Human papillomavirus sp.

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; unclassified Papillomaviridae; Human papillomavirus types

Average proteome isoelectric point is 6.44

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A2D2AMJ6|A0A2D2AMJ6_9PAPI E4 OS=Human papillomavirus sp. OX=192971 GN=E4 PE=4 SV=1
MM1 pKa = 7.29RR2 pKa = 11.84QVSNFSSINNILQEE16 pKa = 4.32EE17 pKa = 4.83EE18 pKa = 3.96PTIIDD23 pKa = 3.83LFCYY27 pKa = 10.52EE28 pKa = 4.46EE29 pKa = 4.2VALSDD34 pKa = 4.02EE35 pKa = 4.63EE36 pKa = 5.09EE37 pKa = 4.38EE38 pKa = 4.38SQQVQQAYY46 pKa = 10.11LVTVQCAHH54 pKa = 6.98CLNLVTFNYY63 pKa = 9.46WADD66 pKa = 3.51LPAIRR71 pKa = 11.84EE72 pKa = 4.15LQQLLFDD79 pKa = 4.55CVHH82 pKa = 6.58FVCEE86 pKa = 3.99SCAAEE91 pKa = 4.09LQQ93 pKa = 3.69

Molecular weight: 10.75 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A2D2AMG1|A0A2D2AMG1_9PAPI Minor capsid protein L2 OS=Human papillomavirus sp. OX=192971 GN=L2 PE=3 SV=1
MM1 pKa = 7.52EE2 pKa = 5.36NLVQRR7 pKa = 11.84LEE9 pKa = 4.16SLQEE13 pKa = 3.95RR14 pKa = 11.84LLSLYY19 pKa = 10.04EE20 pKa = 3.82QDD22 pKa = 4.89SNDD25 pKa = 3.17IQDD28 pKa = 5.09QITHH32 pKa = 5.15WTLVKK37 pKa = 10.26QEE39 pKa = 3.9QLIYY43 pKa = 10.52HH44 pKa = 6.17YY45 pKa = 10.82ARR47 pKa = 11.84KK48 pKa = 10.11NGIRR52 pKa = 11.84RR53 pKa = 11.84LGMQSLPTLAASEE66 pKa = 4.47TKK68 pKa = 10.25AKK70 pKa = 10.11QAIEE74 pKa = 4.7MILQLQSLANSPFGLEE90 pKa = 3.82SWSLHH95 pKa = 4.55DD96 pKa = 3.72TSRR99 pKa = 11.84EE100 pKa = 3.87RR101 pKa = 11.84YY102 pKa = 4.85TTEE105 pKa = 4.17PEE107 pKa = 3.88NTFKK111 pKa = 10.9KK112 pKa = 10.29QPQTLLITFDD122 pKa = 3.62NDD124 pKa = 2.99RR125 pKa = 11.84DD126 pKa = 3.72NSVEE130 pKa = 4.14HH131 pKa = 5.71TVWTYY136 pKa = 11.26VYY138 pKa = 9.26YY139 pKa = 10.95QNGDD143 pKa = 4.27DD144 pKa = 3.39IWHH147 pKa = 6.68KK148 pKa = 10.71EE149 pKa = 3.85EE150 pKa = 4.9SSVDD154 pKa = 3.25EE155 pKa = 4.18KK156 pKa = 11.45GIYY159 pKa = 8.24FLKK162 pKa = 10.92YY163 pKa = 9.26GVEE166 pKa = 3.45KK167 pKa = 10.28HH168 pKa = 6.29YY169 pKa = 10.95YY170 pKa = 8.32VQFANEE176 pKa = 3.7ATRR179 pKa = 11.84YY180 pKa = 8.36SKK182 pKa = 10.7KK183 pKa = 10.78GEE185 pKa = 3.83YY186 pKa = 8.75TVQFKK191 pKa = 9.33NQRR194 pKa = 11.84HH195 pKa = 5.73SYY197 pKa = 8.6NVSSVSSTSGSPGSPDD213 pKa = 3.02STKK216 pKa = 11.28ANASGSNTRR225 pKa = 11.84STSEE229 pKa = 3.89EE230 pKa = 3.99GPEE233 pKa = 3.43RR234 pKa = 11.84SIRR237 pKa = 11.84SRR239 pKa = 11.84TFGQRR244 pKa = 11.84PSTSPRR250 pKa = 11.84VSSRR254 pKa = 11.84RR255 pKa = 11.84GGQQGKK261 pKa = 8.95PDD263 pKa = 3.65TGADD267 pKa = 3.78SDD269 pKa = 4.52SGLAPPSPEE278 pKa = 3.74EE279 pKa = 3.87VGSRR283 pKa = 11.84TTQPTRR289 pKa = 11.84RR290 pKa = 11.84GQSRR294 pKa = 11.84LRR296 pKa = 11.84VLLQEE301 pKa = 4.48ARR303 pKa = 11.84DD304 pKa = 3.86PLVLCLKK311 pKa = 10.45GGPNQLKK318 pKa = 9.96CLRR321 pKa = 11.84YY322 pKa = 8.85RR323 pKa = 11.84LKK325 pKa = 10.55KK326 pKa = 9.25QHH328 pKa = 6.59HH329 pKa = 6.29KK330 pKa = 10.8LFTKK334 pKa = 10.47ISTTWHH340 pKa = 5.71WVHH343 pKa = 5.7NTSTDD348 pKa = 3.25RR349 pKa = 11.84VGNARR354 pKa = 11.84MLIQFVNEE362 pKa = 3.87DD363 pKa = 3.19QRR365 pKa = 11.84NRR367 pKa = 11.84FLDD370 pKa = 4.33EE371 pKa = 4.58IIVPKK376 pKa = 10.47DD377 pKa = 2.92IIVYY381 pKa = 9.21RR382 pKa = 11.84GYY384 pKa = 10.89FRR386 pKa = 11.84GYY388 pKa = 10.23

Molecular weight: 44.65 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2384

93

616

340.6

38.66

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.076 ± 0.648

1.762 ± 0.671

5.956 ± 0.331

6.669 ± 0.64

4.74 ± 0.488

5.495 ± 0.882

2.181 ± 0.269

5.453 ± 0.839

5.201 ± 0.77

9.48 ± 1.578

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.342 ± 0.264

5.034 ± 0.518

5.789 ± 1.006

4.992 ± 0.819

5.956 ± 0.717

7.592 ± 0.864

6.711 ± 0.733

6.04 ± 0.371

1.258 ± 0.363

3.272 ± 0.417
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski