Amino acid dipepetide frequency for Lentinus tigrinus ALCF2SS1-6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.838AlaAla: 9.838 ± 0.061	1.24AlaCys: 1.24 ± 0.018	4.548AlaAsp: 4.548 ± 0.027	5.077AlaGlu: 5.077 ± 0.038	3.38AlaPhe: 3.38 ± 0.024	5.718AlaGly: 5.718 ± 0.033	2.4AlaHis: 2.4 ± 0.019	4.027AlaIle: 4.027 ± 0.027	3.688AlaLys: 3.688 ± 0.031	8.843AlaLeu: 8.843 ± 0.043	2.019AlaMet: 2.019 ± 0.017	2.72AlaAsn: 2.72 ± 0.023	6.024AlaPro: 6.024 ± 0.048	3.603AlaGln: 3.603 ± 0.032	6.019AlaArg: 6.019 ± 0.038	8.116AlaSer: 8.116 ± 0.044	5.444AlaThr: 5.444 ± 0.037	5.874AlaVal: 5.874 ± 0.037	1.263AlaTrp: 1.263 ± 0.015	2.305AlaTyr: 2.305 ± 0.022	0.0AlaXaa: 0.0 ± 0.0
Cys	1.223CysAla: 1.223 ± 0.019	0.308CysCys: 0.308 ± 0.008	0.694CysAsp: 0.694 ± 0.012	0.639CysGlu: 0.639 ± 0.011	0.512CysPhe: 0.512 ± 0.009	0.996CysGly: 0.996 ± 0.014	0.372CysHis: 0.372 ± 0.009	0.698CysIle: 0.698 ± 0.011	0.51CysLys: 0.51 ± 0.01	1.279CysLeu: 1.279 ± 0.016	0.315CysMet: 0.315 ± 0.007	0.403CysAsn: 0.403 ± 0.009	0.876CysPro: 0.876 ± 0.013	0.435CysGln: 0.435 ± 0.009	0.914CysArg: 0.914 ± 0.012	1.07CysSer: 1.07 ± 0.014	0.829CysThr: 0.829 ± 0.012	0.901CysVal: 0.901 ± 0.013	0.21CysTrp: 0.21 ± 0.005	0.368CysTyr: 0.368 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	5.325AspAla: 5.325 ± 0.03	0.657AspCys: 0.657 ± 0.011	4.261AspAsp: 4.261 ± 0.034	4.297AspGlu: 4.297 ± 0.037	1.978AspPhe: 1.978 ± 0.019	4.038AspGly: 4.038 ± 0.03	1.222AspHis: 1.222 ± 0.014	2.86AspIle: 2.86 ± 0.022	2.018AspLys: 2.018 ± 0.022	4.824AspLeu: 4.824 ± 0.033	1.253AspMet: 1.253 ± 0.015	1.496AspAsn: 1.496 ± 0.019	3.659AspPro: 3.659 ± 0.026	1.491AspGln: 1.491 ± 0.017	3.005AspArg: 3.005 ± 0.024	3.9AspSer: 3.9 ± 0.027	2.952AspThr: 2.952 ± 0.022	4.277AspVal: 4.277 ± 0.034	0.913AspTrp: 0.913 ± 0.013	1.465AspTyr: 1.465 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.053GluAla: 5.053 ± 0.037	0.665GluCys: 0.665 ± 0.01	4.209GluAsp: 4.209 ± 0.032	5.175GluGlu: 5.175 ± 0.052	1.794GluPhe: 1.794 ± 0.017	3.608GluGly: 3.608 ± 0.028	1.548GluHis: 1.548 ± 0.015	2.453GluIle: 2.453 ± 0.02	2.858GluLys: 2.858 ± 0.027	5.39GluLeu: 5.39 ± 0.038	1.249GluMet: 1.249 ± 0.015	1.655GluAsn: 1.655 ± 0.018	2.878GluPro: 2.878 ± 0.028	2.198GluGln: 2.198 ± 0.022	4.155GluArg: 4.155 ± 0.031	3.715GluSer: 3.715 ± 0.028	2.926GluThr: 2.926 ± 0.021	3.75GluVal: 3.75 ± 0.029	0.895GluTrp: 0.895 ± 0.013	1.536GluTyr: 1.536 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	3.307PheAla: 3.307 ± 0.026	0.552PheCys: 0.552 ± 0.01	2.2PheAsp: 2.2 ± 0.021	1.861PheGlu: 1.861 ± 0.019	1.504PhePhe: 1.504 ± 0.015	2.621PheGly: 2.621 ± 0.03	0.885PheHis: 0.885 ± 0.012	1.645PheIle: 1.645 ± 0.021	1.343PheLys: 1.343 ± 0.016	3.443PheLeu: 3.443 ± 0.025	0.761PheMet: 0.761 ± 0.011	1.204PheAsn: 1.204 ± 0.014	2.185PhePro: 2.185 ± 0.019	1.138PheGln: 1.138 ± 0.012	2.034PheArg: 2.034 ± 0.019	2.957PheSer: 2.957 ± 0.02	2.156PheThr: 2.156 ± 0.017	2.623PheVal: 2.623 ± 0.022	0.584PheTrp: 0.584 ± 0.011	0.996PheTyr: 0.996 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	5.401GlyAla: 5.401 ± 0.035	0.917GlyCys: 0.917 ± 0.014	3.474GlyAsp: 3.474 ± 0.026	3.44GlyGlu: 3.44 ± 0.025	2.446GlyPhe: 2.446 ± 0.025	5.303GlyGly: 5.303 ± 0.05	1.717GlyHis: 1.717 ± 0.018	2.981GlyIle: 2.981 ± 0.028	3.069GlyLys: 3.069 ± 0.025	5.547GlyLeu: 5.547 ± 0.032	1.541GlyMet: 1.541 ± 0.02	2.015GlyAsn: 2.015 ± 0.02	3.635GlyPro: 3.635 ± 0.028	2.285GlyGln: 2.285 ± 0.019	4.291GlyArg: 4.291 ± 0.033	5.593GlySer: 5.593 ± 0.037	4.101GlyThr: 4.101 ± 0.029	4.342GlyVal: 4.342 ± 0.026	1.123GlyTrp: 1.123 ± 0.016	1.841GlyTyr: 1.841 ± 0.02	0.0GlyXaa: 0.0 ± 0.0
His	2.453HisAla: 2.453 ± 0.021	0.387HisCys: 0.387 ± 0.009	1.406HisAsp: 1.406 ± 0.016	1.31HisGlu: 1.31 ± 0.016	0.949HisPhe: 0.949 ± 0.012	1.773HisGly: 1.773 ± 0.018	0.883HisHis: 0.883 ± 0.015	1.288HisIle: 1.288 ± 0.015	0.867HisLys: 0.867 ± 0.012	2.581HisLeu: 2.581 ± 0.021	0.531HisMet: 0.531 ± 0.008	0.77HisAsn: 0.77 ± 0.012	2.131HisPro: 2.131 ± 0.02	0.843HisGln: 0.843 ± 0.012	1.767HisArg: 1.767 ± 0.017	2.071HisSer: 2.071 ± 0.023	1.563HisThr: 1.563 ± 0.015	1.797HisVal: 1.797 ± 0.017	0.366HisTrp: 0.366 ± 0.008	0.714HisTyr: 0.714 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.076IleAla: 4.076 ± 0.024	0.691IleCys: 0.691 ± 0.011	2.55IleAsp: 2.55 ± 0.021	2.37IleGlu: 2.37 ± 0.019	1.678IlePhe: 1.678 ± 0.017	2.714IleGly: 2.714 ± 0.021	1.163IleHis: 1.163 ± 0.013	2.095IleIle: 2.095 ± 0.02	1.672IleLys: 1.672 ± 0.017	4.249IleLeu: 4.249 ± 0.031	0.914IleMet: 0.914 ± 0.013	1.321IleAsn: 1.321 ± 0.014	3.238IlePro: 3.238 ± 0.025	1.528IleGln: 1.528 ± 0.016	2.734IleArg: 2.734 ± 0.023	3.394IleSer: 3.394 ± 0.026	2.567IleThr: 2.567 ± 0.022	3.204IleVal: 3.204 ± 0.023	0.663IleTrp: 0.663 ± 0.012	1.229IleTyr: 1.229 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	3.896LysAla: 3.896 ± 0.036	0.44LysCys: 0.44 ± 0.01	2.326LysAsp: 2.326 ± 0.024	2.746LysGlu: 2.746 ± 0.024	1.248LysPhe: 1.248 ± 0.014	2.556LysGly: 2.556 ± 0.024	1.062LysHis: 1.062 ± 0.014	1.69LysIle: 1.69 ± 0.017	2.579LysLys: 2.579 ± 0.033	3.64LysLeu: 3.64 ± 0.027	0.818LysMet: 0.818 ± 0.012	1.267LysAsn: 1.267 ± 0.013	2.436LysPro: 2.436 ± 0.022	1.461LysGln: 1.461 ± 0.019	3.153LysArg: 3.153 ± 0.028	2.727LysSer: 2.727 ± 0.023	2.335LysThr: 2.335 ± 0.019	2.53LysVal: 2.53 ± 0.025	0.624LysTrp: 0.624 ± 0.01	1.16LysTyr: 1.16 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	8.455LeuAla: 8.455 ± 0.036	1.352LeuCys: 1.352 ± 0.017	5.096LeuAsp: 5.096 ± 0.032	5.283LeuGlu: 5.283 ± 0.038	3.36LeuPhe: 3.36 ± 0.026	5.566LeuGly: 5.566 ± 0.036	2.656LeuHis: 2.656 ± 0.023	3.572LeuIle: 3.572 ± 0.029	3.695LeuLys: 3.695 ± 0.028	8.793LeuLeu: 8.793 ± 0.05	1.681LeuMet: 1.681 ± 0.016	2.826LeuAsn: 2.826 ± 0.023	6.622LeuPro: 6.622 ± 0.04	3.684LeuGln: 3.684 ± 0.028	6.634LeuArg: 6.634 ± 0.036	7.891LeuSer: 7.891 ± 0.041	5.159LeuThr: 5.159 ± 0.032	6.037LeuVal: 6.037 ± 0.037	1.278LeuTrp: 1.278 ± 0.016	2.429LeuTyr: 2.429 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	1.888MetAla: 1.888 ± 0.016	0.278MetCys: 0.278 ± 0.006	1.189MetAsp: 1.189 ± 0.016	1.111MetGlu: 1.111 ± 0.013	0.796MetPhe: 0.796 ± 0.012	1.23MetGly: 1.23 ± 0.016	0.597MetHis: 0.597 ± 0.011	0.843MetIle: 0.843 ± 0.013	0.843MetLys: 0.843 ± 0.012	1.922MetLeu: 1.922 ± 0.018	0.485MetMet: 0.485 ± 0.01	0.696MetAsn: 0.696 ± 0.012	1.404MetPro: 1.404 ± 0.016	0.849MetGln: 0.849 ± 0.012	1.418MetArg: 1.418 ± 0.014	2.065MetSer: 2.065 ± 0.018	1.214MetThr: 1.214 ± 0.015	1.217MetVal: 1.217 ± 0.014	0.282MetTrp: 0.282 ± 0.006	0.567MetTyr: 0.567 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.063AsnAla: 3.063 ± 0.025	0.383AsnCys: 0.383 ± 0.009	1.538AsnAsp: 1.538 ± 0.016	1.516AsnGlu: 1.516 ± 0.015	1.119AsnPhe: 1.119 ± 0.014	2.368AsnGly: 2.368 ± 0.027	0.692AsnHis: 0.692 ± 0.011	1.606AsnIle: 1.606 ± 0.015	1.105AsnLys: 1.105 ± 0.014	2.778AsnLeu: 2.778 ± 0.022	0.699AsnMet: 0.699 ± 0.01	1.02AsnAsn: 1.02 ± 0.014	2.181AsnPro: 2.181 ± 0.023	0.902AsnGln: 0.902 ± 0.012	1.574AsnArg: 1.574 ± 0.017	2.125AsnSer: 2.125 ± 0.019	1.825AsnThr: 1.825 ± 0.019	2.342AsnVal: 2.342 ± 0.02	0.463AsnTrp: 0.463 ± 0.01	0.816AsnTyr: 0.816 ± 0.011	0.0AsnXaa: 0.0 ± 0.0
Pro	6.527ProAla: 6.527 ± 0.051	0.679ProCys: 0.679 ± 0.012	3.494ProAsp: 3.494 ± 0.027	3.982ProGlu: 3.982 ± 0.029	2.255ProPhe: 2.255 ± 0.019	4.184ProGly: 4.184 ± 0.032	1.798ProHis: 1.798 ± 0.021	2.625ProIle: 2.625 ± 0.024	2.324ProLys: 2.324 ± 0.021	5.607ProLeu: 5.607 ± 0.036	1.179ProMet: 1.179 ± 0.015	2.02ProAsn: 2.02 ± 0.019	7.29ProPro: 7.29 ± 0.077	2.547ProGln: 2.547 ± 0.026	4.297ProArg: 4.297 ± 0.027	7.597ProSer: 7.597 ± 0.058	4.64ProThr: 4.64 ± 0.03	4.278ProVal: 4.278 ± 0.032	0.793ProTrp: 0.793 ± 0.011	1.663ProTyr: 1.663 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.372GlnAla: 3.372 ± 0.027	0.51GlnCys: 0.51 ± 0.009	1.859GlnAsp: 1.859 ± 0.018	2.128GlnGlu: 2.128 ± 0.019	1.207GlnPhe: 1.207 ± 0.014	2.139GlnGly: 2.139 ± 0.021	1.037GlnHis: 1.037 ± 0.015	1.446GlnIle: 1.446 ± 0.016	1.465GlnLys: 1.465 ± 0.018	3.336GlnLeu: 3.336 ± 0.026	0.768GlnMet: 0.768 ± 0.012	1.123GlnAsn: 1.123 ± 0.013	2.496GlnPro: 2.496 ± 0.025	1.853GlnGln: 1.853 ± 0.034	2.55GlnArg: 2.55 ± 0.024	2.822GlnSer: 2.822 ± 0.024	2.094GlnThr: 2.094 ± 0.019	2.141GlnVal: 2.141 ± 0.018	0.557GlnTrp: 0.557 ± 0.008	1.105GlnTyr: 1.105 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	5.893ArgAla: 5.893 ± 0.036	0.952ArgCys: 0.952 ± 0.013	3.49ArgAsp: 3.49 ± 0.027	3.96ArgGlu: 3.96 ± 0.031	2.167ArgPhe: 2.167 ± 0.02	3.948ArgGly: 3.948 ± 0.038	1.791ArgHis: 1.791 ± 0.018	2.919ArgIle: 2.919 ± 0.025	3.174ArgLys: 3.174 ± 0.028	6.005ArgLeu: 6.005 ± 0.036	1.511ArgMet: 1.511 ± 0.015	1.909ArgAsn: 1.909 ± 0.017	4.18ArgPro: 4.18 ± 0.03	2.331ArgGln: 2.331 ± 0.022	5.994ArgArg: 5.994 ± 0.044	5.363ArgSer: 5.363 ± 0.04	4.082ArgThr: 4.082 ± 0.031	4.039ArgVal: 4.039 ± 0.025	1.078ArgTrp: 1.078 ± 0.014	1.761ArgTyr: 1.761 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	7.657SerAla: 7.657 ± 0.046	1.062SerCys: 1.062 ± 0.018	4.268SerAsp: 4.268 ± 0.029	3.914SerGlu: 3.914 ± 0.032	2.933SerPhe: 2.933 ± 0.022	5.589SerGly: 5.589 ± 0.04	2.131SerHis: 2.131 ± 0.022	3.559SerIle: 3.559 ± 0.024	3.0SerLys: 3.0 ± 0.022	7.645SerLeu: 7.645 ± 0.045	1.737SerMet: 1.737 ± 0.021	2.365SerAsn: 2.365 ± 0.02	6.682SerPro: 6.682 ± 0.061	2.952SerGln: 2.952 ± 0.026	5.464SerArg: 5.464 ± 0.043	9.962SerSer: 9.962 ± 0.081	5.917SerThr: 5.917 ± 0.039	5.199SerVal: 5.199 ± 0.034	1.11SerTrp: 1.11 ± 0.013	1.959SerTyr: 1.959 ± 0.019	0.0SerXaa: 0.0 ± 0.0
Thr	5.336ThrAla: 5.336 ± 0.028	0.853ThrCys: 0.853 ± 0.013	2.775ThrAsp: 2.775 ± 0.021	2.755ThrGlu: 2.755 ± 0.022	2.447ThrPhe: 2.447 ± 0.021	3.86ThrGly: 3.86 ± 0.026	1.571ThrHis: 1.571 ± 0.016	2.853ThrIle: 2.853 ± 0.022	2.086ThrLys: 2.086 ± 0.019	5.911ThrLeu: 5.911 ± 0.028	1.173ThrMet: 1.173 ± 0.014	1.767ThrAsn: 1.767 ± 0.016	4.884ThrPro: 4.884 ± 0.035	1.945ThrGln: 1.945 ± 0.019	3.608ThrArg: 3.608 ± 0.027	5.671ThrSer: 5.671 ± 0.041	4.154ThrThr: 4.154 ± 0.034	4.051ThrVal: 4.051 ± 0.028	0.846ThrTrp: 0.846 ± 0.013	1.659ThrTyr: 1.659 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	5.822ValAla: 5.822 ± 0.037	0.992ValCys: 0.992 ± 0.013	3.944ValAsp: 3.944 ± 0.024	3.894ValGlu: 3.894 ± 0.027	2.571ValPhe: 2.571 ± 0.023	4.038ValGly: 4.038 ± 0.029	1.776ValHis: 1.776 ± 0.016	2.879ValIle: 2.879 ± 0.023	2.706ValLys: 2.706 ± 0.022	6.444ValLeu: 6.444 ± 0.036	1.322ValMet: 1.322 ± 0.014	2.054ValAsn: 2.054 ± 0.019	4.613ValPro: 4.613 ± 0.032	2.491ValGln: 2.491 ± 0.021	4.162ValArg: 4.162 ± 0.025	5.074ValSer: 5.074 ± 0.032	3.691ValThr: 3.691 ± 0.026	4.905ValVal: 4.905 ± 0.031	1.015ValTrp: 1.015 ± 0.015	1.842ValTyr: 1.842 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.162TrpAla: 1.162 ± 0.015	0.217TrpCys: 0.217 ± 0.006	0.919TrpAsp: 0.919 ± 0.014	0.838TrpGlu: 0.838 ± 0.012	0.568TrpPhe: 0.568 ± 0.009	0.871TrpGly: 0.871 ± 0.014	0.393TrpHis: 0.393 ± 0.007	0.696TrpIle: 0.696 ± 0.011	0.737TrpLys: 0.737 ± 0.011	1.334TrpLeu: 1.334 ± 0.016	0.37TrpMet: 0.37 ± 0.007	0.548TrpAsn: 0.548 ± 0.01	0.726TrpPro: 0.726 ± 0.01	0.553TrpGln: 0.553 ± 0.01	1.142TrpArg: 1.142 ± 0.015	1.098TrpSer: 1.098 ± 0.013	0.966TrpThr: 0.966 ± 0.014	0.889TrpVal: 0.889 ± 0.012	0.292TrpTrp: 0.292 ± 0.007	0.441TrpTyr: 0.441 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.397TyrAla: 2.397 ± 0.02	0.416TyrCys: 0.416 ± 0.008	1.653TyrAsp: 1.653 ± 0.016	1.415TyrGlu: 1.415 ± 0.015	1.084TyrPhe: 1.084 ± 0.013	1.942TyrGly: 1.942 ± 0.02	0.756TyrHis: 0.756 ± 0.011	1.316TyrIle: 1.316 ± 0.015	0.958TyrLys: 0.958 ± 0.014	2.498TyrLeu: 2.498 ± 0.023	0.569TyrMet: 0.569 ± 0.011	0.938TyrAsn: 0.938 ± 0.012	1.638TyrPro: 1.638 ± 0.019	0.919TyrGln: 0.919 ± 0.012	1.631TyrArg: 1.631 ± 0.018	1.894TyrSer: 1.894 ± 0.018	1.59TyrThr: 1.59 ± 0.016	1.837TyrVal: 1.837 ± 0.017	0.403TyrTrp: 0.403 ± 0.009	0.872TyrTyr: 0.872 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.001XaaXaa: 0.001 ± 0.001

Statistics based on 15512 proteins (6373336 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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