Amino acid dipepetide frequency for Pochonia chlamydosporia 170

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.068AlaAla: 9.068 ± 0.064
1.203AlaCys: 1.203 ± 0.016
4.224AlaAsp: 4.224 ± 0.024
4.9AlaGlu: 4.9 ± 0.044
3.183AlaPhe: 3.183 ± 0.023
5.76AlaGly: 5.76 ± 0.037
1.726AlaHis: 1.726 ± 0.016
4.463AlaIle: 4.463 ± 0.028
4.317AlaLys: 4.317 ± 0.033
7.623AlaLeu: 7.623 ± 0.042
2.093AlaMet: 2.093 ± 0.016
3.087AlaAsn: 3.087 ± 0.024
4.281AlaPro: 4.281 ± 0.036
3.275AlaGln: 3.275 ± 0.026
4.674AlaArg: 4.674 ± 0.029
7.085AlaSer: 7.085 ± 0.041
5.312AlaThr: 5.312 ± 0.031
5.526AlaVal: 5.526 ± 0.03
1.241AlaTrp: 1.241 ± 0.014
2.161AlaTyr: 2.161 ± 0.022
0.0AlaXaa: 0.0 ± 0.0
Cys
1.051CysAla: 1.051 ± 0.013
0.31CysCys: 0.31 ± 0.009
0.746CysAsp: 0.746 ± 0.011
0.644CysGlu: 0.644 ± 0.011
0.601CysPhe: 0.601 ± 0.01
1.049CysGly: 1.049 ± 0.014
0.39CysHis: 0.39 ± 0.008
0.781CysIle: 0.781 ± 0.011
0.613CysLys: 0.613 ± 0.01
1.393CysLeu: 1.393 ± 0.017
0.313CysMet: 0.313 ± 0.007
0.527CysAsn: 0.527 ± 0.009
0.732CysPro: 0.732 ± 0.012
0.553CysGln: 0.553 ± 0.01
0.902CysArg: 0.902 ± 0.014
1.048CysSer: 1.048 ± 0.014
0.785CysThr: 0.785 ± 0.011
0.883CysVal: 0.883 ± 0.013
0.24CysTrp: 0.24 ± 0.007
0.392CysTyr: 0.392 ± 0.008
0.0CysXaa: 0.0 ± 0.0
Asp
4.773AspAla: 4.773 ± 0.028
0.707AspCys: 0.707 ± 0.011
4.338AspAsp: 4.338 ± 0.036
4.436AspGlu: 4.436 ± 0.03
2.188AspPhe: 2.188 ± 0.021
4.33AspGly: 4.33 ± 0.029
1.27AspHis: 1.27 ± 0.016
3.156AspIle: 3.156 ± 0.023
2.712AspLys: 2.712 ± 0.028
4.875AspLeu: 4.875 ± 0.025
1.395AspMet: 1.395 ± 0.014
2.063AspAsn: 2.063 ± 0.02
2.991AspPro: 2.991 ± 0.026
1.922AspGln: 1.922 ± 0.016
2.998AspArg: 2.998 ± 0.03
4.071AspSer: 4.071 ± 0.028
3.059AspThr: 3.059 ± 0.022
3.874AspVal: 3.874 ± 0.027
0.924AspTrp: 0.924 ± 0.011
1.543AspTyr: 1.543 ± 0.014
0.0AspXaa: 0.0 ± 0.0
Glu
5.236GluAla: 5.236 ± 0.049
0.675GluCys: 0.675 ± 0.012
3.954GluAsp: 3.954 ± 0.03
4.72GluGlu: 4.72 ± 0.05
1.965GluPhe: 1.965 ± 0.019
3.348GluGly: 3.348 ± 0.025
1.356GluHis: 1.356 ± 0.014
2.797GluIle: 2.797 ± 0.023
3.434GluLys: 3.434 ± 0.028
5.078GluLeu: 5.078 ± 0.03
1.464GluMet: 1.464 ± 0.015
2.185GluAsn: 2.185 ± 0.02
2.691GluPro: 2.691 ± 0.032
2.426GluGln: 2.426 ± 0.022
3.68GluArg: 3.68 ± 0.036
4.17GluSer: 4.17 ± 0.03
3.366GluThr: 3.366 ± 0.026
3.386GluVal: 3.386 ± 0.026
0.883GluTrp: 0.883 ± 0.011
1.659GluTyr: 1.659 ± 0.018
0.0GluXaa: 0.0 ± 0.0
Phe
3.063PheAla: 3.063 ± 0.023
0.624PheCys: 0.624 ± 0.01
2.332PheAsp: 2.332 ± 0.02
2.095PheGlu: 2.095 ± 0.019
1.628PhePhe: 1.628 ± 0.018
2.906PheGly: 2.906 ± 0.026
0.925PheHis: 0.925 ± 0.014
1.869PheIle: 1.869 ± 0.017
1.594PheLys: 1.594 ± 0.016
3.437PheLeu: 3.437 ± 0.025
0.827PheMet: 0.827 ± 0.011
1.499PheAsn: 1.499 ± 0.015
1.889PhePro: 1.889 ± 0.018
1.414PheGln: 1.414 ± 0.016
1.955PheArg: 1.955 ± 0.018
2.904PheSer: 2.904 ± 0.023
2.19PheThr: 2.19 ± 0.02
2.455PheVal: 2.455 ± 0.023
0.687PheTrp: 0.687 ± 0.011
1.087PheTyr: 1.087 ± 0.012
0.0PheXaa: 0.0 ± 0.0
Gly
5.236GlyAla: 5.236 ± 0.032
0.987GlyCys: 0.987 ± 0.013
3.731GlyAsp: 3.731 ± 0.028
3.514GlyGlu: 3.514 ± 0.029
2.753GlyPhe: 2.753 ± 0.023
5.68GlyGly: 5.68 ± 0.058
1.848GlyHis: 1.848 ± 0.022
3.69GlyIle: 3.69 ± 0.029
3.636GlyLys: 3.636 ± 0.025
6.104GlyLeu: 6.104 ± 0.038
1.683GlyMet: 1.683 ± 0.016
2.767GlyAsn: 2.767 ± 0.029
3.253GlyPro: 3.253 ± 0.028
2.712GlyGln: 2.712 ± 0.023
4.183GlyArg: 4.183 ± 0.033
5.751GlySer: 5.751 ± 0.036
4.002GlyThr: 4.002 ± 0.031
4.405GlyVal: 4.405 ± 0.029
1.235GlyTrp: 1.235 ± 0.017
2.143GlyTyr: 2.143 ± 0.019
0.0GlyXaa: 0.0 ± 0.0
His
1.794HisAla: 1.794 ± 0.018
0.389HisCys: 0.389 ± 0.008
1.42HisAsp: 1.42 ± 0.017
1.343HisGlu: 1.343 ± 0.014
0.948HisPhe: 0.948 ± 0.012
1.883HisGly: 1.883 ± 0.02
0.899HisHis: 0.899 ± 0.019
1.293HisIle: 1.293 ± 0.013
1.024HisLys: 1.024 ± 0.013
2.258HisLeu: 2.258 ± 0.019
0.535HisMet: 0.535 ± 0.01
0.909HisAsn: 0.909 ± 0.013
1.56HisPro: 1.56 ± 0.017
1.061HisGln: 1.061 ± 0.014
1.56HisArg: 1.56 ± 0.018
1.829HisSer: 1.829 ± 0.02
1.263HisThr: 1.263 ± 0.015
1.508HisVal: 1.508 ± 0.016
0.373HisTrp: 0.373 ± 0.007
0.676HisTyr: 0.676 ± 0.011
0.0HisXaa: 0.0 ± 0.0
Ile
4.27IleAla: 4.27 ± 0.027
0.847IleCys: 0.847 ± 0.012
2.879IleAsp: 2.879 ± 0.019
2.712IleGlu: 2.712 ± 0.022
2.009IlePhe: 2.009 ± 0.022
3.289IleGly: 3.289 ± 0.025
1.245IleHis: 1.245 ± 0.013
2.574IleIle: 2.574 ± 0.024
2.228IleLys: 2.228 ± 0.02
4.64IleLeu: 4.64 ± 0.03
1.074IleMet: 1.074 ± 0.012
1.88IleAsn: 1.88 ± 0.016
2.934IlePro: 2.934 ± 0.023
2.0IleGln: 2.0 ± 0.021
2.91IleArg: 2.91 ± 0.025
3.874IleSer: 3.874 ± 0.023
2.901IleThr: 2.901 ± 0.025
3.222IleVal: 3.222 ± 0.024
0.81IleTrp: 0.81 ± 0.012
1.38IleTyr: 1.38 ± 0.016
0.0IleXaa: 0.0 ± 0.0
Lys
4.325LysAla: 4.325 ± 0.03
0.586LysCys: 0.586 ± 0.009
2.986LysAsp: 2.986 ± 0.027
3.145LysGlu: 3.145 ± 0.027
1.567LysPhe: 1.567 ± 0.018
3.084LysGly: 3.084 ± 0.029
1.2LysHis: 1.2 ± 0.016
2.249LysIle: 2.249 ± 0.02
3.217LysLys: 3.217 ± 0.037
4.361LysLeu: 4.361 ± 0.028
1.09LysMet: 1.09 ± 0.014
1.8LysAsn: 1.8 ± 0.018
2.752LysPro: 2.752 ± 0.027
1.928LysGln: 1.928 ± 0.019
3.363LysArg: 3.363 ± 0.027
3.669LysSer: 3.669 ± 0.027
2.955LysThr: 2.955 ± 0.022
2.879LysVal: 2.879 ± 0.025
0.754LysTrp: 0.754 ± 0.011
1.455LysTyr: 1.455 ± 0.015
0.0LysXaa: 0.0 ± 0.0
Leu
7.896LeuAla: 7.896 ± 0.04
1.36LeuCys: 1.36 ± 0.016
5.258LeuAsp: 5.258 ± 0.032
5.22LeuGlu: 5.22 ± 0.036
3.314LeuPhe: 3.314 ± 0.028
6.035LeuGly: 6.035 ± 0.04
2.298LeuHis: 2.298 ± 0.019
3.962LeuIle: 3.962 ± 0.032
4.143LeuLys: 4.143 ± 0.028
8.451LeuLeu: 8.451 ± 0.052
1.842LeuMet: 1.842 ± 0.019
3.153LeuAsn: 3.153 ± 0.023
5.329LeuPro: 5.329 ± 0.033
3.926LeuGln: 3.926 ± 0.033
5.773LeuArg: 5.773 ± 0.035
7.249LeuSer: 7.249 ± 0.039
4.797LeuThr: 4.797 ± 0.029
5.564LeuVal: 5.564 ± 0.03
1.287LeuTrp: 1.287 ± 0.014
2.356LeuTyr: 2.356 ± 0.02
0.0LeuXaa: 0.0 ± 0.0
Met
2.378MetAla: 2.378 ± 0.02
0.272MetCys: 0.272 ± 0.006
1.338MetAsp: 1.338 ± 0.014
1.32MetGlu: 1.32 ± 0.014
0.776MetPhe: 0.776 ± 0.011
1.545MetGly: 1.545 ± 0.016
0.503MetHis: 0.503 ± 0.01
1.004MetIle: 1.004 ± 0.012
1.076MetLys: 1.076 ± 0.013
1.938MetLeu: 1.938 ± 0.018
0.614MetMet: 0.614 ± 0.011
0.853MetAsn: 0.853 ± 0.012
1.342MetPro: 1.342 ± 0.013
0.89MetGln: 0.89 ± 0.013
1.333MetArg: 1.333 ± 0.013
1.927MetSer: 1.927 ± 0.017
1.366MetThr: 1.366 ± 0.014
1.406MetVal: 1.406 ± 0.016
0.289MetTrp: 0.289 ± 0.007
0.579MetTyr: 0.579 ± 0.009
0.0MetXaa: 0.0 ± 0.0
Asn
3.163AsnAla: 3.163 ± 0.026
0.538AsnCys: 0.538 ± 0.009
2.057AsnAsp: 2.057 ± 0.019
2.013AsnGlu: 2.013 ± 0.017
1.42AsnPhe: 1.42 ± 0.016
3.196AsnGly: 3.196 ± 0.034
0.918AsnHis: 0.918 ± 0.012
2.12AsnIle: 2.12 ± 0.017
1.727AsnLys: 1.727 ± 0.017
3.316AsnLeu: 3.316 ± 0.023
0.921AsnMet: 0.921 ± 0.011
1.587AsnAsn: 1.587 ± 0.021
2.333AsnPro: 2.333 ± 0.022
1.382AsnGln: 1.382 ± 0.016
2.045AsnArg: 2.045 ± 0.019
2.849AsnSer: 2.849 ± 0.022
2.248AsnThr: 2.248 ± 0.02
2.407AsnVal: 2.407 ± 0.019
0.628AsnTrp: 0.628 ± 0.011
1.046AsnTyr: 1.046 ± 0.014
0.0AsnXaa: 0.0 ± 0.0
Pro
4.75ProAla: 4.75 ± 0.036
0.638ProCys: 0.638 ± 0.012
3.166ProAsp: 3.166 ± 0.022
3.495ProGlu: 3.495 ± 0.03
2.006ProPhe: 2.006 ± 0.016
3.92ProGly: 3.92 ± 0.028
1.268ProHis: 1.268 ± 0.015
2.451ProIle: 2.451 ± 0.019
2.638ProLys: 2.638 ± 0.023
4.535ProLeu: 4.535 ± 0.028
1.104ProMet: 1.104 ± 0.014
2.223ProAsn: 2.223 ± 0.022
4.596ProPro: 4.596 ± 0.052
2.374ProGln: 2.374 ± 0.026
3.242ProArg: 3.242 ± 0.027
5.503ProSer: 5.503 ± 0.04
3.74ProThr: 3.74 ± 0.032
3.506ProVal: 3.506 ± 0.027
0.781ProTrp: 0.781 ± 0.013
1.4ProTyr: 1.4 ± 0.016
0.0ProXaa: 0.0 ± 0.0
Gln
3.431GlnAla: 3.431 ± 0.027
0.502GlnCys: 0.502 ± 0.008
2.209GlnAsp: 2.209 ± 0.018
2.272GlnGlu: 2.272 ± 0.021
1.352GlnPhe: 1.352 ± 0.015
2.53GlnGly: 2.53 ± 0.023
1.147GlnHis: 1.147 ± 0.015
1.927GlnIle: 1.927 ± 0.018
1.985GlnLys: 1.985 ± 0.02
3.672GlnLeu: 3.672 ± 0.024
0.936GlnMet: 0.936 ± 0.014
1.623GlnAsn: 1.623 ± 0.023
2.52GlnPro: 2.52 ± 0.027
2.45GlnGln: 2.45 ± 0.046
2.649GlnArg: 2.649 ± 0.023
3.141GlnSer: 3.141 ± 0.025
2.399GlnThr: 2.399 ± 0.019
2.286GlnVal: 2.286 ± 0.023
0.595GlnTrp: 0.595 ± 0.01
1.201GlnTyr: 1.201 ± 0.015
0.0GlnXaa: 0.0 ± 0.0
Arg
4.471ArgAla: 4.471 ± 0.028
0.834ArgCys: 0.834 ± 0.013
3.49ArgAsp: 3.49 ± 0.034
3.578ArgGlu: 3.578 ± 0.031
2.11ArgPhe: 2.11 ± 0.019
3.749ArgGly: 3.749 ± 0.03
1.681ArgHis: 1.681 ± 0.019
2.895ArgIle: 2.895 ± 0.024
3.331ArgLys: 3.331 ± 0.026
5.572ArgLeu: 5.572 ± 0.034
1.346ArgMet: 1.346 ± 0.014
2.311ArgAsn: 2.311 ± 0.019
3.35ArgPro: 3.35 ± 0.028
2.799ArgGln: 2.799 ± 0.026
5.157ArgArg: 5.157 ± 0.041
4.62ArgSer: 4.62 ± 0.036
3.299ArgThr: 3.299 ± 0.021
3.379ArgVal: 3.379 ± 0.026
1.014ArgTrp: 1.014 ± 0.012
1.678ArgTyr: 1.678 ± 0.018
0.0ArgXaa: 0.0 ± 0.0
Ser
6.354SerAla: 6.354 ± 0.037
1.041SerCys: 1.041 ± 0.014
4.135SerAsp: 4.135 ± 0.032
3.949SerGlu: 3.949 ± 0.029
3.014SerPhe: 3.014 ± 0.023
5.589SerGly: 5.589 ± 0.036
2.01SerHis: 2.01 ± 0.018
4.059SerIle: 4.059 ± 0.027
3.835SerLys: 3.835 ± 0.032
7.048SerLeu: 7.048 ± 0.032
1.798SerMet: 1.798 ± 0.018
3.058SerAsn: 3.058 ± 0.023
5.114SerPro: 5.114 ± 0.038
3.419SerGln: 3.419 ± 0.026
5.001SerArg: 5.001 ± 0.036
8.118SerSer: 8.118 ± 0.066
5.446SerThr: 5.446 ± 0.038
4.542SerVal: 4.542 ± 0.028
1.275SerTrp: 1.275 ± 0.016
2.051SerTyr: 2.051 ± 0.018
0.0SerXaa: 0.0 ± 0.0
Thr
5.186ThrAla: 5.186 ± 0.033
0.814ThrCys: 0.814 ± 0.012
2.907ThrAsp: 2.907 ± 0.023
3.067ThrGlu: 3.067 ± 0.025
2.213ThrPhe: 2.213 ± 0.018
4.245ThrGly: 4.245 ± 0.031
1.285ThrHis: 1.285 ± 0.016
3.185ThrIle: 3.185 ± 0.027
2.825ThrLys: 2.825 ± 0.022
5.211ThrLeu: 5.211 ± 0.033
1.266ThrMet: 1.266 ± 0.013
2.216ThrAsn: 2.216 ± 0.023
4.053ThrPro: 4.053 ± 0.032
2.142ThrGln: 2.142 ± 0.021
3.163ThrArg: 3.163 ± 0.024
5.267ThrSer: 5.267 ± 0.038
4.313ThrThr: 4.313 ± 0.048
3.778ThrVal: 3.778 ± 0.03
0.923ThrTrp: 0.923 ± 0.013
1.607ThrTyr: 1.607 ± 0.016
0.0ThrXaa: 0.0 ± 0.0
Val
5.39ValAla: 5.39 ± 0.035
0.932ValCys: 0.932 ± 0.013
3.854ValAsp: 3.854 ± 0.025
3.715ValGlu: 3.715 ± 0.029
2.508ValPhe: 2.508 ± 0.024
4.09ValGly: 4.09 ± 0.028
1.403ValHis: 1.403 ± 0.015
2.966ValIle: 2.966 ± 0.024
2.996ValLys: 2.996 ± 0.025
5.647ValLeu: 5.647 ± 0.035
1.393ValMet: 1.393 ± 0.013
2.352ValAsn: 2.352 ± 0.021
3.547ValPro: 3.547 ± 0.024
2.446ValGln: 2.446 ± 0.019
3.436ValArg: 3.436 ± 0.026
4.685ValSer: 4.685 ± 0.027
3.623ValThr: 3.623 ± 0.028
4.477ValVal: 4.477 ± 0.033
0.915ValTrp: 0.915 ± 0.014
1.705ValTyr: 1.705 ± 0.018
0.0ValXaa: 0.0 ± 0.0
Trp
1.245TrpAla: 1.245 ± 0.016
0.228TrpCys: 0.228 ± 0.006
0.962TrpAsp: 0.962 ± 0.012
0.863TrpGlu: 0.863 ± 0.013
0.592TrpPhe: 0.592 ± 0.009
0.983TrpGly: 0.983 ± 0.014
0.409TrpHis: 0.409 ± 0.008
0.821TrpIle: 0.821 ± 0.011
0.866TrpLys: 0.866 ± 0.012
1.44TrpLeu: 1.44 ± 0.017
0.405TrpMet: 0.405 ± 0.008
0.662TrpAsn: 0.662 ± 0.01
0.658TrpPro: 0.658 ± 0.011
0.631TrpGln: 0.631 ± 0.011
1.031TrpArg: 1.031 ± 0.014
1.098TrpSer: 1.098 ± 0.012
1.019TrpThr: 1.019 ± 0.015
0.972TrpVal: 0.972 ± 0.013
0.327TrpTrp: 0.327 ± 0.008
0.459TrpTyr: 0.459 ± 0.009
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.121TyrAla: 2.121 ± 0.021
0.465TyrCys: 0.465 ± 0.009
1.638TyrAsp: 1.638 ± 0.018
1.472TyrGlu: 1.472 ± 0.016
1.238TyrPhe: 1.238 ± 0.014
2.101TyrGly: 2.101 ± 0.02
0.744TyrHis: 0.744 ± 0.011
1.414TyrIle: 1.414 ± 0.016
1.168TyrLys: 1.168 ± 0.015
2.615TyrLeu: 2.615 ± 0.022
0.649TyrMet: 0.649 ± 0.009
1.16TyrAsn: 1.16 ± 0.014
1.408TyrPro: 1.408 ± 0.014
1.077TyrGln: 1.077 ± 0.014
1.613TyrArg: 1.613 ± 0.015
2.0TyrSer: 2.0 ± 0.02
1.581TyrThr: 1.581 ± 0.018
1.623TyrVal: 1.623 ± 0.016
0.491TyrTrp: 0.491 ± 0.011
0.937TyrTyr: 0.937 ± 0.014
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.002XaaXaa: 0.002 ± 0.001
Statistics based on 14143 proteins (6505054 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski