Human spumaretrovirus (SFVcpz(hu)) (Human foamy virus)

Taxonomy: Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Ortervirales; Retroviridae; Spumaretrovirinae; Spumavirus; Simian foamy virus

Average proteome isoelectric point is 7.06

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|P14355|BEL3_FOAMV Protein Bel-3 OS=Human spumaretrovirus OX=11963 GN=bel3 PE=1 SV=2
MM1 pKa = 8.05DD2 pKa = 4.83SYY4 pKa = 11.55EE5 pKa = 4.37KK6 pKa = 10.49EE7 pKa = 3.88EE8 pKa = 4.54SVASTSGIQDD18 pKa = 3.7LQTLSEE24 pKa = 4.26LVGPEE29 pKa = 3.64NAGEE33 pKa = 4.39GEE35 pKa = 4.1LTIAEE40 pKa = 4.33EE41 pKa = 4.33PEE43 pKa = 4.04EE44 pKa = 4.15NPRR47 pKa = 11.84RR48 pKa = 11.84PRR50 pKa = 11.84RR51 pKa = 11.84YY52 pKa = 7.28TKK54 pKa = 10.6RR55 pKa = 11.84EE56 pKa = 4.08VKK58 pKa = 10.1CVSYY62 pKa = 10.25HH63 pKa = 6.12AYY65 pKa = 9.92KK66 pKa = 10.4EE67 pKa = 4.3IEE69 pKa = 4.59DD70 pKa = 4.02KK71 pKa = 11.09HH72 pKa = 5.66PQHH75 pKa = 7.08IKK77 pKa = 9.69LQDD80 pKa = 3.76WIPTPEE86 pKa = 4.07EE87 pKa = 3.93MSKK90 pKa = 10.53SLCKK94 pKa = 10.21RR95 pKa = 11.84LILCGLYY102 pKa = 10.29SAEE105 pKa = 4.21KK106 pKa = 9.88ASEE109 pKa = 4.02ILRR112 pKa = 11.84MPFTVSWEE120 pKa = 4.1QSDD123 pKa = 3.85TDD125 pKa = 4.07PDD127 pKa = 4.17CFIVSYY133 pKa = 9.84TCIFCDD139 pKa = 4.74AVIHH143 pKa = 6.87DD144 pKa = 4.8PMPIRR149 pKa = 11.84WDD151 pKa = 3.48PEE153 pKa = 3.45VGIWVKK159 pKa = 10.37YY160 pKa = 9.58KK161 pKa = 9.86PLRR164 pKa = 11.84GIVGSAVFIMHH175 pKa = 6.42KK176 pKa = 9.81HH177 pKa = 4.71QRR179 pKa = 11.84NCSLVKK185 pKa = 10.36PSTSCSEE192 pKa = 4.2GPKK195 pKa = 9.62PRR197 pKa = 11.84PRR199 pKa = 11.84HH200 pKa = 5.92DD201 pKa = 3.25PVLRR205 pKa = 11.84CDD207 pKa = 3.51MFEE210 pKa = 3.94KK211 pKa = 10.14HH212 pKa = 6.28HH213 pKa = 6.71KK214 pKa = 9.43PRR216 pKa = 11.84QKK218 pKa = 9.95RR219 pKa = 11.84PRR221 pKa = 11.84RR222 pKa = 11.84RR223 pKa = 11.84SIDD226 pKa = 3.51NEE228 pKa = 4.28SCASSSDD235 pKa = 3.23TMANEE240 pKa = 4.24PGSLCTNPLWNPGPLLSGLLEE261 pKa = 4.33EE262 pKa = 5.57SSNLPNLEE270 pKa = 3.81VHH272 pKa = 5.92MSGGPFWEE280 pKa = 4.27EE281 pKa = 4.24VYY283 pKa = 10.96GDD285 pKa = 4.66SILGPPSGSGEE296 pKa = 4.05HH297 pKa = 6.54SVLL300 pKa = 4.05

Molecular weight: 33.89 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|P14350|POL_FOAMV Pro-Pol polyprotein OS=Human spumaretrovirus OX=11963 GN=pol PE=1 SV=2
MM1 pKa = 7.65ASGSNVEE8 pKa = 4.34EE9 pKa = 4.45YY10 pKa = 10.68EE11 pKa = 4.22LDD13 pKa = 3.64VEE15 pKa = 4.3ALVVILRR22 pKa = 11.84DD23 pKa = 3.56RR24 pKa = 11.84NIPRR28 pKa = 11.84NPLHH32 pKa = 6.68GEE34 pKa = 4.17VIGLRR39 pKa = 11.84LTEE42 pKa = 4.28GWWGQIEE49 pKa = 4.43RR50 pKa = 11.84FQMVRR55 pKa = 11.84LILQDD60 pKa = 4.26DD61 pKa = 4.26DD62 pKa = 5.07NEE64 pKa = 4.13PLQRR68 pKa = 11.84PRR70 pKa = 11.84YY71 pKa = 8.81EE72 pKa = 4.23VIQRR76 pKa = 11.84AVNPHH81 pKa = 4.39TMFMISGPLAEE92 pKa = 5.03LQLAFQDD99 pKa = 3.63LDD101 pKa = 3.93LPEE104 pKa = 5.19GPLRR108 pKa = 11.84FGPLANGHH116 pKa = 5.52YY117 pKa = 10.12VQGDD121 pKa = 4.15PYY123 pKa = 9.92SSSYY127 pKa = 10.97RR128 pKa = 11.84PVTMAEE134 pKa = 4.14TAQMTRR140 pKa = 11.84DD141 pKa = 3.55EE142 pKa = 5.44LEE144 pKa = 4.68DD145 pKa = 3.51VLNTQSEE152 pKa = 4.51IEE154 pKa = 3.87IQMINLLEE162 pKa = 4.42LYY164 pKa = 9.83EE165 pKa = 4.24VEE167 pKa = 3.99TRR169 pKa = 11.84ALRR172 pKa = 11.84RR173 pKa = 11.84QLAEE177 pKa = 4.01RR178 pKa = 11.84SSTGQGGISPGAPRR192 pKa = 11.84SRR194 pKa = 11.84PPVSSFSGLPSLPSIPGIHH213 pKa = 6.77PRR215 pKa = 11.84APSPPRR221 pKa = 11.84ATSTPGNIPWSLGDD235 pKa = 4.42DD236 pKa = 4.06SPPSSSFPGPSQPRR250 pKa = 11.84VSFHH254 pKa = 6.89PGNPFVEE261 pKa = 4.81EE262 pKa = 3.83EE263 pKa = 4.09GHH265 pKa = 6.18RR266 pKa = 11.84PRR268 pKa = 11.84SQSRR272 pKa = 11.84EE273 pKa = 3.56RR274 pKa = 11.84RR275 pKa = 11.84RR276 pKa = 11.84EE277 pKa = 3.73ILPAPVPSAPPMIQYY292 pKa = 10.08IPVPPPPPIGTVIPIQHH309 pKa = 6.14IRR311 pKa = 11.84SVTGEE316 pKa = 3.86PPRR319 pKa = 11.84NPRR322 pKa = 11.84EE323 pKa = 3.71IPIWLGRR330 pKa = 11.84NAPAIDD336 pKa = 3.66GVFPVTTPDD345 pKa = 3.21LRR347 pKa = 11.84CRR349 pKa = 11.84IINAILGGNIGLSLTPGDD367 pKa = 4.24CLTWDD372 pKa = 3.69SAVATLFIRR381 pKa = 11.84THH383 pKa = 5.47GTFPMHH389 pKa = 6.36QLGNVIKK396 pKa = 10.81GIVDD400 pKa = 3.44QEE402 pKa = 4.65GVATAYY408 pKa = 9.37TLGMMLSGQNYY419 pKa = 8.48QLVSGIIRR427 pKa = 11.84GYY429 pKa = 10.92LPGQAVVTALQQRR442 pKa = 11.84LDD444 pKa = 3.77QEE446 pKa = 4.12IDD448 pKa = 3.17NQTRR452 pKa = 11.84AEE454 pKa = 4.14TFIQHH459 pKa = 6.48LNAVYY464 pKa = 10.31EE465 pKa = 4.1ILGLNARR472 pKa = 11.84GQSIRR477 pKa = 11.84ASVTPQPRR485 pKa = 11.84PSRR488 pKa = 11.84GRR490 pKa = 11.84GRR492 pKa = 11.84GQNTSRR498 pKa = 11.84PSQGPANSGRR508 pKa = 11.84GRR510 pKa = 11.84QRR512 pKa = 11.84PASGQSNRR520 pKa = 11.84GSSTQNQNQDD530 pKa = 3.09NLNQGGYY537 pKa = 7.7NLRR540 pKa = 11.84PRR542 pKa = 11.84TYY544 pKa = 9.41QPQRR548 pKa = 11.84YY549 pKa = 8.66GGGRR553 pKa = 11.84GRR555 pKa = 11.84RR556 pKa = 11.84WNDD559 pKa = 2.73NTNNQEE565 pKa = 4.53SRR567 pKa = 11.84PSDD570 pKa = 3.16QGSQTPRR577 pKa = 11.84PNQAGSGVRR586 pKa = 11.84GNQSQTPRR594 pKa = 11.84PAAGRR599 pKa = 11.84GGRR602 pKa = 11.84GNHH605 pKa = 5.78NRR607 pKa = 11.84NQRR610 pKa = 11.84SSGAGDD616 pKa = 3.14SRR618 pKa = 11.84AVNTVTQSATSSTDD632 pKa = 3.12EE633 pKa = 4.12SSSAVTAASGGDD645 pKa = 3.34QRR647 pKa = 11.84DD648 pKa = 3.15

Molecular weight: 70.59 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

6

1

7

4078

160

1143

582.6

66.09

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.321 ± 0.24

1.717 ± 0.473

4.512 ± 0.33

6.106 ± 0.516

2.673 ± 0.219

6.229 ± 0.963

2.55 ± 0.192

6.032 ± 0.559

5.812 ± 1.11

8.95 ± 0.896

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.158 ± 0.294

4.586 ± 0.441

7.258 ± 0.818

5.763 ± 0.415

5.468 ± 0.914

6.842 ± 0.62

6.032 ± 0.361

5.836 ± 0.397

2.035 ± 0.235

4.12 ± 0.537
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski