Amino acid dipepetide frequency for Tortoise microvirus 33

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.187AlaAla: 6.187 ± 3.785
0.773AlaCys: 0.773 ± 0.82
4.64AlaAsp: 4.64 ± 1.661
0.773AlaGlu: 0.773 ± 0.689
2.32AlaPhe: 2.32 ± 0.907
6.187AlaGly: 6.187 ± 2.497
0.773AlaHis: 0.773 ± 0.509
5.414AlaIle: 5.414 ± 2.056
5.414AlaLys: 5.414 ± 2.776
8.507AlaLeu: 8.507 ± 1.601
0.773AlaMet: 0.773 ± 0.689
6.187AlaAsn: 6.187 ± 3.006
4.64AlaPro: 4.64 ± 1.814
6.961AlaGln: 6.961 ± 3.033
7.734AlaArg: 7.734 ± 3.227
3.867AlaSer: 3.867 ± 1.356
4.64AlaThr: 4.64 ± 1.334
5.414AlaVal: 5.414 ± 0.801
1.547AlaTrp: 1.547 ± 0.676
3.094AlaTyr: 3.094 ± 1.748
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.547CysAsp: 1.547 ± 1.186
0.773CysGlu: 0.773 ± 0.82
0.773CysPhe: 0.773 ± 0.82
0.773CysGly: 0.773 ± 0.82
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.773CysLeu: 0.773 ± 0.82
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.773CysGln: 0.773 ± 0.509
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.547CysVal: 1.547 ± 1.64
0.0CysTrp: 0.0 ± 0.0
0.773CysTyr: 0.773 ± 0.509
0.0CysXaa: 0.0 ± 0.0
Asp
3.867AspAla: 3.867 ± 0.488
0.773AspCys: 0.773 ± 0.82
6.187AspAsp: 6.187 ± 3.858
2.32AspGlu: 2.32 ± 1.723
3.867AspPhe: 3.867 ± 2.035
4.64AspGly: 4.64 ± 1.733
0.0AspHis: 0.0 ± 0.0
1.547AspIle: 1.547 ± 0.908
3.867AspLys: 3.867 ± 1.606
7.734AspLeu: 7.734 ± 1.377
1.547AspMet: 1.547 ± 0.676
1.547AspAsn: 1.547 ± 1.006
5.414AspPro: 5.414 ± 1.724
2.32AspGln: 2.32 ± 0.907
1.547AspArg: 1.547 ± 1.377
6.961AspSer: 6.961 ± 1.276
4.64AspThr: 4.64 ± 3.054
4.64AspVal: 4.64 ± 1.604
0.773AspTrp: 0.773 ± 0.82
3.867AspTyr: 3.867 ± 1.435
0.0AspXaa: 0.0 ± 0.0
Glu
3.867GluAla: 3.867 ± 1.283
0.0GluCys: 0.0 ± 0.0
1.547GluAsp: 1.547 ± 1.186
3.094GluGlu: 3.094 ± 2.587
5.414GluPhe: 5.414 ± 1.637
1.547GluGly: 1.547 ± 0.676
0.773GluHis: 0.773 ± 0.509
3.094GluIle: 3.094 ± 1.564
3.094GluLys: 3.094 ± 1.022
0.0GluLeu: 0.0 ± 0.0
0.0GluMet: 0.0 ± 0.0
0.773GluAsn: 0.773 ± 0.509
1.547GluPro: 1.547 ± 1.186
2.32GluGln: 2.32 ± 0.907
4.64GluArg: 4.64 ± 1.338
4.64GluSer: 4.64 ± 1.36
2.32GluThr: 2.32 ± 0.983
3.094GluVal: 3.094 ± 1.258
1.547GluTrp: 1.547 ± 1.018
6.187GluTyr: 6.187 ± 1.206
0.0GluXaa: 0.0 ± 0.0
Phe
4.64PheAla: 4.64 ± 0.967
0.0PheCys: 0.0 ± 0.0
5.414PheAsp: 5.414 ± 1.57
3.094PheGlu: 3.094 ± 1.566
0.773PhePhe: 0.773 ± 0.689
3.094PheGly: 3.094 ± 1.332
0.773PheHis: 0.773 ± 0.889
3.094PheIle: 3.094 ± 0.453
3.094PheLys: 3.094 ± 1.248
3.094PheLeu: 3.094 ± 1.353
0.773PheMet: 0.773 ± 0.82
1.547PheAsn: 1.547 ± 0.676
0.773PhePro: 0.773 ± 0.509
0.0PheGln: 0.0 ± 0.0
5.414PheArg: 5.414 ± 1.123
6.187PheSer: 6.187 ± 1.58
3.867PheThr: 3.867 ± 0.965
3.094PheVal: 3.094 ± 1.237
1.547PheTrp: 1.547 ± 1.018
0.773PheTyr: 0.773 ± 0.509
0.0PheXaa: 0.0 ± 0.0
Gly
5.414GlyAla: 5.414 ± 2.071
0.773GlyCys: 0.773 ± 0.82
2.32GlyAsp: 2.32 ± 1.527
3.094GlyGlu: 3.094 ± 1.258
3.867GlyPhe: 3.867 ± 2.427
3.867GlyGly: 3.867 ± 1.472
2.32GlyHis: 2.32 ± 0.872
3.867GlyIle: 3.867 ± 1.28
2.32GlyLys: 2.32 ± 0.983
6.187GlyLeu: 6.187 ± 1.917
0.0GlyMet: 0.0 ± 0.0
1.547GlyAsn: 1.547 ± 1.006
0.773GlyPro: 0.773 ± 0.509
3.867GlyGln: 3.867 ± 1.801
3.867GlyArg: 3.867 ± 0.488
9.281GlySer: 9.281 ± 1.421
3.867GlyThr: 3.867 ± 1.801
1.547GlyVal: 1.547 ± 0.624
0.0GlyTrp: 0.0 ± 0.0
2.32GlyTyr: 2.32 ± 0.872
0.0GlyXaa: 0.0 ± 0.0
His
0.773HisAla: 0.773 ± 0.889
0.0HisCys: 0.0 ± 0.0
1.547HisAsp: 1.547 ± 0.624
0.773HisGlu: 0.773 ± 0.509
3.094HisPhe: 3.094 ± 1.353
1.547HisGly: 1.547 ± 1.018
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
3.867HisLeu: 3.867 ± 0.773
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.773HisPro: 0.773 ± 0.689
0.0HisGln: 0.0 ± 0.0
3.094HisArg: 3.094 ± 1.353
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
1.547HisVal: 1.547 ± 0.676
0.0HisTrp: 0.0 ± 0.0
1.547HisTyr: 1.547 ± 0.676
0.0HisXaa: 0.0 ± 0.0
Ile
3.867IleAla: 3.867 ± 1.801
0.0IleCys: 0.0 ± 0.0
4.64IleAsp: 4.64 ± 2.424
2.32IleGlu: 2.32 ± 0.872
3.867IlePhe: 3.867 ± 0.488
3.867IleGly: 3.867 ± 0.773
0.773IleHis: 0.773 ± 0.509
1.547IleIle: 1.547 ± 1.018
1.547IleLys: 1.547 ± 0.897
3.867IleLeu: 3.867 ± 0.965
3.094IleMet: 3.094 ± 1.219
2.32IleAsn: 2.32 ± 0.872
3.094IlePro: 3.094 ± 2.036
0.773IleGln: 0.773 ± 0.509
3.094IleArg: 3.094 ± 1.566
3.867IleSer: 3.867 ± 1.181
2.32IleThr: 2.32 ± 0.983
0.773IleVal: 0.773 ± 0.509
1.547IleTrp: 1.547 ± 0.624
3.094IleTyr: 3.094 ± 1.564
0.0IleXaa: 0.0 ± 0.0
Lys
4.64LysAla: 4.64 ± 1.784
0.773LysCys: 0.773 ± 0.82
4.64LysAsp: 4.64 ± 1.677
3.867LysGlu: 3.867 ± 3.365
3.094LysPhe: 3.094 ± 1.258
0.773LysGly: 0.773 ± 0.509
0.0LysHis: 0.0 ± 0.0
3.867LysIle: 3.867 ± 3.02
6.187LysLys: 6.187 ± 3.067
1.547LysLeu: 1.547 ± 0.676
1.547LysMet: 1.547 ± 0.897
3.094LysAsn: 3.094 ± 0.453
0.773LysPro: 0.773 ± 0.82
1.547LysGln: 1.547 ± 1.377
3.867LysArg: 3.867 ± 2.593
3.867LysSer: 3.867 ± 1.356
3.094LysThr: 3.094 ± 1.87
4.64LysVal: 4.64 ± 1.851
0.0LysTrp: 0.0 ± 0.0
2.32LysTyr: 2.32 ± 1.415
0.0LysXaa: 0.0 ± 0.0
Leu
8.507LeuAla: 8.507 ± 3.113
1.547LeuCys: 1.547 ± 0.908
6.961LeuAsp: 6.961 ± 2.365
4.64LeuGlu: 4.64 ± 1.392
3.867LeuPhe: 3.867 ± 1.973
8.507LeuGly: 8.507 ± 2.865
0.0LeuHis: 0.0 ± 0.0
5.414LeuIle: 5.414 ± 1.176
5.414LeuLys: 5.414 ± 2.534
1.547LeuLeu: 1.547 ± 0.897
0.0LeuMet: 0.0 ± 0.0
3.094LeuAsn: 3.094 ± 0.991
4.64LeuPro: 4.64 ± 2.029
6.961LeuGln: 6.961 ± 3.636
5.414LeuArg: 5.414 ± 1.592
9.281LeuSer: 9.281 ± 2.936
1.547LeuThr: 1.547 ± 1.186
6.187LeuVal: 6.187 ± 1.835
0.773LeuTrp: 0.773 ± 0.82
0.773LeuTyr: 0.773 ± 0.509
0.0LeuXaa: 0.0 ± 0.0
Met
1.547MetAla: 1.547 ± 1.018
0.0MetCys: 0.0 ± 0.0
1.547MetAsp: 1.547 ± 1.64
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
0.773MetGly: 0.773 ± 0.509
1.547MetHis: 1.547 ± 0.676
0.0MetIle: 0.0 ± 0.0
0.773MetLys: 0.773 ± 0.82
3.094MetLeu: 3.094 ± 1.816
0.773MetMet: 0.773 ± 0.889
1.547MetAsn: 1.547 ± 0.908
0.773MetPro: 0.773 ± 0.509
0.773MetGln: 0.773 ± 0.689
0.0MetArg: 0.0 ± 0.0
3.094MetSer: 3.094 ± 1.248
0.0MetThr: 0.0 ± 0.0
0.773MetVal: 0.773 ± 0.82
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
5.414AsnAla: 5.414 ± 2.282
0.0AsnCys: 0.0 ± 0.0
3.867AsnAsp: 3.867 ± 1.283
5.414AsnGlu: 5.414 ± 2.407
1.547AsnPhe: 1.547 ± 1.006
0.773AsnGly: 0.773 ± 0.509
0.0AsnHis: 0.0 ± 0.0
2.32AsnIle: 2.32 ± 0.907
2.32AsnLys: 2.32 ± 1.415
3.867AsnLeu: 3.867 ± 2.544
1.547AsnMet: 1.547 ± 1.018
0.773AsnAsn: 0.773 ± 0.509
0.773AsnPro: 0.773 ± 0.689
2.32AsnGln: 2.32 ± 1.212
2.32AsnArg: 2.32 ± 0.872
4.64AsnSer: 4.64 ± 1.677
1.547AsnThr: 1.547 ± 1.64
0.773AsnVal: 0.773 ± 0.509
0.773AsnTrp: 0.773 ± 0.82
0.773AsnTyr: 0.773 ± 0.82
0.0AsnXaa: 0.0 ± 0.0
Pro
5.414ProAla: 5.414 ± 1.315
0.773ProCys: 0.773 ± 0.82
3.094ProAsp: 3.094 ± 1.816
2.32ProGlu: 2.32 ± 1.527
3.867ProPhe: 3.867 ± 2.06
2.32ProGly: 2.32 ± 0.872
0.773ProHis: 0.773 ± 0.82
3.867ProIle: 3.867 ± 2.545
2.32ProLys: 2.32 ± 0.872
3.094ProLeu: 3.094 ± 0.955
1.547ProMet: 1.547 ± 1.018
4.64ProAsn: 4.64 ± 0.615
0.773ProPro: 0.773 ± 0.689
3.094ProGln: 3.094 ± 1.248
5.414ProArg: 5.414 ± 1.592
2.32ProSer: 2.32 ± 0.839
1.547ProThr: 1.547 ± 1.018
0.773ProVal: 0.773 ± 0.509
0.0ProTrp: 0.0 ± 0.0
1.547ProTyr: 1.547 ± 0.624
0.0ProXaa: 0.0 ± 0.0
Gln
5.414GlnAla: 5.414 ± 2.282
0.0GlnCys: 0.0 ± 0.0
0.773GlnAsp: 0.773 ± 0.82
3.094GlnGlu: 3.094 ± 1.564
2.32GlnPhe: 2.32 ± 0.907
1.547GlnGly: 1.547 ± 0.624
0.0GlnHis: 0.0 ± 0.0
1.547GlnIle: 1.547 ± 1.018
1.547GlnLys: 1.547 ± 1.377
5.414GlnLeu: 5.414 ± 2.407
0.0GlnMet: 0.0 ± 0.0
2.32GlnAsn: 2.32 ± 2.066
2.32GlnPro: 2.32 ± 1.527
4.64GlnGln: 4.64 ± 2.302
6.187GlnArg: 6.187 ± 2.215
3.094GlnSer: 3.094 ± 1.454
6.187GlnThr: 6.187 ± 1.851
3.094GlnVal: 3.094 ± 1.248
0.773GlnTrp: 0.773 ± 0.689
2.32GlnTyr: 2.32 ± 1.478
0.0GlnXaa: 0.0 ± 0.0
Arg
6.961ArgAla: 6.961 ± 1.703
0.0ArgCys: 0.0 ± 0.0
1.547ArgAsp: 1.547 ± 0.624
2.32ArgGlu: 2.32 ± 1.835
0.0ArgPhe: 0.0 ± 0.0
5.414ArgGly: 5.414 ± 1.71
1.547ArgHis: 1.547 ± 0.624
3.094ArgIle: 3.094 ± 1.258
2.32ArgLys: 2.32 ± 0.983
11.601ArgLeu: 11.601 ± 4.007
1.547ArgMet: 1.547 ± 0.879
2.32ArgAsn: 2.32 ± 0.495
6.961ArgPro: 6.961 ± 2.218
3.094ArgGln: 3.094 ± 0.709
4.64ArgArg: 4.64 ± 2.029
3.867ArgSer: 3.867 ± 1.709
3.094ArgThr: 3.094 ± 0.955
3.094ArgVal: 3.094 ± 0.709
0.773ArgTrp: 0.773 ± 0.689
5.414ArgTyr: 5.414 ± 0.829
0.0ArgXaa: 0.0 ± 0.0
Ser
8.507SerAla: 8.507 ± 2.665
0.773SerCys: 0.773 ± 0.82
6.961SerAsp: 6.961 ± 1.276
3.094SerGlu: 3.094 ± 1.564
5.414SerPhe: 5.414 ± 2.104
4.64SerGly: 4.64 ± 1.814
3.094SerHis: 3.094 ± 1.258
5.414SerIle: 5.414 ± 2.339
4.64SerLys: 4.64 ± 3.148
6.187SerLeu: 6.187 ± 2.218
0.773SerMet: 0.773 ± 0.743
0.773SerAsn: 0.773 ± 0.689
5.414SerPro: 5.414 ± 1.315
5.414SerGln: 5.414 ± 1.724
4.64SerArg: 4.64 ± 0.701
10.054SerSer: 10.054 ± 0.716
2.32SerThr: 2.32 ± 0.495
3.094SerVal: 3.094 ± 1.258
0.0SerTrp: 0.0 ± 0.0
2.32SerTyr: 2.32 ± 1.415
0.0SerXaa: 0.0 ± 0.0
Thr
3.867ThrAla: 3.867 ± 2.625
0.773ThrCys: 0.773 ± 0.509
3.867ThrAsp: 3.867 ± 1.282
3.867ThrGlu: 3.867 ± 1.606
0.0ThrPhe: 0.0 ± 0.0
5.414ThrGly: 5.414 ± 2.156
0.0ThrHis: 0.0 ± 0.0
2.32ThrIle: 2.32 ± 1.723
1.547ThrLys: 1.547 ± 0.624
5.414ThrLeu: 5.414 ± 2.104
0.773ThrMet: 0.773 ± 0.82
0.773ThrAsn: 0.773 ± 0.509
3.094ThrPro: 3.094 ± 1.332
1.547ThrGln: 1.547 ± 1.006
0.773ThrArg: 0.773 ± 0.689
6.187ThrSer: 6.187 ± 1.598
1.547ThrThr: 1.547 ± 1.186
2.32ThrVal: 2.32 ± 1.134
0.0ThrTrp: 0.0 ± 0.0
3.867ThrTyr: 3.867 ± 3.02
0.0ThrXaa: 0.0 ± 0.0
Val
3.094ValAla: 3.094 ± 1.353
0.773ValCys: 0.773 ± 0.82
3.867ValAsp: 3.867 ± 0.488
2.32ValGlu: 2.32 ± 1.134
2.32ValPhe: 2.32 ± 1.527
3.094ValGly: 3.094 ± 1.454
2.32ValHis: 2.32 ± 1.373
0.773ValIle: 0.773 ± 0.509
3.867ValLys: 3.867 ± 0.994
4.64ValLeu: 4.64 ± 0.701
0.0ValMet: 0.0 ± 0.0
3.094ValAsn: 3.094 ± 1.353
5.414ValPro: 5.414 ± 0.829
0.773ValGln: 0.773 ± 0.82
5.414ValArg: 5.414 ± 1.592
1.547ValSer: 1.547 ± 1.377
2.32ValThr: 2.32 ± 1.134
2.32ValVal: 2.32 ± 1.173
0.0ValTrp: 0.0 ± 0.0
2.32ValTyr: 2.32 ± 0.907
0.0ValXaa: 0.0 ± 0.0
Trp
0.773TrpAla: 0.773 ± 0.82
0.0TrpCys: 0.0 ± 0.0
0.773TrpAsp: 0.773 ± 0.509
1.547TrpGlu: 1.547 ± 1.018
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
1.547TrpHis: 1.547 ± 0.624
0.773TrpIle: 0.773 ± 0.509
0.0TrpLys: 0.0 ± 0.0
2.32TrpLeu: 2.32 ± 0.495
0.0TrpMet: 0.0 ± 0.0
0.773TrpAsn: 0.773 ± 0.689
1.547TrpPro: 1.547 ± 0.676
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.773TrpThr: 0.773 ± 0.82
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.094TyrAla: 3.094 ± 1.748
0.0TyrCys: 0.0 ± 0.0
2.32TyrAsp: 2.32 ± 1.173
0.773TyrGlu: 0.773 ± 0.889
4.64TyrPhe: 4.64 ± 1.745
2.32TyrGly: 2.32 ± 1.574
2.32TyrHis: 2.32 ± 1.415
2.32TyrIle: 2.32 ± 0.872
3.867TyrLys: 3.867 ± 1.998
2.32TyrLeu: 2.32 ± 0.872
1.547TyrMet: 1.547 ± 0.908
4.64TyrAsn: 4.64 ± 0.615
0.0TyrPro: 0.0 ± 0.0
5.414TyrGln: 5.414 ± 2.407
2.32TyrArg: 2.32 ± 1.415
0.773TyrSer: 0.773 ± 0.509
2.32TyrThr: 2.32 ± 0.983
1.547TyrVal: 1.547 ± 1.64
0.773TyrTrp: 0.773 ± 0.509
2.32TyrTyr: 2.32 ± 0.872
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1294 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski