Coronavirus AcCoV-JC34

Taxonomy: Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae; Alphacoronavirus; Luchacovirus; unclassified Luchacovirus

Average proteome isoelectric point is 6.43

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 9 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A1X9JJV5|A0A1X9JJV5_9ALPC Membrane protein OS=Coronavirus AcCoV-JC34 OX=1964806 GN=M PE=3 SV=1
MM1 pKa = 7.47ILVFLVLIASVGAITDD17 pKa = 3.79SKK19 pKa = 10.9SNCSFSFSSLLVDD32 pKa = 3.7GTVSFDD38 pKa = 3.17TVHH41 pKa = 6.85RR42 pKa = 11.84VTFANCFFNWEE53 pKa = 4.1DD54 pKa = 3.3WFGCTSDD61 pKa = 4.53CDD63 pKa = 3.91LMAPLLSAFMPANTSEE79 pKa = 4.05MFQVCNGISVPDD91 pKa = 4.12FDD93 pKa = 4.64NCVSGFVMRR102 pKa = 11.84YY103 pKa = 7.65GALYY107 pKa = 10.62VPDD110 pKa = 4.39DD111 pKa = 3.65THH113 pKa = 7.98VKK115 pKa = 9.8YY116 pKa = 10.94VPEE119 pKa = 4.16KK120 pKa = 10.69NEE122 pKa = 4.2CFGQLKK128 pKa = 10.05FMNNVIWFITSHH140 pKa = 6.22LTNEE144 pKa = 4.31ICCSNRR150 pKa = 11.84IAANPFIPVIEE161 pKa = 4.23NNNFNN166 pKa = 3.92

Molecular weight: 18.58 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A1X9JPE2|A0A1X9JPE2_9ALPC Growth factor-like peptide (Fragment) OS=Coronavirus AcCoV-JC34 OX=1964806 PE=3 SV=1
MM1 pKa = 7.57IGGLFSVGFEE11 pKa = 4.7QFIQHH16 pKa = 6.58ANVTTGGALTALAAQPLINYY36 pKa = 6.66GTAVFSVYY44 pKa = 11.03SCFFLSFFALYY55 pKa = 10.1SVKK58 pKa = 10.24SDD60 pKa = 3.5RR61 pKa = 11.84ANCLLLFLRR70 pKa = 11.84LLTLFVAVPILFCTGYY86 pKa = 10.78YY87 pKa = 9.5IDD89 pKa = 5.02GSLTILILLSRR100 pKa = 11.84FCYY103 pKa = 10.45LIYY106 pKa = 10.4YY107 pKa = 7.52CVRR110 pKa = 11.84FKK112 pKa = 10.75RR113 pKa = 11.84LHH115 pKa = 6.25FILYY119 pKa = 7.5NTSTLLFAQGRR130 pKa = 11.84CVPYY134 pKa = 10.92VKK136 pKa = 10.43LHH138 pKa = 5.3YY139 pKa = 9.26FANYY143 pKa = 8.33AALYY147 pKa = 9.7GGAGHH152 pKa = 7.61LMLGRR157 pKa = 11.84KK158 pKa = 8.88VINFTEE164 pKa = 3.89ARR166 pKa = 11.84NVVLAVRR173 pKa = 11.84GRR175 pKa = 11.84LQEE178 pKa = 4.37DD179 pKa = 3.76LLLARR184 pKa = 11.84VVEE187 pKa = 4.3LANGEE192 pKa = 4.46CIYY195 pKa = 10.71IFTKK199 pKa = 10.33EE200 pKa = 4.04PAVSVYY206 pKa = 10.68NFSFQPLNN214 pKa = 3.43

Molecular weight: 24.08 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

9

0

9

8971

78

3974

996.8

111.42

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.755 ± 0.493

3.779 ± 0.292

5.462 ± 0.336

3.712 ± 0.132

6.153 ± 0.276

6.465 ± 0.247

1.995 ± 0.188

4.704 ± 0.417

5.105 ± 0.625

8.84 ± 0.403

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.973 ± 0.247

6.12 ± 0.399

3.467 ± 0.396

2.965 ± 0.453

3.478 ± 0.232

6.978 ± 0.348

5.964 ± 0.286

9.676 ± 0.514

1.349 ± 0.144

5.061 ± 0.39
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski