Canine circovirus

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Arfiviricetes; Cirlivirales; Circoviridae; Circovirus

Average proteome isoelectric point is 8.43

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A3Q8CUM1|A0A3Q8CUM1_9CIRC Capsid protein OS=Canine circovirus OX=1194757 PE=3 SV=1
MM1 pKa = 7.39AQAQVDD7 pKa = 3.48QGVRR11 pKa = 11.84DD12 pKa = 3.83SRR14 pKa = 11.84RR15 pKa = 11.84GNPVRR20 pKa = 11.84RR21 pKa = 11.84WCFTINNPTPAEE33 pKa = 3.81EE34 pKa = 4.25DD35 pKa = 3.35AVKK38 pKa = 10.89NLAPDD43 pKa = 3.86AKK45 pKa = 10.76YY46 pKa = 10.33LICGRR51 pKa = 11.84EE52 pKa = 3.93VGEE55 pKa = 4.53NGTPHH60 pKa = 6.46LQGFVNLKK68 pKa = 8.03NTTRR72 pKa = 11.84MGALKK77 pKa = 10.49ARR79 pKa = 11.84LGGRR83 pKa = 11.84GHH85 pKa = 6.8FEE87 pKa = 3.62PARR90 pKa = 11.84GDD92 pKa = 3.42DD93 pKa = 3.67CSNRR97 pKa = 11.84DD98 pKa = 3.58YY99 pKa = 11.06CSKK102 pKa = 11.13GGDD105 pKa = 3.69LLIEE109 pKa = 4.42SGEE112 pKa = 3.9PSKK115 pKa = 10.75QGKK118 pKa = 10.02RR119 pKa = 11.84NDD121 pKa = 3.19LHH123 pKa = 6.96DD124 pKa = 4.28AVVKK128 pKa = 10.85LKK130 pKa = 8.03EE131 pKa = 4.51TKK133 pKa = 10.42SLAAVAAAYY142 pKa = 9.45PEE144 pKa = 4.57TYY146 pKa = 10.78VKK148 pKa = 10.49FSRR151 pKa = 11.84GLRR154 pKa = 11.84EE155 pKa = 4.22LLLISPEE162 pKa = 3.9MTTPRR167 pKa = 11.84NWKK170 pKa = 8.16TEE172 pKa = 3.85VEE174 pKa = 4.7VLCGPPGCGKK184 pKa = 10.1SRR186 pKa = 11.84YY187 pKa = 9.7CMEE190 pKa = 4.59TAPNAYY196 pKa = 7.64WKK198 pKa = 10.11PRR200 pKa = 11.84GKK202 pKa = 8.99WWDD205 pKa = 3.98GYY207 pKa = 11.04DD208 pKa = 3.33GHH210 pKa = 7.7QDD212 pKa = 3.46VILDD216 pKa = 4.51DD217 pKa = 4.32FYY219 pKa = 11.95GWLPFDD225 pKa = 4.98DD226 pKa = 4.55MLRR229 pKa = 11.84LLDD232 pKa = 4.47RR233 pKa = 11.84YY234 pKa = 9.16PLRR237 pKa = 11.84VEE239 pKa = 4.44TKK241 pKa = 8.53GGTMNFVARR250 pKa = 11.84RR251 pKa = 11.84VFITSNRR258 pKa = 11.84LPHH261 pKa = 6.17EE262 pKa = 4.52WYY264 pKa = 10.4SDD266 pKa = 3.55EE267 pKa = 4.55IGNKK271 pKa = 7.53EE272 pKa = 3.65ALYY275 pKa = 10.68RR276 pKa = 11.84RR277 pKa = 11.84LTLIKK282 pKa = 10.32VWDD285 pKa = 4.28GGNFIPVPHH294 pKa = 6.61FMFPHH299 pKa = 6.5MYY301 pKa = 10.46NYY303 pKa = 11.11

Molecular weight: 34.52 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A3Q8CUM1|A0A3Q8CUM1_9CIRC Capsid protein OS=Canine circovirus OX=1194757 PE=3 SV=1
MM1 pKa = 7.64RR2 pKa = 11.84VRR4 pKa = 11.84RR5 pKa = 11.84HH6 pKa = 4.17VRR8 pKa = 11.84ASRR11 pKa = 11.84RR12 pKa = 11.84RR13 pKa = 11.84FRR15 pKa = 11.84TRR17 pKa = 11.84PLNRR21 pKa = 11.84YY22 pKa = 7.83RR23 pKa = 11.84RR24 pKa = 11.84RR25 pKa = 11.84RR26 pKa = 11.84QNNFKK31 pKa = 10.55LFHH34 pKa = 6.01LRR36 pKa = 11.84LRR38 pKa = 11.84RR39 pKa = 11.84TLTADD44 pKa = 2.88WPTAPLKK51 pKa = 8.78PTNDD55 pKa = 3.59PTTEE59 pKa = 4.41TPLLWNFDD67 pKa = 3.74HH68 pKa = 7.54LSFKK72 pKa = 10.43LTDD75 pKa = 4.09FLQASHH81 pKa = 6.14GTGDD85 pKa = 4.02FQHH88 pKa = 6.97LPPFRR93 pKa = 11.84YY94 pKa = 9.12FKK96 pKa = 10.55FKK98 pKa = 10.46KK99 pKa = 10.01VYY101 pKa = 10.21VRR103 pKa = 11.84AKK105 pKa = 8.71WINWPRR111 pKa = 11.84NMMEE115 pKa = 4.0NVLGRR120 pKa = 11.84TALDD124 pKa = 4.38LDD126 pKa = 4.86GEE128 pKa = 4.39DD129 pKa = 3.44QGRR132 pKa = 11.84GNATRR137 pKa = 11.84SHH139 pKa = 7.44LDD141 pKa = 3.13PGTVPGINQPPKK153 pKa = 10.53DD154 pKa = 3.81PNKK157 pKa = 10.78APFIYY162 pKa = 10.39DD163 pKa = 3.56PLQDD167 pKa = 3.52RR168 pKa = 11.84TSSRR172 pKa = 11.84SFNMALGFKK181 pKa = 10.27RR182 pKa = 11.84GLTPKK187 pKa = 10.44PMFTQEE193 pKa = 3.88IQSPSATAPWLTRR206 pKa = 11.84GTPWISVIQGANMVWNGLSISLRR229 pKa = 11.84QMKK232 pKa = 10.27DD233 pKa = 3.03MRR235 pKa = 11.84PTTAEE240 pKa = 4.01TATSQIPQVQYY251 pKa = 10.95DD252 pKa = 3.6ISAYY256 pKa = 9.63IAFKK260 pKa = 10.77EE261 pKa = 3.83FDD263 pKa = 4.01YY264 pKa = 10.05EE265 pKa = 4.2TGRR268 pKa = 11.84QLL270 pKa = 4.35

Molecular weight: 31.51 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2

0

2

573

270

303

286.5

33.01

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.108 ± 0.124

1.222 ± 0.833

6.108 ± 0.377

4.363 ± 1.208

4.712 ± 0.828

7.33 ± 1.463

2.269 ± 0.032

3.316 ± 0.265

5.41 ± 0.406

8.551 ± 0.022

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.792 ± 0.116

5.236 ± 0.034

7.504 ± 0.692

3.49 ± 1.156

9.599 ± 1.032

4.363 ± 0.561

6.806 ± 1.421

4.712 ± 0.941

2.618 ± 0.017

3.49 ± 0.612
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski