Actinomyces denticolens

Taxonomy: cellular organisms; Bacteria; Terrabacteria group; Actinobacteria; Actinomycetia; Actinomycetales; Actinomycetaceae; Actinomyces

Average proteome isoelectric point is 6.17

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2279 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A1M5ZXV7|A0A1M5ZXV7_9ACTO Adenylate cyclase OS=Actinomyces denticolens OX=52767 GN=SAMN05216246_10137 PE=3 SV=1
MM1 pKa = 7.15STGPYY6 pKa = 9.86DD7 pKa = 4.51PNIQYY12 pKa = 10.49DD13 pKa = 3.98AAPASPTGPSTPMGAPAGGPPAYY36 pKa = 10.31GMGGQYY42 pKa = 8.15PAPGQAPPTPPSTKK56 pKa = 9.67RR57 pKa = 11.84KK58 pKa = 10.21GIIALIAGLAVLSLLVTGGILAAYY82 pKa = 8.62KK83 pKa = 10.67DD84 pKa = 4.2SGDD87 pKa = 4.14SSDD90 pKa = 3.7SAAGGSSASTGADD103 pKa = 2.89SSGGKK108 pKa = 10.24LGDD111 pKa = 3.81KK112 pKa = 10.29ASKK115 pKa = 10.35AAVGDD120 pKa = 4.74CIDD123 pKa = 4.22SLTSPSATIVACDD136 pKa = 3.52DD137 pKa = 3.42AGAAFKK143 pKa = 10.84VVAASTTKK151 pKa = 9.77EE152 pKa = 3.85ACATTPGGDD161 pKa = 3.49YY162 pKa = 10.75FDD164 pKa = 6.72DD165 pKa = 3.84STCYY169 pKa = 10.72NDD171 pKa = 4.56LSTGIPVEE179 pKa = 4.08EE180 pKa = 4.48SVNDD184 pKa = 4.01AKK186 pKa = 11.28AGDD189 pKa = 4.47CVAADD194 pKa = 4.66DD195 pKa = 4.7TDD197 pKa = 3.61SSNPSVRR204 pKa = 11.84KK205 pKa = 8.03TDD207 pKa = 3.42CSTTGALRR215 pKa = 11.84VEE217 pKa = 4.55GTLPGVSGVPTIAIPTIDD235 pKa = 3.65VSNPGPAPTLEE246 pKa = 4.24DD247 pKa = 3.29VRR249 pKa = 11.84TQYY252 pKa = 10.96IIDD255 pKa = 3.5QCVAAGSTGTTAVYY269 pKa = 10.06SWNLGGTSLTGFQTDD284 pKa = 3.68TPSSYY289 pKa = 11.33DD290 pKa = 3.26AVLCLSQGAA299 pKa = 3.79

Molecular weight: 29.33 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A1M6EM70|A0A1M6EM70_9ACTO Cell division protein CrgA OS=Actinomyces denticolens OX=52767 GN=crgA PE=3 SV=1
MM1 pKa = 7.69SKK3 pKa = 9.0RR4 pKa = 11.84TFQPNNRR11 pKa = 11.84RR12 pKa = 11.84RR13 pKa = 11.84AKK15 pKa = 9.4VHH17 pKa = 5.52GFRR20 pKa = 11.84KK21 pKa = 9.95RR22 pKa = 11.84MSTRR26 pKa = 11.84AGRR29 pKa = 11.84AVLASRR35 pKa = 11.84RR36 pKa = 11.84RR37 pKa = 11.84KK38 pKa = 9.61GRR40 pKa = 11.84ARR42 pKa = 11.84LAAA45 pKa = 4.44

Molecular weight: 5.27 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2279

0

2279

815642

27

3198

357.9

37.87

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

14.736 ± 0.086

0.729 ± 0.014

5.931 ± 0.047

5.616 ± 0.059

2.309 ± 0.027

9.583 ± 0.049

1.954 ± 0.02

4.338 ± 0.037

1.75 ± 0.038

9.985 ± 0.067

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.021 ± 0.022

1.686 ± 0.029

6.074 ± 0.043

2.496 ± 0.023

7.734 ± 0.054

5.992 ± 0.043

5.87 ± 0.042

7.875 ± 0.046

1.471 ± 0.026

1.85 ± 0.026
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski