Amino acid dipepetide frequency for Allomyces macrogynus (strain ATCC 38327) (Allomyces javanicus var. macrogynus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	23.027AlaAla: 23.027 ± 0.105	1.274AlaCys: 1.274 ± 0.014	6.615AlaAsp: 6.615 ± 0.032	5.51AlaGlu: 5.51 ± 0.041	3.192AlaPhe: 3.192 ± 0.022	7.654AlaGly: 7.654 ± 0.035	3.513AlaHis: 3.513 ± 0.025	4.192AlaIle: 4.192 ± 0.027	4.548AlaLys: 4.548 ± 0.028	11.152AlaLeu: 11.152 ± 0.05	3.113AlaMet: 3.113 ± 0.021	3.192AlaAsn: 3.192 ± 0.02	10.616AlaPro: 10.616 ± 0.067	4.588AlaGln: 4.588 ± 0.032	8.482AlaArg: 8.482 ± 0.044	9.843AlaSer: 9.843 ± 0.046	9.231AlaThr: 9.231 ± 0.042	9.685AlaVal: 9.685 ± 0.044	1.545AlaTrp: 1.545 ± 0.017	2.15AlaTyr: 2.15 ± 0.014	0.0AlaXaa: 0.0 ± 0.0
Cys	1.241CysAla: 1.241 ± 0.014	0.23CysCys: 0.23 ± 0.006	0.593CysAsp: 0.593 ± 0.009	0.425CysGlu: 0.425 ± 0.008	0.398CysPhe: 0.398 ± 0.007	0.84CysGly: 0.84 ± 0.012	0.331CysHis: 0.331 ± 0.006	0.507CysIle: 0.507 ± 0.008	0.387CysLys: 0.387 ± 0.007	1.069CysLeu: 1.069 ± 0.013	0.278CysMet: 0.278 ± 0.006	0.337CysAsn: 0.337 ± 0.006	0.718CysPro: 0.718 ± 0.011	0.334CysGln: 0.334 ± 0.006	0.766CysArg: 0.766 ± 0.01	0.712CysSer: 0.712 ± 0.01	0.75CysThr: 0.75 ± 0.01	0.828CysVal: 0.828 ± 0.01	0.14CysTrp: 0.14 ± 0.004	0.26CysTyr: 0.26 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	7.957AspAla: 7.957 ± 0.037	0.481AspCys: 0.481 ± 0.008	5.235AspAsp: 5.235 ± 0.049	4.144AspGlu: 4.144 ± 0.034	1.59AspPhe: 1.59 ± 0.013	3.793AspGly: 3.793 ± 0.024	1.537AspHis: 1.537 ± 0.015	1.632AspIle: 1.632 ± 0.016	1.905AspLys: 1.905 ± 0.019	5.854AspLeu: 5.854 ± 0.033	1.38AspMet: 1.38 ± 0.013	1.202AspAsn: 1.202 ± 0.012	3.955AspPro: 3.955 ± 0.022	1.976AspGln: 1.976 ± 0.016	3.56AspArg: 3.56 ± 0.027	3.046AspSer: 3.046 ± 0.024	2.679AspThr: 2.679 ± 0.016	4.634AspVal: 4.634 ± 0.024	0.752AspTrp: 0.752 ± 0.011	1.109AspTyr: 1.109 ± 0.012	0.0AspXaa: 0.0 ± 0.0
Glu	4.73GluAla: 4.73 ± 0.035	0.562GluCys: 0.562 ± 0.009	2.957GluAsp: 2.957 ± 0.025	3.148GluGlu: 3.148 ± 0.031	1.593GluPhe: 1.593 ± 0.016	2.287GluGly: 2.287 ± 0.018	1.285GluHis: 1.285 ± 0.012	1.894GluIle: 1.894 ± 0.021	1.838GluLys: 1.838 ± 0.02	4.596GluLeu: 4.596 ± 0.03	1.302GluMet: 1.302 ± 0.013	1.276GluAsn: 1.276 ± 0.011	2.626GluPro: 2.626 ± 0.026	1.883GluGln: 1.883 ± 0.019	3.223GluArg: 3.223 ± 0.028	3.078GluSer: 3.078 ± 0.022	2.71GluThr: 2.71 ± 0.019	3.093GluVal: 3.093 ± 0.021	0.741GluTrp: 0.741 ± 0.009	1.361GluTyr: 1.361 ± 0.013	0.0GluXaa: 0.0 ± 0.0
Phe	3.445PheAla: 3.445 ± 0.021	0.418PheCys: 0.418 ± 0.007	1.973PheAsp: 1.973 ± 0.017	1.443PheGlu: 1.443 ± 0.013	1.158PhePhe: 1.158 ± 0.014	2.187PheGly: 2.187 ± 0.022	0.823PheHis: 0.823 ± 0.01	1.063PheIle: 1.063 ± 0.013	1.085PheLys: 1.085 ± 0.015	3.03PheLeu: 3.03 ± 0.022	0.706PheMet: 0.706 ± 0.009	0.889PheAsn: 0.889 ± 0.011	1.763PhePro: 1.763 ± 0.016	1.073PheGln: 1.073 ± 0.012	1.731PheArg: 1.731 ± 0.014	1.921PheSer: 1.921 ± 0.017	1.73PheThr: 1.73 ± 0.017	2.302PheVal: 2.302 ± 0.018	0.395PheTrp: 0.395 ± 0.006	0.787PheTyr: 0.787 ± 0.011	0.0PheXaa: 0.0 ± 0.0
Gly	7.391GlyAla: 7.391 ± 0.039	0.693GlyCys: 0.693 ± 0.009	3.449GlyAsp: 3.449 ± 0.022	2.72GlyGlu: 2.72 ± 0.019	1.93GlyPhe: 1.93 ± 0.018	5.786GlyGly: 5.786 ± 0.044	1.794GlyHis: 1.794 ± 0.017	2.417GlyIle: 2.417 ± 0.02	2.725GlyLys: 2.725 ± 0.021	4.81GlyLeu: 4.81 ± 0.027	1.669GlyMet: 1.669 ± 0.016	1.882GlyAsn: 1.882 ± 0.017	3.487GlyPro: 3.487 ± 0.024	1.936GlyGln: 1.936 ± 0.016	3.659GlyArg: 3.659 ± 0.022	5.236GlySer: 5.236 ± 0.033	4.385GlyThr: 4.385 ± 0.028	4.269GlyVal: 4.269 ± 0.026	0.793GlyTrp: 0.793 ± 0.01	1.502GlyTyr: 1.502 ± 0.015	0.0GlyXaa: 0.0 ± 0.0
His	3.747HisAla: 3.747 ± 0.028	0.311HisCys: 0.311 ± 0.005	1.869HisAsp: 1.869 ± 0.018	1.25HisGlu: 1.25 ± 0.014	0.851HisPhe: 0.851 ± 0.01	1.99HisGly: 1.99 ± 0.02	1.331HisHis: 1.331 ± 0.022	0.842HisIle: 0.842 ± 0.012	0.709HisLys: 0.709 ± 0.009	2.803HisLeu: 2.803 ± 0.021	0.544HisMet: 0.544 ± 0.008	0.564HisAsn: 0.564 ± 0.007	1.85HisPro: 1.85 ± 0.017	1.047HisGln: 1.047 ± 0.013	1.811HisArg: 1.811 ± 0.015	1.383HisSer: 1.383 ± 0.014	1.172HisThr: 1.172 ± 0.011	2.431HisVal: 2.431 ± 0.017	0.332HisTrp: 0.332 ± 0.007	0.589HisTyr: 0.589 ± 0.008	0.0HisXaa: 0.0 ± 0.0
Ile	4.161IleAla: 4.161 ± 0.024	0.416IleCys: 0.416 ± 0.007	2.37IleAsp: 2.37 ± 0.017	1.928IleGlu: 1.928 ± 0.016	1.088IlePhe: 1.088 ± 0.013	2.093IleGly: 2.093 ± 0.017	0.884IleHis: 0.884 ± 0.009	1.283IleIle: 1.283 ± 0.016	1.626IleLys: 1.626 ± 0.015	3.214IleLeu: 3.214 ± 0.021	0.846IleMet: 0.846 ± 0.011	1.096IleAsn: 1.096 ± 0.013	2.323IlePro: 2.323 ± 0.015	1.289IleGln: 1.289 ± 0.013	2.012IleArg: 2.012 ± 0.017	2.102IleSer: 2.102 ± 0.018	2.089IleThr: 2.089 ± 0.016	2.892IleVal: 2.892 ± 0.023	0.4IleTrp: 0.4 ± 0.007	0.826IleTyr: 0.826 ± 0.01	0.0IleXaa: 0.0 ± 0.0
Lys	3.565LysAla: 3.565 ± 0.029	0.483LysCys: 0.483 ± 0.009	2.022LysAsp: 2.022 ± 0.019	1.791LysGlu: 1.791 ± 0.02	1.043LysPhe: 1.043 ± 0.013	1.89LysGly: 1.89 ± 0.017	0.912LysHis: 0.912 ± 0.009	1.431LysIle: 1.431 ± 0.016	2.175LysLys: 2.175 ± 0.028	3.417LysLeu: 3.417 ± 0.023	0.801LysMet: 0.801 ± 0.01	1.039LysAsn: 1.039 ± 0.013	2.145LysPro: 2.145 ± 0.02	1.345LysGln: 1.345 ± 0.015	2.709LysArg: 2.709 ± 0.02	2.493LysSer: 2.493 ± 0.019	2.048LysThr: 2.048 ± 0.018	2.462LysVal: 2.462 ± 0.02	0.523LysTrp: 0.523 ± 0.008	1.043LysTyr: 1.043 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	12.511LeuAla: 12.511 ± 0.053	1.127LeuCys: 1.127 ± 0.012	5.938LeuAsp: 5.938 ± 0.033	4.353LeuGlu: 4.353 ± 0.034	3.073LeuPhe: 3.073 ± 0.021	5.362LeuGly: 5.362 ± 0.03	2.705LeuHis: 2.705 ± 0.018	3.118LeuIle: 3.118 ± 0.02	3.078LeuLys: 3.078 ± 0.025	8.633LeuLeu: 8.633 ± 0.044	1.823LeuMet: 1.823 ± 0.015	2.353LeuAsn: 2.353 ± 0.018	6.23LeuPro: 6.23 ± 0.035	3.332LeuGln: 3.332 ± 0.024	5.847LeuArg: 5.847 ± 0.032	5.602LeuSer: 5.602 ± 0.028	5.211LeuThr: 5.211 ± 0.028	7.576LeuVal: 7.576 ± 0.044	0.969LeuTrp: 0.969 ± 0.011	1.97LeuTyr: 1.97 ± 0.014	0.0LeuXaa: 0.0 ± 0.0
Met	3.032MetAla: 3.032 ± 0.018	0.266MetCys: 0.266 ± 0.006	1.428MetAsp: 1.428 ± 0.013	0.92MetGlu: 0.92 ± 0.01	0.713MetPhe: 0.713 ± 0.01	1.373MetGly: 1.373 ± 0.015	0.706MetHis: 0.706 ± 0.009	0.804MetIle: 0.804 ± 0.01	0.61MetLys: 0.61 ± 0.009	2.026MetLeu: 2.026 ± 0.016	0.588MetMet: 0.588 ± 0.011	0.604MetAsn: 0.604 ± 0.01	1.697MetPro: 1.697 ± 0.017	0.896MetGln: 0.896 ± 0.011	1.441MetArg: 1.441 ± 0.013	1.785MetSer: 1.785 ± 0.016	1.58MetThr: 1.58 ± 0.014	1.626MetVal: 1.626 ± 0.012	0.265MetTrp: 0.265 ± 0.006	0.536MetTyr: 0.536 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	3.139AsnAla: 3.139 ± 0.018	0.289AsnCys: 0.289 ± 0.006	1.656AsnAsp: 1.656 ± 0.013	1.299AsnGlu: 1.299 ± 0.012	0.742AsnPhe: 0.742 ± 0.01	2.144AsnGly: 2.144 ± 0.019	0.611AsnHis: 0.611 ± 0.008	0.911AsnIle: 0.911 ± 0.011	1.019AsnLys: 1.019 ± 0.014	2.479AsnLeu: 2.479 ± 0.019	0.613AsnMet: 0.613 ± 0.009	0.79AsnAsn: 0.79 ± 0.009	1.764AsnPro: 1.764 ± 0.015	0.913AsnGln: 0.913 ± 0.014	1.366AsnArg: 1.366 ± 0.011	1.525AsnSer: 1.525 ± 0.015	1.374AsnThr: 1.374 ± 0.013	2.241AsnVal: 2.241 ± 0.016	0.328AsnTrp: 0.328 ± 0.007	0.593AsnTyr: 0.593 ± 0.009	0.0AsnXaa: 0.0 ± 0.0
Pro	11.352ProAla: 11.352 ± 0.068	0.626ProCys: 0.626 ± 0.01	3.445ProAsp: 3.445 ± 0.021	2.755ProGlu: 2.755 ± 0.02	1.793ProPhe: 1.793 ± 0.017	4.116ProGly: 4.116 ± 0.028	1.755ProHis: 1.755 ± 0.017	2.239ProIle: 2.239 ± 0.017	1.975ProLys: 1.975 ± 0.016	5.652ProLeu: 5.652 ± 0.031	1.462ProMet: 1.462 ± 0.014	1.763ProAsn: 1.763 ± 0.015	9.042ProPro: 9.042 ± 0.092	1.973ProGln: 1.973 ± 0.02	4.509ProArg: 4.509 ± 0.033	6.234ProSer: 6.234 ± 0.036	5.941ProThr: 5.941 ± 0.037	5.647ProVal: 5.647 ± 0.035	0.768ProTrp: 0.768 ± 0.01	1.202ProTyr: 1.202 ± 0.013	0.0ProXaa: 0.0 ± 0.0
Gln	3.87GlnAla: 3.87 ± 0.029	0.479GlnCys: 0.479 ± 0.008	1.562GlnAsp: 1.562 ± 0.015	1.564GlnGlu: 1.564 ± 0.014	1.37GlnPhe: 1.37 ± 0.014	1.854GlnGly: 1.854 ± 0.018	1.193GlnHis: 1.193 ± 0.013	1.366GlnIle: 1.366 ± 0.013	1.028GlnLys: 1.028 ± 0.014	3.849GlnLeu: 3.849 ± 0.026	0.782GlnMet: 0.782 ± 0.011	0.8GlnAsn: 0.8 ± 0.011	2.187GlnPro: 2.187 ± 0.021	3.237GlnGln: 3.237 ± 0.079	2.423GlnArg: 2.423 ± 0.019	2.254GlnSer: 2.254 ± 0.03	1.696GlnThr: 1.696 ± 0.016	2.668GlnVal: 2.668 ± 0.022	0.588GlnTrp: 0.588 ± 0.009	1.106GlnTyr: 1.106 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	8.368ArgAla: 8.368 ± 0.045	0.691ArgCys: 0.691 ± 0.009	3.92ArgAsp: 3.92 ± 0.032	2.901ArgGlu: 2.901 ± 0.024	1.943ArgPhe: 1.943 ± 0.017	3.903ArgGly: 3.903 ± 0.021	1.856ArgHis: 1.856 ± 0.015	2.528ArgIle: 2.528 ± 0.018	2.541ArgLys: 2.541 ± 0.021	5.256ArgLeu: 5.256 ± 0.024	1.382ArgMet: 1.382 ± 0.013	1.705ArgAsn: 1.705 ± 0.014	4.178ArgPro: 4.178 ± 0.03	2.191ArgGln: 2.191 ± 0.019	5.909ArgArg: 5.909 ± 0.044	4.687ArgSer: 4.687 ± 0.032	3.976ArgThr: 3.976 ± 0.022	4.573ArgVal: 4.573 ± 0.028	0.727ArgTrp: 0.727 ± 0.011	1.324ArgTyr: 1.324 ± 0.013	0.0ArgXaa: 0.0 ± 0.0
Ser	9.285SerAla: 9.285 ± 0.04	0.669SerCys: 0.669 ± 0.011	3.626SerAsp: 3.626 ± 0.024	2.4SerGlu: 2.4 ± 0.019	1.998SerPhe: 1.998 ± 0.016	4.846SerGly: 4.846 ± 0.03	1.454SerHis: 1.454 ± 0.014	2.443SerIle: 2.443 ± 0.019	2.228SerLys: 2.228 ± 0.018	6.238SerLeu: 6.238 ± 0.028	1.653SerMet: 1.653 ± 0.013	1.83SerAsn: 1.83 ± 0.017	6.142SerPro: 6.142 ± 0.039	1.938SerGln: 1.938 ± 0.027	4.476SerArg: 4.476 ± 0.031	8.057SerSer: 8.057 ± 0.07	5.957SerThr: 5.957 ± 0.044	4.842SerVal: 4.842 ± 0.03	0.818SerTrp: 0.818 ± 0.01	1.249SerTyr: 1.249 ± 0.016	0.0SerXaa: 0.0 ± 0.0
Thr	8.864ThrAla: 8.864 ± 0.044	0.758ThrCys: 0.758 ± 0.01	3.163ThrAsp: 3.163 ± 0.02	2.309ThrGlu: 2.309 ± 0.021	1.795ThrPhe: 1.795 ± 0.016	4.023ThrGly: 4.023 ± 0.024	1.53ThrHis: 1.53 ± 0.015	2.4ThrIle: 2.4 ± 0.02	2.208ThrLys: 2.208 ± 0.017	5.752ThrLeu: 5.752 ± 0.031	1.45ThrMet: 1.45 ± 0.012	1.696ThrAsn: 1.696 ± 0.016	5.375ThrPro: 5.375 ± 0.039	1.794ThrGln: 1.794 ± 0.017	3.752ThrArg: 3.752 ± 0.021	5.409ThrSer: 5.409 ± 0.037	5.94ThrThr: 5.94 ± 0.05	4.952ThrVal: 4.952 ± 0.029	0.791ThrTrp: 0.791 ± 0.009	1.219ThrTyr: 1.219 ± 0.014	0.0ThrXaa: 0.0 ± 0.0
Val	9.902ValAla: 9.902 ± 0.045	0.845ValCys: 0.845 ± 0.01	4.564ValAsp: 4.564 ± 0.026	3.884ValGlu: 3.884 ± 0.033	2.34ValPhe: 2.34 ± 0.018	4.309ValGly: 4.309 ± 0.024	2.208ValHis: 2.208 ± 0.016	2.537ValIle: 2.537 ± 0.02	2.516ValLys: 2.516 ± 0.019	7.287ValLeu: 7.287 ± 0.039	1.628ValMet: 1.628 ± 0.014	1.775ValAsn: 1.775 ± 0.015	6.257ValPro: 6.257 ± 0.035	2.864ValGln: 2.864 ± 0.018	4.61ValArg: 4.61 ± 0.024	4.52ValSer: 4.52 ± 0.026	4.567ValThr: 4.567 ± 0.025	6.535ValVal: 6.535 ± 0.038	0.882ValTrp: 0.882 ± 0.01	1.626ValTyr: 1.626 ± 0.011	0.0ValXaa: 0.0 ± 0.0
Trp	1.211TrpAla: 1.211 ± 0.013	0.197TrpCys: 0.197 ± 0.004	0.741TrpAsp: 0.741 ± 0.009	0.469TrpGlu: 0.469 ± 0.008	0.441TrpPhe: 0.441 ± 0.007	0.613TrpGly: 0.613 ± 0.008	0.37TrpHis: 0.37 ± 0.006	0.582TrpIle: 0.582 ± 0.01	0.414TrpLys: 0.414 ± 0.008	1.159TrpLeu: 1.159 ± 0.013	0.356TrpMet: 0.356 ± 0.007	0.409TrpAsn: 0.409 ± 0.008	0.698TrpPro: 0.698 ± 0.01	0.379TrpGln: 0.379 ± 0.006	0.938TrpArg: 0.938 ± 0.012	0.921TrpSer: 0.921 ± 0.011	0.999TrpThr: 0.999 ± 0.013	0.849TrpVal: 0.849 ± 0.011	0.261TrpTrp: 0.261 ± 0.005	0.32TrpTyr: 0.32 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.321TyrAla: 2.321 ± 0.018	0.327TyrCys: 0.327 ± 0.005	1.295TyrAsp: 1.295 ± 0.019	0.971TyrGlu: 0.971 ± 0.011	0.871TyrPhe: 0.871 ± 0.012	1.472TyrGly: 1.472 ± 0.016	0.63TyrHis: 0.63 ± 0.009	0.751TyrIle: 0.751 ± 0.01	0.718TyrLys: 0.718 ± 0.01	2.535TyrLeu: 2.535 ± 0.02	0.519TyrMet: 0.519 ± 0.008	0.597TyrAsn: 0.597 ± 0.009	1.197TyrPro: 1.197 ± 0.013	0.891TyrGln: 0.891 ± 0.014	1.335TyrArg: 1.335 ± 0.014	1.338TyrSer: 1.338 ± 0.013	1.141TyrThr: 1.141 ± 0.012	1.552TyrVal: 1.552 ± 0.013	0.311TyrTrp: 0.311 ± 0.007	0.699TyrTyr: 0.699 ± 0.009	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 19092 proteins (9242631 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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