Bat coronavirus CDPHE15/USA/2006

Taxonomy: Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae; Alphacoronavirus; Colacovirus; Bat coronavirus CDPHE15

Average proteome isoelectric point is 6.53

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|S5Z1D1|S5Z1D1_9ALPC 3C-like proteinase OS=Bat coronavirus CDPHE15/USA/2006 OX=1384461 GN=PP1a PE=3 SV=1
MM1 pKa = 7.52KK2 pKa = 10.53LIILLCIGFAYY13 pKa = 10.4ANQRR17 pKa = 11.84NVGCSEE23 pKa = 3.91GGYY26 pKa = 10.12LDD28 pKa = 3.73PPKK31 pKa = 10.39RR32 pKa = 11.84LQLGLDD38 pKa = 3.27NVTALVPGALPLPGLWNCTVTSNFIYY64 pKa = 10.41GPTPRR69 pKa = 11.84PIGLFIMYY77 pKa = 8.79YY78 pKa = 10.79ASAQVAQFGISSTLRR93 pKa = 11.84RR94 pKa = 11.84SLSPYY99 pKa = 10.35SLYY102 pKa = 10.6FLNYY106 pKa = 8.94GNGRR110 pKa = 11.84RR111 pKa = 11.84HH112 pKa = 7.63IIRR115 pKa = 11.84ICKK118 pKa = 9.0WDD120 pKa = 3.97TDD122 pKa = 4.13KK123 pKa = 11.07MLQDD127 pKa = 3.58SDD129 pKa = 3.43ATTGYY134 pKa = 11.11DD135 pKa = 3.25CIANVRR141 pKa = 11.84INDD144 pKa = 3.39VVLEE148 pKa = 4.11HH149 pKa = 7.07GGRR152 pKa = 11.84QIYY155 pKa = 9.24GLSWSGNVVTLHH167 pKa = 4.97MLKK170 pKa = 10.37GIRR173 pKa = 11.84HH174 pKa = 5.01ITVPGAQYY182 pKa = 10.06WDD184 pKa = 3.92IIRR187 pKa = 11.84FSCGHH192 pKa = 6.81KK193 pKa = 10.23DD194 pKa = 3.44SCGHH198 pKa = 4.71QVVYY202 pKa = 8.99STNVFNVTVLNGFITNYY219 pKa = 9.91QVLPDD224 pKa = 3.71SGEE227 pKa = 3.9FSDD230 pKa = 5.28NLFTVGDD237 pKa = 4.53DD238 pKa = 3.85GSIPPSFGFNNWFVLSNSSSIISGTVVSNQPLRR271 pKa = 11.84LTCLWPIPSSTGALATIYY289 pKa = 10.79FNGTNGAQCNGFDD302 pKa = 4.3SNAPFDD308 pKa = 5.01AIRR311 pKa = 11.84FNLNGTLSGHH321 pKa = 5.69NFVSGFVLHH330 pKa = 7.0AANGATLGFSCTNSTDD346 pKa = 3.35APYY349 pKa = 10.78LRR351 pKa = 11.84QIPFGIGDD359 pKa = 3.76TPYY362 pKa = 10.11YY363 pKa = 10.47CYY365 pKa = 11.19LNVTTDD371 pKa = 3.03INSTMSFVGALPLNLRR387 pKa = 11.84EE388 pKa = 4.61IVIASNGDD396 pKa = 3.24VYY398 pKa = 11.19MNGYY402 pKa = 10.17RR403 pKa = 11.84YY404 pKa = 9.08FAAGDD409 pKa = 3.79LSSVDD414 pKa = 3.53VEE416 pKa = 4.87LPSQQVFGSTFWTIAFTVFEE436 pKa = 4.47TVLLEE441 pKa = 4.39VDD443 pKa = 3.48GTSINRR449 pKa = 11.84MLYY452 pKa = 10.15CDD454 pKa = 3.72NPLNRR459 pKa = 11.84VKK461 pKa = 10.65CSHH464 pKa = 5.61TQFDD468 pKa = 4.9LVDD471 pKa = 3.79GFYY474 pKa = 10.76PLTDD478 pKa = 2.53VDD480 pKa = 4.64LAVKK484 pKa = 10.14PFTFVTLPTFADD496 pKa = 3.34HH497 pKa = 6.83SFVYY501 pKa = 10.33FNFSLMFDD509 pKa = 4.32DD510 pKa = 5.11LNEE513 pKa = 4.18DD514 pKa = 3.64FRR516 pKa = 11.84LQSFNLTINGQLSYY530 pKa = 10.5CVQSRR535 pKa = 11.84QFTTSGSVRR544 pKa = 11.84TNTNHH549 pKa = 5.92QFGFYY554 pKa = 6.84TQRR557 pKa = 11.84AASNGCPFTIDD568 pKa = 3.24TLNNYY573 pKa = 7.78LTFGRR578 pKa = 11.84ICFSFGEE585 pKa = 4.41SGAGCGVDD593 pKa = 4.15VMVEE597 pKa = 3.81SQYY600 pKa = 12.11NMFKK604 pKa = 9.36VTTIFVSYY612 pKa = 10.94SEE614 pKa = 4.22GDD616 pKa = 3.62IIAGMPKK623 pKa = 9.47PSEE626 pKa = 4.44GIRR629 pKa = 11.84DD630 pKa = 3.47VSKK633 pKa = 10.75IHH635 pKa = 7.31LDD637 pKa = 3.37VCSTYY642 pKa = 10.67SIYY645 pKa = 11.25GHH647 pKa = 6.51TGDD650 pKa = 5.26GIIRR654 pKa = 11.84LTNDD658 pKa = 2.99TLLGGLYY665 pKa = 8.39YY666 pKa = 10.15TSPGGALLGFKK677 pKa = 10.4NVTTGEE683 pKa = 4.25IYY685 pKa = 10.72SVTPCSLTQQVAVVSDD701 pKa = 4.18EE702 pKa = 3.93IVGVVSSSANVSDD715 pKa = 3.66QFSFTYY721 pKa = 8.02TTVTEE726 pKa = 3.96QFYY729 pKa = 11.38YY730 pKa = 8.1MTDD733 pKa = 3.51GNSSCSEE740 pKa = 3.81PVLTYY745 pKa = 11.04SSLGVCKK752 pKa = 10.68DD753 pKa = 2.92GALRR757 pKa = 11.84ILQPRR762 pKa = 11.84EE763 pKa = 3.99DD764 pKa = 3.92TTQPTPIVSGVISIATNFTLSVVTEE789 pKa = 4.24YY790 pKa = 10.55IQLANTPISVDD801 pKa = 2.97CAMYY805 pKa = 10.43VCNGNPRR812 pKa = 11.84CNMLLAQYY820 pKa = 10.93SSACQTIEE828 pKa = 4.23NALQLSAKK836 pKa = 10.03LEE838 pKa = 4.54SIEE841 pKa = 4.04VTNMLTVSEE850 pKa = 5.24DD851 pKa = 3.22NLQIANISTFNGGGYY866 pKa = 10.45NFTNLMGTTYY876 pKa = 9.11STKK879 pKa = 10.65SVVEE883 pKa = 4.96DD884 pKa = 3.16ILFDD888 pKa = 3.77KK889 pKa = 11.09VVTSGLGTVDD899 pKa = 4.39ADD901 pKa = 4.53YY902 pKa = 10.68KK903 pKa = 10.81ACSNGLSIADD913 pKa = 4.03LVCAQYY919 pKa = 10.49YY920 pKa = 8.27QGVMVLPGVVDD931 pKa = 3.56AAKK934 pKa = 10.54LHH936 pKa = 6.26MYY938 pKa = 9.71SASLMGGMALGGVTAAAALPFSYY961 pKa = 10.43AVQARR966 pKa = 11.84LNYY969 pKa = 9.72VALQTDD975 pKa = 3.94VLQRR979 pKa = 11.84NQQILAEE986 pKa = 4.36SFNNAIGNITNAFASVNDD1004 pKa = 5.22AISQTAEE1011 pKa = 3.87GLSTVAEE1018 pKa = 4.35ALSKK1022 pKa = 10.66VQDD1025 pKa = 3.63VVNNQGMALNHH1036 pKa = 6.33LTLQLQNNFQAISSSIADD1054 pKa = 3.56IYY1056 pKa = 11.12RR1057 pKa = 11.84RR1058 pKa = 11.84LDD1060 pKa = 3.25QLTADD1065 pKa = 3.8AQVDD1069 pKa = 3.65RR1070 pKa = 11.84LINGRR1075 pKa = 11.84LAALNAFVSQTLTKK1089 pKa = 9.99YY1090 pKa = 10.58SQVQASRR1097 pKa = 11.84SLAKK1101 pKa = 10.31QKK1103 pKa = 10.63INEE1106 pKa = 4.48CVLSQSPRR1114 pKa = 11.84YY1115 pKa = 9.08GFCGDD1120 pKa = 3.65GGRR1123 pKa = 11.84HH1124 pKa = 5.01VFTVTQAAPQGILFLHH1140 pKa = 5.98TVLRR1144 pKa = 11.84PTGSVNVTAAAGICVDD1160 pKa = 3.52GAGYY1164 pKa = 11.02ALNQPGLVLIYY1175 pKa = 10.35QDD1177 pKa = 3.53GTYY1180 pKa = 10.64LITPRR1185 pKa = 11.84VMFEE1189 pKa = 3.61PRR1191 pKa = 11.84QPQISDD1197 pKa = 3.33FVRR1200 pKa = 11.84IEE1202 pKa = 4.28GCDD1205 pKa = 3.25VEE1207 pKa = 4.56YY1208 pKa = 11.02FNVTGEE1214 pKa = 4.21SLPDD1218 pKa = 3.53IFPDD1222 pKa = 5.29FIDD1225 pKa = 3.66VNKK1228 pKa = 9.33TLEE1231 pKa = 5.24DD1232 pKa = 3.61ILSQLQNNTGPKK1244 pKa = 9.75FDD1246 pKa = 4.18IDD1248 pKa = 3.92IFNATYY1254 pKa = 11.05LNLSSEE1260 pKa = 4.22IADD1263 pKa = 3.29LEE1265 pKa = 4.21MRR1267 pKa = 11.84SEE1269 pKa = 4.2SLHH1272 pKa = 5.37NTTEE1276 pKa = 3.98EE1277 pKa = 4.09LKK1279 pKa = 10.96RR1280 pKa = 11.84LIDD1283 pKa = 4.57NINSTLVDD1291 pKa = 4.3LEE1293 pKa = 3.91WLNRR1297 pKa = 11.84VEE1299 pKa = 5.97TYY1301 pKa = 10.41IKK1303 pKa = 9.23WPWWVWLLIAIALIFTVSLLLFCCIATGCCGCCGCCASCLTGCCKK1348 pKa = 10.37GPRR1351 pKa = 11.84LQPYY1355 pKa = 8.15EE1356 pKa = 4.76AIEE1359 pKa = 4.2KK1360 pKa = 9.87VHH1362 pKa = 5.3VQQ1364 pKa = 3.06

Molecular weight: 148.89 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|S5YGS4|S5YGS4_9ALPC Envelope small membrane protein OS=Bat coronavirus CDPHE15/USA/2006 OX=1384461 GN=E PE=3 SV=1
MM1 pKa = 7.64ASVKK5 pKa = 9.64FAKK8 pKa = 10.16NNRR11 pKa = 11.84RR12 pKa = 11.84GRR14 pKa = 11.84MEE16 pKa = 3.78YY17 pKa = 10.41SYY19 pKa = 10.63FAPLIINSDD28 pKa = 3.55QPIWKK33 pKa = 9.29VLPNNAVPVGKK44 pKa = 10.24GGKK47 pKa = 9.4DD48 pKa = 3.23EE49 pKa = 5.24QIGYY53 pKa = 9.25WNEE56 pKa = 3.57QPRR59 pKa = 11.84WRR61 pKa = 11.84MRR63 pKa = 11.84KK64 pKa = 7.43GQRR67 pKa = 11.84VDD69 pKa = 3.85VASKK73 pKa = 8.05WHH75 pKa = 6.62FYY77 pKa = 10.96YY78 pKa = 10.84LGTGPHH84 pKa = 6.25SEE86 pKa = 3.69EE87 pKa = 4.24QYY89 pKa = 10.56RR90 pKa = 11.84KK91 pKa = 10.32RR92 pKa = 11.84IDD94 pKa = 3.15GVYY97 pKa = 8.29WVAVNGAKK105 pKa = 9.64TSPTGLGTRR114 pKa = 11.84SAKK117 pKa = 9.37TKK119 pKa = 10.01PLEE122 pKa = 4.15LKK124 pKa = 10.67FNTKK128 pKa = 9.27IPKK131 pKa = 9.19EE132 pKa = 4.13VEE134 pKa = 4.1FVEE137 pKa = 4.64PTSPGSSRR145 pKa = 11.84ANSRR149 pKa = 11.84SQSRR153 pKa = 11.84GGSKK157 pKa = 10.13SRR159 pKa = 11.84NNSPRR164 pKa = 11.84RR165 pKa = 11.84GNQSKK170 pKa = 10.5SRR172 pKa = 11.84NSSKK176 pKa = 10.66NRR178 pKa = 11.84GGDD181 pKa = 3.15NRR183 pKa = 11.84SRR185 pKa = 11.84SSSGTRR191 pKa = 11.84DD192 pKa = 2.69QDD194 pKa = 4.04AIVAAVKK201 pKa = 10.22AALLGLGLGTDD212 pKa = 4.06SNSGASGKK220 pKa = 10.21ASKK223 pKa = 10.78ANSGTSTPKK232 pKa = 9.99PKK234 pKa = 9.88PAATPKK240 pKa = 10.66SPSTPKK246 pKa = 10.45SQLEE250 pKa = 3.89RR251 pKa = 11.84PEE253 pKa = 4.03WKK255 pKa = 9.89RR256 pKa = 11.84VPDD259 pKa = 3.54SDD261 pKa = 5.32CSVEE265 pKa = 4.07QCFGPRR271 pKa = 11.84GGFKK275 pKa = 10.84NFGSADD281 pKa = 3.43FVQYY285 pKa = 10.46GVAAKK290 pKa = 10.1GYY292 pKa = 7.96PQAAALTPTSAALLFGGNVQVQEE315 pKa = 4.42LSDD318 pKa = 4.97DD319 pKa = 3.62IEE321 pKa = 3.82ITYY324 pKa = 8.33TYY326 pKa = 10.99KK327 pKa = 8.4MTVPKK332 pKa = 10.12SDD334 pKa = 3.48KK335 pKa = 10.19NLEE338 pKa = 4.17VFLSNVNAYY347 pKa = 9.61KK348 pKa = 10.07EE349 pKa = 4.33AKK351 pKa = 8.67PQRR354 pKa = 11.84EE355 pKa = 4.15PKK357 pKa = 9.72KK358 pKa = 10.81KK359 pKa = 9.47KK360 pKa = 9.94DD361 pKa = 3.34RR362 pKa = 11.84SSRR365 pKa = 11.84PPTPAPSAPVASGNAEE381 pKa = 4.3PIYY384 pKa = 11.02ADD386 pKa = 3.74VQPQGQTEE394 pKa = 4.11PVYY397 pKa = 10.55EE398 pKa = 4.8NPDD401 pKa = 3.29QYY403 pKa = 11.47LGGVDD408 pKa = 3.5IVNEE412 pKa = 4.36VYY414 pKa = 11.11GNLPDD419 pKa = 4.58NSQSTAA425 pKa = 3.02

Molecular weight: 46.19 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

13299

74

6825

1899.9

210.16

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.331 ± 0.266

3.444 ± 0.491

5.677 ± 0.331

3.812 ± 0.165

5.76 ± 0.297

7.053 ± 0.235

1.948 ± 0.225

4.579 ± 0.343

5.03 ± 0.549

8.82 ± 0.357

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.023 ± 0.192

5.233 ± 0.269

3.632 ± 0.484

2.918 ± 0.37

3.79 ± 0.275

7.392 ± 0.399

6.068 ± 0.293

9.873 ± 0.485

1.188 ± 0.139

4.429 ± 0.142
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski