Amino acid dipepetide frequency for Hypocrea atroviridis (strain ATCC 20476 / IMI 206040) (Trichoderma atroviride)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.927AlaAla: 9.927 ± 0.068	1.125AlaCys: 1.125 ± 0.016	4.427AlaAsp: 4.427 ± 0.034	5.151AlaGlu: 5.151 ± 0.037	3.251AlaPhe: 3.251 ± 0.027	5.75AlaGly: 5.75 ± 0.038	1.785AlaHis: 1.785 ± 0.02	4.679AlaIle: 4.679 ± 0.035	4.333AlaLys: 4.333 ± 0.035	7.897AlaLeu: 7.897 ± 0.041	2.079AlaMet: 2.079 ± 0.023	3.189AlaAsn: 3.189 ± 0.026	4.584AlaPro: 4.584 ± 0.036	3.511AlaGln: 3.511 ± 0.03	4.746AlaArg: 4.746 ± 0.032	7.615AlaSer: 7.615 ± 0.049	5.346AlaThr: 5.346 ± 0.038	5.48AlaVal: 5.48 ± 0.033	1.222AlaTrp: 1.222 ± 0.022	2.268AlaTyr: 2.268 ± 0.025	0.0AlaXaa: 0.0 ± 0.0
Cys	0.947CysAla: 0.947 ± 0.015	0.281CysCys: 0.281 ± 0.009	0.692CysAsp: 0.692 ± 0.011	0.613CysGlu: 0.613 ± 0.012	0.579CysPhe: 0.579 ± 0.012	0.983CysGly: 0.983 ± 0.017	0.345CysHis: 0.345 ± 0.009	0.763CysIle: 0.763 ± 0.014	0.533CysLys: 0.533 ± 0.011	1.299CysLeu: 1.299 ± 0.016	0.269CysMet: 0.269 ± 0.006	0.474CysAsn: 0.474 ± 0.011	0.65CysPro: 0.65 ± 0.015	0.501CysGln: 0.501 ± 0.009	0.756CysArg: 0.756 ± 0.014	0.995CysSer: 0.995 ± 0.015	0.686CysThr: 0.686 ± 0.012	0.801CysVal: 0.801 ± 0.013	0.224CysTrp: 0.224 ± 0.007	0.383CysTyr: 0.383 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	4.959AspAla: 4.959 ± 0.033	0.671AspCys: 0.671 ± 0.011	4.427AspAsp: 4.427 ± 0.049	4.614AspGlu: 4.614 ± 0.04	2.286AspPhe: 2.286 ± 0.022	4.245AspGly: 4.245 ± 0.032	1.185AspHis: 1.185 ± 0.017	3.284AspIle: 3.284 ± 0.023	2.603AspLys: 2.603 ± 0.026	4.975AspLeu: 4.975 ± 0.035	1.356AspMet: 1.356 ± 0.017	1.972AspAsn: 1.972 ± 0.019	3.034AspPro: 3.034 ± 0.028	1.845AspGln: 1.845 ± 0.019	2.877AspArg: 2.877 ± 0.03	4.143AspSer: 4.143 ± 0.026	2.853AspThr: 2.853 ± 0.021	3.763AspVal: 3.763 ± 0.034	0.897AspTrp: 0.897 ± 0.013	1.642AspTyr: 1.642 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	5.672GluAla: 5.672 ± 0.036	0.636GluCys: 0.636 ± 0.012	4.17GluAsp: 4.17 ± 0.037	5.305GluGlu: 5.305 ± 0.058	2.017GluPhe: 2.017 ± 0.02	3.504GluGly: 3.504 ± 0.025	1.354GluHis: 1.354 ± 0.017	3.169GluIle: 3.169 ± 0.029	3.635GluLys: 3.635 ± 0.037	5.255GluLeu: 5.255 ± 0.037	1.519GluMet: 1.519 ± 0.017	2.252GluAsn: 2.252 ± 0.021	2.663GluPro: 2.663 ± 0.028	2.45GluGln: 2.45 ± 0.023	3.688GluArg: 3.688 ± 0.032	4.237GluSer: 4.237 ± 0.031	3.419GluThr: 3.419 ± 0.026	3.316GluVal: 3.316 ± 0.03	0.908GluTrp: 0.908 ± 0.012	1.665GluTyr: 1.665 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	3.14PheAla: 3.14 ± 0.021	0.59PheCys: 0.59 ± 0.011	2.377PheAsp: 2.377 ± 0.021	2.159PheGlu: 2.159 ± 0.02	1.713PhePhe: 1.713 ± 0.022	2.928PheGly: 2.928 ± 0.027	0.93PheHis: 0.93 ± 0.014	2.01PheIle: 2.01 ± 0.023	1.605PheLys: 1.605 ± 0.018	3.495PheLeu: 3.495 ± 0.031	0.809PheMet: 0.809 ± 0.014	1.519PheAsn: 1.519 ± 0.016	1.94PhePro: 1.94 ± 0.019	1.488PheGln: 1.488 ± 0.017	1.905PheArg: 1.905 ± 0.019	3.132PheSer: 3.132 ± 0.027	2.161PheThr: 2.161 ± 0.02	2.423PheVal: 2.423 ± 0.023	0.668PheTrp: 0.668 ± 0.012	1.163PheTyr: 1.163 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	5.412GlyAla: 5.412 ± 0.039	0.875GlyCys: 0.875 ± 0.017	3.67GlyAsp: 3.67 ± 0.034	3.613GlyGlu: 3.613 ± 0.03	2.844GlyPhe: 2.844 ± 0.025	5.613GlyGly: 5.613 ± 0.066	1.72GlyHis: 1.72 ± 0.02	3.721GlyIle: 3.721 ± 0.032	3.466GlyLys: 3.466 ± 0.033	6.1GlyLeu: 6.1 ± 0.041	1.519GlyMet: 1.519 ± 0.02	2.62GlyAsn: 2.62 ± 0.025	3.156GlyPro: 3.156 ± 0.034	2.562GlyGln: 2.562 ± 0.024	3.997GlyArg: 3.997 ± 0.032	5.779GlySer: 5.779 ± 0.041	3.776GlyThr: 3.776 ± 0.03	4.272GlyVal: 4.272 ± 0.031	1.189GlyTrp: 1.189 ± 0.016	2.141GlyTyr: 2.141 ± 0.026	0.0GlyXaa: 0.0 ± 0.0
His	1.774HisAla: 1.774 ± 0.02	0.343HisCys: 0.343 ± 0.008	1.344HisAsp: 1.344 ± 0.016	1.283HisGlu: 1.283 ± 0.015	0.943HisPhe: 0.943 ± 0.014	1.714HisGly: 1.714 ± 0.02	0.853HisHis: 0.853 ± 0.018	1.257HisIle: 1.257 ± 0.017	0.939HisLys: 0.939 ± 0.015	2.277HisLeu: 2.277 ± 0.022	0.516HisMet: 0.516 ± 0.01	0.87HisAsn: 0.87 ± 0.012	1.512HisPro: 1.512 ± 0.018	1.04HisGln: 1.04 ± 0.017	1.471HisArg: 1.471 ± 0.017	1.773HisSer: 1.773 ± 0.022	1.182HisThr: 1.182 ± 0.015	1.485HisVal: 1.485 ± 0.021	0.359HisTrp: 0.359 ± 0.008	0.711HisTyr: 0.711 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.452IleAla: 4.452 ± 0.035	0.813IleCys: 0.813 ± 0.015	3.042IleAsp: 3.042 ± 0.024	2.997IleGlu: 2.997 ± 0.032	2.152IlePhe: 2.152 ± 0.023	3.369IleGly: 3.369 ± 0.03	1.293IleHis: 1.293 ± 0.016	2.799IleIle: 2.799 ± 0.026	2.41IleLys: 2.41 ± 0.022	4.743IleLeu: 4.743 ± 0.036	1.087IleMet: 1.087 ± 0.013	1.975IleAsn: 1.975 ± 0.019	2.969IlePro: 2.969 ± 0.024	2.102IleGln: 2.102 ± 0.027	2.934IleArg: 2.934 ± 0.024	4.096IleSer: 4.096 ± 0.034	2.922IleThr: 2.922 ± 0.027	3.272IleVal: 3.272 ± 0.029	0.794IleTrp: 0.794 ± 0.014	1.487IleTyr: 1.487 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.523LysAla: 4.523 ± 0.033	0.519LysCys: 0.519 ± 0.012	2.953LysAsp: 2.953 ± 0.033	3.328LysGlu: 3.328 ± 0.033	1.558LysPhe: 1.558 ± 0.017	2.969LysGly: 2.969 ± 0.03	1.125LysHis: 1.125 ± 0.017	2.409LysIle: 2.409 ± 0.021	3.406LysLys: 3.406 ± 0.042	4.341LysLeu: 4.341 ± 0.031	1.077LysMet: 1.077 ± 0.015	1.814LysAsn: 1.814 ± 0.018	2.643LysPro: 2.643 ± 0.024	1.906LysGln: 1.906 ± 0.022	3.36LysArg: 3.36 ± 0.031	3.57LysSer: 3.57 ± 0.03	2.911LysThr: 2.911 ± 0.021	2.779LysVal: 2.779 ± 0.026	0.698LysTrp: 0.698 ± 0.01	1.426LysTyr: 1.426 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	8.05LeuAla: 8.05 ± 0.043	1.25LeuCys: 1.25 ± 0.018	5.315LeuAsp: 5.315 ± 0.037	5.542LeuGlu: 5.542 ± 0.04	3.452LeuPhe: 3.452 ± 0.033	6.032LeuGly: 6.032 ± 0.04	2.214LeuHis: 2.214 ± 0.022	4.194LeuIle: 4.194 ± 0.033	4.338LeuLys: 4.338 ± 0.032	8.605LeuLeu: 8.605 ± 0.067	1.857LeuMet: 1.857 ± 0.019	3.205LeuAsn: 3.205 ± 0.027	5.331LeuPro: 5.331 ± 0.033	3.97LeuGln: 3.97 ± 0.034	5.559LeuArg: 5.559 ± 0.04	7.429LeuSer: 7.429 ± 0.044	4.69LeuThr: 4.69 ± 0.032	5.501LeuVal: 5.501 ± 0.045	1.29LeuTrp: 1.29 ± 0.016	2.452LeuTyr: 2.452 ± 0.025	0.0LeuXaa: 0.0 ± 0.0
Met	2.419MetAla: 2.419 ± 0.02	0.244MetCys: 0.244 ± 0.006	1.286MetAsp: 1.286 ± 0.018	1.323MetGlu: 1.323 ± 0.016	0.743MetPhe: 0.743 ± 0.013	1.49MetGly: 1.49 ± 0.018	0.464MetHis: 0.464 ± 0.009	1.017MetIle: 1.017 ± 0.015	1.062MetLys: 1.062 ± 0.016	1.942MetLeu: 1.942 ± 0.02	0.619MetMet: 0.619 ± 0.011	0.84MetAsn: 0.84 ± 0.013	1.343MetPro: 1.343 ± 0.019	0.881MetGln: 0.881 ± 0.015	1.283MetArg: 1.283 ± 0.017	1.858MetSer: 1.858 ± 0.019	1.272MetThr: 1.272 ± 0.017	1.285MetVal: 1.285 ± 0.015	0.277MetTrp: 0.277 ± 0.008	0.535MetTyr: 0.535 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.239AsnAla: 3.239 ± 0.027	0.474AsnCys: 0.474 ± 0.009	2.026AsnAsp: 2.026 ± 0.02	2.051AsnGlu: 2.051 ± 0.022	1.433AsnPhe: 1.433 ± 0.016	3.056AsnGly: 3.056 ± 0.031	0.873AsnHis: 0.873 ± 0.012	2.16AsnIle: 2.16 ± 0.021	1.692AsnLys: 1.692 ± 0.022	3.319AsnLeu: 3.319 ± 0.026	0.908AsnMet: 0.908 ± 0.013	1.631AsnAsn: 1.631 ± 0.023	2.34AsnPro: 2.34 ± 0.022	1.376AsnGln: 1.376 ± 0.019	1.959AsnArg: 1.959 ± 0.024	2.856AsnSer: 2.856 ± 0.026	2.133AsnThr: 2.133 ± 0.021	2.365AsnVal: 2.365 ± 0.024	0.6AsnTrp: 0.6 ± 0.01	1.113AsnTyr: 1.113 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	4.953ProAla: 4.953 ± 0.037	0.53ProCys: 0.53 ± 0.011	3.065ProAsp: 3.065 ± 0.028	3.591ProGlu: 3.591 ± 0.03	2.05ProPhe: 2.05 ± 0.022	3.705ProGly: 3.705 ± 0.033	1.227ProHis: 1.227 ± 0.016	2.565ProIle: 2.565 ± 0.027	2.623ProLys: 2.623 ± 0.028	4.728ProLeu: 4.728 ± 0.034	1.076ProMet: 1.076 ± 0.015	2.195ProAsn: 2.195 ± 0.022	4.682ProPro: 4.682 ± 0.074	2.359ProGln: 2.359 ± 0.025	3.168ProArg: 3.168 ± 0.032	5.581ProSer: 5.581 ± 0.044	3.561ProThr: 3.561 ± 0.033	3.349ProVal: 3.349 ± 0.026	0.762ProTrp: 0.762 ± 0.013	1.467ProTyr: 1.467 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	3.572GlnAla: 3.572 ± 0.035	0.463GlnCys: 0.463 ± 0.01	2.124GlnAsp: 2.124 ± 0.02	2.327GlnGlu: 2.327 ± 0.021	1.374GlnPhe: 1.374 ± 0.018	2.466GlnGly: 2.466 ± 0.025	1.066GlnHis: 1.066 ± 0.017	1.943GlnIle: 1.943 ± 0.017	2.012GlnLys: 2.012 ± 0.022	3.633GlnLeu: 3.633 ± 0.03	0.929GlnMet: 0.929 ± 0.015	1.568GlnAsn: 1.568 ± 0.017	2.471GlnPro: 2.471 ± 0.029	2.553GlnGln: 2.553 ± 0.053	2.633GlnArg: 2.633 ± 0.027	3.117GlnSer: 3.117 ± 0.024	2.294GlnThr: 2.294 ± 0.022	2.203GlnVal: 2.203 ± 0.02	0.615GlnTrp: 0.615 ± 0.011	1.191GlnTyr: 1.191 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	4.504ArgAla: 4.504 ± 0.031	0.731ArgCys: 0.731 ± 0.014	3.36ArgAsp: 3.36 ± 0.037	3.608ArgGlu: 3.608 ± 0.034	2.137ArgPhe: 2.137 ± 0.02	3.641ArgGly: 3.641 ± 0.034	1.56ArgHis: 1.56 ± 0.018	2.976ArgIle: 2.976 ± 0.024	3.234ArgLys: 3.234 ± 0.03	5.525ArgLeu: 5.525 ± 0.042	1.27ArgMet: 1.27 ± 0.015	2.201ArgAsn: 2.201 ± 0.023	3.333ArgPro: 3.333 ± 0.031	2.6ArgGln: 2.6 ± 0.024	4.812ArgArg: 4.812 ± 0.045	4.5ArgSer: 4.5 ± 0.038	2.976ArgThr: 2.976 ± 0.023	3.239ArgVal: 3.239 ± 0.024	0.904ArgTrp: 0.904 ± 0.014	1.653ArgTyr: 1.653 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	6.711SerAla: 6.711 ± 0.042	0.953SerCys: 0.953 ± 0.015	4.24SerAsp: 4.24 ± 0.03	4.107SerGlu: 4.107 ± 0.029	3.121SerPhe: 3.121 ± 0.028	5.595SerGly: 5.595 ± 0.047	1.955SerHis: 1.955 ± 0.02	4.24SerIle: 4.24 ± 0.029	3.834SerLys: 3.834 ± 0.036	7.381SerLeu: 7.381 ± 0.041	1.757SerMet: 1.757 ± 0.02	3.082SerAsn: 3.082 ± 0.028	5.126SerPro: 5.126 ± 0.047	3.356SerGln: 3.356 ± 0.031	4.866SerArg: 4.866 ± 0.04	8.622SerSer: 8.622 ± 0.078	5.201SerThr: 5.201 ± 0.044	4.52SerVal: 4.52 ± 0.029	1.188SerTrp: 1.188 ± 0.018	2.133SerTyr: 2.133 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	5.279ThrAla: 5.279 ± 0.038	0.783ThrCys: 0.783 ± 0.014	2.762ThrAsp: 2.762 ± 0.023	3.012ThrGlu: 3.012 ± 0.027	2.239ThrPhe: 2.239 ± 0.023	4.0ThrGly: 4.0 ± 0.031	1.217ThrHis: 1.217 ± 0.016	3.133ThrIle: 3.133 ± 0.032	2.64ThrLys: 2.64 ± 0.022	5.12ThrLeu: 5.12 ± 0.037	1.197ThrMet: 1.197 ± 0.017	2.098ThrAsn: 2.098 ± 0.02	3.922ThrPro: 3.922 ± 0.031	1.995ThrGln: 1.995 ± 0.018	2.966ThrArg: 2.966 ± 0.022	4.96ThrSer: 4.96 ± 0.045	3.898ThrThr: 3.898 ± 0.036	3.597ThrVal: 3.597 ± 0.03	0.862ThrTrp: 0.862 ± 0.013	1.605ThrTyr: 1.605 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	5.393ValAla: 5.393 ± 0.036	0.835ValCys: 0.835 ± 0.014	3.696ValAsp: 3.696 ± 0.026	3.733ValGlu: 3.733 ± 0.029	2.477ValPhe: 2.477 ± 0.024	3.887ValGly: 3.887 ± 0.03	1.344ValHis: 1.344 ± 0.016	3.079ValIle: 3.079 ± 0.027	2.941ValLys: 2.941 ± 0.028	5.555ValLeu: 5.555 ± 0.039	1.305ValMet: 1.305 ± 0.017	2.243ValAsn: 2.243 ± 0.021	3.42ValPro: 3.42 ± 0.029	2.355ValGln: 2.355 ± 0.023	3.215ValArg: 3.215 ± 0.025	4.557ValSer: 4.557 ± 0.033	3.466ValThr: 3.466 ± 0.028	4.251ValVal: 4.251 ± 0.037	0.88ValTrp: 0.88 ± 0.016	1.748ValTyr: 1.748 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.226TrpAla: 1.226 ± 0.017	0.204TrpCys: 0.204 ± 0.007	0.962TrpAsp: 0.962 ± 0.018	0.866TrpGlu: 0.866 ± 0.014	0.558TrpPhe: 0.558 ± 0.012	0.944TrpGly: 0.944 ± 0.015	0.376TrpHis: 0.376 ± 0.009	0.833TrpIle: 0.833 ± 0.014	0.829TrpLys: 0.829 ± 0.013	1.416TrpLeu: 1.416 ± 0.02	0.379TrpMet: 0.379 ± 0.01	0.689TrpAsn: 0.689 ± 0.012	0.652TrpPro: 0.652 ± 0.012	0.591TrpGln: 0.591 ± 0.01	0.965TrpArg: 0.965 ± 0.014	1.08TrpSer: 1.08 ± 0.016	0.916TrpThr: 0.916 ± 0.015	0.876TrpVal: 0.876 ± 0.013	0.299TrpTrp: 0.299 ± 0.008	0.429TrpTyr: 0.429 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.212TyrAla: 2.212 ± 0.021	0.455TyrCys: 0.455 ± 0.01	1.692TyrAsp: 1.692 ± 0.022	1.61TyrGlu: 1.61 ± 0.02	1.226TyrPhe: 1.226 ± 0.018	2.153TyrGly: 2.153 ± 0.023	0.761TyrHis: 0.761 ± 0.013	1.482TyrIle: 1.482 ± 0.017	1.181TyrLys: 1.181 ± 0.017	2.668TyrLeu: 2.668 ± 0.022	0.652TyrMet: 0.652 ± 0.012	1.167TyrAsn: 1.167 ± 0.015	1.464TyrPro: 1.464 ± 0.015	1.111TyrGln: 1.111 ± 0.016	1.606TyrArg: 1.606 ± 0.018	2.089TyrSer: 2.089 ± 0.022	1.624TyrThr: 1.624 ± 0.02	1.601TyrVal: 1.601 ± 0.017	0.457TyrTrp: 0.457 ± 0.009	0.953TyrTyr: 0.953 ± 0.017	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 11815 proteins (5388752 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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