Retroperitoneal fibromatosis-associated herpesvirus

Taxonomy: Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Herpesviridae; Gammaherpesvirinae; Rhadinovirus; Macacine gammaherpesvirus 8

Average proteome isoelectric point is 6.82

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 82 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A9JPH4|A9JPH4_9GAMA Interleukin 6 OS=Retroperitoneal fibromatosis-associated herpesvirus OX=111469 PE=3 SV=1
MM1 pKa = 7.86AGRR4 pKa = 11.84GMQLRR9 pKa = 11.84SGRR12 pKa = 11.84TTGDD16 pKa = 3.2PEE18 pKa = 4.28EE19 pKa = 4.56GHH21 pKa = 6.43MSTKK25 pKa = 10.35RR26 pKa = 11.84CLPPDD31 pKa = 3.93DD32 pKa = 4.3RR33 pKa = 11.84AQGARR38 pKa = 11.84QARR41 pKa = 11.84KK42 pKa = 8.88RR43 pKa = 11.84RR44 pKa = 11.84KK45 pKa = 10.04GYY47 pKa = 9.17GAPVGTGEE55 pKa = 4.18PTIPSAPPASPPASTSAAPPASPSAPLASTSAAPPALPPASPSAPPASPSAPPASPPAPPASPPASPSAPPAPPAPPASPSAPPASPSGSPSPASPQVSPSASSALPSAPLASPSDD171 pKa = 3.88PDD173 pKa = 3.86APTPGPSLTVRR184 pKa = 11.84PGTPWPTTWHH194 pKa = 6.76PGSKK198 pKa = 9.93RR199 pKa = 11.84PAPSLQGSPPCKK211 pKa = 9.37LAKK214 pKa = 8.7PTWLPGSPSMDD225 pKa = 3.04SSPEE229 pKa = 3.91MFLSPPTGPDD239 pKa = 2.63GGFYY243 pKa = 10.57LPCPVTSTPHH253 pKa = 4.9VCQSEE258 pKa = 4.47PIVIGSSSEE267 pKa = 3.8DD268 pKa = 3.63DD269 pKa = 3.63NLGGLSPISVGSSSSEE285 pKa = 3.86SSDD288 pKa = 3.04EE289 pKa = 3.84RR290 pKa = 11.84RR291 pKa = 11.84GILLRR296 pKa = 11.84LLAEE300 pKa = 4.57IADD303 pKa = 4.04EE304 pKa = 4.15VDD306 pKa = 4.71DD307 pKa = 5.25RR308 pKa = 11.84NEE310 pKa = 4.02GQDD313 pKa = 3.29NNRR316 pKa = 11.84PLTRR320 pKa = 11.84EE321 pKa = 3.83AKK323 pKa = 10.47LEE325 pKa = 4.15EE326 pKa = 4.77GSDD329 pKa = 3.73VEE331 pKa = 5.65SDD333 pKa = 4.63DD334 pKa = 4.07EE335 pKa = 4.59PEE337 pKa = 4.41SEE339 pKa = 4.69GEE341 pKa = 4.05PEE343 pKa = 4.11PEE345 pKa = 4.18EE346 pKa = 3.97EE347 pKa = 4.56TEE349 pKa = 4.28PEE351 pKa = 4.13PEE353 pKa = 4.29PEE355 pKa = 4.17PEE357 pKa = 4.23EE358 pKa = 4.14EE359 pKa = 4.62PEE361 pKa = 4.28PEE363 pKa = 4.27PEE365 pKa = 4.28PEE367 pKa = 4.16PEE369 pKa = 4.36EE370 pKa = 4.09EE371 pKa = 4.61PEE373 pKa = 4.2PKK375 pKa = 9.91PEE377 pKa = 4.29PEE379 pKa = 4.07QEE381 pKa = 4.18PEE383 pKa = 4.07PEE385 pKa = 4.26EE386 pKa = 4.13EE387 pKa = 4.66PEE389 pKa = 4.28PEE391 pKa = 4.27PEE393 pKa = 4.28PEE395 pKa = 4.16PEE397 pKa = 4.23EE398 pKa = 4.14EE399 pKa = 4.48PEE401 pKa = 4.2PEE403 pKa = 4.23PEE405 pKa = 4.2EE406 pKa = 4.12EE407 pKa = 4.28PKK409 pKa = 10.57PEE411 pKa = 4.21PEE413 pKa = 4.03QEE415 pKa = 4.08PEE417 pKa = 4.2EE418 pKa = 4.26EE419 pKa = 4.36PKK421 pKa = 10.4SEE423 pKa = 4.24PEE425 pKa = 3.99PEE427 pKa = 4.24PEE429 pKa = 4.11EE430 pKa = 4.56EE431 pKa = 4.28PDD433 pKa = 3.82SEE435 pKa = 4.72EE436 pKa = 3.89EE437 pKa = 4.34TEE439 pKa = 4.43PEE441 pKa = 4.14PEE443 pKa = 4.16PEE445 pKa = 4.25EE446 pKa = 4.14EE447 pKa = 4.48PEE449 pKa = 4.2PEE451 pKa = 4.17PEE453 pKa = 4.21EE454 pKa = 4.14EE455 pKa = 4.48PEE457 pKa = 4.24PEE459 pKa = 4.16PEE461 pKa = 4.29EE462 pKa = 4.72KK463 pKa = 10.37PEE465 pKa = 3.91QGPEE469 pKa = 3.97EE470 pKa = 4.2EE471 pKa = 5.0PEE473 pKa = 4.21PEE475 pKa = 4.1PEE477 pKa = 4.12EE478 pKa = 4.2EE479 pKa = 4.36PEE481 pKa = 4.13EE482 pKa = 4.18EE483 pKa = 4.66PEE485 pKa = 4.29PEE487 pKa = 4.42PEE489 pKa = 4.28PEE491 pKa = 4.7PGPEE495 pKa = 4.07EE496 pKa = 4.07EE497 pKa = 4.93PEE499 pKa = 4.35PGPEE503 pKa = 4.05EE504 pKa = 4.07EE505 pKa = 4.93PEE507 pKa = 4.35PGPEE511 pKa = 3.97EE512 pKa = 4.13EE513 pKa = 5.07PGPEE517 pKa = 4.05PEE519 pKa = 4.84EE520 pKa = 4.11EE521 pKa = 4.16PKK523 pKa = 10.57PEE525 pKa = 4.21PEE527 pKa = 4.03QEE529 pKa = 4.08PEE531 pKa = 4.2EE532 pKa = 4.26EE533 pKa = 4.36PKK535 pKa = 10.4SEE537 pKa = 4.24PEE539 pKa = 3.99PEE541 pKa = 4.24PEE543 pKa = 4.11EE544 pKa = 4.56EE545 pKa = 4.28PDD547 pKa = 3.82SEE549 pKa = 4.72EE550 pKa = 3.89EE551 pKa = 4.34TEE553 pKa = 4.43PEE555 pKa = 4.14PEE557 pKa = 4.16PEE559 pKa = 4.25EE560 pKa = 4.14EE561 pKa = 4.48PEE563 pKa = 4.2PEE565 pKa = 4.17PEE567 pKa = 4.21EE568 pKa = 4.14EE569 pKa = 4.48PEE571 pKa = 4.24PEE573 pKa = 4.22PEE575 pKa = 4.23EE576 pKa = 4.44KK577 pKa = 10.4PEE579 pKa = 4.17PEE581 pKa = 4.2PEE583 pKa = 4.07EE584 pKa = 4.13EE585 pKa = 4.48PEE587 pKa = 4.2PEE589 pKa = 4.17PEE591 pKa = 4.21EE592 pKa = 4.14EE593 pKa = 4.48PEE595 pKa = 4.2PEE597 pKa = 4.17PEE599 pKa = 4.21EE600 pKa = 4.14EE601 pKa = 4.48PEE603 pKa = 4.2PEE605 pKa = 4.17PEE607 pKa = 4.21EE608 pKa = 4.14EE609 pKa = 4.48PEE611 pKa = 4.2PEE613 pKa = 4.17PEE615 pKa = 4.21EE616 pKa = 4.14EE617 pKa = 4.48PEE619 pKa = 4.2PEE621 pKa = 4.17PEE623 pKa = 4.21EE624 pKa = 4.14EE625 pKa = 4.48PEE627 pKa = 4.2PEE629 pKa = 4.17PEE631 pKa = 4.21EE632 pKa = 4.14EE633 pKa = 4.48PEE635 pKa = 4.2PEE637 pKa = 4.17PEE639 pKa = 4.21EE640 pKa = 4.14EE641 pKa = 4.48PEE643 pKa = 4.2PEE645 pKa = 4.17PEE647 pKa = 4.21EE648 pKa = 4.14EE649 pKa = 4.48PEE651 pKa = 4.2PEE653 pKa = 4.17PEE655 pKa = 4.21EE656 pKa = 4.14EE657 pKa = 4.48PEE659 pKa = 4.2PEE661 pKa = 4.17PEE663 pKa = 4.21EE664 pKa = 4.14EE665 pKa = 4.48PEE667 pKa = 4.2PEE669 pKa = 4.17PEE671 pKa = 4.21EE672 pKa = 4.14EE673 pKa = 4.48PEE675 pKa = 4.2PEE677 pKa = 4.17PEE679 pKa = 4.21EE680 pKa = 4.14EE681 pKa = 4.62PEE683 pKa = 4.23PEE685 pKa = 4.27PEE687 pKa = 4.15PEE689 pKa = 4.23EE690 pKa = 4.14EE691 pKa = 4.88PEE693 pKa = 4.37PEE695 pKa = 4.11PQPEE699 pKa = 4.24EE700 pKa = 4.04EE701 pKa = 4.79PEE703 pKa = 4.17PEE705 pKa = 4.17PEE707 pKa = 4.21EE708 pKa = 4.14EE709 pKa = 4.48PEE711 pKa = 4.2PEE713 pKa = 4.17PEE715 pKa = 4.21EE716 pKa = 4.14EE717 pKa = 4.48PEE719 pKa = 4.2PEE721 pKa = 4.17PEE723 pKa = 4.21EE724 pKa = 4.14EE725 pKa = 4.48PEE727 pKa = 4.2PEE729 pKa = 4.17PEE731 pKa = 4.21EE732 pKa = 4.14EE733 pKa = 4.48PEE735 pKa = 4.2PEE737 pKa = 4.17PEE739 pKa = 4.21EE740 pKa = 4.14EE741 pKa = 4.62PEE743 pKa = 4.23PEE745 pKa = 4.27PEE747 pKa = 4.15PEE749 pKa = 4.23EE750 pKa = 4.14EE751 pKa = 4.88PEE753 pKa = 4.37PEE755 pKa = 4.11PQPEE759 pKa = 4.24EE760 pKa = 4.04EE761 pKa = 4.79PEE763 pKa = 4.17PEE765 pKa = 4.17PEE767 pKa = 4.21EE768 pKa = 4.14EE769 pKa = 4.48PEE771 pKa = 4.2PEE773 pKa = 4.17PEE775 pKa = 4.21EE776 pKa = 4.14EE777 pKa = 4.63PEE779 pKa = 4.17PEE781 pKa = 4.11PEE783 pKa = 4.42KK784 pKa = 10.84EE785 pKa = 4.21PEE787 pKa = 4.19PEE789 pKa = 4.0PEE791 pKa = 4.14EE792 pKa = 4.2EE793 pKa = 4.27PEE795 pKa = 4.08EE796 pKa = 4.21EE797 pKa = 4.41PEE799 pKa = 4.13EE800 pKa = 4.18EE801 pKa = 4.66PEE803 pKa = 4.23PEE805 pKa = 4.27PEE807 pKa = 4.15PEE809 pKa = 4.23EE810 pKa = 4.14EE811 pKa = 4.48PEE813 pKa = 4.2PEE815 pKa = 4.17PEE817 pKa = 4.21EE818 pKa = 4.14EE819 pKa = 4.62PEE821 pKa = 4.28PEE823 pKa = 4.42PEE825 pKa = 4.3PEE827 pKa = 4.29PEE829 pKa = 4.16PEE831 pKa = 4.23EE832 pKa = 4.14EE833 pKa = 4.57PEE835 pKa = 4.16PEE837 pKa = 4.63PEE839 pKa = 4.51DD840 pKa = 3.51EE841 pKa = 4.85HH842 pKa = 8.8EE843 pKa = 4.73EE844 pKa = 4.07EE845 pKa = 5.26PEE847 pKa = 3.91PQEE850 pKa = 5.64PEE852 pKa = 4.12DD853 pKa = 5.1SDD855 pKa = 4.28NADD858 pKa = 3.88ANTQEE863 pKa = 4.13PSEE866 pKa = 4.37VNEE869 pKa = 4.12PVPPEE874 pKa = 4.26PEE876 pKa = 4.37SNPEE880 pKa = 3.39PSYY883 pKa = 11.59AVINVDD889 pKa = 3.19SGPRR893 pKa = 11.84PVVRR897 pKa = 11.84LRR899 pKa = 11.84RR900 pKa = 11.84VPGGNGGRR908 pKa = 11.84PPFHH912 pKa = 7.37ARR914 pKa = 11.84FQSPMMPYY922 pKa = 8.42QTPDD926 pKa = 2.77GCPPKK931 pKa = 10.45ARR933 pKa = 11.84PLHH936 pKa = 5.93RR937 pKa = 11.84FYY939 pKa = 11.43LRR941 pKa = 11.84FLGPLTMYY949 pKa = 10.61RR950 pKa = 11.84PDD952 pKa = 3.33RR953 pKa = 11.84HH954 pKa = 5.58WRR956 pKa = 11.84HH957 pKa = 5.89AAIFWTPRR965 pKa = 11.84PYY967 pKa = 10.17PLKK970 pKa = 10.91KK971 pKa = 9.34MAQALQFGGIRR982 pKa = 11.84CGPVTCLPHH991 pKa = 6.72PGRR994 pKa = 11.84PGVPGPHH1001 pKa = 6.59MYY1003 pKa = 10.46CIYY1006 pKa = 10.62VYY1008 pKa = 9.98CQSKK1012 pKa = 8.46ATAQKK1017 pKa = 10.6VILGRR1022 pKa = 11.84EE1023 pKa = 3.87AWEE1026 pKa = 4.39ANHH1029 pKa = 6.03GAAVILEE1036 pKa = 4.03SSRR1039 pKa = 11.84VKK1041 pKa = 10.84FKK1043 pKa = 11.48DD1044 pKa = 3.53SMPLNLGSLPPPAPTSPPHH1063 pKa = 6.65SNASQEE1069 pKa = 4.25TEE1071 pKa = 3.63

Molecular weight: 117.76 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|U5NM51|U5NM51_9GAMA ORF30 OS=Retroperitoneal fibromatosis-associated herpesvirus OX=111469 PE=3 SV=1
MM1 pKa = 7.91ADD3 pKa = 3.94GSPTTAACGGHH14 pKa = 6.83DD15 pKa = 4.56PEE17 pKa = 5.77PPSDD21 pKa = 3.59YY22 pKa = 10.95VVPNDD27 pKa = 4.24SPQKK31 pKa = 7.54TLPRR35 pKa = 11.84IVRR38 pKa = 11.84MPTRR42 pKa = 11.84RR43 pKa = 11.84LCPTPYY49 pKa = 10.45LPVPPSVRR57 pKa = 11.84GPSPLKK63 pKa = 10.58ASPCYY68 pKa = 10.38TMLSPLSGPRR78 pKa = 11.84GLTDD82 pKa = 4.0GAPAARR88 pKa = 11.84SPAAPEE94 pKa = 3.95VEE96 pKa = 4.18PVQLPQHH103 pKa = 6.62GSPSPTAQHH112 pKa = 6.75KK113 pKa = 10.43LPSFHH118 pKa = 7.41YY119 pKa = 10.26IEE121 pKa = 4.43TPRR124 pKa = 11.84IRR126 pKa = 11.84PLGEE130 pKa = 4.13GSPTPPLAASATLPAGPQTSSTGDD154 pKa = 3.04SDD156 pKa = 4.32AEE158 pKa = 4.05RR159 pKa = 11.84GGDD162 pKa = 4.01RR163 pKa = 11.84NTQSTNPLNKK173 pKa = 8.37PQRR176 pKa = 11.84GRR178 pKa = 11.84RR179 pKa = 11.84RR180 pKa = 11.84RR181 pKa = 11.84VKK183 pKa = 9.32LVRR186 pKa = 11.84RR187 pKa = 11.84VRR189 pKa = 11.84IRR191 pKa = 11.84RR192 pKa = 11.84RR193 pKa = 11.84GSGGSSPKK201 pKa = 10.46NGEE204 pKa = 4.2ATDD207 pKa = 4.06SPPTSS212 pKa = 3.36

Molecular weight: 22.34 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

82

0

82

37788

63

2604

460.8

51.03

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

8.487 ± 0.288

2.448 ± 0.162

4.623 ± 0.19

5.809 ± 0.779

3.988 ± 0.16

6.052 ± 0.2

2.744 ± 0.115

4.425 ± 0.164

3.348 ± 0.152

10.255 ± 0.343

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.979 ± 0.109

3.207 ± 0.144

7.299 ± 0.653

3.866 ± 0.246

6.224 ± 0.225

7.164 ± 0.298

6.883 ± 0.317

6.933 ± 0.274

1.238 ± 0.084

3.027 ± 0.142
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski