Amino acid dipepetide frequency for Torque teno sus virus 1a

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.403AlaAla: 8.403 ± 24.026
0.0AlaCys: 0.0 ± 0.0
0.0AlaAsp: 0.0 ± 0.0
1.401AlaGlu: 1.401 ± 0.708
4.202AlaPhe: 4.202 ± 2.123
7.003AlaGly: 7.003 ± 3.529
0.0AlaHis: 0.0 ± 0.0
4.202AlaIle: 4.202 ± 12.013
1.401AlaLys: 1.401 ± 0.708
2.801AlaLeu: 2.801 ± 5.653
0.0AlaMet: 0.0 ± 0.0
0.0AlaAsn: 0.0 ± 0.0
0.0AlaPro: 0.0 ± 0.0
4.202AlaGln: 4.202 ± 2.123
4.202AlaArg: 4.202 ± 2.123
1.401AlaSer: 1.401 ± 0.708
2.801AlaThr: 2.801 ± 5.653
1.401AlaVal: 1.401 ± 6.361
2.801AlaTrp: 2.801 ± 5.653
4.202AlaTyr: 4.202 ± 2.123
0.0AlaXaa: 0.0 ± 0.0
Cys
4.202CysAla: 4.202 ± 4.945
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.401CysGly: 1.401 ± 6.361
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
2.801CysLys: 2.801 ± 1.416
2.801CysLeu: 2.801 ± 1.416
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.401CysGln: 1.401 ± 0.708
1.401CysArg: 1.401 ± 6.361
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
2.801CysVal: 2.801 ± 1.416
0.0CysTrp: 0.0 ± 0.0
1.401CysTyr: 1.401 ± 0.708
0.0CysXaa: 0.0 ± 0.0
Asp
2.801AspAla: 2.801 ± 12.721
1.401AspCys: 1.401 ± 6.361
0.0AspAsp: 0.0 ± 0.0
1.401AspGlu: 1.401 ± 0.708
5.602AspPhe: 5.602 ± 2.831
8.403AspGly: 8.403 ± 16.958
1.401AspHis: 1.401 ± 6.361
1.401AspIle: 1.401 ± 0.708
4.202AspLys: 4.202 ± 2.123
4.202AspLeu: 4.202 ± 2.123
1.401AspMet: 1.401 ± 0.708
2.801AspAsn: 2.801 ± 1.416
4.202AspPro: 4.202 ± 4.945
1.401AspGln: 1.401 ± 6.361
7.003AspArg: 7.003 ± 3.539
1.401AspSer: 1.401 ± 0.708
5.602AspThr: 5.602 ± 4.237
1.401AspVal: 1.401 ± 0.708
0.0AspTrp: 0.0 ± 0.0
2.801AspTyr: 2.801 ± 1.416
0.0AspXaa: 0.0 ± 0.0
Glu
2.801GluAla: 2.801 ± 5.653
0.0GluCys: 0.0 ± 0.0
5.602GluAsp: 5.602 ± 4.237
7.003GluGlu: 7.003 ± 3.529
4.202GluPhe: 4.202 ± 2.123
2.801GluGly: 2.801 ± 5.653
4.202GluHis: 4.202 ± 2.123
0.0GluIle: 0.0 ± 0.0
4.202GluLys: 4.202 ± 2.123
2.801GluLeu: 2.801 ± 1.416
4.202GluMet: 4.202 ± 1.849
4.202GluAsn: 4.202 ± 2.123
4.202GluPro: 4.202 ± 2.123
0.0GluGln: 0.0 ± 0.0
4.202GluArg: 4.202 ± 4.945
2.801GluSer: 2.801 ± 1.416
2.801GluThr: 2.801 ± 1.416
0.0GluVal: 0.0 ± 0.0
1.401GluTrp: 1.401 ± 0.708
2.801GluTyr: 2.801 ± 1.416
0.0GluXaa: 0.0 ± 0.0
Phe
2.801PheAla: 2.801 ± 1.416
1.401PheCys: 1.401 ± 0.708
1.401PheAsp: 1.401 ± 0.708
0.0PheGlu: 0.0 ± 0.0
2.801PhePhe: 2.801 ± 1.416
7.003PheGly: 7.003 ± 3.539
0.0PheHis: 0.0 ± 0.0
1.401PheIle: 1.401 ± 0.708
2.801PheLys: 2.801 ± 1.416
2.801PheLeu: 2.801 ± 5.653
0.0PheMet: 0.0 ± 0.0
7.003PheAsn: 7.003 ± 3.539
0.0PhePro: 0.0 ± 0.0
4.202PheGln: 4.202 ± 2.123
4.202PheArg: 4.202 ± 2.123
1.401PheSer: 1.401 ± 0.708
1.401PheThr: 1.401 ± 0.708
2.801PheVal: 2.801 ± 1.416
1.401PheTrp: 1.401 ± 0.708
1.401PheTyr: 1.401 ± 0.708
0.0PheXaa: 0.0 ± 0.0
Gly
1.401GlyAla: 1.401 ± 0.708
1.401GlyCys: 1.401 ± 0.708
8.403GlyAsp: 8.403 ± 16.958
4.202GlyGlu: 4.202 ± 2.123
1.401GlyPhe: 1.401 ± 0.708
11.204GlyGly: 11.204 ± 1.406
4.202GlyHis: 4.202 ± 2.123
2.801GlyIle: 2.801 ± 1.416
2.801GlyLys: 2.801 ± 1.416
5.602GlyLeu: 5.602 ± 2.831
1.401GlyMet: 1.401 ± 2.537
2.801GlyAsn: 2.801 ± 5.653
2.801GlyPro: 2.801 ± 1.416
1.401GlyGln: 1.401 ± 0.708
4.202GlyArg: 4.202 ± 2.123
2.801GlySer: 2.801 ± 1.416
1.401GlyThr: 1.401 ± 0.708
2.801GlyVal: 2.801 ± 5.653
4.202GlyTrp: 4.202 ± 2.123
4.202GlyTyr: 4.202 ± 4.945
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
2.801HisAsp: 2.801 ± 1.416
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
1.401HisHis: 1.401 ± 0.708
2.801HisIle: 2.801 ± 1.416
2.801HisLys: 2.801 ± 1.416
2.801HisLeu: 2.801 ± 5.653
0.0HisMet: 0.0 ± 0.0
1.401HisAsn: 1.401 ± 6.361
1.401HisPro: 1.401 ± 0.708
1.401HisGln: 1.401 ± 0.708
1.401HisArg: 1.401 ± 0.708
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.401HisTyr: 1.401 ± 0.708
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
0.0IleCys: 0.0 ± 0.0
2.801IleAsp: 2.801 ± 1.416
5.602IleGlu: 5.602 ± 11.305
1.401IlePhe: 1.401 ± 0.708
2.801IleGly: 2.801 ± 1.416
0.0IleHis: 0.0 ± 0.0
0.0IleIle: 0.0 ± 0.0
1.401IleLys: 1.401 ± 0.708
1.401IleLeu: 1.401 ± 0.708
1.401IleMet: 1.401 ± 0.708
1.401IleAsn: 1.401 ± 0.708
1.401IlePro: 1.401 ± 0.708
5.602IleGln: 5.602 ± 2.831
5.602IleArg: 5.602 ± 2.831
1.401IleSer: 1.401 ± 0.708
8.403IleThr: 8.403 ± 2.821
2.801IleVal: 2.801 ± 1.416
1.401IleTrp: 1.401 ± 0.708
1.401IleTyr: 1.401 ± 0.708
0.0IleXaa: 0.0 ± 0.0
Lys
2.801LysAla: 2.801 ± 1.416
0.0LysCys: 0.0 ± 0.0
2.801LysAsp: 2.801 ± 1.416
7.003LysGlu: 7.003 ± 3.539
2.801LysPhe: 2.801 ± 1.416
1.401LysGly: 1.401 ± 0.708
0.0LysHis: 0.0 ± 0.0
8.403LysIle: 8.403 ± 4.247
1.401LysLys: 1.401 ± 0.708
1.401LysLeu: 1.401 ± 0.708
1.401LysMet: 1.401 ± 0.708
5.602LysAsn: 5.602 ± 2.831
0.0LysPro: 0.0 ± 0.0
2.801LysGln: 2.801 ± 1.416
8.403LysArg: 8.403 ± 4.247
4.202LysSer: 4.202 ± 2.123
4.202LysThr: 4.202 ± 2.123
0.0LysVal: 0.0 ± 0.0
2.801LysTrp: 2.801 ± 1.416
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
0.0LeuAla: 0.0 ± 0.0
4.202LeuCys: 4.202 ± 4.945
7.003LeuAsp: 7.003 ± 17.666
5.602LeuGlu: 5.602 ± 2.831
5.602LeuPhe: 5.602 ± 2.831
1.401LeuGly: 1.401 ± 0.708
0.0LeuHis: 0.0 ± 0.0
2.801LeuIle: 2.801 ± 1.416
4.202LeuLys: 4.202 ± 2.123
0.0LeuLeu: 0.0 ± 0.0
1.401LeuMet: 1.401 ± 0.708
4.202LeuAsn: 4.202 ± 2.123
2.801LeuPro: 2.801 ± 1.416
2.801LeuGln: 2.801 ± 5.653
2.801LeuArg: 2.801 ± 1.416
2.801LeuSer: 2.801 ± 1.416
4.202LeuThr: 4.202 ± 4.945
2.801LeuVal: 2.801 ± 1.416
1.401LeuTrp: 1.401 ± 0.708
2.801LeuTyr: 2.801 ± 5.653
0.0LeuXaa: 0.0 ± 0.0
Met
2.801MetAla: 2.801 ± 1.416
0.0MetCys: 0.0 ± 0.0
2.801MetAsp: 2.801 ± 1.416
0.0MetGlu: 0.0 ± 0.0
1.401MetPhe: 1.401 ± 6.361
1.401MetGly: 1.401 ± 0.708
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
1.401MetLeu: 1.401 ± 0.708
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.401MetPro: 1.401 ± 0.708
0.0MetGln: 0.0 ± 0.0
2.801MetArg: 2.801 ± 1.416
0.0MetSer: 0.0 ± 0.0
1.401MetThr: 1.401 ± 0.708
0.0MetVal: 0.0 ± 0.0
1.401MetTrp: 1.401 ± 0.708
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.401AsnAla: 1.401 ± 0.708
0.0AsnCys: 0.0 ± 0.0
4.202AsnAsp: 4.202 ± 2.123
4.202AsnGlu: 4.202 ± 2.123
2.801AsnPhe: 2.801 ± 1.416
1.401AsnGly: 1.401 ± 0.708
0.0AsnHis: 0.0 ± 0.0
1.401AsnIle: 1.401 ± 0.708
2.801AsnLys: 2.801 ± 1.416
4.202AsnLeu: 4.202 ± 4.945
1.401AsnMet: 1.401 ± 0.708
2.801AsnAsn: 2.801 ± 1.416
5.602AsnPro: 5.602 ± 2.831
1.401AsnGln: 1.401 ± 0.708
1.401AsnArg: 1.401 ± 0.708
0.0AsnSer: 0.0 ± 0.0
2.801AsnThr: 2.801 ± 1.416
2.801AsnVal: 2.801 ± 1.416
4.202AsnTrp: 4.202 ± 4.945
2.801AsnTyr: 2.801 ± 1.416
0.0AsnXaa: 0.0 ± 0.0
Pro
1.401ProAla: 1.401 ± 0.708
1.401ProCys: 1.401 ± 0.708
2.801ProAsp: 2.801 ± 1.416
0.0ProGlu: 0.0 ± 0.0
2.801ProPhe: 2.801 ± 1.416
4.202ProGly: 4.202 ± 4.945
1.401ProHis: 1.401 ± 0.708
2.801ProIle: 2.801 ± 1.416
2.801ProLys: 2.801 ± 1.416
7.003ProLeu: 7.003 ± 3.539
0.0ProMet: 0.0 ± 0.0
1.401ProAsn: 1.401 ± 0.708
8.403ProPro: 8.403 ± 4.247
2.801ProGln: 2.801 ± 1.416
4.202ProArg: 4.202 ± 2.123
4.202ProSer: 4.202 ± 2.123
2.801ProThr: 2.801 ± 1.416
4.202ProVal: 4.202 ± 2.123
1.401ProTrp: 1.401 ± 0.708
1.401ProTyr: 1.401 ± 0.708
0.0ProXaa: 0.0 ± 0.0
Gln
1.401GlnAla: 1.401 ± 0.708
2.801GlnCys: 2.801 ± 1.416
0.0GlnAsp: 0.0 ± 0.0
5.602GlnGlu: 5.602 ± 2.831
1.401GlnPhe: 1.401 ± 0.708
4.202GlnGly: 4.202 ± 2.123
1.401GlnHis: 1.401 ± 0.708
1.401GlnIle: 1.401 ± 0.708
2.801GlnLys: 2.801 ± 1.416
4.202GlnLeu: 4.202 ± 4.945
0.0GlnMet: 0.0 ± 0.0
1.401GlnAsn: 1.401 ± 0.708
7.003GlnPro: 7.003 ± 3.539
1.401GlnGln: 1.401 ± 0.708
4.202GlnArg: 4.202 ± 4.945
2.801GlnSer: 2.801 ± 1.416
2.801GlnThr: 2.801 ± 1.416
1.401GlnVal: 1.401 ± 0.708
1.401GlnTrp: 1.401 ± 0.708
1.401GlnTyr: 1.401 ± 0.708
0.0GlnXaa: 0.0 ± 0.0
Arg
5.602ArgAla: 5.602 ± 2.831
1.401ArgCys: 1.401 ± 6.361
2.801ArgAsp: 2.801 ± 1.416
4.202ArgGlu: 4.202 ± 4.945
2.801ArgPhe: 2.801 ± 1.416
2.801ArgGly: 2.801 ± 1.416
1.401ArgHis: 1.401 ± 0.708
4.202ArgIle: 4.202 ± 2.123
8.403ArgLys: 8.403 ± 4.247
4.202ArgLeu: 4.202 ± 4.945
0.0ArgMet: 0.0 ± 0.0
4.202ArgAsn: 4.202 ± 2.123
7.003ArgPro: 7.003 ± 3.539
4.202ArgGln: 4.202 ± 2.123
37.815ArgArg: 37.815 ± 19.111
2.801ArgSer: 2.801 ± 1.416
2.801ArgThr: 2.801 ± 1.416
5.602ArgVal: 5.602 ± 2.831
7.003ArgTrp: 7.003 ± 3.539
8.403ArgTyr: 8.403 ± 4.247
0.0ArgXaa: 0.0 ± 0.0
Ser
2.801SerAla: 2.801 ± 1.416
0.0SerCys: 0.0 ± 0.0
1.401SerAsp: 1.401 ± 0.708
4.202SerGlu: 4.202 ± 2.123
0.0SerPhe: 0.0 ± 0.0
4.202SerGly: 4.202 ± 2.123
0.0SerHis: 0.0 ± 0.0
2.801SerIle: 2.801 ± 1.416
2.801SerLys: 2.801 ± 1.416
0.0SerLeu: 0.0 ± 0.0
0.0SerMet: 0.0 ± 0.0
2.801SerAsn: 2.801 ± 1.416
2.801SerPro: 2.801 ± 1.416
1.401SerGln: 1.401 ± 0.708
2.801SerArg: 2.801 ± 1.416
4.202SerSer: 4.202 ± 2.123
4.202SerThr: 4.202 ± 2.123
2.801SerVal: 2.801 ± 1.416
0.0SerTrp: 0.0 ± 0.0
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.202ThrAla: 4.202 ± 4.945
0.0ThrCys: 0.0 ± 0.0
8.403ThrAsp: 8.403 ± 9.89
4.202ThrGlu: 4.202 ± 2.123
1.401ThrPhe: 1.401 ± 0.708
2.801ThrGly: 2.801 ± 1.416
1.401ThrHis: 1.401 ± 0.708
5.602ThrIle: 5.602 ± 4.237
1.401ThrLys: 1.401 ± 0.708
4.202ThrLeu: 4.202 ± 2.123
0.0ThrMet: 0.0 ± 0.0
0.0ThrAsn: 0.0 ± 0.0
0.0ThrPro: 0.0 ± 0.0
5.602ThrGln: 5.602 ± 2.831
0.0ThrArg: 0.0 ± 0.0
4.202ThrSer: 4.202 ± 2.123
5.602ThrThr: 5.602 ± 4.237
2.801ThrVal: 2.801 ± 1.416
1.401ThrTrp: 1.401 ± 0.708
2.801ThrTyr: 2.801 ± 1.416
0.0ThrXaa: 0.0 ± 0.0
Val
4.202ValAla: 4.202 ± 12.013
1.401ValCys: 1.401 ± 0.708
1.401ValAsp: 1.401 ± 0.708
2.801ValGlu: 2.801 ± 1.416
1.401ValPhe: 1.401 ± 0.708
1.401ValGly: 1.401 ± 0.708
0.0ValHis: 0.0 ± 0.0
1.401ValIle: 1.401 ± 0.708
2.801ValLys: 2.801 ± 1.416
0.0ValLeu: 0.0 ± 0.0
2.801ValMet: 2.801 ± 1.416
1.401ValAsn: 1.401 ± 0.708
2.801ValPro: 2.801 ± 1.416
4.202ValGln: 4.202 ± 2.123
5.602ValArg: 5.602 ± 2.831
0.0ValSer: 0.0 ± 0.0
2.801ValThr: 2.801 ± 1.416
5.602ValVal: 5.602 ± 2.831
1.401ValTrp: 1.401 ± 0.708
1.401ValTyr: 1.401 ± 0.708
0.0ValXaa: 0.0 ± 0.0
Trp
1.401TrpAla: 1.401 ± 0.708
1.401TrpCys: 1.401 ± 0.708
2.801TrpAsp: 2.801 ± 1.416
1.401TrpGlu: 1.401 ± 6.361
1.401TrpPhe: 1.401 ± 0.708
5.602TrpGly: 5.602 ± 2.831
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
2.801TrpLys: 2.801 ± 1.416
2.801TrpLeu: 2.801 ± 5.653
0.0TrpMet: 0.0 ± 0.0
1.401TrpAsn: 1.401 ± 0.708
1.401TrpPro: 1.401 ± 0.708
0.0TrpGln: 0.0 ± 0.0
8.403TrpArg: 8.403 ± 4.247
1.401TrpSer: 1.401 ± 0.708
0.0TrpThr: 0.0 ± 0.0
2.801TrpVal: 2.801 ± 1.416
4.202TrpTrp: 4.202 ± 2.123
1.401TrpTyr: 1.401 ± 6.361
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
1.401TyrCys: 1.401 ± 0.708
1.401TyrAsp: 1.401 ± 6.361
1.401TyrGlu: 1.401 ± 0.708
2.801TyrPhe: 2.801 ± 1.416
1.401TyrGly: 1.401 ± 0.708
2.801TyrHis: 2.801 ± 5.653
2.801TyrIle: 2.801 ± 1.416
2.801TyrLys: 2.801 ± 1.416
4.202TyrLeu: 4.202 ± 2.123
0.0TyrMet: 0.0 ± 0.0
2.801TyrAsn: 2.801 ± 1.416
4.202TyrPro: 4.202 ± 2.123
2.801TyrGln: 2.801 ± 1.416
7.003TyrArg: 7.003 ± 3.539
1.401TyrSer: 1.401 ± 0.708
0.0TyrThr: 0.0 ± 0.0
0.0TyrVal: 0.0 ± 0.0
2.801TyrTrp: 2.801 ± 5.653
1.401TyrTyr: 1.401 ± 0.708
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (715 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski