Amino acid dipepetide frequency for Tacaiuma orthobunyavirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.279AlaAla: 1.279 ± 0.714
0.767AlaCys: 0.767 ± 0.138
3.07AlaAsp: 3.07 ± 1.059
1.791AlaGlu: 1.791 ± 1.005
1.791AlaPhe: 1.791 ± 0.447
1.023AlaGly: 1.023 ± 1.79
1.023AlaHis: 1.023 ± 0.584
3.326AlaIle: 3.326 ± 0.767
2.047AlaLys: 2.047 ± 1.608
4.861AlaLeu: 4.861 ± 1.416
1.279AlaMet: 1.279 ± 0.202
4.349AlaAsn: 4.349 ± 0.466
0.512AlaPro: 0.512 ± 0.308
1.279AlaGln: 1.279 ± 0.416
2.302AlaArg: 2.302 ± 0.499
1.023AlaSer: 1.023 ± 0.23
2.814AlaThr: 2.814 ± 0.778
2.558AlaVal: 2.558 ± 0.311
0.256AlaTrp: 0.256 ± 0.154
1.535AlaTyr: 1.535 ± 0.276
0.0AlaXaa: 0.0 ± 0.0
Cys
1.023CysAla: 1.023 ± 0.269
0.512CysCys: 0.512 ± 0.115
1.023CysAsp: 1.023 ± 0.23
1.791CysGlu: 1.791 ± 0.9
1.791CysPhe: 1.791 ± 0.553
2.558CysGly: 2.558 ± 1.966
0.256CysHis: 0.256 ± 0.234
2.558CysIle: 2.558 ± 0.574
3.326CysLys: 3.326 ± 2.667
2.302CysLeu: 2.302 ± 0.404
0.256CysMet: 0.256 ± 0.154
1.279CysAsn: 1.279 ± 0.442
1.791CysPro: 1.791 ± 0.447
0.512CysGln: 0.512 ± 0.308
1.535CysArg: 1.535 ± 1.032
1.535CysSer: 1.535 ± 0.575
1.791CysThr: 1.791 ± 1.265
1.279CysVal: 1.279 ± 0.799
0.512CysTrp: 0.512 ± 0.115
1.535CysTyr: 1.535 ± 0.669
0.0CysXaa: 0.0 ± 0.0
Asp
1.535AspAla: 1.535 ± 0.344
1.791AspCys: 1.791 ± 0.553
3.581AspAsp: 3.581 ± 0.369
2.558AspGlu: 2.558 ± 0.532
5.884AspPhe: 5.884 ± 1.431
1.023AspGly: 1.023 ± 0.566
0.512AspHis: 0.512 ± 0.308
6.14AspIle: 6.14 ± 0.643
3.07AspLys: 3.07 ± 0.552
4.861AspLeu: 4.861 ± 1.449
2.047AspMet: 2.047 ± 0.459
2.814AspAsn: 2.814 ± 0.514
3.326AspPro: 3.326 ± 0.639
2.047AspGln: 2.047 ± 0.776
2.047AspArg: 2.047 ± 0.459
2.814AspSer: 2.814 ± 0.737
3.07AspThr: 3.07 ± 0.552
3.326AspVal: 3.326 ± 0.951
0.512AspTrp: 0.512 ± 0.115
3.581AspTyr: 3.581 ± 0.593
0.0AspXaa: 0.0 ± 0.0
Glu
1.535GluAla: 1.535 ± 0.344
2.302GluCys: 2.302 ± 0.404
3.07GluAsp: 3.07 ± 0.552
5.116GluGlu: 5.116 ± 0.91
6.14GluPhe: 6.14 ± 1.047
1.535GluGly: 1.535 ± 0.566
0.767GluHis: 0.767 ± 0.335
5.372GluIle: 5.372 ± 1.738
4.605GluLys: 4.605 ± 0.565
6.651GluLeu: 6.651 ± 1.902
1.535GluMet: 1.535 ± 0.566
1.791GluAsn: 1.791 ± 0.718
1.791GluPro: 1.791 ± 1.077
2.558GluGln: 2.558 ± 1.177
4.093GluArg: 4.093 ± 0.7
5.628GluSer: 5.628 ± 1.027
3.581GluThr: 3.581 ± 0.593
2.814GluVal: 2.814 ± 1.288
0.512GluTrp: 0.512 ± 0.577
2.558GluTyr: 2.558 ± 0.301
0.0GluXaa: 0.0 ± 0.0
Phe
1.279PheAla: 1.279 ± 1.085
1.535PheCys: 1.535 ± 1.063
3.07PheAsp: 3.07 ± 0.505
2.302PheGlu: 2.302 ± 0.683
2.558PhePhe: 2.558 ± 0.955
2.558PheGly: 2.558 ± 0.301
0.767PheHis: 0.767 ± 0.702
5.628PheIle: 5.628 ± 0.252
4.093PheLys: 4.093 ± 0.443
5.372PheLeu: 5.372 ± 2.397
2.302PheMet: 2.302 ± 0.427
3.581PheAsn: 3.581 ± 1.098
1.023PhePro: 1.023 ± 0.23
1.279PheGln: 1.279 ± 0.442
3.07PheArg: 3.07 ± 0.806
4.605PheSer: 4.605 ± 1.033
2.302PheThr: 2.302 ± 0.683
3.07PheVal: 3.07 ± 1.247
0.512PheTrp: 0.512 ± 0.308
2.302PheTyr: 2.302 ± 0.499
0.0PheXaa: 0.0 ± 0.0
Gly
1.279GlyAla: 1.279 ± 0.714
2.558GlyCys: 2.558 ± 0.574
2.814GlyAsp: 2.814 ± 0.737
3.07GlyGlu: 3.07 ± 0.322
2.047GlyPhe: 2.047 ± 0.589
0.767GlyGly: 0.767 ± 0.335
0.767GlyHis: 0.767 ± 0.462
2.558GlyIle: 2.558 ± 0.955
1.535GlyLys: 1.535 ± 0.403
4.349GlyLeu: 4.349 ± 1.431
0.767GlyMet: 0.767 ± 0.312
2.302GlyAsn: 2.302 ± 0.445
1.535GlyPro: 1.535 ± 0.276
0.767GlyGln: 0.767 ± 0.335
2.047GlyArg: 2.047 ± 0.718
2.814GlySer: 2.814 ± 0.87
2.302GlyThr: 2.302 ± 1.139
1.279GlyVal: 1.279 ± 0.484
0.767GlyTrp: 0.767 ± 0.335
1.535GlyTyr: 1.535 ± 0.276
0.0GlyXaa: 0.0 ± 0.0
His
1.023HisAla: 1.023 ± 0.566
0.256HisCys: 0.256 ± 0.234
0.767HisAsp: 0.767 ± 0.138
0.512HisGlu: 0.512 ± 0.115
1.023HisPhe: 1.023 ± 0.269
1.023HisGly: 1.023 ± 0.269
1.023HisHis: 1.023 ± 0.269
1.535HisIle: 1.535 ± 1.032
1.791HisLys: 1.791 ± 0.718
1.535HisLeu: 1.535 ± 0.276
0.767HisMet: 0.767 ± 0.335
1.791HisAsn: 1.791 ± 0.612
1.535HisPro: 1.535 ± 0.344
0.256HisGln: 0.256 ± 0.234
1.023HisArg: 1.023 ± 0.858
2.302HisSer: 2.302 ± 0.839
1.279HisThr: 1.279 ± 0.202
0.512HisVal: 0.512 ± 0.577
0.256HisTrp: 0.256 ± 0.154
1.279HisTyr: 1.279 ± 0.478
0.0HisXaa: 0.0 ± 0.0
Ile
4.605IleAla: 4.605 ± 0.531
2.047IleCys: 2.047 ± 1.499
4.605IleAsp: 4.605 ± 0.247
7.163IleGlu: 7.163 ± 0.515
3.07IlePhe: 3.07 ± 0.873
3.326IleGly: 3.326 ± 0.276
2.302IleHis: 2.302 ± 0.414
4.861IleIle: 4.861 ± 0.752
6.651IleLys: 6.651 ± 0.777
8.442IleLeu: 8.442 ± 0.738
2.302IleMet: 2.302 ± 1.024
4.093IleAsn: 4.093 ± 0.064
1.791IlePro: 1.791 ± 0.737
3.07IleGln: 3.07 ± 0.505
2.047IleArg: 2.047 ± 0.718
7.93IleSer: 7.93 ± 1.057
6.651IleThr: 6.651 ± 1.418
5.884IleVal: 5.884 ± 0.998
0.767IleTrp: 0.767 ± 0.462
3.581IleTyr: 3.581 ± 1.736
0.0IleXaa: 0.0 ± 0.0
Lys
2.814LysAla: 2.814 ± 1.486
2.302LysCys: 2.302 ± 1.733
4.861LysAsp: 4.861 ± 0.395
4.093LysGlu: 4.093 ± 1.397
3.837LysPhe: 3.837 ± 1.451
3.326LysGly: 3.326 ± 0.639
1.791LysHis: 1.791 ± 0.553
6.395LysIle: 6.395 ± 0.437
3.837LysLys: 3.837 ± 0.78
9.977LysLeu: 9.977 ± 1.147
2.558LysMet: 2.558 ± 0.574
4.605LysAsn: 4.605 ± 0.808
2.302LysPro: 2.302 ± 0.777
2.302LysGln: 2.302 ± 1.004
3.581LysArg: 3.581 ± 0.78
6.395LysSer: 6.395 ± 1.324
5.372LysThr: 5.372 ± 0.217
3.326LysVal: 3.326 ± 0.891
0.256LysTrp: 0.256 ± 0.154
2.047LysTyr: 2.047 ± 0.341
0.0LysXaa: 0.0 ± 0.0
Leu
3.581LeuAla: 3.581 ± 2.664
1.279LeuCys: 1.279 ± 0.799
5.372LeuAsp: 5.372 ± 1.077
6.14LeuGlu: 6.14 ± 0.99
6.14LeuPhe: 6.14 ± 0.978
2.047LeuGly: 2.047 ± 0.415
2.047LeuHis: 2.047 ± 0.415
6.395LeuIle: 6.395 ± 0.63
7.675LeuLys: 7.675 ± 0.752
8.954LeuLeu: 8.954 ± 0.773
1.023LeuMet: 1.023 ± 1.131
6.14LeuAsn: 6.14 ± 0.835
4.349LeuPro: 4.349 ± 0.696
2.558LeuGln: 2.558 ± 0.883
5.116LeuArg: 5.116 ± 0.91
7.93LeuSer: 7.93 ± 2.126
6.907LeuThr: 6.907 ± 1.739
3.837LeuVal: 3.837 ± 0.592
0.512LeuTrp: 0.512 ± 0.308
2.814LeuTyr: 2.814 ± 0.458
0.0LeuXaa: 0.0 ± 0.0
Met
0.256MetAla: 0.256 ± 0.154
0.512MetCys: 0.512 ± 0.115
1.279MetAsp: 1.279 ± 0.202
4.349MetGlu: 4.349 ± 1.219
0.512MetPhe: 0.512 ± 0.468
0.767MetGly: 0.767 ± 0.335
0.256MetHis: 0.256 ± 0.154
3.581MetIle: 3.581 ± 0.803
3.07MetLys: 3.07 ± 1.453
2.558MetLeu: 2.558 ± 1.177
1.023MetMet: 1.023 ± 0.269
1.279MetAsn: 1.279 ± 0.416
1.023MetPro: 1.023 ± 0.23
0.767MetGln: 0.767 ± 0.462
0.767MetArg: 0.767 ± 0.462
1.791MetSer: 1.791 ± 0.612
3.07MetThr: 3.07 ± 0.505
0.512MetVal: 0.512 ± 0.468
0.0MetTrp: 0.0 ± 0.0
1.535MetTyr: 1.535 ± 0.669
0.0MetXaa: 0.0 ± 0.0
Asn
2.558AsnAla: 2.558 ± 1.451
1.279AsnCys: 1.279 ± 0.799
4.093AsnAsp: 4.093 ± 0.652
1.535AsnGlu: 1.535 ± 0.566
2.047AsnPhe: 2.047 ± 0.537
1.791AsnGly: 1.791 ± 1.083
1.791AsnHis: 1.791 ± 0.398
3.837AsnIle: 3.837 ± 0.547
4.093AsnLys: 4.093 ± 1.075
2.814AsnLeu: 2.814 ± 0.458
2.047AsnMet: 2.047 ± 0.415
3.07AsnAsn: 3.07 ± 1.133
2.558AsnPro: 2.558 ± 0.532
1.791AsnGln: 1.791 ± 0.398
3.581AsnArg: 3.581 ± 0.78
4.349AsnSer: 4.349 ± 0.607
5.372AsnThr: 5.372 ± 0.708
2.558AsnVal: 2.558 ± 0.574
0.512AsnTrp: 0.512 ± 0.115
3.326AsnTyr: 3.326 ± 0.625
0.0AsnXaa: 0.0 ± 0.0
Pro
1.279ProAla: 1.279 ± 0.769
1.023ProCys: 1.023 ± 0.935
3.581ProAsp: 3.581 ± 0.596
3.581ProGlu: 3.581 ± 0.758
1.535ProPhe: 1.535 ± 0.344
2.558ProGly: 2.558 ± 1.642
0.512ProHis: 0.512 ± 0.615
3.326ProIle: 3.326 ± 0.524
2.047ProLys: 2.047 ± 1.292
3.07ProLeu: 3.07 ± 1.453
1.279ProMet: 1.279 ± 0.416
1.279ProAsn: 1.279 ± 0.416
1.535ProPro: 1.535 ± 0.276
1.535ProGln: 1.535 ± 0.344
1.279ProArg: 1.279 ± 0.478
1.279ProSer: 1.279 ± 0.416
2.814ProThr: 2.814 ± 0.514
1.791ProVal: 1.791 ± 0.398
0.256ProTrp: 0.256 ± 0.154
1.791ProTyr: 1.791 ± 0.298
0.0ProXaa: 0.0 ± 0.0
Gln
2.047GlnAla: 2.047 ± 0.776
1.023GlnCys: 1.023 ± 0.935
2.814GlnAsp: 2.814 ± 0.666
1.023GlnGlu: 1.023 ± 0.269
0.767GlnPhe: 0.767 ± 0.335
1.279GlnGly: 1.279 ± 0.202
0.512GlnHis: 0.512 ± 0.308
4.093GlnIle: 4.093 ± 0.821
1.791GlnLys: 1.791 ± 1.077
1.279GlnLeu: 1.279 ± 0.202
0.512GlnMet: 0.512 ± 0.115
2.302GlnAsn: 2.302 ± 0.499
0.0GlnPro: 0.0 ± 0.0
1.023GlnGln: 1.023 ± 0.484
3.326GlnArg: 3.326 ± 1.013
2.814GlnSer: 2.814 ± 0.859
2.302GlnThr: 2.302 ± 0.777
1.791GlnVal: 1.791 ± 0.398
0.256GlnTrp: 0.256 ± 0.154
0.512GlnTyr: 0.512 ± 0.115
0.0GlnXaa: 0.0 ± 0.0
Arg
1.023ArgAla: 1.023 ± 0.484
2.047ArgCys: 2.047 ± 0.326
1.791ArgAsp: 1.791 ± 0.553
4.093ArgGlu: 4.093 ± 1.831
2.047ArgPhe: 2.047 ± 0.871
1.279ArgGly: 1.279 ± 0.478
1.023ArgHis: 1.023 ± 0.269
4.349ArgIle: 4.349 ± 0.905
4.093ArgLys: 4.093 ± 0.443
3.326ArgLeu: 3.326 ± 0.639
1.023ArgMet: 1.023 ± 0.197
3.07ArgAsn: 3.07 ± 0.806
1.791ArgPro: 1.791 ± 0.737
1.279ArgGln: 1.279 ± 0.714
0.512ArgArg: 0.512 ± 0.308
3.326ArgSer: 3.326 ± 0.951
2.302ArgThr: 2.302 ± 1.004
1.791ArgVal: 1.791 ± 0.447
0.512ArgTrp: 0.512 ± 0.115
2.558ArgTyr: 2.558 ± 0.301
0.0ArgXaa: 0.0 ± 0.0
Ser
4.349SerAla: 4.349 ± 0.905
1.023SerCys: 1.023 ± 0.23
2.558SerAsp: 2.558 ± 0.61
5.628SerGlu: 5.628 ± 0.773
2.047SerPhe: 2.047 ± 1.169
3.326SerGly: 3.326 ± 0.891
1.791SerHis: 1.791 ± 0.398
7.419SerIle: 7.419 ± 1.277
9.465SerLys: 9.465 ± 2.14
6.14SerLeu: 6.14 ± 1.17
2.302SerMet: 2.302 ± 1.024
3.07SerAsn: 3.07 ± 0.552
2.814SerPro: 2.814 ± 0.206
1.791SerGln: 1.791 ± 0.398
3.837SerArg: 3.837 ± 0.171
5.628SerSer: 5.628 ± 1.078
6.395SerThr: 6.395 ± 1.426
4.605SerVal: 4.605 ± 0.997
1.023SerTrp: 1.023 ± 0.484
4.093SerTyr: 4.093 ± 0.652
0.0SerXaa: 0.0 ± 0.0
Thr
2.558ThrAla: 2.558 ± 1.177
3.07ThrCys: 3.07 ± 1.339
3.581ThrAsp: 3.581 ± 1.106
3.326ThrGlu: 3.326 ± 0.524
4.349ThrPhe: 4.349 ± 0.93
3.837ThrGly: 3.837 ± 1.673
1.279ThrHis: 1.279 ± 1.139
4.861ThrIle: 4.861 ± 0.783
5.372ThrLys: 5.372 ± 1.078
5.116ThrLeu: 5.116 ± 1.605
2.047ThrMet: 2.047 ± 0.326
2.302ThrAsn: 2.302 ± 0.445
2.558ThrPro: 2.558 ± 0.967
2.302ThrGln: 2.302 ± 0.499
1.279ThrArg: 1.279 ± 0.202
7.419ThrSer: 7.419 ± 1.277
2.558ThrThr: 2.558 ± 1.234
3.326ThrVal: 3.326 ± 0.668
0.767ThrTrp: 0.767 ± 0.702
4.605ThrTyr: 4.605 ± 0.827
0.0ThrXaa: 0.0 ± 0.0
Val
3.326ValAla: 3.326 ± 0.639
2.814ValCys: 2.814 ± 1.11
1.791ValAsp: 1.791 ± 0.398
2.814ValGlu: 2.814 ± 1.031
1.023ValPhe: 1.023 ± 0.484
2.558ValGly: 2.558 ± 0.574
1.535ValHis: 1.535 ± 0.344
3.326ValIle: 3.326 ± 0.625
4.349ValLys: 4.349 ± 1.033
4.093ValLeu: 4.093 ± 0.064
1.279ValMet: 1.279 ± 0.416
2.047ValAsn: 2.047 ± 0.718
3.581ValPro: 3.581 ± 0.405
1.535ValGln: 1.535 ± 0.403
0.512ValArg: 0.512 ± 0.115
5.628ValSer: 5.628 ± 1.841
1.791ValThr: 1.791 ± 0.298
2.558ValVal: 2.558 ± 0.574
0.512ValTrp: 0.512 ± 0.468
3.07ValTyr: 3.07 ± 0.689
0.0ValXaa: 0.0 ± 0.0
Trp
0.256TrpAla: 0.256 ± 0.603
0.0TrpCys: 0.0 ± 0.0
0.512TrpAsp: 0.512 ± 0.115
0.767TrpGlu: 0.767 ± 0.138
0.767TrpPhe: 0.767 ± 0.138
0.512TrpGly: 0.512 ± 0.468
0.256TrpHis: 0.256 ± 0.234
0.512TrpIle: 0.512 ± 0.308
0.512TrpLys: 0.512 ± 0.115
1.023TrpLeu: 1.023 ± 0.23
1.023TrpMet: 1.023 ± 0.484
1.023TrpAsn: 1.023 ± 0.269
0.0TrpPro: 0.0 ± 0.0
0.256TrpGln: 0.256 ± 0.234
0.0TrpArg: 0.0 ± 0.0
1.023TrpSer: 1.023 ± 0.269
0.512TrpThr: 0.512 ± 0.308
0.256TrpVal: 0.256 ± 0.154
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.279TyrAla: 1.279 ± 0.478
1.023TyrCys: 1.023 ± 0.566
2.302TyrAsp: 2.302 ± 0.445
2.302TyrGlu: 2.302 ± 0.414
3.837TyrPhe: 3.837 ± 0.605
1.023TyrGly: 1.023 ± 0.484
1.279TyrHis: 1.279 ± 0.202
5.116TyrIle: 5.116 ± 0.998
2.558TyrLys: 2.558 ± 0.403
4.093TyrLeu: 4.093 ± 0.821
1.279TyrMet: 1.279 ± 0.202
2.814TyrAsn: 2.814 ± 0.737
1.535TyrPro: 1.535 ± 1.194
2.558TyrGln: 2.558 ± 0.532
1.279TyrArg: 1.279 ± 0.202
3.07TyrSer: 3.07 ± 1.133
3.326TyrThr: 3.326 ± 0.951
3.07TyrVal: 3.07 ± 1.339
0.512TyrTrp: 0.512 ± 0.115
1.535TyrTyr: 1.535 ± 0.344
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3910 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski