Amino acid dipepetide frequency for Tritonibacter horizontis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.729AlaAla: 16.729 ± 0.171	1.129AlaCys: 1.129 ± 0.029	6.931AlaAsp: 6.931 ± 0.073	8.238AlaGlu: 8.238 ± 0.081	4.187AlaPhe: 4.187 ± 0.061	10.092AlaGly: 10.092 ± 0.088	2.295AlaHis: 2.295 ± 0.043	5.654AlaIle: 5.654 ± 0.06	3.721AlaLys: 3.721 ± 0.065	13.828AlaLeu: 13.828 ± 0.131	3.665AlaMet: 3.665 ± 0.05	2.689AlaAsn: 2.689 ± 0.049	5.801AlaPro: 5.801 ± 0.086	4.927AlaGln: 4.927 ± 0.06	8.678AlaArg: 8.678 ± 0.098	5.711AlaSer: 5.711 ± 0.053	6.15AlaThr: 6.15 ± 0.064	8.188AlaVal: 8.188 ± 0.083	1.351AlaTrp: 1.351 ± 0.038	2.531AlaTyr: 2.531 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	1.145CysAla: 1.145 ± 0.033	0.127CysCys: 0.127 ± 0.01	0.669CysAsp: 0.669 ± 0.022	0.434CysGlu: 0.434 ± 0.018	0.383CysPhe: 0.383 ± 0.017	0.901CysGly: 0.901 ± 0.028	0.315CysHis: 0.315 ± 0.016	0.431CysIle: 0.431 ± 0.016	0.22CysLys: 0.22 ± 0.011	0.934CysLeu: 0.934 ± 0.026	0.176CysMet: 0.176 ± 0.011	0.229CysAsn: 0.229 ± 0.011	0.505CysPro: 0.505 ± 0.02	0.264CysGln: 0.264 ± 0.014	0.588CysArg: 0.588 ± 0.023	0.466CysSer: 0.466 ± 0.018	0.48CysThr: 0.48 ± 0.017	0.658CysVal: 0.658 ± 0.025	0.125CysTrp: 0.125 ± 0.01	0.222CysTyr: 0.222 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	7.017AspAla: 7.017 ± 0.075	0.57AspCys: 0.57 ± 0.02	3.416AspAsp: 3.416 ± 0.077	3.19AspGlu: 3.19 ± 0.057	2.376AspPhe: 2.376 ± 0.043	5.356AspGly: 5.356 ± 0.071	1.469AspHis: 1.469 ± 0.033	3.173AspIle: 3.173 ± 0.047	1.731AspLys: 1.731 ± 0.039	6.989AspLeu: 6.989 ± 0.076	1.661AspMet: 1.661 ± 0.036	1.304AspAsn: 1.304 ± 0.033	3.58AspPro: 3.58 ± 0.051	2.136AspGln: 2.136 ± 0.039	4.319AspArg: 4.319 ± 0.062	2.48AspSer: 2.48 ± 0.04	3.053AspThr: 3.053 ± 0.057	4.361AspVal: 4.361 ± 0.06	1.17AspTrp: 1.17 ± 0.034	1.534AspTyr: 1.534 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	7.903GluAla: 7.903 ± 0.082	0.348GluCys: 0.348 ± 0.018	3.445GluAsp: 3.445 ± 0.051	3.469GluGlu: 3.469 ± 0.059	1.816GluPhe: 1.816 ± 0.036	4.463GluGly: 4.463 ± 0.059	1.067GluHis: 1.067 ± 0.031	3.92GluIle: 3.92 ± 0.055	2.031GluLys: 2.031 ± 0.042	5.244GluLeu: 5.244 ± 0.063	1.795GluMet: 1.795 ± 0.039	1.756GluAsn: 1.756 ± 0.037	2.329GluPro: 2.329 ± 0.041	2.122GluGln: 2.122 ± 0.039	4.001GluArg: 4.001 ± 0.055	2.153GluSer: 2.153 ± 0.043	4.07GluThr: 4.07 ± 0.053	4.461GluVal: 4.461 ± 0.056	0.657GluTrp: 0.657 ± 0.021	1.004GluTyr: 1.004 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	4.548PheAla: 4.548 ± 0.055	0.481PheCys: 0.481 ± 0.019	2.955PheAsp: 2.955 ± 0.045	2.232PheGlu: 2.232 ± 0.044	1.456PhePhe: 1.456 ± 0.042	3.706PheGly: 3.706 ± 0.055	0.771PheHis: 0.771 ± 0.024	1.562PheIle: 1.562 ± 0.036	1.0PheLys: 1.0 ± 0.032	3.527PheLeu: 3.527 ± 0.053	0.824PheMet: 0.824 ± 0.026	1.087PheAsn: 1.087 ± 0.03	1.506PhePro: 1.506 ± 0.036	1.173PheGln: 1.173 ± 0.03	2.104PheArg: 2.104 ± 0.035	2.215PheSer: 2.215 ± 0.04	1.968PheThr: 1.968 ± 0.037	2.742PheVal: 2.742 ± 0.046	0.551PheTrp: 0.551 ± 0.024	0.951PheTyr: 0.951 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	9.706GlyAla: 9.706 ± 0.101	0.853GlyCys: 0.853 ± 0.026	4.734GlyAsp: 4.734 ± 0.073	4.388GlyGlu: 4.388 ± 0.067	3.62GlyPhe: 3.62 ± 0.055	7.262GlyGly: 7.262 ± 0.106	1.933GlyHis: 1.933 ± 0.042	4.3GlyIle: 4.3 ± 0.062	2.899GlyLys: 2.899 ± 0.053	9.301GlyLeu: 9.301 ± 0.084	2.362GlyMet: 2.362 ± 0.038	2.152GlyAsn: 2.152 ± 0.055	3.464GlyPro: 3.464 ± 0.052	3.339GlyGln: 3.339 ± 0.056	5.516GlyArg: 5.516 ± 0.057	4.189GlySer: 4.189 ± 0.061	4.538GlyThr: 4.538 ± 0.061	6.187GlyVal: 6.187 ± 0.076	1.359GlyTrp: 1.359 ± 0.032	2.257GlyTyr: 2.257 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	2.306HisAla: 2.306 ± 0.042	0.257HisCys: 0.257 ± 0.014	1.248HisAsp: 1.248 ± 0.031	1.017HisGlu: 1.017 ± 0.028	0.829HisPhe: 0.829 ± 0.023	1.837HisGly: 1.837 ± 0.034	0.557HisHis: 0.557 ± 0.024	0.978HisIle: 0.978 ± 0.029	0.553HisLys: 0.553 ± 0.019	2.254HisLeu: 2.254 ± 0.043	0.574HisMet: 0.574 ± 0.021	0.461HisAsn: 0.461 ± 0.019	1.387HisPro: 1.387 ± 0.033	0.683HisGln: 0.683 ± 0.021	1.471HisArg: 1.471 ± 0.037	0.994HisSer: 0.994 ± 0.026	0.846HisThr: 0.846 ± 0.027	1.492HisVal: 1.492 ± 0.032	0.379HisTrp: 0.379 ± 0.019	0.542HisTyr: 0.542 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	6.734IleAla: 6.734 ± 0.078	0.648IleCys: 0.648 ± 0.02	3.355IleAsp: 3.355 ± 0.043	3.492IleGlu: 3.492 ± 0.052	1.804IlePhe: 1.804 ± 0.036	4.707IleGly: 4.707 ± 0.066	0.91IleHis: 0.91 ± 0.026	2.017IleIle: 2.017 ± 0.047	1.499IleLys: 1.499 ± 0.033	4.876IleLeu: 4.876 ± 0.069	1.052IleMet: 1.052 ± 0.029	1.397IleAsn: 1.397 ± 0.034	2.248IlePro: 2.248 ± 0.035	1.333IleGln: 1.333 ± 0.03	3.171IleArg: 3.171 ± 0.041	3.129IleSer: 3.129 ± 0.045	2.857IleThr: 2.857 ± 0.045	3.568IleVal: 3.568 ± 0.055	0.771IleTrp: 0.771 ± 0.024	1.216IleTyr: 1.216 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	3.768LysAla: 3.768 ± 0.059	0.158LysCys: 0.158 ± 0.01	1.822LysAsp: 1.822 ± 0.045	1.537LysGlu: 1.537 ± 0.04	0.95LysPhe: 0.95 ± 0.027	2.672LysGly: 2.672 ± 0.046	0.663LysHis: 0.663 ± 0.022	1.712LysIle: 1.712 ± 0.037	1.229LysLys: 1.229 ± 0.038	2.923LysLeu: 2.923 ± 0.053	0.885LysMet: 0.885 ± 0.024	0.823LysAsn: 0.823 ± 0.023	1.779LysPro: 1.779 ± 0.043	0.945LysGln: 0.945 ± 0.025	2.168LysArg: 2.168 ± 0.038	1.954LysSer: 1.954 ± 0.042	2.062LysThr: 2.062 ± 0.041	2.226LysVal: 2.226 ± 0.043	0.346LysTrp: 0.346 ± 0.017	0.643LysTyr: 0.643 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	13.03LeuAla: 13.03 ± 0.12	1.092LeuCys: 1.092 ± 0.025	6.139LeuAsp: 6.139 ± 0.073	5.507LeuGlu: 5.507 ± 0.061	3.662LeuPhe: 3.662 ± 0.055	8.391LeuGly: 8.391 ± 0.081	1.999LeuHis: 1.999 ± 0.045	5.076LeuIle: 5.076 ± 0.072	3.359LeuLys: 3.359 ± 0.054	9.435LeuLeu: 9.435 ± 0.121	2.755LeuMet: 2.755 ± 0.038	2.869LeuAsn: 2.869 ± 0.041	5.676LeuPro: 5.676 ± 0.075	3.259LeuGln: 3.259 ± 0.053	7.416LeuArg: 7.416 ± 0.09	6.906LeuSer: 6.906 ± 0.073	6.194LeuThr: 6.194 ± 0.072	7.085LeuVal: 7.085 ± 0.078	1.273LeuTrp: 1.273 ± 0.031	1.943LeuTyr: 1.943 ± 0.037	0.0LeuXaa: 0.0 ± 0.0
Met	3.366MetAla: 3.366 ± 0.048	0.186MetCys: 0.186 ± 0.012	1.425MetAsp: 1.425 ± 0.033	1.346MetGlu: 1.346 ± 0.034	0.816MetPhe: 0.816 ± 0.025	2.134MetGly: 2.134 ± 0.038	0.445MetHis: 0.445 ± 0.02	1.553MetIle: 1.553 ± 0.031	1.047MetLys: 1.047 ± 0.031	2.618MetLeu: 2.618 ± 0.046	0.8MetMet: 0.8 ± 0.026	0.791MetAsn: 0.791 ± 0.023	1.417MetPro: 1.417 ± 0.033	1.034MetGln: 1.034 ± 0.028	1.883MetArg: 1.883 ± 0.04	1.831MetSer: 1.831 ± 0.036	2.162MetThr: 2.162 ± 0.036	1.887MetVal: 1.887 ± 0.034	0.224MetTrp: 0.224 ± 0.012	0.331MetTyr: 0.331 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.141AsnAla: 3.141 ± 0.051	0.259AsnCys: 0.259 ± 0.014	1.564AsnAsp: 1.564 ± 0.04	1.185AsnGlu: 1.185 ± 0.028	0.971AsnPhe: 0.971 ± 0.027	2.374AsnGly: 2.374 ± 0.044	0.513AsnHis: 0.513 ± 0.019	1.36AsnIle: 1.36 ± 0.033	0.736AsnLys: 0.736 ± 0.024	2.613AsnLeu: 2.613 ± 0.043	0.724AsnMet: 0.724 ± 0.024	0.693AsnAsn: 0.693 ± 0.023	1.756AsnPro: 1.756 ± 0.039	0.783AsnGln: 0.783 ± 0.024	1.822AsnArg: 1.822 ± 0.037	1.29AsnSer: 1.29 ± 0.029	1.374AsnThr: 1.374 ± 0.031	1.766AsnVal: 1.766 ± 0.037	0.441AsnTrp: 0.441 ± 0.018	0.65AsnTyr: 0.65 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	5.443ProAla: 5.443 ± 0.071	0.385ProCys: 0.385 ± 0.017	3.774ProAsp: 3.774 ± 0.056	4.015ProGlu: 4.015 ± 0.048	1.966ProPhe: 1.966 ± 0.043	4.217ProGly: 4.217 ± 0.06	1.034ProHis: 1.034 ± 0.026	2.176ProIle: 2.176 ± 0.043	1.655ProLys: 1.655 ± 0.033	4.663ProLeu: 4.663 ± 0.069	1.315ProMet: 1.315 ± 0.032	1.303ProAsn: 1.303 ± 0.029	2.254ProPro: 2.254 ± 0.056	1.91ProGln: 1.91 ± 0.034	2.748ProArg: 2.748 ± 0.053	2.592ProSer: 2.592 ± 0.043	2.583ProThr: 2.583 ± 0.047	4.133ProVal: 4.133 ± 0.061	0.64ProTrp: 0.64 ± 0.024	1.11ProTyr: 1.11 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	4.434GlnAla: 4.434 ± 0.059	0.22GlnCys: 0.22 ± 0.012	2.074GlnAsp: 2.074 ± 0.041	1.829GlnGlu: 1.829 ± 0.033	1.185GlnPhe: 1.185 ± 0.031	2.734GlnGly: 2.734 ± 0.04	0.674GlnHis: 0.674 ± 0.023	2.21GlnIle: 2.21 ± 0.04	1.188GlnLys: 1.188 ± 0.032	3.228GlnLeu: 3.228 ± 0.051	1.152GlnMet: 1.152 ± 0.029	0.948GlnAsn: 0.948 ± 0.025	1.708GlnPro: 1.708 ± 0.038	1.312GlnGln: 1.312 ± 0.033	2.42GlnArg: 2.42 ± 0.039	2.125GlnSer: 2.125 ± 0.039	2.048GlnThr: 2.048 ± 0.037	2.569GlnVal: 2.569 ± 0.042	0.4GlnTrp: 0.4 ± 0.016	0.617GlnTyr: 0.617 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	8.16ArgAla: 8.16 ± 0.084	0.527ArgCys: 0.527 ± 0.022	4.285ArgAsp: 4.285 ± 0.065	3.535ArgGlu: 3.535 ± 0.062	2.684ArgPhe: 2.684 ± 0.043	4.449ArgGly: 4.449 ± 0.057	1.607ArgHis: 1.607 ± 0.035	3.722ArgIle: 3.722 ± 0.053	2.262ArgLys: 2.262 ± 0.041	7.454ArgLeu: 7.454 ± 0.092	1.89ArgMet: 1.89 ± 0.041	1.807ArgAsn: 1.807 ± 0.041	3.292ArgPro: 3.292 ± 0.047	2.609ArgGln: 2.609 ± 0.044	4.95ArgArg: 4.95 ± 0.065	3.554ArgSer: 3.554 ± 0.058	3.031ArgThr: 3.031 ± 0.046	4.538ArgVal: 4.538 ± 0.055	0.869ArgTrp: 0.869 ± 0.027	1.543ArgTyr: 1.543 ± 0.035	0.0ArgXaa: 0.0 ± 0.0
Ser	6.17SerAla: 6.17 ± 0.072	0.499SerCys: 0.499 ± 0.021	3.54SerAsp: 3.54 ± 0.05	3.037SerGlu: 3.037 ± 0.042	2.29SerPhe: 2.29 ± 0.041	5.331SerGly: 5.331 ± 0.069	1.181SerHis: 1.181 ± 0.028	2.574SerIle: 2.574 ± 0.046	1.527SerLys: 1.527 ± 0.031	5.377SerLeu: 5.377 ± 0.061	1.387SerMet: 1.387 ± 0.03	1.422SerAsn: 1.422 ± 0.037	2.566SerPro: 2.566 ± 0.045	1.815SerGln: 1.815 ± 0.04	3.331SerArg: 3.331 ± 0.051	2.78SerSer: 2.78 ± 0.057	2.638SerThr: 2.638 ± 0.042	3.959SerVal: 3.959 ± 0.058	0.766SerTrp: 0.766 ± 0.023	1.388SerTyr: 1.388 ± 0.03	0.0SerXaa: 0.0 ± 0.0
Thr	6.31ThrAla: 6.31 ± 0.072	0.521ThrCys: 0.521 ± 0.021	3.133ThrAsp: 3.133 ± 0.046	3.235ThrGlu: 3.235 ± 0.049	1.997ThrPhe: 1.997 ± 0.043	5.421ThrGly: 5.421 ± 0.073	1.081ThrHis: 1.081 ± 0.029	2.648ThrIle: 2.648 ± 0.048	1.459ThrLys: 1.459 ± 0.032	6.274ThrLeu: 6.274 ± 0.073	1.315ThrMet: 1.315 ± 0.033	1.292ThrAsn: 1.292 ± 0.029	3.404ThrPro: 3.404 ± 0.054	1.808ThrGln: 1.808 ± 0.038	3.506ThrArg: 3.506 ± 0.057	2.942ThrSer: 2.942 ± 0.045	2.914ThrThr: 2.914 ± 0.053	4.166ThrVal: 4.166 ± 0.058	0.675ThrTrp: 0.675 ± 0.024	1.363ThrTyr: 1.363 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	8.836ValAla: 8.836 ± 0.094	0.627ValCys: 0.627 ± 0.021	4.036ValAsp: 4.036 ± 0.059	4.515ValGlu: 4.515 ± 0.058	2.92ValPhe: 2.92 ± 0.045	5.31ValGly: 5.31 ± 0.074	1.292ValHis: 1.292 ± 0.033	4.094ValIle: 4.094 ± 0.058	2.134ValLys: 2.134 ± 0.045	7.635ValLeu: 7.635 ± 0.088	2.069ValMet: 2.069 ± 0.036	1.973ValAsn: 1.973 ± 0.037	3.484ValPro: 3.484 ± 0.054	2.217ValGln: 2.217 ± 0.041	4.07ValArg: 4.07 ± 0.056	4.278ValSer: 4.278 ± 0.058	4.626ValThr: 4.626 ± 0.057	5.678ValVal: 5.678 ± 0.076	0.892ValTrp: 0.892 ± 0.028	1.443ValTyr: 1.443 ± 0.029	0.0ValXaa: 0.0 ± 0.0
Trp	1.295TrpAla: 1.295 ± 0.032	0.147TrpCys: 0.147 ± 0.012	0.731TrpAsp: 0.731 ± 0.022	0.62TrpGlu: 0.62 ± 0.022	0.546TrpPhe: 0.546 ± 0.023	0.954TrpGly: 0.954 ± 0.029	0.34TrpHis: 0.34 ± 0.017	0.688TrpIle: 0.688 ± 0.023	0.438TrpLys: 0.438 ± 0.017	1.557TrpLeu: 1.557 ± 0.038	0.397TrpMet: 0.397 ± 0.018	0.414TrpAsn: 0.414 ± 0.017	0.67TrpPro: 0.67 ± 0.02	0.636TrpGln: 0.636 ± 0.022	1.055TrpArg: 1.055 ± 0.028	0.827TrpSer: 0.827 ± 0.028	0.752TrpThr: 0.752 ± 0.026	0.901TrpVal: 0.901 ± 0.024	0.213TrpTrp: 0.213 ± 0.012	0.258TrpTyr: 0.258 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.452TyrAla: 2.452 ± 0.044	0.239TyrCys: 0.239 ± 0.014	1.604TyrAsp: 1.604 ± 0.037	1.231TyrGlu: 1.231 ± 0.034	0.902TyrPhe: 0.902 ± 0.025	2.049TyrGly: 2.049 ± 0.043	0.52TyrHis: 0.52 ± 0.017	0.938TyrIle: 0.938 ± 0.025	0.578TyrLys: 0.578 ± 0.019	2.336TyrLeu: 2.336 ± 0.041	0.499TyrMet: 0.499 ± 0.017	0.606TyrAsn: 0.606 ± 0.023	1.092TyrPro: 1.092 ± 0.025	0.771TyrGln: 0.771 ± 0.023	1.548TyrArg: 1.548 ± 0.034	1.164TyrSer: 1.164 ± 0.032	1.115TyrThr: 1.115 ± 0.032	1.566TyrVal: 1.566 ± 0.032	0.338TyrTrp: 0.338 ± 0.016	0.566TyrTyr: 0.566 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4579 proteins (1430001 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---