Amino acid dipepetide frequency for Mesitornis unicolor (brown roatelo)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.753AlaAla: 5.753 ± 0.049	1.313AlaCys: 1.313 ± 0.023	2.988AlaAsp: 2.988 ± 0.025	4.6AlaGlu: 4.6 ± 0.044	2.687AlaPhe: 2.687 ± 0.027	3.91AlaGly: 3.91 ± 0.043	1.35AlaHis: 1.35 ± 0.021	3.139AlaIle: 3.139 ± 0.034	3.769AlaLys: 3.769 ± 0.041	6.543AlaLeu: 6.543 ± 0.052	1.552AlaMet: 1.552 ± 0.022	2.225AlaAsn: 2.225 ± 0.028	2.959AlaPro: 2.959 ± 0.037	2.775AlaGln: 2.775 ± 0.034	2.983AlaArg: 2.983 ± 0.03	5.183AlaSer: 5.183 ± 0.045	3.361AlaThr: 3.361 ± 0.034	5.001AlaVal: 5.001 ± 0.041	0.7AlaTrp: 0.7 ± 0.015	1.657AlaTyr: 1.657 ± 0.025	0.0AlaXaa: 0.0 ± 0.0
Cys	1.16CysAla: 1.16 ± 0.019	0.666CysCys: 0.666 ± 0.017	1.05CysAsp: 1.05 ± 0.021	1.312CysGlu: 1.312 ± 0.028	0.916CysPhe: 0.916 ± 0.016	1.449CysGly: 1.449 ± 0.029	0.635CysHis: 0.635 ± 0.013	1.15CysIle: 1.15 ± 0.023	1.352CysLys: 1.352 ± 0.021	2.191CysLeu: 2.191 ± 0.028	0.47CysMet: 0.47 ± 0.013	0.924CysAsn: 0.924 ± 0.018	1.294CysPro: 1.294 ± 0.029	1.089CysGln: 1.089 ± 0.022	1.203CysArg: 1.203 ± 0.021	1.994CysSer: 1.994 ± 0.033	1.184CysThr: 1.184 ± 0.024	1.389CysVal: 1.389 ± 0.028	0.29CysTrp: 0.29 ± 0.01	0.689CysTyr: 0.689 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	2.978AspAla: 2.978 ± 0.029	1.092AspCys: 1.092 ± 0.022	2.884AspAsp: 2.884 ± 0.038	3.657AspGlu: 3.657 ± 0.037	2.271AspPhe: 2.271 ± 0.028	3.263AspGly: 3.263 ± 0.039	1.205AspHis: 1.205 ± 0.019	2.974AspIle: 2.974 ± 0.032	2.784AspLys: 2.784 ± 0.027	4.978AspLeu: 4.978 ± 0.041	1.143AspMet: 1.143 ± 0.018	1.938AspAsn: 1.938 ± 0.032	2.604AspPro: 2.604 ± 0.033	1.837AspGln: 1.837 ± 0.024	2.367AspArg: 2.367 ± 0.03	4.094AspSer: 4.094 ± 0.04	2.523AspThr: 2.523 ± 0.025	3.185AspVal: 3.185 ± 0.032	0.648AspTrp: 0.648 ± 0.015	1.669AspTyr: 1.669 ± 0.023	0.0AspXaa: 0.0 ± 0.0
Glu	4.658GluAla: 4.658 ± 0.044	1.312GluCys: 1.312 ± 0.033	4.488GluAsp: 4.488 ± 0.04	7.857GluGlu: 7.857 ± 0.091	2.239GluPhe: 2.239 ± 0.028	3.916GluGly: 3.916 ± 0.038	1.603GluHis: 1.603 ± 0.019	3.514GluIle: 3.514 ± 0.036	5.748GluLys: 5.748 ± 0.065	6.333GluLeu: 6.333 ± 0.061	1.803GluMet: 1.803 ± 0.025	3.429GluAsn: 3.429 ± 0.038	2.541GluPro: 2.541 ± 0.032	3.218GluGln: 3.218 ± 0.042	3.847GluArg: 3.847 ± 0.046	4.509GluSer: 4.509 ± 0.046	3.566GluThr: 3.566 ± 0.036	4.417GluVal: 4.417 ± 0.032	0.758GluTrp: 0.758 ± 0.014	1.825GluTyr: 1.825 ± 0.026	0.001GluXaa: 0.001 ± 0.0
Phe	2.203PheAla: 2.203 ± 0.027	1.019PheCys: 1.019 ± 0.018	1.826PheAsp: 1.826 ± 0.025	2.155PheGlu: 2.155 ± 0.024	1.908PhePhe: 1.908 ± 0.024	2.349PheGly: 2.349 ± 0.029	1.09PheHis: 1.09 ± 0.019	2.124PheIle: 2.124 ± 0.028	2.179PheLys: 2.179 ± 0.027	4.311PheLeu: 4.311 ± 0.045	0.813PheMet: 0.813 ± 0.019	1.559PheAsn: 1.559 ± 0.02	1.97PhePro: 1.97 ± 0.026	1.82PheGln: 1.82 ± 0.025	1.957PheArg: 1.957 ± 0.025	3.49PheSer: 3.49 ± 0.037	2.334PheThr: 2.334 ± 0.03	2.405PheVal: 2.405 ± 0.028	0.522PheTrp: 0.522 ± 0.013	1.351PheTyr: 1.351 ± 0.02	0.0PheXaa: 0.0 ± 0.0
Gly	3.54GlyAla: 3.54 ± 0.038	1.24GlyCys: 1.24 ± 0.022	2.927GlyAsp: 2.927 ± 0.038	3.756GlyGlu: 3.756 ± 0.05	2.569GlyPhe: 2.569 ± 0.037	3.848GlyGly: 3.848 ± 0.062	1.513GlyHis: 1.513 ± 0.023	3.082GlyIle: 3.082 ± 0.034	4.019GlyLys: 4.019 ± 0.043	5.22GlyLeu: 5.22 ± 0.055	1.41GlyMet: 1.41 ± 0.027	2.613GlyAsn: 2.613 ± 0.03	2.787GlyPro: 2.787 ± 0.085	2.504GlyGln: 2.504 ± 0.03	3.144GlyArg: 3.144 ± 0.037	4.997GlySer: 4.997 ± 0.052	3.383GlyThr: 3.383 ± 0.038	3.533GlyVal: 3.533 ± 0.035	0.768GlyTrp: 0.768 ± 0.017	1.888GlyTyr: 1.888 ± 0.03	0.001GlyXaa: 0.001 ± 0.001
His	1.313HisAla: 1.313 ± 0.02	0.719HisCys: 0.719 ± 0.015	0.906HisAsp: 0.906 ± 0.019	1.351HisGlu: 1.351 ± 0.018	1.104HisPhe: 1.104 ± 0.018	1.506HisGly: 1.506 ± 0.022	0.873HisHis: 0.873 ± 0.021	1.378HisIle: 1.378 ± 0.02	1.388HisLys: 1.388 ± 0.021	2.83HisLeu: 2.83 ± 0.032	0.591HisMet: 0.591 ± 0.013	0.992HisAsn: 0.992 ± 0.019	1.495HisPro: 1.495 ± 0.022	1.204HisGln: 1.204 ± 0.017	1.512HisArg: 1.512 ± 0.023	2.189HisSer: 2.189 ± 0.027	1.321HisThr: 1.321 ± 0.028	1.546HisVal: 1.546 ± 0.023	0.431HisTrp: 0.431 ± 0.012	0.873HisTyr: 0.873 ± 0.016	0.0HisXaa: 0.0 ± 0.0
Ile	3.071IleAla: 3.071 ± 0.032	1.222IleCys: 1.222 ± 0.023	2.324IleAsp: 2.324 ± 0.031	2.88IleGlu: 2.88 ± 0.034	2.199IlePhe: 2.199 ± 0.033	2.536IleGly: 2.536 ± 0.03	1.427IleHis: 1.427 ± 0.023	2.784IleIle: 2.784 ± 0.036	3.0IleLys: 3.0 ± 0.03	5.001IleLeu: 5.001 ± 0.044	1.068IleMet: 1.068 ± 0.021	2.166IleAsn: 2.166 ± 0.029	2.865IlePro: 2.865 ± 0.028	2.444IleGln: 2.444 ± 0.029	2.585IleArg: 2.585 ± 0.031	4.14IleSer: 4.14 ± 0.032	2.871IleThr: 2.871 ± 0.036	2.926IleVal: 2.926 ± 0.036	0.589IleTrp: 0.589 ± 0.013	1.658IleTyr: 1.658 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	4.201LysAla: 4.201 ± 0.046	1.242LysCys: 1.242 ± 0.023	3.462LysAsp: 3.462 ± 0.036	5.75LysGlu: 5.75 ± 0.065	1.99LysPhe: 1.99 ± 0.022	3.471LysGly: 3.471 ± 0.057	1.611LysHis: 1.611 ± 0.02	3.174LysIle: 3.174 ± 0.032	5.371LysLys: 5.371 ± 0.058	5.816LysLeu: 5.816 ± 0.046	1.55LysMet: 1.55 ± 0.018	2.761LysAsn: 2.761 ± 0.034	3.072LysPro: 3.072 ± 0.033	2.962LysGln: 2.962 ± 0.037	3.517LysArg: 3.517 ± 0.036	4.3LysSer: 4.3 ± 0.046	3.46LysThr: 3.46 ± 0.037	3.776LysVal: 3.776 ± 0.037	0.693LysTrp: 0.693 ± 0.013	1.9LysTyr: 1.9 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	6.27LeuAla: 6.27 ± 0.053	2.236LeuCys: 2.236 ± 0.029	4.906LeuAsp: 4.906 ± 0.04	7.07LeuGlu: 7.07 ± 0.072	3.607LeuPhe: 3.607 ± 0.04	5.277LeuGly: 5.277 ± 0.046	2.666LeuHis: 2.666 ± 0.033	4.302LeuIle: 4.302 ± 0.039	6.484LeuLys: 6.484 ± 0.06	10.129LeuLeu: 10.129 ± 0.089	2.046LeuMet: 2.046 ± 0.026	3.895LeuAsn: 3.895 ± 0.038	5.474LeuPro: 5.474 ± 0.053	5.722LeuGln: 5.722 ± 0.059	5.174LeuArg: 5.174 ± 0.039	7.855LeuSer: 7.855 ± 0.056	4.992LeuThr: 4.992 ± 0.044	5.526LeuVal: 5.526 ± 0.048	1.088LeuTrp: 1.088 ± 0.019	2.85LeuTyr: 2.85 ± 0.034	0.002LeuXaa: 0.002 ± 0.001
Met	1.662MetAla: 1.662 ± 0.025	0.466MetCys: 0.466 ± 0.013	1.294MetAsp: 1.294 ± 0.019	1.894MetGlu: 1.894 ± 0.027	0.851MetPhe: 0.851 ± 0.017	1.288MetGly: 1.288 ± 0.021	0.529MetHis: 0.529 ± 0.013	0.988MetIle: 0.988 ± 0.016	1.622MetLys: 1.622 ± 0.022	2.079MetLeu: 2.079 ± 0.025	0.602MetMet: 0.602 ± 0.013	1.026MetAsn: 1.026 ± 0.019	1.03MetPro: 1.03 ± 0.017	1.053MetGln: 1.053 ± 0.017	1.083MetArg: 1.083 ± 0.018	1.539MetSer: 1.539 ± 0.022	1.166MetThr: 1.166 ± 0.02	1.447MetVal: 1.447 ± 0.021	0.248MetTrp: 0.248 ± 0.008	0.673MetTyr: 0.673 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	2.375AsnAla: 2.375 ± 0.025	0.982AsnCys: 0.982 ± 0.019	1.712AsnAsp: 1.712 ± 0.027	2.574AsnGlu: 2.574 ± 0.03	1.673AsnPhe: 1.673 ± 0.023	2.782AsnGly: 2.782 ± 0.037	1.009AsnHis: 1.009 ± 0.019	2.497AsnIle: 2.497 ± 0.027	2.584AsnLys: 2.584 ± 0.031	4.142AsnLeu: 4.142 ± 0.041	1.005AsnMet: 1.005 ± 0.017	1.849AsnAsn: 1.849 ± 0.026	2.322AsnPro: 2.322 ± 0.03	1.727AsnGln: 1.727 ± 0.022	2.028AsnArg: 2.028 ± 0.025	3.431AsnSer: 3.431 ± 0.035	2.214AsnThr: 2.214 ± 0.028	2.495AsnVal: 2.495 ± 0.026	0.489AsnTrp: 0.489 ± 0.011	1.314AsnTyr: 1.314 ± 0.021	0.0AsnXaa: 0.0 ± 0.0
Pro	3.68ProAla: 3.68 ± 0.047	1.065ProCys: 1.065 ± 0.023	2.584ProAsp: 2.584 ± 0.028	3.843ProGlu: 3.843 ± 0.035	1.917ProPhe: 1.917 ± 0.025	3.704ProGly: 3.704 ± 0.112	1.242ProHis: 1.242 ± 0.022	1.982ProIle: 1.982 ± 0.024	2.739ProLys: 2.739 ± 0.034	4.627ProLeu: 4.627 ± 0.04	0.96ProMet: 0.96 ± 0.018	1.92ProAsn: 1.92 ± 0.027	4.197ProPro: 4.197 ± 0.083	2.328ProGln: 2.328 ± 0.034	2.554ProArg: 2.554 ± 0.03	5.021ProSer: 5.021 ± 0.053	2.645ProThr: 2.645 ± 0.028	3.773ProVal: 3.773 ± 0.034	0.562ProTrp: 0.562 ± 0.011	1.506ProTyr: 1.506 ± 0.021	0.0ProXaa: 0.0 ± 0.0
Gln	3.076GlnAla: 3.076 ± 0.035	0.978GlnCys: 0.978 ± 0.02	2.225GlnAsp: 2.225 ± 0.026	3.682GlnGlu: 3.682 ± 0.044	1.494GlnPhe: 1.494 ± 0.023	2.496GlnGly: 2.496 ± 0.036	1.302GlnHis: 1.302 ± 0.022	2.241GlnIle: 2.241 ± 0.024	3.185GlnLys: 3.185 ± 0.045	4.635GlnLeu: 4.635 ± 0.043	1.112GlnMet: 1.112 ± 0.021	2.063GlnAsn: 2.063 ± 0.024	2.355GlnPro: 2.355 ± 0.038	3.13GlnGln: 3.13 ± 0.07	2.62GlnArg: 2.62 ± 0.03	3.207GlnSer: 3.207 ± 0.037	2.395GlnThr: 2.395 ± 0.032	2.771GlnVal: 2.771 ± 0.03	0.522GlnTrp: 0.522 ± 0.013	1.333GlnTyr: 1.333 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	3.097ArgAla: 3.097 ± 0.032	1.123ArgCys: 1.123 ± 0.02	2.59ArgAsp: 2.59 ± 0.026	3.708ArgGlu: 3.708 ± 0.042	1.974ArgPhe: 1.974 ± 0.026	2.83ArgGly: 2.83 ± 0.041	1.466ArgHis: 1.466 ± 0.02	2.603ArgIle: 2.603 ± 0.026	3.931ArgLys: 3.931 ± 0.041	5.004ArgLeu: 5.004 ± 0.043	1.179ArgMet: 1.179 ± 0.014	2.252ArgAsn: 2.252 ± 0.028	2.383ArgPro: 2.383 ± 0.03	2.462ArgGln: 2.462 ± 0.029	3.665ArgArg: 3.665 ± 0.042	3.904ArgSer: 3.904 ± 0.048	2.677ArgThr: 2.677 ± 0.03	2.964ArgVal: 2.964 ± 0.032	0.62ArgTrp: 0.62 ± 0.015	1.589ArgTyr: 1.589 ± 0.021	0.001ArgXaa: 0.001 ± 0.0
Ser	5.143SerAla: 5.143 ± 0.047	1.836SerCys: 1.836 ± 0.026	3.996SerAsp: 3.996 ± 0.038	5.083SerGlu: 5.083 ± 0.051	3.148SerPhe: 3.148 ± 0.034	4.922SerGly: 4.922 ± 0.056	2.023SerHis: 2.023 ± 0.027	3.625SerIle: 3.625 ± 0.035	4.517SerLys: 4.517 ± 0.043	8.031SerLeu: 8.031 ± 0.054	1.647SerMet: 1.647 ± 0.024	3.061SerAsn: 3.061 ± 0.036	5.138SerPro: 5.138 ± 0.062	3.661SerGln: 3.661 ± 0.045	4.049SerArg: 4.049 ± 0.045	9.101SerSer: 9.101 ± 0.113	4.528SerThr: 4.528 ± 0.038	5.169SerVal: 5.169 ± 0.042	0.958SerTrp: 0.958 ± 0.016	2.27SerTyr: 2.27 ± 0.027	0.002SerXaa: 0.002 ± 0.001
Thr	3.899ThrAla: 3.899 ± 0.04	1.289ThrCys: 1.289 ± 0.026	2.717ThrAsp: 2.717 ± 0.031	3.76ThrGlu: 3.76 ± 0.031	2.225ThrPhe: 2.225 ± 0.031	3.425ThrGly: 3.425 ± 0.037	1.232ThrHis: 1.232 ± 0.026	2.581ThrIle: 2.581 ± 0.029	2.919ThrLys: 2.919 ± 0.029	5.151ThrLeu: 5.151 ± 0.039	1.136ThrMet: 1.136 ± 0.018	1.972ThrAsn: 1.972 ± 0.025	3.11ThrPro: 3.11 ± 0.037	2.155ThrGln: 2.155 ± 0.026	2.294ThrArg: 2.294 ± 0.023	4.615ThrSer: 4.615 ± 0.046	2.992ThrThr: 2.992 ± 0.043	4.134ThrVal: 4.134 ± 0.046	0.645ThrTrp: 0.645 ± 0.016	1.601ThrTyr: 1.601 ± 0.025	0.0ThrXaa: 0.0 ± 0.0
Val	4.093ValAla: 4.093 ± 0.035	1.584ValCys: 1.584 ± 0.031	3.084ValAsp: 3.084 ± 0.028	4.022ValGlu: 4.022 ± 0.035	2.726ValPhe: 2.726 ± 0.037	3.352ValGly: 3.352 ± 0.034	1.58ValHis: 1.58 ± 0.021	3.291ValIle: 3.291 ± 0.035	3.852ValLys: 3.852 ± 0.031	6.391ValLeu: 6.391 ± 0.054	1.449ValMet: 1.449 ± 0.022	2.622ValAsn: 2.622 ± 0.027	3.44ValPro: 3.44 ± 0.031	2.841ValGln: 2.841 ± 0.031	3.05ValArg: 3.05 ± 0.031	5.027ValSer: 5.027 ± 0.042	3.902ValThr: 3.902 ± 0.036	4.344ValVal: 4.344 ± 0.042	0.723ValTrp: 0.723 ± 0.017	1.902ValTyr: 1.902 ± 0.029	0.0ValXaa: 0.0 ± 0.0
Trp	0.666TrpAla: 0.666 ± 0.016	0.243TrpCys: 0.243 ± 0.009	0.667TrpAsp: 0.667 ± 0.017	0.766TrpGlu: 0.766 ± 0.014	0.459TrpPhe: 0.459 ± 0.012	0.645TrpGly: 0.645 ± 0.018	0.349TrpHis: 0.349 ± 0.01	0.626TrpIle: 0.626 ± 0.015	0.886TrpLys: 0.886 ± 0.017	1.185TrpLeu: 1.185 ± 0.02	0.311TrpMet: 0.311 ± 0.009	0.629TrpAsn: 0.629 ± 0.015	0.446TrpPro: 0.446 ± 0.011	0.547TrpGln: 0.547 ± 0.012	0.653TrpArg: 0.653 ± 0.013	0.877TrpSer: 0.877 ± 0.017	0.666TrpThr: 0.666 ± 0.014	0.669TrpVal: 0.669 ± 0.013	0.19TrpTrp: 0.19 ± 0.007	0.376TrpTyr: 0.376 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.611TyrAla: 1.611 ± 0.022	0.782TyrCys: 0.782 ± 0.016	1.464TyrAsp: 1.464 ± 0.024	1.863TyrGlu: 1.863 ± 0.024	1.429TyrPhe: 1.429 ± 0.019	1.771TyrGly: 1.771 ± 0.023	0.817TyrHis: 0.817 ± 0.017	1.699TyrIle: 1.699 ± 0.024	1.747TyrLys: 1.747 ± 0.024	2.973TyrLeu: 2.973 ± 0.034	0.695TyrMet: 0.695 ± 0.013	1.311TyrAsn: 1.311 ± 0.021	1.365TyrPro: 1.365 ± 0.019	1.345TyrGln: 1.345 ± 0.02	1.735TyrArg: 1.735 ± 0.025	2.434TyrSer: 2.434 ± 0.028	1.668TyrThr: 1.668 ± 0.026	1.804TyrVal: 1.804 ± 0.028	0.412TyrTrp: 0.412 ± 0.012	1.124TyrTyr: 1.124 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.001XaaLeu: 0.001 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.001	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.035XaaXaa: 0.035 ± 0.007

Statistics based on 9395 proteins (3786929 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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