa = 10.43YY339 pKa = 10.67LWNNEE344 pKa = 3.77GVVVSSTGAFRR355 pKa = 11.84YY356 pKa = 9.8YY357 pKa = 10.32RR358 pKa = 11.84VGRR361 pKa = 11.84LFDD364 pKa = 3.32TSVYY368 pKa = 10.45YY369 pKa = 10.78AFPAAGTYY377 pKa = 10.45SCDD380 pKa = 3.38DD381 pKa = 3.47PTNLRR386 pKa = 11.84RR387 pKa = 11.84STVGDD392 pKa = 2.97LHH394 pKa = 7.11YY395 pKa = 10.81YY396 pKa = 9.91SPHH399 pKa = 5.45EE400 pKa = 4.31KK401 pKa = 10.65KK402 pKa = 10.42FVSYY406 pKa = 10.82SADD409 pKa = 3.14DD410 pKa = 3.53TNYY413 pKa = 10.28HH414 pKa = 5.49VFGTSVPRR422 pKa = 11.84SLADD426 pKa = 3.09YY427 pKa = 10.3CAATFCRR434 pKa = 11.84SARR437 pKa = 11.84DD438 pKa = 3.5DD439 pKa = 3.37KK440 pKa = 11.37FYY442 pKa = 11.37DD443 pKa = 3.63GLRR446 pKa = 11.84SYY448 pKa = 9.94YY449 pKa = 8.94QNRR452 pKa = 11.84CRR454 pKa = 11.84AIGFNDD460 pKa = 3.62ARR462 pKa = 11.84DD463 pKa = 3.73TLILDD468 pKa = 4.81FIIHH472 pKa = 6.66LCDD475 pKa = 3.16EE476 pKa = 4.87ASLKK480 pKa = 10.08TFGFSRR486 pKa = 11.84LSVAPSSWTAYY497 pKa = 8.92CLSWFLVKK505 pKa = 10.3VNHH508 pKa = 5.79MMPLALTSFVVSALHH523 pKa = 6.37RR524 pKa = 11.84FFGARR529 pKa = 11.84SAPWNWASIHH539 pKa = 6.35LPTYY543 pKa = 11.51DD544 pKa = 3.08MVTSPFRR551 pKa = 11.84LRR553 pKa = 11.84MFGRR557 pKa = 11.84NPTTFNLEE565 pKa = 3.78RR566 pKa = 11.84FRR568 pKa = 11.84AEE570 pKa = 3.6ASTVGAPSPGQSAEE584 pKa = 4.15GAGEE588 pKa = 4.2NGDD591 pKa = 3.43QHH593 pKa = 6.75DD594 pKa = 4.76FKK596 pKa = 11.16LGDD599 pKa = 3.87PSPPPSSVPSLSSGDD614 pKa = 3.9SIEE617 pKa = 5.35ASDD620 pKa = 5.58HH621 pKa = 6.54LLFDD625 pKa = 3.62NRR627 pKa = 11.84SRR629 pKa = 11.84PASVDD634 pKa = 3.2SRR636 pKa = 11.84STNTQASRR644 pKa = 11.84SSGILSNKK652 pKa = 9.07GKK654 pKa = 7.9TRR656 pKa = 11.84RR657 pKa = 11.84KK658 pKa = 7.85SHH660 pKa = 6.55RR661 pKa = 11.84PSHH664 pKa = 6.84DD665 pKa = 3.33NSDD668 pKa = 3.69TDD670 pKa = 3.55HH671 pKa = 6.29GHH673 pKa = 5.69SVCHH677 pKa = 6.3PKK679 pKa = 9.35RR680 pKa = 11.84TTYY683 pKa = 10.01PLCPDD688 pKa = 3.82PTASCGPHH696 pKa = 6.48FFMSVCEE703 pKa = 4.29HH704 pKa = 7.27DD705 pKa = 3.87EE706 pKa = 4.06STPTVFHH713 pKa = 6.27AHH715 pKa = 5.53SVGGQDD721 pKa = 2.71ITHH724 pKa = 7.46DD725 pKa = 3.58IDD727 pKa = 4.24SGLGAIISKK736 pKa = 10.21RR737 pKa = 11.84FSASQLRR744 pKa = 11.84LLSWSIDD751 pKa = 3.77GIFNTLSRR759 pKa = 11.84AATSSFVEE767 pKa = 4.23SSLLSLLRR775 pKa = 11.84FMQQVPAVEE784 pKa = 4.69SSAEE788 pKa = 3.94TRR790 pKa = 11.84RR791 pKa = 11.84CLLFGGPRR799 pKa = 11.84EE800 pKa = 4.0RR801 pKa = 11.84FKK803 pKa = 11.29GYY805 pKa = 8.65DD806 pKa = 3.25TFDD809 pKa = 3.48LGFMGVAVPSDD820 pKa = 3.29KK821 pKa = 10.98TKK823 pKa = 11.05GIEE826 pKa = 3.68ACLRR830 pKa = 11.84EE831 pKa = 4.61VARR834 pKa = 11.84QHH836 pKa = 6.16ARR838 pKa = 11.84ADD840 pKa = 4.06GPHH843 pKa = 6.54EE844 pKa = 4.29GAA846 pKa = 4.97

Molecular weight: 94.63 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A223DND2|A0A223DND2_9VIRU ORF1 OS=Lake Sinai virus 1 OX=1041806 PE=4 SV=1
MM1 pKa = 7.62NSICSLYY8 pKa = 10.41CLFRR12 pKa = 11.84RR13 pKa = 11.84VMPYY17 pKa = 10.04SSEE20 pKa = 3.91ILSSTVYY27 pKa = 10.36RR28 pKa = 11.84PPFLATSGLFFTRR41 pKa = 11.84DD42 pKa = 3.02HH43 pKa = 6.51YY44 pKa = 11.74KK45 pKa = 10.53FIIMNQQQINPAQRR59 pKa = 11.84SLRR62 pKa = 11.84PRR64 pKa = 11.84AQSAPSRR71 pKa = 11.84SARR74 pKa = 11.84RR75 pKa = 11.84RR76 pKa = 11.84RR77 pKa = 11.84NRR79 pKa = 11.84RR80 pKa = 11.84RR81 pKa = 11.84RR82 pKa = 11.84NPSTPAGTVALQPSRR97 pKa = 11.84ITRR100 pKa = 11.84RR101 pKa = 11.84VVSNLARR108 pKa = 11.84RR109 pKa = 11.84PLTITTAGLAWLRR122 pKa = 11.84QYY124 pKa = 10.73LNPMGPSTSSVSGFPDD140 pKa = 4.21GSAVTTCIADD150 pKa = 3.42YY151 pKa = 10.65TNTFNISFPPRR162 pKa = 11.84EE163 pKa = 4.35AIYY166 pKa = 8.75CTGSNSDD173 pKa = 4.34EE174 pKa = 4.53KK175 pKa = 11.07PVMLDD180 pKa = 2.64AATYY184 pKa = 10.74AKK186 pKa = 9.82IDD188 pKa = 3.17AWTKK192 pKa = 11.14SDD194 pKa = 3.05ITLCILALPMLRR206 pKa = 11.84NVVMIRR212 pKa = 11.84LYY214 pKa = 11.13ASTPTAFTLSEE225 pKa = 4.13GVPNFVQRR233 pKa = 11.84FPNWSAFTTEE243 pKa = 4.71GKK245 pKa = 10.08VLNNGDD251 pKa = 3.87SPGYY255 pKa = 8.94IQSFVYY261 pKa = 10.27LPNVDD266 pKa = 3.44KK267 pKa = 10.99HH268 pKa = 6.88LSAARR273 pKa = 11.84GFRR276 pKa = 11.84LLSRR280 pKa = 11.84GLTGIYY286 pKa = 7.6TAPSLEE292 pKa = 4.14TQGFVTACQYY302 pKa = 10.63LAEE305 pKa = 5.07GALQTQTVGNDD316 pKa = 3.14FVQSVEE322 pKa = 4.04VNADD326 pKa = 3.36KK327 pKa = 10.48TVKK330 pKa = 10.19NVNGKK335 pKa = 8.9RR336 pKa = 11.84LHH338 pKa = 6.1YY339 pKa = 10.26SGPPKK344 pKa = 10.27FVFPLEE350 pKa = 4.4GDD352 pKa = 3.21NCAPSSLVEE361 pKa = 4.57TYY363 pKa = 10.02HH364 pKa = 6.01QAYY367 pKa = 8.56QARR370 pKa = 11.84AVDD373 pKa = 4.32GFYY376 pKa = 10.38MPILSSSRR384 pKa = 11.84DD385 pKa = 3.49NPFISPKK392 pKa = 8.23PQPIAVFNRR401 pKa = 11.84WYY403 pKa = 10.87YY404 pKa = 10.41RR405 pKa = 11.84GCLDD409 pKa = 4.21PVPASKK415 pKa = 10.89VADD418 pKa = 4.31GPSQYY423 pKa = 11.31YY424 pKa = 10.24YY425 pKa = 10.95DD426 pKa = 5.38LNVADD431 pKa = 5.91DD432 pKa = 3.95VAPLYY437 pKa = 9.08NTGVVWMEE445 pKa = 4.42GISSKK450 pKa = 10.59FSLKK454 pKa = 10.67LKK456 pKa = 9.1TRR458 pKa = 11.84TVIQYY463 pKa = 9.27IPTSGSVLANFTRR476 pKa = 11.84HH477 pKa = 5.56EE478 pKa = 3.97PTYY481 pKa = 11.07DD482 pKa = 3.53QVALDD487 pKa = 3.47AADD490 pKa = 5.36RR491 pKa = 11.84IRR493 pKa = 11.84NMMPHH498 pKa = 7.84AYY500 pKa = 8.55PAAYY504 pKa = 9.97NDD506 pKa = 3.89WGWLGDD512 pKa = 4.28LLDD515 pKa = 4.5STLSMLPGIGTAYY528 pKa = 10.55RR529 pKa = 11.84FAKK532 pKa = 10.21PLIKK536 pKa = 9.98PAWNWLGGKK545 pKa = 9.81VSDD548 pKa = 4.29FFGNPVSRR556 pKa = 11.84DD557 pKa = 2.59GDD559 pKa = 3.47IYY561 pKa = 11.22FDD563 pKa = 3.68AKK565 pKa = 10.97

Molecular weight: 62.91 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

3

0

3

2033

565

846

677.7

75.85

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.772 ± 0.553

2.607 ± 0.485

5.558 ± 0.388

3.099 ± 0.368

4.427 ± 0.566

5.411 ± 0.454

2.902 ± 0.773

4.427 ± 0.378

2.656 ± 0.421

9.641 ± 1.354

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.918 ± 0.125

3.492 ± 0.684

6.69 ± 0.654

2.656 ± 0.371

7.624 ± 0.312

9.838 ± 0.557

6.542 ± 0.354

6.591 ± 0.449

1.426 ± 0.112

4.722 ± 0.185
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski