Amino acid dipepetide frequency for Halalkalicoccus jeotgali (strain DSM 18796 / CECT 7217 / JCM 14584 / KCTC 4019 / B3)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.479AlaAla: 11.479 ± 0.157
0.819AlaCys: 0.819 ± 0.032
7.88AlaAsp: 7.88 ± 0.111
8.503AlaGlu: 8.503 ± 0.11
4.062AlaPhe: 4.062 ± 0.059
9.707AlaGly: 9.707 ± 0.111
1.811AlaHis: 1.811 ± 0.045
5.843AlaIle: 5.843 ± 0.08
1.872AlaLys: 1.872 ± 0.046
10.882AlaLeu: 10.882 ± 0.133
2.157AlaMet: 2.157 ± 0.051
2.343AlaAsn: 2.343 ± 0.046
3.725AlaPro: 3.725 ± 0.067
2.174AlaGln: 2.174 ± 0.052
6.49AlaArg: 6.49 ± 0.087
5.342AlaSer: 5.342 ± 0.083
6.411AlaThr: 6.411 ± 0.083
9.451AlaVal: 9.451 ± 0.128
1.059AlaTrp: 1.059 ± 0.035
2.763AlaTyr: 2.763 ± 0.052
0.0AlaXaa: 0.0 ± 0.0
Cys
0.648CysAla: 0.648 ± 0.03
0.099CysCys: 0.099 ± 0.009
0.515CysAsp: 0.515 ± 0.022
0.782CysGlu: 0.782 ± 0.028
0.223CysPhe: 0.223 ± 0.015
0.906CysGly: 0.906 ± 0.035
0.186CysHis: 0.186 ± 0.015
0.297CysIle: 0.297 ± 0.017
0.125CysLys: 0.125 ± 0.011
0.615CysLeu: 0.615 ± 0.024
0.138CysMet: 0.138 ± 0.014
0.205CysAsn: 0.205 ± 0.014
0.513CysPro: 0.513 ± 0.026
0.166CysGln: 0.166 ± 0.013
0.501CysArg: 0.501 ± 0.025
0.47CysSer: 0.47 ± 0.025
0.442CysThr: 0.442 ± 0.02
0.552CysVal: 0.552 ± 0.023
0.099CysTrp: 0.099 ± 0.009
0.233CysTyr: 0.233 ± 0.015
0.0CysXaa: 0.0 ± 0.0
Asp
7.587AspAla: 7.587 ± 0.105
0.649AspCys: 0.649 ± 0.032
5.631AspAsp: 5.631 ± 0.101
6.997AspGlu: 6.997 ± 0.105
1.845AspPhe: 1.845 ± 0.042
6.899AspGly: 6.899 ± 0.109
1.762AspHis: 1.762 ± 0.047
2.835AspIle: 2.835 ± 0.06
0.883AspLys: 0.883 ± 0.04
7.2AspLeu: 7.2 ± 0.092
1.264AspMet: 1.264 ± 0.032
1.258AspAsn: 1.258 ± 0.04
4.747AspPro: 4.747 ± 0.085
1.547AspGln: 1.547 ± 0.042
6.153AspArg: 6.153 ± 0.092
3.816AspSer: 3.816 ± 0.066
3.787AspThr: 3.787 ± 0.071
6.41AspVal: 6.41 ± 0.083
0.942AspTrp: 0.942 ± 0.031
1.717AspTyr: 1.717 ± 0.041
0.0AspXaa: 0.0 ± 0.0
Glu
9.13GluAla: 9.13 ± 0.116
0.666GluCys: 0.666 ± 0.029
5.886GluAsp: 5.886 ± 0.08
8.199GluGlu: 8.199 ± 0.118
3.264GluPhe: 3.264 ± 0.057
6.921GluGly: 6.921 ± 0.092
2.044GluHis: 2.044 ± 0.045
4.664GluIle: 4.664 ± 0.072
2.011GluLys: 2.011 ± 0.048
7.645GluLeu: 7.645 ± 0.095
1.866GluMet: 1.866 ± 0.037
2.625GluAsn: 2.625 ± 0.053
3.925GluPro: 3.925 ± 0.064
2.503GluGln: 2.503 ± 0.052
8.604GluArg: 8.604 ± 0.118
5.177GluSer: 5.177 ± 0.069
6.532GluThr: 6.532 ± 0.09
5.733GluVal: 5.733 ± 0.097
1.266GluTrp: 1.266 ± 0.035
3.096GluTyr: 3.096 ± 0.061
0.001GluXaa: 0.001 ± 0.001
Phe
3.68PheAla: 3.68 ± 0.076
0.301PheCys: 0.301 ± 0.017
2.999PheAsp: 2.999 ± 0.055
3.523PheGlu: 3.523 ± 0.061
1.126PhePhe: 1.126 ± 0.035
3.489PheGly: 3.489 ± 0.065
0.636PheHis: 0.636 ± 0.026
1.203PheIle: 1.203 ± 0.041
0.531PheLys: 0.531 ± 0.023
3.024PheLeu: 3.024 ± 0.059
0.576PheMet: 0.576 ± 0.026
0.696PheAsn: 0.696 ± 0.027
1.457PhePro: 1.457 ± 0.037
0.694PheGln: 0.694 ± 0.025
1.788PheArg: 1.788 ± 0.039
1.995PheSer: 1.995 ± 0.044
1.777PheThr: 1.777 ± 0.046
3.325PheVal: 3.325 ± 0.063
0.419PheTrp: 0.419 ± 0.022
0.957PheTyr: 0.957 ± 0.033
0.0PheXaa: 0.0 ± 0.0
Gly
8.501GlyAla: 8.501 ± 0.115
0.762GlyCys: 0.762 ± 0.027
5.537GlyAsp: 5.537 ± 0.086
8.132GlyGlu: 8.132 ± 0.101
3.425GlyPhe: 3.425 ± 0.054
7.486GlyGly: 7.486 ± 0.121
1.702GlyHis: 1.702 ± 0.045
5.05GlyIle: 5.05 ± 0.074
1.974GlyLys: 1.974 ± 0.047
8.063GlyLeu: 8.063 ± 0.121
1.935GlyMet: 1.935 ± 0.046
1.951GlyAsn: 1.951 ± 0.049
3.483GlyPro: 3.483 ± 0.06
1.998GlyGln: 1.998 ± 0.052
5.246GlyArg: 5.246 ± 0.085
5.223GlySer: 5.223 ± 0.069
5.917GlyThr: 5.917 ± 0.078
7.37GlyVal: 7.37 ± 0.086
1.232GlyTrp: 1.232 ± 0.04
2.848GlyTyr: 2.848 ± 0.056
0.0GlyXaa: 0.0 ± 0.0
His
2.051HisAla: 2.051 ± 0.049
0.203HisCys: 0.203 ± 0.013
1.748HisAsp: 1.748 ± 0.046
1.848HisGlu: 1.848 ± 0.042
0.539HisPhe: 0.539 ± 0.024
1.989HisGly: 1.989 ± 0.05
0.564HisHis: 0.564 ± 0.03
0.795HisIle: 0.795 ± 0.026
0.286HisLys: 0.286 ± 0.021
1.774HisLeu: 1.774 ± 0.043
0.349HisMet: 0.349 ± 0.019
0.46HisAsn: 0.46 ± 0.025
1.28HisPro: 1.28 ± 0.034
0.467HisGln: 0.467 ± 0.021
1.328HisArg: 1.328 ± 0.036
0.915HisSer: 0.915 ± 0.033
1.205HisThr: 1.205 ± 0.038
1.683HisVal: 1.683 ± 0.045
0.248HisTrp: 0.248 ± 0.016
0.593HisTyr: 0.593 ± 0.027
0.0HisXaa: 0.0 ± 0.0
Ile
5.697IleAla: 5.697 ± 0.081
0.311IleCys: 0.311 ± 0.017
4.353IleAsp: 4.353 ± 0.07
5.585IleGlu: 5.585 ± 0.075
0.982IlePhe: 0.982 ± 0.036
4.594IleGly: 4.594 ± 0.068
0.991IleHis: 0.991 ± 0.031
1.492IleIle: 1.492 ± 0.046
0.791IleLys: 0.791 ± 0.027
3.105IleLeu: 3.105 ± 0.071
0.61IleMet: 0.61 ± 0.026
1.197IleAsn: 1.197 ± 0.034
2.34IlePro: 2.34 ± 0.049
1.129IleGln: 1.129 ± 0.037
2.775IleArg: 2.775 ± 0.05
2.35IleSer: 2.35 ± 0.053
2.93IleThr: 2.93 ± 0.055
4.074IleVal: 4.074 ± 0.077
0.372IleTrp: 0.372 ± 0.019
1.122IleTyr: 1.122 ± 0.037
0.0IleXaa: 0.0 ± 0.0
Lys
1.776LysAla: 1.776 ± 0.048
0.117LysCys: 0.117 ± 0.012
1.095LysAsp: 1.095 ± 0.046
1.502LysGlu: 1.502 ± 0.043
0.567LysPhe: 0.567 ± 0.025
1.446LysGly: 1.446 ± 0.036
0.503LysHis: 0.503 ± 0.023
0.787LysIle: 0.787 ± 0.033
0.615LysLys: 0.615 ± 0.04
1.581LysLeu: 1.581 ± 0.043
0.36LysMet: 0.36 ± 0.022
0.583LysAsn: 0.583 ± 0.027
0.952LysPro: 0.952 ± 0.029
0.737LysGln: 0.737 ± 0.028
1.858LysArg: 1.858 ± 0.048
1.104LysSer: 1.104 ± 0.032
1.269LysThr: 1.269 ± 0.034
1.128LysVal: 1.128 ± 0.035
0.231LysTrp: 0.231 ± 0.018
0.606LysTyr: 0.606 ± 0.024
0.0LysXaa: 0.0 ± 0.0
Leu
11.486LeuAla: 11.486 ± 0.149
0.668LeuCys: 0.668 ± 0.027
7.083LeuAsp: 7.083 ± 0.098
7.302LeuGlu: 7.302 ± 0.095
3.403LeuPhe: 3.403 ± 0.07
8.05LeuGly: 8.05 ± 0.108
1.468LeuHis: 1.468 ± 0.041
3.804LeuIle: 3.804 ± 0.067
1.52LeuLys: 1.52 ± 0.041
8.96LeuLeu: 8.96 ± 0.133
1.452LeuMet: 1.452 ± 0.038
1.858LeuAsn: 1.858 ± 0.044
4.328LeuPro: 4.328 ± 0.065
1.913LeuGln: 1.913 ± 0.047
5.302LeuArg: 5.302 ± 0.076
6.209LeuSer: 6.209 ± 0.086
5.36LeuThr: 5.36 ± 0.075
8.35LeuVal: 8.35 ± 0.122
0.896LeuTrp: 0.896 ± 0.031
2.357LeuTyr: 2.357 ± 0.056
0.0LeuXaa: 0.0 ± 0.0
Met
2.077MetAla: 2.077 ± 0.05
0.131MetCys: 0.131 ± 0.011
1.316MetAsp: 1.316 ± 0.04
1.252MetGlu: 1.252 ± 0.037
0.57MetPhe: 0.57 ± 0.022
1.703MetGly: 1.703 ± 0.04
0.391MetHis: 0.391 ± 0.019
0.851MetIle: 0.851 ± 0.034
0.51MetLys: 0.51 ± 0.025
1.655MetLeu: 1.655 ± 0.048
0.377MetMet: 0.377 ± 0.022
0.751MetAsn: 0.751 ± 0.026
0.818MetPro: 0.818 ± 0.027
0.458MetGln: 0.458 ± 0.02
1.102MetArg: 1.102 ± 0.033
1.568MetSer: 1.568 ± 0.037
1.412MetThr: 1.412 ± 0.035
1.41MetVal: 1.41 ± 0.038
0.184MetTrp: 0.184 ± 0.013
0.442MetTyr: 0.442 ± 0.022
0.0MetXaa: 0.0 ± 0.0
Asn
2.691AsnAla: 2.691 ± 0.053
0.242AsnCys: 0.242 ± 0.018
1.698AsnAsp: 1.698 ± 0.045
1.925AsnGlu: 1.925 ± 0.051
0.666AsnPhe: 0.666 ± 0.024
2.027AsnGly: 2.027 ± 0.046
0.556AsnHis: 0.556 ± 0.022
0.93AsnIle: 0.93 ± 0.03
0.421AsnLys: 0.421 ± 0.022
1.856AsnLeu: 1.856 ± 0.048
0.421AsnMet: 0.421 ± 0.02
0.575AsnAsn: 0.575 ± 0.029
1.548AsnPro: 1.548 ± 0.037
0.706AsnGln: 0.706 ± 0.027
1.721AsnArg: 1.721 ± 0.039
0.992AsnSer: 0.992 ± 0.039
1.417AsnThr: 1.417 ± 0.039
2.195AsnVal: 2.195 ± 0.047
0.316AsnTrp: 0.316 ± 0.017
0.705AsnTyr: 0.705 ± 0.025
0.0AsnXaa: 0.0 ± 0.0
Pro
4.74ProAla: 4.74 ± 0.086
0.252ProCys: 0.252 ± 0.016
4.445ProAsp: 4.445 ± 0.073
5.38ProGlu: 5.38 ± 0.082
1.606ProPhe: 1.606 ± 0.037
3.786ProGly: 3.786 ± 0.073
0.94ProHis: 0.94 ± 0.026
2.267ProIle: 2.267 ± 0.045
0.87ProLys: 0.87 ± 0.03
3.807ProLeu: 3.807 ± 0.059
0.886ProMet: 0.886 ± 0.028
1.146ProAsn: 1.146 ± 0.034
2.076ProPro: 2.076 ± 0.046
0.954ProGln: 0.954 ± 0.03
2.387ProArg: 2.387 ± 0.049
2.389ProSer: 2.389 ± 0.052
3.111ProThr: 3.111 ± 0.055
4.101ProVal: 4.101 ± 0.069
0.534ProTrp: 0.534 ± 0.025
1.233ProTyr: 1.233 ± 0.036
0.0ProXaa: 0.0 ± 0.0
Gln
2.242GlnAla: 2.242 ± 0.054
0.151GlnCys: 0.151 ± 0.013
1.219GlnAsp: 1.219 ± 0.036
1.666GlnGlu: 1.666 ± 0.043
1.01GlnPhe: 1.01 ± 0.032
1.656GlnGly: 1.656 ± 0.043
0.54GlnHis: 0.54 ± 0.025
1.149GlnIle: 1.149 ± 0.041
0.601GlnLys: 0.601 ± 0.026
2.294GlnLeu: 2.294 ± 0.057
0.555GlnMet: 0.555 ± 0.025
0.702GlnAsn: 0.702 ± 0.025
1.1GlnPro: 1.1 ± 0.037
0.957GlnGln: 0.957 ± 0.036
1.96GlnArg: 1.96 ± 0.046
1.482GlnSer: 1.482 ± 0.044
1.557GlnThr: 1.557 ± 0.041
1.61GlnVal: 1.61 ± 0.04
0.352GlnTrp: 0.352 ± 0.022
0.818GlnTyr: 0.818 ± 0.029
0.0GlnXaa: 0.0 ± 0.0
Arg
6.568ArgAla: 6.568 ± 0.096
0.487ArgCys: 0.487 ± 0.026
4.377ArgAsp: 4.377 ± 0.072
7.901ArgGlu: 7.901 ± 0.115
2.465ArgPhe: 2.465 ± 0.05
4.73ArgGly: 4.73 ± 0.079
1.266ArgHis: 1.266 ± 0.034
3.42ArgIle: 3.42 ± 0.055
1.471ArgLys: 1.471 ± 0.045
6.141ArgLeu: 6.141 ± 0.089
1.526ArgMet: 1.526 ± 0.036
1.588ArgAsn: 1.588 ± 0.042
2.673ArgPro: 2.673 ± 0.05
1.641ArgGln: 1.641 ± 0.046
4.769ArgArg: 4.769 ± 0.086
3.522ArgSer: 3.522 ± 0.069
4.182ArgThr: 4.182 ± 0.078
5.282ArgVal: 5.282 ± 0.082
0.802ArgTrp: 0.802 ± 0.029
2.07ArgTyr: 2.07 ± 0.048
0.0ArgXaa: 0.0 ± 0.0
Ser
5.403SerAla: 5.403 ± 0.075
0.342SerCys: 0.342 ± 0.02
4.014SerAsp: 4.014 ± 0.074
4.808SerGlu: 4.808 ± 0.065
1.847SerPhe: 1.847 ± 0.043
5.49SerGly: 5.49 ± 0.078
1.055SerHis: 1.055 ± 0.034
2.897SerIle: 2.897 ± 0.051
1.213SerLys: 1.213 ± 0.038
4.952SerLeu: 4.952 ± 0.08
1.246SerMet: 1.246 ± 0.036
1.35SerAsn: 1.35 ± 0.044
2.665SerPro: 2.665 ± 0.053
1.445SerGln: 1.445 ± 0.041
3.245SerArg: 3.245 ± 0.066
2.86SerSer: 2.86 ± 0.074
3.389SerThr: 3.389 ± 0.054
4.902SerVal: 4.902 ± 0.071
0.593SerTrp: 0.593 ± 0.023
1.459SerTyr: 1.459 ± 0.04
0.0SerXaa: 0.0 ± 0.0
Thr
6.335ThrAla: 6.335 ± 0.089
0.417ThrCys: 0.417 ± 0.02
5.186ThrAsp: 5.186 ± 0.081
4.911ThrGlu: 4.911 ± 0.066
2.038ThrPhe: 2.038 ± 0.046
5.799ThrGly: 5.799 ± 0.077
1.275ThrHis: 1.275 ± 0.035
3.133ThrIle: 3.133 ± 0.067
1.076ThrLys: 1.076 ± 0.034
5.808ThrLeu: 5.808 ± 0.079
1.132ThrMet: 1.132 ± 0.036
1.479ThrAsn: 1.479 ± 0.035
3.268ThrPro: 3.268 ± 0.054
1.413ThrGln: 1.413 ± 0.04
3.395ThrArg: 3.395 ± 0.051
2.781ThrSer: 2.781 ± 0.056
4.108ThrThr: 4.108 ± 0.066
6.485ThrVal: 6.485 ± 0.079
0.603ThrTrp: 0.603 ± 0.023
1.671ThrTyr: 1.671 ± 0.043
0.001ThrXaa: 0.001 ± 0.001
Val
8.963ValAla: 8.963 ± 0.106
0.739ValCys: 0.739 ± 0.028
5.636ValAsp: 5.636 ± 0.079
8.02ValGlu: 8.02 ± 0.085
3.152ValPhe: 3.152 ± 0.065
7.747ValGly: 7.747 ± 0.109
1.696ValHis: 1.696 ± 0.044
3.898ValIle: 3.898 ± 0.061
1.326ValLys: 1.326 ± 0.033
8.58ValLeu: 8.58 ± 0.121
1.451ValMet: 1.451 ± 0.033
1.805ValAsn: 1.805 ± 0.042
4.229ValPro: 4.229 ± 0.072
1.663ValGln: 1.663 ± 0.044
5.284ValArg: 5.284 ± 0.072
4.982ValSer: 4.982 ± 0.066
5.092ValThr: 5.092 ± 0.08
7.765ValVal: 7.765 ± 0.124
0.825ValTrp: 0.825 ± 0.031
2.113ValTyr: 2.113 ± 0.049
0.0ValXaa: 0.0 ± 0.0
Trp
0.914TrpAla: 0.914 ± 0.028
0.091TrpCys: 0.091 ± 0.009
0.798TrpAsp: 0.798 ± 0.035
0.924TrpGlu: 0.924 ± 0.036
0.511TrpPhe: 0.511 ± 0.023
0.84TrpGly: 0.84 ± 0.033
0.25TrpHis: 0.25 ± 0.014
0.635TrpIle: 0.635 ± 0.024
0.285TrpLys: 0.285 ± 0.016
1.226TrpLeu: 1.226 ± 0.039
0.252TrpMet: 0.252 ± 0.018
0.334TrpAsn: 0.334 ± 0.02
0.451TrpPro: 0.451 ± 0.023
0.328TrpGln: 0.328 ± 0.019
0.838TrpArg: 0.838 ± 0.026
0.628TrpSer: 0.628 ± 0.025
0.776TrpThr: 0.776 ± 0.029
0.845TrpVal: 0.845 ± 0.029
0.2TrpTrp: 0.2 ± 0.016
0.393TrpTyr: 0.393 ± 0.021
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.805TyrAla: 2.805 ± 0.055
0.266TyrCys: 0.266 ± 0.016
2.514TyrAsp: 2.514 ± 0.052
2.594TyrGlu: 2.594 ± 0.056
0.893TyrPhe: 0.893 ± 0.029
2.571TyrGly: 2.571 ± 0.049
0.689TyrHis: 0.689 ± 0.027
0.852TyrIle: 0.852 ± 0.032
0.439TyrLys: 0.439 ± 0.022
2.6TyrLeu: 2.6 ± 0.05
0.426TyrMet: 0.426 ± 0.019
0.704TyrAsn: 0.704 ± 0.027
1.331TyrPro: 1.331 ± 0.038
0.727TyrGln: 0.727 ± 0.028
2.135TyrArg: 2.135 ± 0.05
1.369TyrSer: 1.369 ± 0.036
1.639TyrThr: 1.639 ± 0.042
2.296TyrVal: 2.296 ± 0.051
0.345TyrTrp: 0.345 ± 0.019
0.906TyrTyr: 0.906 ± 0.029
0.001TyrXaa: 0.001 ± 0.001
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.001XaaAsp: 0.001 ± 0.001
0.001XaaGlu: 0.001 ± 0.001
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.001XaaVal: 0.001 ± 0.001
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.005XaaXaa: 0.005 ± 0.006
Statistics based on 3779 proteins (1011784 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski